nonoxinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5107 26027-38-3

Description:

MoleculeDescription

Synonyms:

  • nonoxinol
  • nonoxynol 9
  • nonoxynol-9
  • nonoxynol 4,9,15,30
Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.
  • Molecular weight:
  • Formula: C15H24O(C2H4O)n
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 10, 1963 FDA PERSONAL PRODS

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:38828 non-ionic surfactant
CHEBI has role CHEBI:49323 contraceptive drugs
MeSH PA D000988 Antispermatogenic Agents
MeSH PA D003270 Contraceptive Agents
MeSH PA D003271 Contraceptive Agents, Female
MeSH PA D009676 Noxae
MeSH PA D012102 Reproductive Control Agents
MeSH PA D013089 Spermatocidal Agents
MeSH PA D013501 Surface-Active Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Contraception indication 13197004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018924 VANDF
4021065 VANDF
C0068943 UMLSCUI
CHEBI:53775 CHEBI
CHEMBL2108472 ChEMBL_ID
7700 PUBCHEM_CID
CHEMBL1410 ChEMBL_ID
48Q180SH9T UNII
DB06804 DRUGBANK_ID
53750 RXNORM
5185 MMSL
326454008 SNOMEDCT_US
397179004 SNOMEDCT_US
D017137 MESH_DESCRIPTOR_UI
001328 NDDF
007492 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ConceptrolOptions HUMAN OTC DRUG LABEL 1 34362-0300 GEL 4 g VAGINAL OTC monograph not final 9 sections
Gynol IIExtra Strength HUMAN OTC DRUG LABEL 1 34362-0302 GEL 3 g VAGINAL OTC monograph not final 9 sections
Today Vaginal Contraceptive HUMAN OTC DRUG LABEL 1 44376-100 SPONGE 1000 mg VAGINAL NDA 16 sections
VCF CONTRACEPTIVE HUMAN OTC DRUG LABEL 1 52925-112 FILM, SOLUBLE 280 mg VAGINAL OTC MONOGRAPH NOT FINAL 14 sections
VCF CONTRACEPTIVE HUMAN OTC DRUG LABEL 1 52925-312 AEROSOL, FOAM 125 mg VAGINAL OTC MONOGRAPH NOT FINAL 14 sections
VCF CONTRACEPTIVE PRE-FILLED APPLICATORS HUMAN OTC DRUG LABEL 1 52925-512 GEL, METERED 4 g VAGINAL OTC MONOGRAPH NOT FINAL 13 sections