talc 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5190 14807-96-6

Description:

MoleculeDescription

Synonyms:

  • talc
  • sterile talc
  • unitalc
Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed)
  • Molecular weight: 379.26
  • Formula: H2Mg3O12Si4
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 63.19
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA
Sept. 23, 2013 PMDA Nobelpharma Co., Ltd.

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D051520 Antiperspirants
MeSH PA D003358 Cosmetics

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Inoperable secondary intractable pneumothorax indication 328571000119101
Suppression of recurrence of malignant pleural effusions indication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
2GM/VIAL STERITALC NOVATECH SA N205555 May 1, 2017 RX POWDER INTRAPLEURAL May 1, 2024 TO DECREASE THE RECURRENCE OF MALIGNANT PLEURAL EFFUSIONS IN SYMPTOMATIC PATIENTS FOLLOWING MAXIMAL DRAINAGE OF THE PLEURAL EFFUSION
2GM/VIAL STERITALC NOVATECH SA N205555 May 1, 2017 RX POWDER INTRAPLEURAL May 1, 2024 TO DECREASE THE RECURRENCE OF PNEUMOTHORAX IN ADULTS
3GM/VIAL STERITALC NOVATECH SA N205555 May 1, 2017 RX POWDER INTRAPLEURAL May 1, 2024 TO DECREASE THE RECURRENCE OF MALIGNANT PLEURAL EFFUSIONS IN SYMPTOMATIC PATIENTS FOLLOWING MAXIMAL DRAINAGE OF THE PLEURAL EFFUSION
3GM/VIAL STERITALC NOVATECH SA N205555 May 1, 2017 RX POWDER INTRAPLEURAL May 1, 2024 TO DECREASE THE RECURRENCE OF PNEUMOTHORAX IN ADULTS
4GM/VIAL STERITALC NOVATECH SA N205555 May 1, 2017 RX POWDER INTRAPLEURAL May 1, 2024 TO DECREASE THE RECURRENCE OF MALIGNANT PLEURAL EFFUSIONS IN SYMPTOMATIC PATIENTS FOLLOWING MAXIMAL DRAINAGE OF THE PLEURAL EFFUSION
4GM/VIAL STERITALC NOVATECH SA N205555 May 1, 2017 RX POWDER INTRAPLEURAL May 1, 2024 TO DECREASE THE RECURRENCE OF PNEUMOTHORAX IN ADULTS

Bioactivity Summary:

None

External reference:

IDSource
7SEV7J4R1U UNII
D01084 KEGG_DRUG
4019447 VANDF
C0039267 UMLSCUI
CHEBI:32178 CHEBI
CHEMBL3989756 ChEMBL_ID
CHEMBL3990276 ChEMBL_ID
DB09511 DRUGBANK_ID
D013627 MESH_DESCRIPTOR_UI
17014 MMSL
NOCODE MMSL
d04822 MMSL
001919 NDDF
1557002 SNOMEDCT_US
409109009 SNOMEDCT_US
10323 RXNORM

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Baby HUMAN OTC DRUG LABEL 1 0363-0901 POWDER 100 g TOPICAL OTC monograph not final 9 sections
Natures Choice Baby HUMAN OTC DRUG LABEL 1 43749-112 POWDER 99 g TOPICAL OTC monograph not final 7 sections
Pan Aromas Baby HUMAN OTC DRUG LABEL 1 50346-004 POWDER 1 g TOPICAL OTC monograph not final 8 sections
FACE IT HD PERFECT BB SPF30 PA 01 HUMAN OTC DRUG LABEL 5 51523-103 CREAM 0.68 mL TOPICAL OTC monograph not final 7 sections
FACE IT HD PERFECT BB SPF30 PA 02 HUMAN OTC DRUG LABEL 5 51523-104 CREAM 0.68 mL TOPICAL OTC monograph not final 7 sections
Health Smart Baby HUMAN OTC DRUG LABEL 1 52862-010 POWDER 1 g TOPICAL OTC monograph not final 9 sections
OHUI Sun Science Sun Block EX plus Beige HUMAN OTC DRUG LABEL 6 53208-524 POWDER 55.49 g TOPICAL OTC monograph not final 5 sections
Steritalc2g HUMAN PRESCRIPTION DRUG LABEL 1 62327-222 POWDER 2 g INTRAPLEURAL NDA 14 sections
Steritalc2g HUMAN PRESCRIPTION DRUG LABEL 1 62327-222 POWDER 2 g INTRAPLEURAL NDA 14 sections
Steritalc3g HUMAN PRESCRIPTION DRUG LABEL 1 62327-333 POWDER 3 g INTRAPLEURAL NDA 14 sections
Steritalc3g HUMAN PRESCRIPTION DRUG LABEL 1 62327-333 POWDER 3 g INTRAPLEURAL NDA 14 sections
Steritalc4g HUMAN PRESCRIPTION DRUG LABEL 1 62327-444 POWDER 4 g INTRAPLEURAL NDA 14 sections
Steritalc4g HUMAN PRESCRIPTION DRUG LABEL 1 62327-444 POWDER 4 g INTRAPLEURAL NDA 14 sections
Sclerosol HUMAN PRESCRIPTION DRUG LABEL 1 63256-100 AEROSOL, POWDER 4 g INTRAPLEURAL NDA 21 sections
Sterile Talc HUMAN PRESCRIPTION DRUG LABEL 1 63256-200 POWDER 5 g INTRAPLEURAL NDA 18 sections
SPAI-SONSFINE TALCUM HUMAN OTC DRUG LABEL 2 66854-018 POWDER 81 g TOPICAL OTC monograph not final 8 sections