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tasonermin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
tumour necrosis factor	5212	94948-59-1

Description:

Molecule	Description
Synonyms: tasonermin beromun	Tasonermin, is a copy of the human protein tumour necrosis factor alfa-1a (TNF-alfa). The exact way that TNF-alfa works against certain types of cancer is not fully understood, but it is thought that it can kill tumour cells directly, as well as destroy the blood vessels supplying tumours and stimulate the immune system to attack them. This leads to the tumour dying back and getting smaller, particularly when the medicine is combined with other cytotoxic (cell-killing) medicines and raised temperature. Molecular weight: 17350.75 Formula: C778H1225N215O231S2 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 7163.87 ALOGS: ROTB: None

Molecule

Description

Synonyms:

tasonermin
beromun

Tasonermin, is a copy of the human protein tumour necrosis factor alfa-1a (TNF-alfa). The exact way that TNF-alfa works against certain types of cancer is not fully understood, but it is thought that it can kill tumour cells directly, as well as destroy the blood vessels supplying tumours and stimulate the immune system to attack them. This leads to the tumour dying back and getting smaller, particularly when the medicine is combined with other cytotoxic (cell-killing) medicines and raised temperature.

Molecular weight: 17350.75
Formula: C778H1225N215O231S2
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 7163.87
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
3.50	mg	P

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
April 13, 1999	EMA	Boehringer Ingelheim International GmbH

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	L03AX11	ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSTIMULANTS IMMUNOSTIMULANTS Other immunostimulants

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Sarcoma of soft tissue	indication	424952003

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
23CA79S88F	UNII
C0937851	UMLSCUI
CHEMBL2107891	ChEMBL_ID
DB11626	DRUGBANK_ID
D08562	KEGG_DRUG
7581	INN_ID
008935	NDDF
421147008	SNOMEDCT_US
421457001	SNOMEDCT_US
283746	RXNORM

Pharmaceutical products:

None