talc 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	5190	14807-96-6

Description:

Molecule	Description
Synonyms: talc sterile talc unitalc	Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed) Molecular weight: 379.26 Formula: H2Mg3O12Si4 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 63.19 ALOGS: ROTB: None

Molecule

Description

Synonyms:

talc
sterile talc
unitalc

Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed)

Molecular weight: 379.26
Formula: H2Mg3O12Si4
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 63.19
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA
Sept. 23, 2013	PMDA	Nobelpharma Co., Ltd.

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D051520	Antiperspirants
MeSH PA	D003358	Cosmetics

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Inoperable secondary intractable pneumothorax	indication	328571000119101
Suppression of recurrence of malignant pleural effusions	indication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

Formulation strength	Trade name	Applicant	Application number	Approval date	Type	Dose form	Route	Exclusivity date	Description
2GM/VIAL	STERITALC	NOVATECH SA	N205555	May 1, 2017	RX	POWDER	INTRAPLEURAL	May 1, 2024	TO DECREASE THE RECURRENCE OF MALIGNANT PLEURAL EFFUSIONS IN SYMPTOMATIC PATIENTS FOLLOWING MAXIMAL DRAINAGE OF THE PLEURAL EFFUSION
2GM/VIAL	STERITALC	NOVATECH SA	N205555	May 1, 2017	RX	POWDER	INTRAPLEURAL	May 1, 2024	TO DECREASE THE RECURRENCE OF PNEUMOTHORAX IN ADULTS
3GM/VIAL	STERITALC	NOVATECH SA	N205555	May 1, 2017	RX	POWDER	INTRAPLEURAL	May 1, 2024	TO DECREASE THE RECURRENCE OF MALIGNANT PLEURAL EFFUSIONS IN SYMPTOMATIC PATIENTS FOLLOWING MAXIMAL DRAINAGE OF THE PLEURAL EFFUSION
3GM/VIAL	STERITALC	NOVATECH SA	N205555	May 1, 2017	RX	POWDER	INTRAPLEURAL	May 1, 2024	TO DECREASE THE RECURRENCE OF PNEUMOTHORAX IN ADULTS
4GM/VIAL	STERITALC	NOVATECH SA	N205555	May 1, 2017	RX	POWDER	INTRAPLEURAL	May 1, 2024	TO DECREASE THE RECURRENCE OF MALIGNANT PLEURAL EFFUSIONS IN SYMPTOMATIC PATIENTS FOLLOWING MAXIMAL DRAINAGE OF THE PLEURAL EFFUSION
4GM/VIAL	STERITALC	NOVATECH SA	N205555	May 1, 2017	RX	POWDER	INTRAPLEURAL	May 1, 2024	TO DECREASE THE RECURRENCE OF PNEUMOTHORAX IN ADULTS

Bioactivity Summary:

None

External reference:

ID	Source
7SEV7J4R1U	UNII
D01084	KEGG_DRUG
4019447	VANDF
C0039267	UMLSCUI
CHEBI:32178	CHEBI
CHEMBL3989756	ChEMBL_ID
CHEMBL3990276	ChEMBL_ID
DB09511	DRUGBANK_ID
D013627	MESH_DESCRIPTOR_UI
17014	MMSL
NOCODE	MMSL
d04822	MMSL
001919	NDDF
1557002	SNOMEDCT_US
409109009	SNOMEDCT_US
10323	RXNORM

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Baby	HUMAN OTC DRUG LABEL	1	0363-0901	POWDER	100 g	TOPICAL	OTC monograph not final	9 sections
Natures Choice Baby	HUMAN OTC DRUG LABEL	1	43749-112	POWDER	99 g	TOPICAL	OTC monograph not final	7 sections
Pan Aromas Baby	HUMAN OTC DRUG LABEL	1	50346-004	POWDER	1 g	TOPICAL	OTC monograph not final	8 sections
FACE IT HD PERFECT BB SPF30 PA 01	HUMAN OTC DRUG LABEL	5	51523-103	CREAM	0.68 mL	TOPICAL	OTC monograph not final	7 sections
FACE IT HD PERFECT BB SPF30 PA 02	HUMAN OTC DRUG LABEL	5	51523-104	CREAM	0.68 mL	TOPICAL	OTC monograph not final	7 sections
Health Smart Baby	HUMAN OTC DRUG LABEL	1	52862-010	POWDER	1 g	TOPICAL	OTC monograph not final	9 sections
OHUI Sun Science Sun Block EX plus Beige	HUMAN OTC DRUG LABEL	6	53208-524	POWDER	55.49 g	TOPICAL	OTC monograph not final	5 sections
Steritalc2g	HUMAN PRESCRIPTION DRUG LABEL	1	62327-222	POWDER	2 g	INTRAPLEURAL	NDA	14 sections
Steritalc2g	HUMAN PRESCRIPTION DRUG LABEL	1	62327-222	POWDER	2 g	INTRAPLEURAL	NDA	14 sections
Steritalc3g	HUMAN PRESCRIPTION DRUG LABEL	1	62327-333	POWDER	3 g	INTRAPLEURAL	NDA	14 sections
Steritalc3g	HUMAN PRESCRIPTION DRUG LABEL	1	62327-333	POWDER	3 g	INTRAPLEURAL	NDA	14 sections
Steritalc4g	HUMAN PRESCRIPTION DRUG LABEL	1	62327-444	POWDER	4 g	INTRAPLEURAL	NDA	14 sections
Steritalc4g	HUMAN PRESCRIPTION DRUG LABEL	1	62327-444	POWDER	4 g	INTRAPLEURAL	NDA	14 sections
Sclerosol	HUMAN PRESCRIPTION DRUG LABEL	1	63256-100	AEROSOL, POWDER	4 g	INTRAPLEURAL	NDA	21 sections
Sterile Talc	HUMAN PRESCRIPTION DRUG LABEL	1	63256-200	POWDER	5 g	INTRAPLEURAL	NDA	18 sections
SPAI-SONSFINE TALCUM	HUMAN OTC DRUG LABEL	2	66854-018	POWDER	81 g	TOPICAL	OTC monograph not final	8 sections