hydrocortisone phosphate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
corticosteroids, except prednisolone derivatives 5193 3863-59-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hydrocortisone phosphate
  • hydrocortisone sodium phosphate
  • hydrocortone phosphate
  • hydrocortisone disodium phosphate
  • cortisol sodium phosphate
  • Molecular weight: 442.45
  • Formula: C21H31O8P
  • CLOGP: 0.42
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 4
  • TPSA: 141.36
  • ALOGS: -2.78
  • ROTB: 4
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 0.23 mg/mL Bocci G, Oprea TI, Benet LZ

Approvals:

DateAgencyCompanyOrphan
June 8, 1960 FDA MERCK

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:49167 anti-asthmatic drugs
CHEBI has role CHEBI:50857 anti-allergic drugs
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:77746 Homo sapiens metabolite
CHEBI has role CHEBI:88188 allergenic drug

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.75 acidic
pKa2 6.8 acidic
pKa3 13.47 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
2Y87E22X71 UNII
D00977 KEGG_DRUG
6000-74-4 SECONDARY_CAS_RN
4017941 VANDF
4017943 VANDF
C0056383 UMLSCUI
CHEBI:5781 CHEBI
CHEBI:17650 CHEBI
CHEMBL1641 ChEMBL_ID
441407 PUBCHEM_CID
DB14542 DRUGBANK_ID
CHEMBL1200968 ChEMBL_ID
C039803 MESH_SUPPLEMENTAL_RECORD_UI
DB00741 DRUGBANK_ID
1021 MMSL
2500 MMSL
4837 MMSL
4842 MMSL
72410 MMSL
d00254 MMSL
002147 NDDF
002151 NDDF
109064002 SNOMEDCT_US
16602005 SNOMEDCT_US
396458002 SNOMEDCT_US
C0020268 UMLSCUI
38 INN_ID
5754 PUBCHEM_CID
217629 RXNORM
D006854 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None