beractant 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5108 108778-82-1

Description:

MoleculeDescription

Synonyms:

  • beractant
  • survanta
a bovine lung extract that contains mostly phospholipids; modified by the addition of dipalmitoylphosphatidylcholine, palmitic acid, and tripalmitin
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 1, 1991 FDA ABBVIE

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pulmonary haemorrhage 208.85 119.63 30 67 6462 50598565

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pulmonary haemorrhage 267.12 93.56 44 98 9226 29565159

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pulmonary haemorrhage 207.67 141.46 45 24 267 84342

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000000079 Surfactant Activity
FDA PE N0000008294 Alveolar Surface Tension Reduction
MeSH PA D011663 Pulmonary Surfactants
MeSH PA D019141 Respiratory System Agents
FDA EPC N0000175778 Surfactant

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Respiratory distress syndrome in the newborn indication 46775006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
S866O45PIG UNII
D03096 KEGG_DRUG
4020026 VANDF
C0105750 UMLSCUI
CHEMBL1201624 ChEMBL_ID
DB06761 DRUGBANK_ID
C072197 MESH_SUPPLEMENTAL_RECORD_UI
202963 RXNORM
4268 MMSL
d00777 MMSL
387225001 SNOMEDCT_US
40905005 SNOMEDCT_US
003601 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Survanta HUMAN PRESCRIPTION DRUG LABEL 1 0074-1040 SUSPENSION 25 mg ENDOTRACHEAL BLA 15 sections