technetium (99mTc) sestamibi 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5124 109581-73-9

Description:

MoleculeDescription

Synonyms:

  • technetium (99mTc) sestamibi
  • cardiolite
  • technetium Tc-99m sestamibi
  • technetium Tc 99m sestamibi
  • technetium (99m Tc) sestamibi
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
  • Molecular weight: 777.87
  • Formula: C36H66N6O6Tc
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 81.54
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 21, 1990 FDA LANTHEUS MEDCL

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug ineffective 56.59 45.88 47 331 1044718 62443926
Scan myocardial perfusion abnormal 46.40 45.88 5 373 24 63488620

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug ineffective 78.07 44.30 49 278 456702 34499902
Scan myocardial perfusion abnormal 77.14 44.30 9 318 59 34956545

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Scan myocardial perfusion abnormal 85.95 38.59 10 626 76 79743676
Drug ineffective 42.53 38.59 47 589 1080866 78662886

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V09GA01 VARIOUS
DIAGNOSTIC RADIOPHARMACEUTICALS
CARDIOVASCULAR SYSTEM
Technetium (99mTc) compounds
FDA MoA N0000000205 Radiopharmaceutical Activity
FDA EPC N0000177914 Radioactive Diagnostic Agent
MeSH PA D064907 Diagnostic Uses of Chemicals
MeSH PA D007202 Indicators and Reagents
MeSH PA D019275 Radiopharmaceuticals

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Radionuclide myocardial perfusion study indication 252432008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4030044 VANDF
C0162680 UMLSCUI
CHEBI:9423 CHEBI
CHEMBL4594241 ChEMBL_ID
5384 PUBCHEM_CID
DB09161 DRUGBANK_ID
1482913 RXNORM
194283 MMSL
424299003 SNOMEDCT_US
D017256 MESH_DESCRIPTOR_UI
6243 INN_ID
971Z4W1S09 UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
TECHNETIUM TC 99M SESTAMIBI HUMAN PRESCRIPTION DRUG LABEL 1 45548-141 INJECTION, POWDER, FOR SOLUTION 1 mg INTRAVENOUS ANDA 32 sections
TECHNETIUM TC 99M SESTAMIBI HUMAN PRESCRIPTION DRUG LABEL 1 45548-141 INJECTION, POWDER, FOR SOLUTION 1 mg INTRAVENOUS ANDA 32 sections
Kit for the Preparation of Technetium Tc99m Sestamibi HUMAN PRESCRIPTION DRUG LABEL 1 45567-0555 INJECTION 1 mg INTRAVENOUS ANDA 24 sections
Kit for the Preparation of Technetium Tc99m Sestamibi HUMAN PRESCRIPTION DRUG LABEL 1 65857-500 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 1 mg PARENTERAL ANDA 31 sections
Kit for the Preparation of Technetium Tc99m Sestamibi HUMAN PRESCRIPTION DRUG LABEL 1 65857-500 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 1 mg PARENTERAL ANDA 31 sections