Gallium Ga 68 dotatate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5156 1051369-72-2

Description:

MoleculeDescription

Synonyms:

  • Gallium Ga 68 dotatate
  • (68Ga)gallium dotatate
  • netspot
A radioactive diagnostic agent used for POSITRON EMISSION TOMOGRAPHY (PET) imaging of SOMATOSTATIN RECEPTOR positive neuroendocrine tumors and malignant abdominal paraganglioma.
  • Molecular weight: 1500.54
  • Formula: C65H87GaN14O19S2
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 468.57
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
June 1, 2016 FDA ADVANCED ACCELERATOR APPLICATIONS USA INC

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Scan gallium abnormal 142.23 85.81 13 182 16 64498521
Nausea 124.69 85.81 54 141 785746 63712791

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Positron emission tomography indication 82918005




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
2.1-5.5mCi/ML NETSPOT AAA USA INC N208547 June 1, 2016 RX POWDER INTRAVENOUS June 1, 2023 FOR USE AFTER RADIOLABELING WITH GA 68, WITH POSITRON EMISSION TOMOGRAPHY (PET) FOR LOCALIZATION OF SOMATOSTATIN RECEPTOR POSITIVE NEUROENDOCRINE TUMORS (NETS) IN ADULT AND PEDIATRIC PATIENTS.

Bioactivity Summary:

None

External reference:

IDSource
4038246 VANDF
C1742831 UMLSCUI
131634491 PUBCHEM_CID
CHEMBL4297340 ChEMBL_ID
DB13925 DRUGBANK_ID
676679 RXNORM
241192 MMSL
C513399 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None