eprinomectin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiparasitics, ivermectin derivatives 5533 123997-26-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • eprinomectin
  • eprinex
  • MK-397
  • Molecular weight: 900.12
  • Formula: C49H73NO14
  • CLOGP: 3.61
  • LIPINSKI: 3
  • HAC: 15
  • HDO: 3
  • TPSA: 178.93
  • ALOGS: -5.08
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000871 Anthelmintics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000977 Antiparasitic Agents
MeSH PA D007306 Insecticides
MeSH PA D010575 Pesticides
CHEBI has role CHEBI:35442 antiparasitic drugs
CHEBI has role CHEBI:35444 antinematodal drugs
CHEBI has role CHEBI:36053 acaricide drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Cattle Treatment and control of gastrointestinal roundworms, (Haemonchus placei (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, Ostertagia ostertagi (adult and L4, including inhibited L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, Trichostrongylus axei (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, T colubriformis (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, T longispicularis (adult) Indication
Cattle Treatment and control of gastrointestinal roundworms, Cooperia oncophora (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, C punctate (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, C surnabada (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, Nematodirus helvetianus (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, Bunostomum phlebotomum (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, Oesophagostomum radiatum (adult and L4) Indication
Cattle Treatment and control of gastrointestinal roundworms, Strongyloides papillosus (adults) Indication
Cattle Treatment and control of gastrointestinal roundworms, Trichuris species (adults)) Indication
Cattle Treatment and control of lungworms, Dictyocaulus viviparus, (adult and L4) Indication
Cattle Treatment and control of grubs, Hypoderma lineatum|Treatment and control of grubs, H bovis) Indication
Cattle Treatment and control of lice, Damalinia bovis Indication
Cattle Treatment and control of lice, Linognathus vituli Indication
Cattle Treatment and control of lice, Haematopinus eurysternus Indication
Cattle Treatment and control of lice, Solenopotes capillatus Indication
Cattle Treatment and control of mange mites, Chorioptes bovis Indication
Cattle Treatment and control of mange mites, Sarcoptes scabiei Indication
Cattle Treatment and control of horn flies, Haematobia irritans Indication
Cattle Protection (21 days) from reinfection of D viviparous Indication
Cattle Protection (7 days) from reinfection of H irritans Indication
Cattle Treatment and control of grubs, H bovis Indication

🐶 Veterinary products

ProductApplicantIngredients
Eprinex Pour-On for Beef and Dairy Cattle Boehringer lngelheim Animal Health USA Inc. 1
Longrange Boehringer lngelheim Animal Health USA Inc. 1
Centragard Boehringer lngelheim Animal Health USA Inc. 2
Eprizero Norbrook Laboratories, Ltd. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:82596 CHEBI
CHEMBL3989594 ChEMBL_ID
C101434 MESH_SUPPLEMENTAL_RECORD_UI
DB11405 DRUGBANK_ID
017998 NDDF
C0529813 UMLSCUI
7371 INN_ID
D04037 KEGG_DRUG
6450531 PUBCHEM_CID
1006619 RXNORM
75KP30FD8O UNII

Pharmaceutical products:

None