obiltoxaximab 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
chimeric origin	5094	1351337-07-9

Description:

Molecule

Description

Synonyms:

obiltoxaximab
anthim
ETI-204

A monoclonal antibody that neutralizes toxins produced by BACILLUS ANTHRACIS. It is used to treat inhalational ANTHRAX.

Molecular weight:
Formula:
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
March 18, 2016	FDA	ELUSYS THERAPEUTICS INC

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	J06BC04	ANTIINFECTIVES FOR SYSTEMIC USE IMMUNE SERA AND IMMUNOGLOBULINS IMMUNOGLOBULINS Antibacterial monoclonal antibodies
FDA MoA	N0000192702	Anthrax Protective Antigen-directed Antibody Interactions
FDA EPC	N0000192703	Anthrax Protective Antigen-directed Antibody

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Inhalational anthrax	indication	11389007

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Protective antigen	Secreted		PAG_BACAN	ANTIBODY BINDING	Kd	9.48		DRUG LABEL	DRUG LABEL

External reference:

ID	Source
29Z5DNL48C	UNII
D10776	KEGG_DRUG
C4224790	UMLSCUI
CHEMBL3544926	ChEMBL_ID
DB05336	DRUGBANK_ID
9825	INN_ID
C000611266	MESH_SUPPLEMENTAL_RECORD_UI
1746906	RXNORM
31579	MMSL
016999	NDDF
724038005	SNOMEDCT_US
763558008	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Anthim	HUMAN PRESCRIPTION DRUG LABEL	1	69604-204	SOLUTION	100 mg	INTRAVENOUS	BLA	28 sections
Anthim	HUMAN PRESCRIPTION DRUG LABEL	1	69604-204	SOLUTION	100 mg	INTRAVENOUS	BLA	28 sections
Anthim	HUMAN PRESCRIPTION DRUG LABEL	1	69604-204	SOLUTION	100 mg	INTRAVENOUS	BLA	28 sections