arterolane 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antimalarial agents, artemisinin related compounds 5090 664338-39-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • arterolane
  • arterolane maleate
  • OZ277
  • OZ 277
a trioxolane with antimalarial activity
  • Molecular weight: 378.51
  • Formula: C21H34N2O4
  • CLOGP: 2.44
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 82.81
  • ALOGS: -4.24
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
March 9, 2012 CDSCO (INDIA)

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01BX02 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
ANTIMALARIALS
Other antimalarials
CHEBI has role CHEBI:38068 antimalarials
CHEBI has role CHEBI:64915 antiplasmodial agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Falciparum malaria indication 62676009 DOID:14067




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.38 acidic
pKa2 9.54 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
3N1TN351VB UNII
959520-73-1 SECONDARY_CAS_RN
C2977963 UMLSCUI
CHEBI:136054 CHEBI
CHEMBL570680 ChEMBL_ID
10475633 PUBCHEM_CID
CHEMBL221773 ChEMBL_ID
CHEMBL404431 ChEMBL_ID
8663 INN_ID
C489136 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None