beractant 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	5108	108778-82-1

Description:

Molecule

Description

Synonyms:

beractant
survanta

a bovine lung extract that contains mostly phospholipids; modified by the addition of dipalmitoylphosphatidylcholine, palmitic acid, and tripalmitin

Molecular weight:
Formula:
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
July 1, 1991	FDA	ABBVIE

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Pulmonary haemorrhage	212.63	121.47	30	67	7151	63481774

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Pulmonary haemorrhage	269.82	94.35	44	98	10260	34946529

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Pulmonary haemorrhage	206.98	137.37	45	24	291	89432

Pharmacologic Action:

Source	Code	Description
FDA MoA	N0000000079	Surfactant Activity
FDA PE	N0000008294	Alveolar Surface Tension Reduction
MeSH PA	D011663	Pulmonary Surfactants
MeSH PA	D019141	Respiratory System Agents
FDA EPC	N0000175778	Surfactant

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Respiratory distress syndrome in the newborn	indication	46775006

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
S866O45PIG	UNII
D03096	KEGG_DRUG
4020026	VANDF
C0105750	UMLSCUI
CHEMBL1201624	ChEMBL_ID
DB06761	DRUGBANK_ID
C072197	MESH_SUPPLEMENTAL_RECORD_UI
202963	RXNORM
4268	MMSL
d00777	MMSL
003601	NDDF
387225001	SNOMEDCT_US
40905005	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Survanta	HUMAN PRESCRIPTION DRUG LABEL	1	0074-1040	SUSPENSION	25 mg	ENDOTRACHEAL	BLA	15 sections
Survanta	HUMAN PRESCRIPTION DRUG LABEL	1	0074-1040	SUSPENSION	25 mg	ENDOTRACHEAL	BLA	15 sections