technetium Tc 99m tetrofosmin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
insecticides, anthelminthics, pesticides etc., phosphorous derivatives 5123 127455-27-0

Description:

MoleculeDescription

Synonyms:

  • technetium Tc 99m tetrofosmin
  • myoview
  • technetium Tc-99m tetrofosmin
  • Molecular weight: 895.83
  • Formula: C36H80O10P4Tc
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 107.98
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Feb. 9, 1996 FDA GE HEALTHCARE

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
No adverse event 286.67 81.48 56 162 41349 63447455
Radioisotope scan abnormal 277.47 81.48 29 189 204 63488600

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Radioisotope scan abnormal 381.18 81.83 41 178 203 34956509
No adverse event 349.82 81.83 66 153 22861 34933851

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
No adverse event 359.25 59.55 69 265 37123 79706931
Radioisotope scan abnormal 305.20 59.55 35 299 495 79743559
Drug ineffective 60.66 59.55 43 291 1080870 78663184

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000000205 Radiopharmaceutical Activity
MeSH PA D064907 Diagnostic Uses of Chemicals
MeSH PA D007202 Indicators and Reagents
MeSH PA D019275 Radiopharmaceuticals
FDA EPC N0000177914 Radioactive Diagnostic Agent

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Radionuclide myocardial perfusion study indication 252432008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
42FOP1YX93 UNII
4034261 VANDF
C0211492 UMLSCUI
CHEMBL1200857 ChEMBL_ID
4274 PUBCHEM_CID
DB09160 DRUGBANK_ID
C078700 MESH_SUPPLEMENTAL_RECORD_UI
192668 MMSL
009759 NDDF
424118002 SNOMEDCT_US

Pharmaceutical products:

None