teceleukin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
interleukin-2 analogues and derivatives 5484 136279-32-8

Description:

MoleculeDescription

Molfile

Synonyms:

  • teceleukin
  • teceleukin (genetical recombination)
  • imunace
  • BG 8301
  • bioleukin
  • S-6820
a recombinant IL-2 product having a methionine added at the N-terminal.
  • Molecular weight: 15547.22
  • Formula: C698H1127N179O204S8
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 6216.69
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 31, 1992 PMDA SHIONOGI & Co., Ltd.

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hypoalbuminaemia 92.28 71.73 23 551 17651 64480507

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Enhancement of an antitumor effect of dinutuximab for neuroblastoma indication 432328008 DOID:769




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Interleukin-2 receptor Membrane receptor BINDING AGENT UNKNOWN KEGG DRUG

External reference:

IDSource
CHEMBL2107892 ChEMBL_ID
5838 INN_ID
DB15389 DRUGBANK_ID
H5ZRB188EI UNII
D02749 KEGG_DRUG
65181 PUBCHEM_CID
C2825351 UMLSCUI

Pharmaceutical products:

None