doramectin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiparasitics, ivermectin derivatives 5528 117704-25-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • doramectin
  • dectomax
  • L-701023
  • NSC-760342
  • Molecular weight: 899.13
  • Formula: C50H74O14
  • CLOGP: 4.51
  • LIPINSKI: 3
  • HAC: 14
  • HDO: 3
  • TPSA: 170.06
  • ALOGS: -5.18
  • ROTB: 7

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000871 Anthelmintics
MeSH PA D014151 Anti-Anxiety Agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000927 Anticonvulsants
MeSH PA D000977 Antiparasitic Agents
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D007306 Insecticides
MeSH PA D010575 Pesticides
MeSH PA D011619 Psychotropic Drugs
MeSH PA D014149 Tranquilizing Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Cattle Treatment and control of the gastrointestinal roundworms, Ostertagia ostertagi (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Ostertagia ostertagi (Inhibited fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Ostertagia lyrata (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Haemonchus placei (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Trichostrongylus axei (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Trichostrongylus colubriformis (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Trichostrongylus longispicularis (Adults) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Cooperia oncophora (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Cooperia punctata (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Cooperia pectinata (Adults) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Cooperia surnabada (syn mcmasteri) (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Bunostomum phlebotomum (Adults) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Strongyloides papillosus (Adults) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Oesophagostomum radiatum (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the gastrointestinal roundworms, Trichuris spp (Adults) Indication
Cattle Treatment and control of the lungworms, Dictyocaulus viviparus (Adults and fourth-stage larvae) Indication
Cattle Treatment and control of the eyeworms, Thelazia spp (Adults) Indication
Cattle Treatment and control of grubs, Hypoderma bovis Indication
Cattle Treatment and control of lice, Haematopinus eurysternus Indication
Cattle Treatment and control of lice, Linognathus vituli Indication
Cattle Treatment and control of lice, Solenopotes capillatus Indication
Cattle Treatment and control of lice, Mange mites Indication
Cattle Treatment and control of lice, Psoroptes bovis Indication
Cattle Treatment and control of lice, Sarcoptes scabiei Indication
Cattle Protection (14 days) from reinfection with Cooperia oncophora Indication
Cattle Protection (14 days) from reinfection with Haemonchus placei Indication
Cattle Protection (21 days) from reinfection with Ostertagia ostertagi Indication
Cattle Protection (28 days) from reinfection with Cooperia punctata Indication
Cattle Protection (28 days) from reinfection with Oesophagostomum radiatum Indication
Cattle Protection (28 days) from reinfection with Dictyocaulus viviparus Indication
Cattle Treatment and control of grubs, Hypoderma lineatum Indication
Swine Treatment and control of gastrointestinal roundworms, Hyostrongylus rubidus (Adults) Indication
Swine Treatment and control of gastrointestinal roundworms, Ascaris suum (Adults, and fourth-stage larvae) Indication
Swine Treatment and control of gastrointestinal roundworms, Oesophagostomum dentatum (Adults, and fourth-stage larvae) Indication
Swine Treatment and control of gastrointestinal roundworms, Oesophagostomum quadrispinulatum (Adults) Indication
Swine Treatment and control of gastrointestinal roundworms, Strongyloides ransomi (Adults) Indication
Swine Treatment and control of lungworms, Metastrongylus spp (Adults) Indication
Swine Treatment and control of kidneyworms, Stephanurus dentatus (Adults) Indication
Swine Treatment and control of sucking lice, Haematopinus suis (Adults and Immature stages) Indication
Swine Treatment and control of mites, Sarcoptes scabiei var suis (Adults and Immature stages) Indication

🐶 Veterinary products

ProductApplicantIngredients
Dectomax Injectable Solution for Cattle and Swine Zoetis Inc. 1
Dectomax Pour-on Solution for Cattle Zoetis Inc. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:31516 CHEBI
CHEMBL2361641 ChEMBL_ID
C084101 MESH_SUPPLEMENTAL_RECORD_UI
DB11400 DRUGBANK_ID
C0248572 UMLSCUI
6630 INN_ID
D01129 KEGG_DRUG
9832750 PUBCHEM_CID
73454 RXNORM
KGD7A54H5P UNII

Pharmaceutical products:

None