insulin beef 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	5192	11070-73-8

Description:

Molecule

Description

Synonyms:

insulin (beef)
insulin beef
insulin purified beef
insulin susp isophane beef
insulin susp isophane purified beef
insulin susp protamine zinc beef
insulin susp protamine zinc purified beef
insulin zinc susp beef
insulin zinc susp extended beef
insulin zinc susp extended purified beef
insulin zinc susp prompt beef
insulin zinc susp purified beef

Molecular weight: 5733.55
Formula: C254H377N65O75S6
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 2258.61
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
40	U	P
40	U	P
40	U	P
40	U	P

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Hypoglycaemia	46.80	22.83	25	1575	60040	63427382
Gait inability	43.96	22.83	23	1577	52936	63434486
Toothache	40.54	22.83	16	1584	19183	63468239
Pharyngitis	36.36	22.83	15	1585	20128	63467294
Blood aldosterone abnormal	28.26	22.83	4	1596	46	63487376
BRASH syndrome	25.26	22.83	5	1595	464	63486958
Diabetic metabolic decompensation	23.67	22.83	6	1594	1704	63485718

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Hypoglycaemia	42.70	22.35	26	1265	54614	34901026

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Hypoglycaemia	77.60	20.57	48	2953	101546	79639841
Toothache	33.72	20.57	16	2985	19954	79721433
Gait inability	30.77	20.57	22	2979	58895	79682492
Hyperglycaemia	29.45	20.57	23	2978	70312	79671075
Pharyngitis	29.08	20.57	15	2986	22360	79719027
Blood aldosterone abnormal	26.65	20.57	4	2997	46	79741341
Acute myocardial infarction	23.54	20.57	21	2980	77015	79664372
Blood glucose increased	23.25	20.57	25	2976	114950	79626437

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A10AB02	ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES INSULINS AND ANALOGUES Insulins and analogues for injection, fast-acting
ATC	A10AC02	ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES INSULINS AND ANALOGUES Insulins and analogues for injection, intermediate-acting
ATC	A10AD02	ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES INSULINS AND ANALOGUES Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting
ATC	A10AE02	ALIMENTARY TRACT AND METABOLISM DRUGS USED IN DIABETES INSULINS AND ANALOGUES Insulins and analogues for injection, long-acting

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
576O9IZ534	UNII
C0304866	UMLSCUI
DB09456	DRUGBANK_ID
CHEMBL1201629	ChEMBL_ID
CHEMBL1201545	ChEMBL_ID
CHEMBL1201655	ChEMBL_ID
CHEMBL1201541	ChEMBL_ID
CHEMBL1201639	ChEMBL_ID
CHEMBL1201640	ChEMBL_ID
CHEMBL1201542	ChEMBL_ID
CHEMBL1201642	ChEMBL_ID
CHEMBL1201546	ChEMBL_ID
000867	NDDF
000868	NDDF
126208003	SNOMEDCT_US
4700006	SNOMEDCT_US
24839622	PUBCHEM_CID

Pharmaceutical products:

None