nonoxinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	5107	26027-38-3

Description:

Molecule	Description
Synonyms: nonoxinol nonoxynol 9 nonoxynol-9 nonoxynol 4,9,15,30	Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams. Molecular weight: Formula: C15H24O(C2H4O)n CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Molecule

Description

Synonyms:

nonoxinol
nonoxynol 9
nonoxynol-9
nonoxynol 4,9,15,30

Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.

Molecular weight:
Formula: C15H24O(C2H4O)n
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Dec. 10, 1963	FDA	PERSONAL PRODS

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
CHEBI has role	CHEBI:38828	non-ionic surfactant
CHEBI has role	CHEBI:49323	contraceptive drugs
MeSH PA	D000988	Antispermatogenic Agents
MeSH PA	D003270	Contraceptive Agents
MeSH PA	D003271	Contraceptive Agents, Female
MeSH PA	D009676	Noxae
MeSH PA	D012102	Reproductive Control Agents
MeSH PA	D013089	Spermatocidal Agents
MeSH PA	D013501	Surface-Active Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Contraception	indication	13197004

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4018924	VANDF
4021065	VANDF
C0068943	UMLSCUI
CHEBI:53775	CHEBI
CHEMBL2108472	ChEMBL_ID
7700	PUBCHEM_CID
CHEMBL1410	ChEMBL_ID
DB06804	DRUGBANK_ID
53750	RXNORM
5185	MMSL
001328	NDDF
007492	NDDF
326454008	SNOMEDCT_US
397179004	SNOMEDCT_US
D017137	MESH_DESCRIPTOR_UI
48Q180SH9T	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
ConceptrolOptions	HUMAN OTC DRUG LABEL	1	34362-0300	GEL	4 g	VAGINAL	OTC monograph not final	9 sections
Gynol IIExtra Strength	HUMAN OTC DRUG LABEL	1	34362-0302	GEL	3 g	VAGINAL	OTC monograph not final	9 sections
Today Vaginal Contraceptive	HUMAN OTC DRUG LABEL	1	44376-100	SPONGE	1000 mg	VAGINAL	NDA	16 sections
VCF CONTRACEPTIVE	HUMAN OTC DRUG LABEL	1	52925-112	FILM, SOLUBLE	280 mg	VAGINAL	OTC MONOGRAPH NOT FINAL	14 sections
VCF CONTRACEPTIVE	HUMAN OTC DRUG LABEL	1	52925-112	FILM, SOLUBLE	280 mg	VAGINAL	OTC MONOGRAPH NOT FINAL	14 sections
VCF CONTRACEPTIVE	HUMAN OTC DRUG LABEL	1	52925-312	AEROSOL, FOAM	125 mg	VAGINAL	OTC MONOGRAPH NOT FINAL	14 sections
VCF CONTRACEPTIVE PRE-FILLED APPLICATORS	HUMAN OTC DRUG LABEL	1	52925-512	GEL, METERED	4 g	VAGINAL	OTC MONOGRAPH NOT FINAL	13 sections
VCF CONTRACEPTIVE PRE-FILLED APPLICATORS	HUMAN OTC DRUG LABEL	1	52925-512	GEL, METERED	4 g	VAGINAL	OTC MONOGRAPH NOT FINAL	13 sections