alipogene tiparvovec 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
gene therapy products 5172 929881-05-0

Description:

MoleculeDescription

Synonyms:

  • alipogene tiparvovec
  • glybera
gene therapy product, contains the human lipoprotein lipase (LPL) gene variant LPLS447X in a vector comprised of a protein shell derived from adeno-associated virus serotype 1 (AAV1), the Cytomegalovirus (CMV) promoter, a woodchuck hepatitis virus posttranscriptional regulatory element and AAV2 derived inverted terminal repeats
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Oct. 25, 2012 EMA uniQure biopharma B.V.

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C10AX10 CARDIOVASCULAR SYSTEM
LIPID MODIFYING AGENTS
LIPID MODIFYING AGENTS, PLAIN
Other lipid modifying agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Familial lipoprotein lipase deficiency indication 238086005




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
20OK4AFR4Y UNII
C3653189 UMLSCUI
CHEMBL2108304 ChEMBL_ID
838 PUBCHEM_CID
DB13521 DRUGBANK_ID
8987 INN_ID
016036 NDDF
C000721108 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None