corticorelin ovine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5195 79804-71-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • corticotropin-releasing hormone (ovine)
  • ovine ACTH releasing factor
  • corticorelin ovine
  • corticorelin ovine triflutate
  • acthrel
used in diagnosis of adrenocortical insufficiency & Cushing's syndrome; AA sequence given in first source; MF C205-H339-N59-O63-S; RN given refers to triflutate salt; RN for parent cpd not avail 3/94
  • Molecular weight: 4670.38
  • Formula: C205H339N59O63S
  • CLOGP:
  • LIPINSKI: None
  • HAC: 122
  • HDO: 66
  • TPSA: 1989.13
  • ALOGS:
  • ROTB: 159

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
May 23, 1996 FDA FERRING

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:33295 diagnostic aid

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.12 acidic
pKa2 3.45 acidic
pKa3 3.7 acidic
pKa4 4.05 acidic
pKa5 4.3 acidic
pKa6 4.88 acidic
pKa7 11.87 acidic
pKa8 12.28 acidic
pKa9 12.46 acidic
pKa10 12.47 acidic
pKa11 12.61 acidic
pKa12 12.75 acidic
pKa13 12.83 acidic
pKa14 12.99 acidic
pKa15 13.1 acidic
pKa16 13.14 acidic
pKa17 13.18 acidic
pKa18 13.28 acidic
pKa19 13.33 acidic
pKa20 13.44 acidic
pKa21 13.52 acidic
pKa22 13.54 acidic
pKa23 13.58 acidic
pKa24 13.6 acidic
pKa25 13.7 acidic
pKa26 13.75 acidic
pKa27 13.86 acidic
pKa28 13.87 acidic
pKa29 13.89 acidic
pKa30 13.91 acidic
pKa31 11.38 Basic
pKa32 10.97 Basic
pKa33 10.59 Basic
pKa34 10.18 Basic
pKa35 7.66 Basic
pKa36 6.99 Basic
pKa37 6.39 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
Y124TZ0513 UNII
C0251516 UMLSCUI
CHEBI:65307 CHEBI
16132344 PUBCHEM_CID
DB09067 DRUGBANK_ID
D03592 KEGG_DRUG
CHEMBL1201591 ChEMBL_ID
74670 RXNORM
4505 MMSL
6021 MMSL
109205007 SNOMEDCT_US
398935003 SNOMEDCT_US
4021062 VANDF
4024084 VANDF
006761 NDDF
007306 NDDF
C085671 MESH_SUPPLEMENTAL_RECORD_UI
121249-14-7 SECONDARY_CAS_RN

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Acthrel HUMAN PRESCRIPTION DRUG LABEL 1 55566-0302 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 100 ug INTRAVENOUS BLA 19 sections