pancrelipase 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
enzymes	5161	53608-75-6

Description:

Molecule	Description
Synonyms: pancrelipase pancreatin pancreatic extract pancrelipase	A standardized enzyme concentrate containing the pancreatic enzymes, lipase, protease and amylase used in enzyme substitution therapy. Lipase, protease and amylase break down fat, protein, and starches, respectively in the small intestine, thereby promoting digestion. Pancrelipase is used to reduce malabsorption when the pancreas is unable to secrete sufficient amounts of these enzymes. Molecular weight: Formula: CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Molecule

Description

Synonyms:

pancrelipase
pancreatin
pancreatic extract pancrelipase

A standardized enzyme concentrate containing the pancreatic enzymes, lipase, protease and amylase used in enzyme substitution therapy. Lipase, protease and amylase break down fat, protein, and starches, respectively in the small intestine, thereby promoting digestion. Pancrelipase is used to reduce malabsorption when the pancreas is unable to secrete sufficient amounts of these enzymes.

Molecular weight:
Formula:
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Angina bullosa haemorrhagica	67.40	15.93	12	7082	132	63481796
Needle issue	59.20	15.93	27	7067	10349	63471579
Muscle swelling	52.84	15.93	12	7082	474	63481454
Facial asymmetry	46.82	15.93	12	7082	793	63481135
Vulval disorder	45.87	15.93	12	7082	860	63481068
Early satiety	44.29	15.93	12	7082	984	63480944
Infective pulmonary exacerbation of cystic fibrosis	41.22	15.93	20	7074	8797	63473131
Body temperature decreased	34.90	15.93	24	7070	20295	63461633
Fracture blisters	32.63	15.93	6	7088	80	63481848
Breast pain	32.46	15.93	17	7077	8781	63473147

Showing 1 to 10 of 50 entries

Previous1 2 3 4 5Next

FDA Adverse Event Reporting System (Male)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Infective pulmonary exacerbation of cystic fibrosis	83.52	17.65	35	6286	6766	34943844
General physical health deterioration	61.14	17.65	94	6227	128175	34822435
Enterocolitis infectious	59.75	17.65	19	6302	1676	34948934
Pancreatic carcinoma	47.99	17.65	26	6295	8875	34941735
Abdominal pain upper	37.71	17.65	55	6266	71435	34879175
Toxic optic neuropathy	36.14	17.65	11	6310	839	34949771
Pancreatic carcinoma metastatic	35.65	17.65	15	6306	2925	34947685
Diarrhoea	33.49	17.65	149	6172	389763	34560847
Rash morbilliform	31.68	17.65	14	6307	3073	34947537
Abdominal pain	31.40	17.65	82	6239	163536	34787074

Showing 1 to 10 of 31 entries

Previous1 2 3 4Next

FDA Adverse Event Reporting System (Geriatric)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Infective pulmonary exacerbation of cystic fibrosis	105.40	14.94	48	12700	12803	79718837
Pancreatic carcinoma	81.71	14.94	41	12707	13536	79718104
Needle issue	77.29	14.94	39	12709	13029	79718611
General physical health deterioration	72.32	14.94	145	12603	275093	79456547
Pancreatic carcinoma metastatic	50.75	14.94	20	12728	3733	79727907
Angina bullosa haemorrhagica	46.50	14.94	10	12738	211	79731429
Liver abscess	44.61	14.94	21	12727	6033	79725607
Body temperature decreased	43.21	14.94	38	12710	32107	79699533
Abdominal pain upper	41.86	14.94	103	12645	223716	79507924
Diarrhoea	40.25	14.94	259	12489	880230	78851410

Showing 1 to 10 of 66 entries

Previous1 2 3 4 5 6 7Next

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D005765	Gastrointestinal Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Exocrine pancreatic insufficiency	indication	47367009	DOID:13316

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

Show entries

Search:

ID	Source
001234	NDDF
001235	NDDF
12236006	SNOMEDCT_US
235379	RXNORM
387049005	SNOMEDCT_US
387265002	SNOMEDCT_US
4018109	VANDF
4018414	VANDF
41216	MMSL
48647005	SNOMEDCT_US

Showing 1 to 10 of 21 entries

Previous1 2 3Next

Pharmaceutical products:

Show entries

Search:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
FESTAL PLUS	HUMAN OTC DRUG LABEL	3	72689-0010	TABLET	315 mg	ORAL	unapproved drug other	6 sections
Stozyme	HUMAN OTC DRUG LABEL	4	72850-0004	TABLET	36.46 1	ORAL	unapproved drug other	7 sections

Showing 1 to 2 of 2 entries

Previous1Next