netarsudil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
Rho protein kinase inhibitors 5269 1254032-66-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • rhokiinsa
  • netarsudil
  • netarsudil dimesylate
  • netarsudil mesylate
  • rhopressa
  • AR-13324
Netarsudil is a rho kinase inhibitor, which is believed to reduce IOP by increasing the outflow of aqueous humor through the trabecular meshwork route.
  • Molecular weight: 453.54
  • Formula: C28H27N3O3
  • CLOGP: 5.01
  • LIPINSKI: 1
  • HAC: 6
  • HDO: 2
  • TPSA: 94.31
  • ALOGS: -6.21
  • ROTB: 8
  • Status: ONP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

netarsudil