obiltoxaximab 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
chimeric origin 5094 1351337-07-9

Description:

MoleculeDescription

Synonyms:

  • obiltoxaximab
  • anthim
  • ETI-204
A monoclonal antibody that neutralizes toxins produced by BACILLUS ANTHRACIS. It is used to treat inhalational ANTHRAX.
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
March 18, 2016 FDA ELUSYS THERAPEUTICS INC

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J06BC04 ANTIINFECTIVES FOR SYSTEMIC USE
IMMUNE SERA AND IMMUNOGLOBULINS
IMMUNOGLOBULINS
Antibacterial monoclonal antibodies
FDA MoA N0000192702 Anthrax Protective Antigen-directed Antibody Interactions
FDA EPC N0000192703 Anthrax Protective Antigen-directed Antibody

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Inhalational anthrax indication 11389007




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Protective antigen Secreted ANTIBODY BINDING Kd 9.48 DRUG LABEL DRUG LABEL

External reference:

IDSource
29Z5DNL48C UNII
D10776 KEGG_DRUG
C4224790 UMLSCUI
CHEMBL3544926 ChEMBL_ID
DB05336 DRUGBANK_ID
9825 INN_ID
C000611266 MESH_SUPPLEMENTAL_RECORD_UI
1746906 RXNORM
31579 MMSL
724038005 SNOMEDCT_US
763558008 SNOMEDCT_US
016999 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Anthim HUMAN PRESCRIPTION DRUG LABEL 1 69604-204 SOLUTION 100 mg INTRAVENOUS BLA 28 sections