Molfile
Inchi
Smiles
Synonyms:
-
bremelanotide
-
bremelanotide acetate
-
vyleesi
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PT-141
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Bremelanotide is a melanocortin receptor (MCR) agonist that nonselectively activates several receptor subtypes with the following order of potency: MC1R, MC4R, MC3R, MC5R, MC2R. The mechanism by which VYLEESI improves HSDD in women is unknown. The MC1R is expressed on melanocytes; binding at this receptor leads to melanin expression and increased pigmentation
- Molecular weight: 1025.18
- Formula: C50H68N14O10
- CLOGP: -1.79
- LIPINSKI: 3
- HAC: 24
- HDO: 13
- TPSA: 378.97
- ALOGS: -4.73
- ROTB: 17
- Status: ONP
Legend: OFP - off patent OFM - off market ONP - on patent
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