chromic chloride Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5118 10025-73-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chromic chloride
  • chromic trichloride
  • chromium trichloride
  • chromic chloride hexahydrate
Trivalent chromium is part of glucose tolerance factor, an activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function.
  • Molecular weight: 158.35
  • Formula: Cl3Cr
  • CLOGP:
  • LIPINSKI: None
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS:
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
June 26, 1986 FDA HOSPIRA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:39143 lewis acid
CHEBI has role CHEBI:139492 sensitizer

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Tyrosine-protein kinase Fyn Kinase IC50 5.76 CHEMBL
Epidermal growth factor receptor Kinase IC50 5.53 CHEMBL

External reference:

IDSource
10060-12-5 SECONDARY_CAS_RN
D03479 KEGG_DRUG
4018528 VANDF
4018529 VANDF
4018530 VANDF
C0055617 UMLSCUI
CHEBI:53351 CHEBI
CHEMBL1200528 ChEMBL_ID
DB09129 DRUGBANK_ID
C022990 MESH_SUPPLEMENTAL_RECORD_UI
104957 PUBCHEM_CID
KB1PCR9DMW UNII
21009 RXNORM
29 MMSL
4439 MMSL
d04250 MMSL
000862 NDDF
007501 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CHROMIUM HUMAN PRESCRIPTION DRUG LABEL 1 0409-4093 INJECTION, SOLUTION 4 ug INTRAVENOUS NDA 20 sections
CHROMIUM HUMAN PRESCRIPTION DRUG LABEL 1 0409-4093 INJECTION, SOLUTION 4 ug INTRAVENOUS NDA 20 sections
Multitrace-4 Neonatal HUMAN PRESCRIPTION DRUG LABEL 4 0517-6202 INJECTION, SOLUTION 4.36 ug INTRAVENOUS UNULLPPROVED DRUG OTHER 14 sections
Multitrace-5 HUMAN PRESCRIPTION DRUG LABEL 5 0517-8201 INJECTION, SOLUTION, CONCENTRATE 51.30 ug INTRAVENOUS UNULLPPROVED DRUG OTHER 14 sections
Multitrace-5 HUMAN PRESCRIPTION DRUG LABEL 5 0517-8210 INJECTION, SOLUTION, CONCENTRATE 51.30 ug INTRAVENOUS UNULLPPROVED DRUG OTHER 14 sections
Multitrace-5 HUMAN PRESCRIPTION DRUG LABEL 5 0517-8510 INJECTION, SOLUTION 20.50 ug INTRAVENOUS UNULLPPROVED DRUG OTHER 14 sections
Multitrace -4 Pediatric HUMAN PRESCRIPTION DRUG LABEL 4 0517-9203 INJECTION, SOLUTION, CONCENTRATE 5.12 ug INTRAVENOUS UNULLPPROVED DRUG OTHER 14 sections
Trace Elements 4 HUMAN PRESCRIPTION DRUG LABEL 4 0517-9310 INJECTION, SOLUTION 5.12 ug INTRAVENOUS UNULLPPROVED DRUG OTHER 14 sections
CHROMIUM CHROMIC CHLORIDE HUMAN PRESCRIPTION DRUG LABEL 1 51662-1415 INJECTION, SOLUTION 4 ug INTRAVENOUS NDA 13 sections