rubidium Rb-82 chloride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	5184	132486-03-4

Description:

Molecule	Description
Synonyms: rubidium chloride Rb-82 rubidium Rb-82 chloride RUBY-FILL Rubidium Chloride Rb 82 rubidium (82Rb) chloride CARDIOGEN-82	Rb-82 is analogous to potassium ion (K+) in its biochemical behavior and is rapidly extracted by the myocardium proportional to the blood flow. Rb+ participates in the sodium-potassium (Na+/K+) ion exchange pumps that are present in cell membranes. The intracellular uptake of Rb-82 requires maintenance of ionic gradient across cell membranes. Rb-82 radioactivity is increased in viable myocardium reflecting intracellular retention, while the tracer is cleared rapidly from necrotic or infarcted tissue. Molecular weight: 117.37 Formula: ClRb CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Molecule

Description

Synonyms:

rubidium chloride Rb-82
rubidium Rb-82 chloride
RUBY-FILL
Rubidium Chloride Rb 82
rubidium (82Rb) chloride
CARDIOGEN-82

Rb-82 is analogous to potassium ion (K+) in its biochemical behavior and is rapidly extracted by the myocardium proportional to the blood flow. Rb+ participates in the sodium-potassium (Na+/K+) ion exchange pumps that are present in cell membranes. The intracellular uptake of Rb-82 requires maintenance of ionic gradient across cell membranes. Rb-82 radioactivity is increased in viable myocardium reflecting intracellular retention, while the tracer is cleared rapidly from necrotic or infarcted tissue.

Molecular weight: 117.37
Formula: ClRb
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Dec. 29, 1989	FDA	BRACCO

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Product preparation error	199.76	184.02	25	31	5768	79738564

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	V09GX04	VARIOUS DIAGNOSTIC RADIOPHARMACEUTICALS CARDIOVASCULAR SYSTEM Other cardiovascular system diagnostic radiopharmaceuticals

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Positron emission tomography	indication	82918005

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
CHEMBL1200727	ChEMBL_ID
D05773	KEGG_DRUG
71357	PUBCHEM_CID
1367086	RXNORM
213493	MMSL
30242	MMSL
d08248	MMSL
C1268555	UMLSCUI
F0Z746KRKQ	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
CardioGen-82	HUMAN PRESCRIPTION DRUG LABEL	1	0270-0091	INJECTION, SOLUTION	150 mCi	INTRAVENOUS	NDA	25 sections
CardioGen-82	HUMAN PRESCRIPTION DRUG LABEL	1	0270-0091	INJECTION, SOLUTION	150 mCi	INTRAVENOUS	NDA	25 sections
RUBY-FILL	Human Prescription Drug Label	1	65174-021	INJECTION, SOLUTION	100 mCi	INTRAVENOUS	NDA	24 sections