technetium (99mTc) sestamibi 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5124 109581-73-9

Description:

MoleculeDescription

Synonyms:

  • technetium (99mTc) sestamibi
  • cardiolite
  • technetium Tc-99m sestamibi
  • technetium Tc 99m sestamibi
  • technetium (99m Tc) sestamibi
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
  • Molecular weight: 777.87
  • Formula: C36H66N6O6Tc
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 81.54
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 21, 1990 FDA LANTHEUS MEDCL

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug ineffective 57.54 46.93 44 278 819289 49785513

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Scan myocardial perfusion abnormal 76.86 45.46 9 277 59 29574182
Drug ineffective 76.49 45.46 45 241 363125 29211116

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Scan myocardial perfusion abnormal 86.16 39.00 10 513 73 64498136

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V09GA01 VARIOUS
DIAGNOSTIC RADIOPHARMACEUTICALS
CARDIOVASCULAR SYSTEM
Technetium (99mTc) compounds
FDA MoA N0000000205 Radiopharmaceutical Activity
FDA EPC N0000177914 Radioactive Diagnostic Agent
MeSH PA D064907 Diagnostic Uses of Chemicals
MeSH PA D007202 Indicators and Reagents
MeSH PA D019275 Radiopharmaceuticals

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Radionuclide myocardial perfusion study indication 252432008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4030044 VANDF
C0162680 UMLSCUI
CHEBI:9423 CHEBI
CHEMBL4594241 ChEMBL_ID
22617237 PUBCHEM_CID
DB09161 DRUGBANK_ID
971Z4W1S09 UNII
1482913 RXNORM
194283 MMSL
424299003 SNOMEDCT_US
D017256 MESH_DESCRIPTOR_UI
6243 INN_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
TECHNETIUM TC 99M SESTAMIBI HUMAN PRESCRIPTION DRUG LABEL 1 45548-141 INJECTION, POWDER, FOR SOLUTION 1 mg INTRAVENOUS ANDA 32 sections
TECHNETIUM TC 99M SESTAMIBI HUMAN PRESCRIPTION DRUG LABEL 1 45548-141 INJECTION, POWDER, FOR SOLUTION 1 mg INTRAVENOUS ANDA 32 sections
Kit for the Preparation of Technetium Tc99m Sestamibi HUMAN PRESCRIPTION DRUG LABEL 1 45567-0555 INJECTION 1 mg INTRAVENOUS ANDA 24 sections
Kit for the Preparation of Technetium Tc99m Sestamibi HUMAN PRESCRIPTION DRUG LABEL 1 65857-500 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 1 mg PARENTERAL ANDA 31 sections