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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5184 | 132486-03-4 |
| Molecule | Description |
|---|---|
|
Synonyms:
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Rb-82 is analogous to potassium ion (K+) in its biochemical behavior and is rapidly extracted by the myocardium proportional to the blood flow. Rb+ participates in the sodium-potassium (Na+/K+) ion exchange pumps that are present in cell membranes. The intracellular uptake of Rb-82 requires maintenance of ionic gradient across cell membranes. Rb-82 radioactivity is increased in viable myocardium reflecting intracellular retention, while the tracer is cleared rapidly from necrotic or infarcted tissue.
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| Date | Agency | Company | Orphan |
|---|---|---|---|
| Dec. 29, 1989 | FDA | BRACCO |
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| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Product preparation error | 190.47 | 185.17 | 25 | 34 | 10854 | 110578386 |
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| Source | Code | Description |
|---|---|---|
| ATC | V09GX04 | VARIOUS DIAGNOSTIC RADIOPHARMACEUTICALS CARDIOVASCULAR SYSTEM Other cardiovascular system diagnostic radiopharmaceuticals |
| CHEBI has role | CHEBI:35554 | cardiovascular drug |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Positron emission tomography | indication | 82918005 |
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| ID | Source |
|---|---|
| C1268555 | UMLSCUI |
| CHEBI:749308 | CHEBI |
| CHEMBL1200727 | ChEMBL_ID |
| D05773 | KEGG_DRUG |
| 71357 | PUBCHEM_CID |
| 213493 | MMSL |
| 30242 | MMSL |
| d08248 | MMSL |
| 019528 | NDDF |
| F0Z746KRKQ | UNII |
| 1367086 | RXNORM |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| CardioGen-82 | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0270-0091 | INJECTION, SOLUTION | 150 mCi | INTRAVENOUS | NDA | 24 sections |
| RUBY-FILL | Human Prescription Drug Label | 1 | 65174-021 | INJECTION, SOLUTION | 100 mCi | INTRAVENOUS | NDA | 24 sections |