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carisoprodol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 509 | 78-44-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 1.40 | g | O |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| MRTD (Maximum Recommended Therapeutic Daily Dose) | 76.83 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Hosey CM, Chan R, Benet LZ |
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| azlogd74 | LogD at pH 7.4 | 2.203 | High | 1 | |
| caco2-efflux | Caco-2 efflux ratio (BA/AB) | 1.614 | High | 1 | |
| caco2-intrinsic-papp | Caco-2 intrinsic apparent permeability | 54.325 | 10^-6 cm/s | High | 1 |
| dh-clint | Dog hepatocyte intrinsic clearance | 6.383 | uL/min/10^6 cells | High | 1 |
| dppb | Dog plasma protein binding (% unbound) | 53.050 | % | High | 1 |
| fcs-ppb | Fetal calf serum protein binding (% unbound) | 64.320 | % | High | 1 |
| herg | hERG pIC50 | 4.400 | pIC50 | High | 1 |
| hh-clint | Human hepatocyte intrinsic clearance | 3.062 | uL/min/10^6 cells | High | 1 |
| hlm-clint | Human liver microsomal intrinsic clearance | 18.880 | uL/min/mg protein | High | 1 |
| hppb | Human plasma protein binding (% unbound) | 51.670 | % | High | 1 |
| kinase-safety-class | ACVR2A,ACVR2B,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,MAP2K6,MAP3K21,MAP3K7,MAPK7,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PLK1,PLK2,PLK3,PLK4,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK | 48 | |||
| kinase-selectivity-class | AXL,BRAF,CAMK2D,CDK1,CDK16,CDK4,CDK9,DDR1,DYRK1A,EPHB4,FLT3,GRK2,IRAK1,IRAK3,LRRK2,MAP3K21,PDK1,STK33,TEK | 19 | |||
| mdck-mdr1-efflux | MDCK-MDR1 efflux ratio | 3.524 | High | 1 | |
| mh-clint | Mouse hepatocyte intrinsic clearance | 28.576 | High | 1 | |
| mppb | Mouse plasma protein binding (% unbound) | 50.120 | High | 1 | |
| nih-mdck-mdr1-efflux | NIH MDCK-MDR1 efflux ratio | 9.183 | High | 1 | |
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 | |||
| pppb | Pig plasma protein binding (% unbound) | 66.610 | % | High | 1 |
| rh-clint | Rat hepatocyte intrinsic clearance | 27.669 | uL/min/10^6 cells | High | 1 |
| rh-fuinc | Rat hepatocyte fraction unbound in incubation | 90.810 | % | High | 1 |
| rppb | Rat plasma protein binding (% unbound) | 44.040 | % | High | 1 |
| solubility-dd | Solubility at pH 7.4 in DMSO | 891.251 | uM | High | 1 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| April 9, 1959 | FDA | MEDA PHARMS |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Completed suicide | 1667.82 | 14.26 | 793 | 22907 | 144265 | 90460482 |
| Respiratory arrest | 712.39 | 14.26 | 283 | 23417 | 33028 | 90571719 |
| Toxicity to various agents | 582.13 | 14.26 | 529 | 23171 | 287317 | 90317430 |
| Cardiac arrest | 441.74 | 14.26 | 298 | 23402 | 104637 | 90500110 |
| Cardio-respiratory arrest | 303.63 | 14.26 | 195 | 23505 | 62945 | 90541802 |
| Drug abuse | 274.67 | 14.26 | 203 | 23497 | 82144 | 90522603 |
| Poisoning | 167.18 | 14.26 | 81 | 23619 | 15136 | 90589611 |
| Overdose | 149.68 | 14.26 | 195 | 23505 | 157514 | 90447233 |
| Drug abuser | 122.36 | 14.26 | 40 | 23660 | 2650 | 90602097 |
| Drug dependence | 117.72 | 14.26 | 81 | 23619 | 29246 | 90575501 |
| Drug withdrawal syndrome | 116.87 | 14.26 | 80 | 23620 | 28643 | 90576104 |
| Intentional product misuse | 111.30 | 14.26 | 127 | 23573 | 89477 | 90515270 |
| Accidental overdose | 108.58 | 14.26 | 76 | 23624 | 28197 | 90576550 |
| Off label use | 104.07 | 14.26 | 82 | 23618 | 1102170 | 89502577 |
| Unresponsive to stimuli | 96.68 | 14.26 | 80 | 23620 | 38041 | 90566706 |
| Exposure via ingestion | 91.15 | 14.26 | 32 | 23668 | 2635 | 90602112 |
| Coma | 83.58 | 14.26 | 99 | 23601 | 72533 | 90532214 |
| Maternal exposure during pregnancy | 81.00 | 14.26 | 3 | 23697 | 360060 | 90244687 |
| Dependence | 78.80 | 14.26 | 27 | 23673 | 2068 | 90602679 |
| Infusion related reaction | 75.31 | 14.26 | 10 | 23690 | 416770 | 90187977 |
| Contraindicated product administered | 70.87 | 14.26 | 3 | 23697 | 320136 | 90284611 |
| Depression | 68.53 | 14.26 | 203 | 23497 | 300398 | 90304349 |
| Systemic lupus erythematosus | 60.11 | 14.26 | 11 | 23689 | 361885 | 90242862 |
| Urinary bladder rupture | 58.70 | 14.26 | 13 | 23687 | 188 | 90604559 |
| Wound | 57.86 | 14.26 | 6 | 23694 | 302974 | 90301773 |
| Narcotic bowel syndrome | 56.96 | 14.26 | 12 | 23688 | 135 | 90604612 |
| Drug screen positive | 56.91 | 14.26 | 25 | 23675 | 3732 | 90601015 |
| Anxiety | 56.70 | 14.26 | 194 | 23506 | 309578 | 90295169 |
| Drug intolerance | 55.20 | 14.26 | 24 | 23676 | 447567 | 90157180 |
| Lethargy | 55.09 | 14.26 | 75 | 23625 | 63064 | 90541683 |
| Accidental death | 52.95 | 14.26 | 20 | 23680 | 2028 | 90602719 |
| Intentional overdose | 52.90 | 14.26 | 91 | 23609 | 93743 | 90511004 |
| Discomfort | 48.54 | 14.26 | 7 | 23693 | 274328 | 90330419 |
| Seizure | 46.73 | 14.26 | 115 | 23585 | 152514 | 90452233 |
| Product use in unapproved indication | 46.51 | 14.26 | 15 | 23685 | 336221 | 90268526 |
| Joint swelling | 45.36 | 14.26 | 39 | 23661 | 503261 | 90101486 |
| Hepatic enzyme increased | 45.01 | 14.26 | 19 | 23681 | 360717 | 90244030 |
| Feeling abnormal | 42.97 | 14.26 | 118 | 23582 | 167117 | 90437630 |
| Lower respiratory tract infection | 40.79 | 14.26 | 8 | 23692 | 250651 | 90354096 |
| Emotional distress | 40.56 | 14.26 | 49 | 23651 | 36613 | 90568134 |
| Alopecia | 40.35 | 14.26 | 42 | 23658 | 495029 | 90109718 |
| Helicobacter infection | 39.64 | 14.26 | 6 | 23694 | 226844 | 90377903 |
| Abdominal discomfort | 37.22 | 14.26 | 42 | 23658 | 477286 | 90127461 |
| Intervertebral disc protrusion | 36.22 | 14.26 | 40 | 23660 | 27156 | 90577591 |
| Rash | 35.11 | 14.26 | 100 | 23600 | 796000 | 89808747 |
| Loss of consciousness | 35.08 | 14.26 | 98 | 23602 | 140140 | 90464607 |
| Stomatitis | 35.01 | 14.26 | 14 | 23686 | 274684 | 90330063 |
| Soft tissue haemorrhage | 34.25 | 14.26 | 9 | 23691 | 275 | 90604472 |
| Somnolence | 33.97 | 14.26 | 126 | 23574 | 208958 | 90395789 |
| Liver injury | 33.54 | 14.26 | 3 | 23697 | 170564 | 90434183 |
| Muscle injury | 32.45 | 14.26 | 4 | 23696 | 176650 | 90428097 |
| Death | 32.25 | 14.26 | 217 | 23483 | 456334 | 90148413 |
| Insomnia | 32.19 | 14.26 | 172 | 23528 | 333302 | 90271445 |
| Product use issue | 31.65 | 14.26 | 24 | 23676 | 329895 | 90274852 |
| Purpura senile | 31.46 | 14.26 | 10 | 23690 | 605 | 90604142 |
| Impaired healing | 31.41 | 14.26 | 11 | 23689 | 234188 | 90370559 |
| Blister | 30.89 | 14.26 | 14 | 23686 | 254984 | 90349763 |
| Back pain | 30.88 | 14.26 | 164 | 23536 | 317011 | 90287736 |
| Spinal epidural haematoma | 30.81 | 14.26 | 12 | 23688 | 1322 | 90603425 |
| Suspected suicide | 30.53 | 14.26 | 23 | 23677 | 9545 | 90595202 |
| Infection | 30.30 | 14.26 | 30 | 23670 | 362064 | 90242683 |
| Pulmonary congestion | 30.15 | 14.26 | 31 | 23669 | 19402 | 90585345 |
| Arthropathy | 29.90 | 14.26 | 31 | 23669 | 366211 | 90238536 |
| Ill-defined disorder | 29.87 | 14.26 | 6 | 23694 | 184885 | 90419862 |
| Suicidal ideation | 29.66 | 14.26 | 62 | 23638 | 73793 | 90530954 |
| Peripheral swelling | 28.39 | 14.26 | 40 | 23660 | 413066 | 90191681 |
| Tarsal tunnel syndrome | 27.95 | 14.26 | 9 | 23691 | 568 | 90604179 |
| Quadriplegia | 27.94 | 14.26 | 13 | 23687 | 2218 | 90602529 |
| Neutropenia | 27.79 | 14.26 | 12 | 23688 | 224892 | 90379855 |
| C-reactive protein increased | 27.08 | 14.26 | 7 | 23693 | 181382 | 90423365 |
| Coronary artery disease | 26.43 | 14.26 | 38 | 23662 | 33585 | 90571162 |
| Crying | 26.31 | 14.26 | 33 | 23667 | 25612 | 90579135 |
| Intervertebral disc degeneration | 25.80 | 14.26 | 27 | 23673 | 17247 | 90587500 |
| Mobility decreased | 25.67 | 14.26 | 17 | 23683 | 250717 | 90354030 |
| General physical health deterioration | 24.78 | 14.26 | 34 | 23666 | 355081 | 90249666 |
| Exposure during pregnancy | 24.63 | 14.26 | 16 | 23684 | 238394 | 90366353 |
| Tremor | 24.61 | 14.26 | 92 | 23608 | 153081 | 90451666 |
| Psoriatic arthropathy | 24.03 | 14.26 | 15 | 23685 | 228320 | 90376427 |
| Hyperhidrosis | 23.70 | 14.26 | 84 | 23616 | 136221 | 90468526 |
| Fall | 23.43 | 14.26 | 210 | 23490 | 481600 | 90123147 |
| Inadequate analgesia | 23.41 | 14.26 | 13 | 23687 | 3211 | 90601536 |
| Mydriasis | 23.39 | 14.26 | 24 | 23676 | 14988 | 90589759 |
| Type 2 diabetes mellitus | 23.33 | 14.26 | 12 | 23688 | 203232 | 90401515 |
| Blood pH decreased | 23.32 | 14.26 | 12 | 23688 | 2546 | 90602201 |
| Suicide attempt | 23.26 | 14.26 | 57 | 23643 | 75342 | 90529405 |
| Distributive shock | 22.68 | 14.26 | 13 | 23687 | 3411 | 90601336 |
| Respiratory depression | 22.65 | 14.26 | 24 | 23676 | 15551 | 90589196 |
| Hypersensitivity | 22.37 | 14.26 | 54 | 23646 | 454623 | 90150124 |
| Febrile neutropenia | 21.99 | 14.26 | 7 | 23693 | 158342 | 90446405 |
| Wheezing | 21.96 | 14.26 | 18 | 23682 | 238062 | 90366685 |
| Product complaint | 21.79 | 14.26 | 22 | 23678 | 13478 | 90591269 |
| Thrombocytopenia | 21.57 | 14.26 | 14 | 23686 | 208711 | 90396036 |
| Resorption bone increased | 21.39 | 14.26 | 9 | 23691 | 1210 | 90603537 |
| Pleural adhesion | 21.34 | 14.26 | 5 | 23695 | 94 | 90604653 |
| Nasopharyngitis | 21.11 | 14.26 | 47 | 23653 | 407057 | 90197690 |
| Mental status changes | 20.93 | 14.26 | 40 | 23660 | 44639 | 90560108 |
| Drowning | 20.74 | 14.26 | 7 | 23693 | 512 | 90604235 |
| Irritability | 20.63 | 14.26 | 35 | 23665 | 35627 | 90569120 |
| Thinking abnormal | 20.57 | 14.26 | 20 | 23680 | 11712 | 90593035 |
| Nervousness | 20.47 | 14.26 | 34 | 23666 | 34022 | 90570725 |
| Impaired driving ability | 20.07 | 14.26 | 14 | 23686 | 5159 | 90599588 |
| Arteriosclerosis | 19.97 | 14.26 | 19 | 23681 | 10834 | 90593913 |
| Hyperlipidaemia | 19.65 | 14.26 | 27 | 23673 | 22889 | 90581858 |
| Drug ineffective | 19.35 | 14.26 | 251 | 23449 | 1384047 | 89220700 |
| Vestibular disorder | 19.32 | 14.26 | 9 | 23691 | 1540 | 90603207 |
| Musculoskeletal stiffness | 19.10 | 14.26 | 30 | 23670 | 296502 | 90308245 |
| Therapeutic product effect incomplete | 18.72 | 14.26 | 14 | 23686 | 193882 | 90410865 |
| Stress | 18.52 | 14.26 | 55 | 23645 | 81340 | 90523407 |
| Withdrawal syndrome | 18.50 | 14.26 | 26 | 23674 | 22498 | 90582249 |
| Inflammation | 18.42 | 14.26 | 12 | 23688 | 178580 | 90426167 |
| Progressive multiple sclerosis | 17.64 | 14.26 | 8 | 23692 | 1286 | 90603461 |
| Abnormal dreams | 17.54 | 14.26 | 18 | 23682 | 11239 | 90593508 |
| Migraine | 17.53 | 14.26 | 97 | 23603 | 190295 | 90414452 |
| Pain | 17.48 | 14.26 | 361 | 23339 | 995980 | 89608767 |
| Gastrointestinal disorder | 17.47 | 14.26 | 25 | 23675 | 256662 | 90348085 |
| Pancytopenia | 17.27 | 14.26 | 5 | 23695 | 120258 | 90484489 |
| Substance abuse | 17.26 | 14.26 | 13 | 23687 | 5393 | 90599354 |
| Pneumonia aspiration | 17.18 | 14.26 | 35 | 23665 | 40905 | 90563842 |
| Therapeutic product effect decreased | 17.02 | 14.26 | 29 | 23671 | 277542 | 90327205 |
| Bronchitis | 16.91 | 14.26 | 82 | 23618 | 152845 | 90451902 |
| Pre-existing condition improved | 16.77 | 14.26 | 16 | 23684 | 9153 | 90595594 |
| Multiple sclerosis relapse | 16.62 | 14.26 | 40 | 23660 | 52265 | 90552482 |
| Condition aggravated | 16.48 | 14.26 | 90 | 23610 | 595455 | 90009292 |
| Facet joint syndrome | 16.29 | 14.26 | 3 | 23697 | 98386 | 90506361 |
| Pulmonary oedema | 16.12 | 14.26 | 44 | 23656 | 62036 | 90542711 |
| Chest pain | 15.86 | 14.26 | 140 | 23560 | 319505 | 90285242 |
| Joint range of motion decreased | 15.57 | 14.26 | 8 | 23692 | 135635 | 90469112 |
| Lung disorder | 15.55 | 14.26 | 10 | 23690 | 149873 | 90454874 |
| Deep vein thrombosis | 15.53 | 14.26 | 56 | 23644 | 91564 | 90513183 |
| Blood chloride decreased | 15.47 | 14.26 | 13 | 23687 | 6306 | 90598441 |
| Spinal operation | 15.34 | 14.26 | 16 | 23684 | 10180 | 90594567 |
| Cervicobrachial syndrome | 15.25 | 14.26 | 7 | 23693 | 1158 | 90603589 |
| Pupillary reflex impaired | 15.11 | 14.26 | 9 | 23691 | 2536 | 90602211 |
| Grip strength decreased | 14.95 | 14.26 | 3 | 23697 | 92573 | 90512174 |
| Hyperreflexia | 14.88 | 14.26 | 13 | 23687 | 6644 | 90598103 |
| Fear | 14.88 | 14.26 | 20 | 23680 | 16602 | 90588145 |
| Multiple injuries | 14.87 | 14.26 | 8 | 23692 | 1857 | 90602890 |
| Pulmonary fibrosis | 14.49 | 14.26 | 5 | 23695 | 107498 | 90497249 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Respiratory arrest | 479.39 | 18.22 | 200 | 10290 | 28224 | 42582621 |
| Completed suicide | 452.84 | 18.22 | 286 | 10204 | 96179 | 42514666 |
| Toxicity to various agents | 270.91 | 18.22 | 306 | 10184 | 228830 | 42382015 |
| Cardiac arrest | 245.88 | 18.22 | 208 | 10282 | 109112 | 42501733 |
| Drug abuse | 196.69 | 18.22 | 180 | 10310 | 104591 | 42506254 |
| Overdose | 192.07 | 18.22 | 178 | 10312 | 105086 | 42505759 |
| Drug dependence | 176.54 | 18.22 | 102 | 10388 | 28992 | 42581853 |
| Drug abuser | 165.86 | 18.22 | 53 | 10437 | 3478 | 42607367 |
| Drug withdrawal syndrome | 159.21 | 18.22 | 86 | 10404 | 21463 | 42589382 |
| Cardio-respiratory arrest | 144.90 | 18.22 | 118 | 10372 | 58518 | 42552327 |
| Accidental overdose | 107.98 | 18.22 | 74 | 10416 | 28256 | 42582589 |
| Poisoning | 67.13 | 18.22 | 43 | 10447 | 14656 | 42596189 |
| Depression | 65.08 | 18.22 | 106 | 10384 | 111257 | 42499588 |
| Intentional product misuse | 59.95 | 18.22 | 75 | 10415 | 61825 | 42549020 |
| Off label use | 57.72 | 18.22 | 44 | 10446 | 638291 | 41972554 |
| Inadequate analgesia | 55.44 | 18.22 | 23 | 10467 | 3174 | 42607671 |
| Anxiety | 55.09 | 18.22 | 102 | 10388 | 118458 | 42492387 |
| Nervousness | 48.37 | 18.22 | 34 | 10456 | 13498 | 42597347 |
| Road traffic accident | 48.29 | 18.22 | 39 | 10451 | 19054 | 42591791 |
| Insomnia | 42.03 | 18.22 | 91 | 10399 | 118162 | 42492683 |
| Drug screen positive | 40.62 | 18.22 | 20 | 10470 | 4111 | 42606734 |
| Administration related reaction | 38.82 | 18.22 | 9 | 10481 | 172 | 42610673 |
| Suicidal ideation | 33.89 | 18.22 | 50 | 10440 | 48111 | 42562734 |
| Neutropenia | 32.76 | 18.22 | 5 | 10485 | 199426 | 42411419 |
| Exposure via ingestion | 32.57 | 18.22 | 14 | 10476 | 2108 | 42608737 |
| Hypoaesthesia | 32.54 | 18.22 | 61 | 10429 | 71402 | 42539443 |
| Back pain | 32.24 | 18.22 | 92 | 10398 | 141684 | 42469161 |
| Product use in unapproved indication | 31.76 | 18.22 | 4 | 10486 | 184452 | 42426393 |
| Febrile neutropenia | 29.72 | 18.22 | 5 | 10485 | 185698 | 42425147 |
| Emotional distress | 28.81 | 18.22 | 27 | 10463 | 16066 | 42594779 |
| Substance abuse | 26.43 | 18.22 | 20 | 10470 | 8885 | 42601960 |
| Acute kidney injury | 25.34 | 18.22 | 32 | 10458 | 367305 | 42243540 |
| Pain | 25.21 | 18.22 | 123 | 10367 | 244725 | 42366120 |
| Accidental death | 24.70 | 18.22 | 13 | 10477 | 3070 | 42607775 |
| Drug tolerance | 23.91 | 18.22 | 13 | 10477 | 3277 | 42607568 |
| Product complaint | 23.67 | 18.22 | 16 | 10474 | 5961 | 42604884 |
| Respiratory rate decreased | 22.41 | 18.22 | 12 | 10478 | 2933 | 42607912 |
| Coronary artery disease | 22.17 | 18.22 | 44 | 10446 | 53676 | 42557169 |
| Amnesia | 22.16 | 18.22 | 31 | 10459 | 28406 | 42582439 |
| Kussmaul respiration | 21.31 | 18.22 | 5 | 10485 | 101 | 42610744 |
| Unresponsive to stimuli | 21.22 | 18.22 | 32 | 10458 | 31371 | 42579474 |
| Back injury | 20.54 | 18.22 | 13 | 10477 | 4335 | 42606510 |
| Dependence | 20.23 | 18.22 | 9 | 10481 | 1471 | 42609374 |
| Pyrexia | 19.98 | 18.22 | 42 | 10448 | 394000 | 42216845 |
| Sinus tachycardia | 19.93 | 18.22 | 25 | 10465 | 20628 | 42590217 |
| Mental disorder due to a general medical condition | 19.72 | 18.22 | 5 | 10485 | 141 | 42610704 |
| Ventricular hypertrophy | 19.33 | 18.22 | 13 | 10477 | 4803 | 42606042 |
| Blood pH decreased | 19.30 | 18.22 | 10 | 10480 | 2288 | 42608557 |
| Myofascial pain syndrome | 19.27 | 18.22 | 6 | 10484 | 361 | 42610484 |
| Agitation | 18.95 | 18.22 | 46 | 10444 | 64268 | 42546577 |
| COVID-19 | 18.81 | 18.22 | 3 | 10487 | 115945 | 42494900 |
| Muscle spasms | 18.72 | 18.22 | 55 | 10435 | 85989 | 42524856 |
| Intervertebral disc protrusion | 18.72 | 18.22 | 18 | 10472 | 11054 | 42599791 |
| Injury | 18.40 | 18.22 | 25 | 10465 | 22291 | 42588554 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Completed suicide | 2458.05 | 13.68 | 1200 | 26672 | 241181 | 110320246 |
| Respiratory arrest | 1257.79 | 13.68 | 493 | 27379 | 57806 | 110503621 |
| Toxicity to various agents | 820.72 | 13.68 | 790 | 27082 | 479765 | 110081662 |
| Cardiac arrest | 748.54 | 13.68 | 517 | 27355 | 196236 | 110365191 |
| Cardio-respiratory arrest | 508.44 | 13.68 | 333 | 27539 | 115503 | 110445924 |
| Drug abuse | 469.18 | 13.68 | 375 | 27497 | 177036 | 110384391 |
| Overdose | 409.87 | 13.68 | 391 | 27481 | 233403 | 110328024 |
| Drug abuser | 280.24 | 13.68 | 88 | 27784 | 5321 | 110556106 |
| Drug dependence | 231.93 | 13.68 | 149 | 27723 | 49871 | 110511556 |
| Poisoning | 231.37 | 13.68 | 123 | 27749 | 28982 | 110532445 |
| Drug withdrawal syndrome | 223.96 | 13.68 | 132 | 27740 | 37922 | 110523505 |
| Intentional product misuse | 207.71 | 13.68 | 209 | 27663 | 132695 | 110428732 |
| Accidental overdose | 203.03 | 13.68 | 139 | 27733 | 51695 | 110509732 |
| Off label use | 156.13 | 13.68 | 93 | 27779 | 1500092 | 109061335 |
| Exposure via ingestion | 121.68 | 13.68 | 46 | 27826 | 4854 | 110556573 |
| Intentional overdose | 118.13 | 13.68 | 156 | 27716 | 132345 | 110429082 |
| Unresponsive to stimuli | 102.66 | 13.68 | 102 | 27770 | 63688 | 110497739 |
| Depression | 95.47 | 13.68 | 232 | 27640 | 317103 | 110244324 |
| Coma | 81.62 | 13.68 | 123 | 27749 | 117746 | 110443681 |
| Drug screen positive | 80.50 | 13.68 | 37 | 27835 | 6373 | 110555054 |
| Product use in unapproved indication | 74.05 | 13.68 | 12 | 27860 | 447365 | 110114062 |
| Accidental death | 72.73 | 13.68 | 32 | 27840 | 4977 | 110556450 |
| Anxiety | 72.40 | 13.68 | 221 | 27651 | 344857 | 110216570 |
| Dependence | 69.14 | 13.68 | 26 | 27846 | 2703 | 110558724 |
| Drug intolerance | 67.06 | 13.68 | 11 | 27861 | 406501 | 110154926 |
| Neutropenia | 59.89 | 13.68 | 11 | 27861 | 374609 | 110186818 |
| Synovitis | 56.75 | 13.68 | 3 | 27869 | 274089 | 110287338 |
| Inadequate analgesia | 56.62 | 13.68 | 27 | 27845 | 5050 | 110556377 |
| Emotional distress | 56.59 | 13.68 | 63 | 27809 | 44784 | 110516643 |
| Urinary bladder rupture | 55.67 | 13.68 | 12 | 27860 | 158 | 110561269 |
| Infusion related reaction | 55.22 | 13.68 | 14 | 27858 | 381148 | 110180279 |
| Lethargy | 51.53 | 13.68 | 88 | 27784 | 93488 | 110467939 |
| Coronary artery disease | 49.88 | 13.68 | 75 | 27797 | 71615 | 110489812 |
| Febrile neutropenia | 47.12 | 13.68 | 11 | 27861 | 316756 | 110244671 |
| Treatment failure | 46.84 | 13.68 | 7 | 27865 | 277227 | 110284200 |
| Systemic lupus erythematosus | 46.41 | 13.68 | 5 | 27867 | 254333 | 110307094 |
| Joint swelling | 45.02 | 13.68 | 28 | 27844 | 442817 | 110118610 |
| Death | 44.01 | 13.68 | 314 | 27558 | 698555 | 109862872 |
| Blood pH decreased | 43.61 | 13.68 | 22 | 27850 | 4647 | 110556780 |
| Nervousness | 43.48 | 13.68 | 50 | 27822 | 36801 | 110524626 |
| Suicidal ideation | 42.37 | 13.68 | 81 | 27791 | 93856 | 110467571 |
| Insomnia | 40.44 | 13.68 | 189 | 27683 | 360401 | 110201026 |
| Acute kidney injury | 39.49 | 13.68 | 62 | 27810 | 635368 | 109926059 |
| Wound | 39.41 | 13.68 | 6 | 27866 | 234431 | 110326996 |
| General physical health deterioration | 39.09 | 13.68 | 30 | 27842 | 425265 | 110136162 |
| C-reactive protein increased | 37.99 | 13.68 | 5 | 27867 | 217914 | 110343513 |
| Lower respiratory tract infection | 37.04 | 13.68 | 8 | 27864 | 243098 | 110318329 |
| Suicide attempt | 36.98 | 13.68 | 81 | 27791 | 103313 | 110458114 |
| Loss of consciousness | 36.78 | 13.68 | 121 | 27751 | 196185 | 110365242 |
| Substance abuse | 36.41 | 13.68 | 28 | 27844 | 12435 | 110548992 |
| Somnolence | 35.64 | 13.68 | 159 | 27713 | 297290 | 110264137 |
| Thrombocytopenia | 35.53 | 13.68 | 22 | 27850 | 348863 | 110212564 |
| Stomatitis | 35.33 | 13.68 | 12 | 27860 | 270230 | 110291197 |
| Narcotic bowel syndrome | 34.74 | 13.68 | 9 | 27863 | 270 | 110561157 |
| Hepatic enzyme increased | 34.42 | 13.68 | 19 | 27853 | 320873 | 110240554 |
| Back pain | 34.21 | 13.68 | 184 | 27688 | 370812 | 110190615 |
| Suspected suicide | 33.55 | 13.68 | 29 | 27843 | 15170 | 110546257 |
| Pyrexia | 33.05 | 13.68 | 116 | 27756 | 898149 | 109663278 |
| Tarsal tunnel syndrome | 32.95 | 13.68 | 10 | 27862 | 539 | 110560888 |
| Condition aggravated | 32.64 | 13.68 | 87 | 27785 | 734749 | 109826678 |
| Helicobacter infection | 32.12 | 13.68 | 4 | 27868 | 181873 | 110379554 |
| Seizure | 31.77 | 13.68 | 125 | 27747 | 221060 | 110340367 |
| Intervertebral disc protrusion | 31.70 | 13.68 | 37 | 27835 | 27661 | 110533766 |
| Sinus tachycardia | 31.59 | 13.68 | 47 | 27825 | 44446 | 110516981 |
| Intervertebral disc degeneration | 31.10 | 13.68 | 30 | 27842 | 18055 | 110543372 |
| Feeling abnormal | 30.87 | 13.68 | 108 | 27764 | 180603 | 110380824 |
| Infection | 30.27 | 13.68 | 28 | 27844 | 362172 | 110199255 |
| Tremor | 29.62 | 13.68 | 115 | 27757 | 202117 | 110359310 |
| Drug ineffective | 29.42 | 13.68 | 244 | 27628 | 1520296 | 109041131 |
| Irritability | 29.05 | 13.68 | 47 | 27825 | 47762 | 110513665 |
| Discomfort | 29.01 | 13.68 | 9 | 27863 | 214698 | 110346729 |
| Administration related reaction | 28.98 | 13.68 | 8 | 27864 | 307 | 110561120 |
| Alopecia | 28.40 | 13.68 | 30 | 27842 | 364723 | 110196704 |
| Pulmonary congestion | 28.40 | 13.68 | 37 | 27835 | 30929 | 110530498 |
| Spinal epidural haematoma | 28.25 | 13.68 | 12 | 27860 | 1713 | 110559714 |
| Myocardial infarction | 27.94 | 13.68 | 109 | 27763 | 191974 | 110369453 |
| Purpura senile | 27.71 | 13.68 | 9 | 27863 | 606 | 110560821 |
| Hyperlipidaemia | 27.09 | 13.68 | 39 | 27833 | 35809 | 110525618 |
| Arteriosclerosis | 26.56 | 13.68 | 32 | 27840 | 24735 | 110536692 |
| Pancytopenia | 26.22 | 13.68 | 10 | 27862 | 209603 | 110351824 |
| Soft tissue haemorrhage | 26.18 | 13.68 | 8 | 27864 | 441 | 110560986 |
| Product use issue | 26.15 | 13.68 | 24 | 27848 | 311671 | 110249756 |
| Product complaint | 25.59 | 13.68 | 24 | 27848 | 13948 | 110547479 |
| COVID-19 | 25.57 | 13.68 | 15 | 27857 | 245045 | 110316382 |
| Ventricular hypertrophy | 25.47 | 13.68 | 18 | 27854 | 7027 | 110554400 |
| Depressed level of consciousness | 25.47 | 13.68 | 74 | 27798 | 112204 | 110449223 |
| Hypersensitivity | 25.47 | 13.68 | 39 | 27833 | 403959 | 110157468 |
| Muscle injury | 25.10 | 13.68 | 3 | 27869 | 140804 | 110420623 |
| Respiratory rate decreased | 25 | 13.68 | 17 | 27855 | 6241 | 110555186 |
| Interstitial lung disease | 24.76 | 13.68 | 3 | 27869 | 139331 | 110422096 |
| Leukopenia | 24.57 | 13.68 | 4 | 27868 | 148787 | 110412640 |
| Peripheral swelling | 24.52 | 13.68 | 40 | 27832 | 403994 | 110157433 |
| Respiratory depression | 24.45 | 13.68 | 35 | 27837 | 31966 | 110529461 |
| Mydriasis | 24.37 | 13.68 | 29 | 27843 | 22128 | 110539299 |
| Mobility decreased | 24.12 | 13.68 | 15 | 27857 | 237407 | 110324020 |
| Pupillary reflex impaired | 23.80 | 13.68 | 14 | 27858 | 4001 | 110557426 |
| Psoriatic arthropathy | 23.61 | 13.68 | 10 | 27862 | 196751 | 110364676 |
| Chest pain | 23.56 | 13.68 | 169 | 27703 | 376206 | 110185221 |
| Renal impairment | 23.55 | 13.68 | 9 | 27863 | 188436 | 110372991 |
| Wheezing | 23.44 | 13.68 | 18 | 27854 | 255212 | 110306215 |
| Nasopharyngitis | 23.05 | 13.68 | 40 | 27832 | 394321 | 110167106 |
| Abdominal discomfort | 22.97 | 13.68 | 40 | 27832 | 393818 | 110167609 |
| Therapeutic product effect incomplete | 22.93 | 13.68 | 14 | 27858 | 223791 | 110337636 |
| Malignant neoplasm progression | 22.38 | 13.68 | 8 | 27864 | 174559 | 110386868 |
| Hyperhidrosis | 22.32 | 13.68 | 100 | 27772 | 187198 | 110374229 |
| Ill-defined disorder | 22.24 | 13.68 | 6 | 27866 | 156847 | 110404580 |
| Rash | 22.22 | 13.68 | 119 | 27753 | 820845 | 109740582 |
| Intervertebral disc disorder | 22.08 | 13.68 | 15 | 27857 | 5497 | 110555930 |
| Pain | 21.96 | 13.68 | 350 | 27522 | 954605 | 109606822 |
| Crying | 21.02 | 13.68 | 29 | 27843 | 25599 | 110535828 |
| Liver disorder | 21.02 | 13.68 | 5 | 27867 | 142238 | 110419189 |
| Quadriplegia | 20.88 | 13.68 | 13 | 27859 | 4114 | 110557313 |
| Drug-induced liver injury | 20.34 | 13.68 | 3 | 27869 | 120064 | 110441363 |
| Cardiac failure | 20.27 | 13.68 | 11 | 27861 | 187615 | 110373812 |
| Disease progression | 20.22 | 13.68 | 19 | 27853 | 244015 | 110317412 |
| Inflammation | 19.92 | 13.68 | 12 | 27860 | 193226 | 110368201 |
| Resorption bone increased | 19.72 | 13.68 | 9 | 27863 | 1525 | 110559902 |
| Blister | 19.68 | 13.68 | 17 | 27855 | 227359 | 110334068 |
| Agitation | 19.67 | 13.68 | 68 | 27804 | 112983 | 110448444 |
| Hypertensive heart disease | 19.59 | 13.68 | 13 | 27859 | 4583 | 110556844 |
| Impaired healing | 19.20 | 13.68 | 13 | 27859 | 196704 | 110364723 |
| Liver injury | 19.10 | 13.68 | 7 | 27865 | 150406 | 110411021 |
| Mental status changes | 19.05 | 13.68 | 52 | 27820 | 76070 | 110485357 |
| Asterixis | 18.69 | 13.68 | 11 | 27861 | 3147 | 110558280 |
| Dysarthria | 18.65 | 13.68 | 55 | 27817 | 84066 | 110477361 |
| Road traffic accident | 18.17 | 13.68 | 64 | 27808 | 107334 | 110454093 |
| Myofascial pain syndrome | 18.01 | 13.68 | 10 | 27862 | 2563 | 110558864 |
| Paranoia | 17.88 | 13.68 | 25 | 27847 | 22349 | 110539078 |
| Exposure during pregnancy | 17.82 | 13.68 | 10 | 27862 | 167414 | 110394013 |
| Progressive multiple sclerosis | 17.75 | 13.68 | 8 | 27864 | 1316 | 110560111 |
| Arteriosclerosis coronary artery | 17.07 | 13.68 | 26 | 27846 | 25092 | 110536335 |
| Cardiomegaly | 16.83 | 13.68 | 28 | 27844 | 29102 | 110532325 |
| Spinal osteoarthritis | 16.80 | 13.68 | 23 | 27849 | 20160 | 110541267 |
| Distributive shock | 16.67 | 13.68 | 13 | 27859 | 5891 | 110555536 |
| Gastrointestinal disorder | 16.58 | 13.68 | 22 | 27850 | 241930 | 110319497 |
| Multiple sclerosis relapse | 16.44 | 13.68 | 38 | 27834 | 50202 | 110511225 |
| Blood alcohol increased | 16.35 | 13.68 | 7 | 27865 | 1019 | 110560408 |
| Anger | 16.33 | 13.68 | 22 | 27850 | 18985 | 110542442 |
| Drug tolerance increased | 16.27 | 13.68 | 6 | 27866 | 591 | 110560836 |
| Neck injury | 16.08 | 13.68 | 10 | 27862 | 3158 | 110558269 |
| Lip dry | 15.85 | 13.68 | 3 | 27869 | 100080 | 110461347 |
| Impaired driving ability | 15.80 | 13.68 | 13 | 27859 | 6357 | 110555070 |
| Accidental poisoning | 15.61 | 13.68 | 9 | 27863 | 2478 | 110558949 |
| Blood chloride decreased | 15.45 | 13.68 | 15 | 27857 | 9100 | 110552327 |
| Vestibular disorder | 15.13 | 13.68 | 9 | 27863 | 2623 | 110558804 |
| Sepsis | 15.08 | 13.68 | 38 | 27834 | 327308 | 110234119 |
| Epistaxis | 15.05 | 13.68 | 7 | 27865 | 130365 | 110431062 |
| Tooth loss | 15.01 | 13.68 | 14 | 27858 | 8082 | 110553345 |
| Multiple injuries | 14.87 | 13.68 | 10 | 27862 | 3604 | 110557823 |
| Hyponatraemia | 14.70 | 13.68 | 20 | 27852 | 217633 | 110343794 |
| Generalised anxiety disorder | 14.68 | 13.68 | 9 | 27863 | 2770 | 110558657 |
| Bronchitis | 14.52 | 13.68 | 78 | 27794 | 156954 | 110404473 |
| Laryngeal pain | 14.41 | 13.68 | 12 | 27860 | 5963 | 110555464 |
| Fear | 14.36 | 13.68 | 23 | 27849 | 23170 | 110538257 |
| Pulmonary fibrosis | 14.28 | 13.68 | 4 | 27868 | 102038 | 110459389 |
| Withdrawal syndrome | 14.07 | 13.68 | 27 | 27845 | 31353 | 110530074 |
| Kussmaul respiration | 13.90 | 13.68 | 5 | 27867 | 459 | 110560968 |
| Miosis | 13.88 | 13.68 | 22 | 27850 | 21961 | 110539466 |
| Amnesia | 13.87 | 13.68 | 58 | 27814 | 105350 | 110456077 |
| Anaemia | 13.85 | 13.68 | 81 | 27791 | 547005 | 110014422 |
| Lung disorder | 13.79 | 13.68 | 15 | 27857 | 180032 | 110381395 |
| Drowning | 13.77 | 13.68 | 6 | 27866 | 911 | 110560516 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | M03BA02 | MUSCULO-SKELETAL SYSTEM MUSCLE RELAXANTS MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS Carbamic acid esters |
| ATC | M03BA52 | MUSCULO-SKELETAL SYSTEM MUSCLE RELAXANTS MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS Carbamic acid esters |
| ATC | M03BA72 | MUSCULO-SKELETAL SYSTEM MUSCLE RELAXANTS MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS Carbamic acid esters |
| CHEBI has role | CHEBI:35480 | analgesic |
| CHEBI has role | CHEBI:51371 | muscle relaxant |
| CHEBI has role | CHEBI:53784 | antispasmodic drug |
| MeSH PA | D009125 | Muscle Relaxants, Central |
| MeSH PA | D009465 | Neuromuscular Agents |
| FDA PE | N0000175730 | Centrally-mediated Muscle Relaxation |
| FDA EPC | N0000175737 | Muscle Relaxant |
Related Drugs by ATC class:
M03BA Carbamic acid esters 4 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Backache | indication | 161891005 | |
| Spasticity | indication | 221360009 | |
| Muscle Spasm with Pain | indication | ||
| Dependent drug abuse | contraindication | 6525002 | |
| Alcoholism | contraindication | 7200002 | |
| Peptic ulcer | contraindication | 13200003 | DOID:750 |
| Chronic disease of respiratory system | contraindication | 17097001 | |
| Mood swings | contraindication | 18963009 | |
| Lowered convulsive threshold | contraindication | 19260006 | |
| Inflammatory bowel disease | contraindication | 24526004 | DOID:0050589 |
| Alcohol intoxication | contraindication | 25702006 | |
| Disorder of gallbladder | contraindication | 39621005 | DOID:0060262 |
| Gastrointestinal ulcer | contraindication | 40845000 | |
| Hypothyroidism | contraindication | 40930008 | DOID:1459 |
| Conduction disorder of the heart | contraindication | 44808001 | |
| Low blood pressure | contraindication | 45007003 | |
| Bradycardia | contraindication | 48867003 | |
| Vitamin K deficiency | contraindication | 52675005 | DOID:11249 |
| Nasal polyp | contraindication | 52756005 | |
| Acute nephropathy | contraindication | 58574008 | |
| Drug AND/OR toxin-induced diarrhea | contraindication | 65979008 | |
| Substance abuse | contraindication | 66214007 | |
| Benign intracranial hypertension | contraindication | 68267002 | DOID:11459 |
| Sedation | contraindication | 72641008 | |
| Factor II deficiency | contraindication | 73975000 | |
| Reye's syndrome | contraindication | 74351001 | DOID:14525 |
| Gastrointestinal hemorrhage | contraindication | 74474003 | |
| Urethral stricture | contraindication | 76618002 | |
| Thrombotic thrombocytopenic purpura | contraindication | 78129009 | DOID:10772 |
| Decreased respiratory function | contraindication | 80954004 | |
| Injury of head | contraindication | 82271004 | |
| Epilepsy | contraindication | 84757009 | DOID:1826 |
| Gout | contraindication | 90560007 | DOID:13189 |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Hemophilia | contraindication | 90935002 | |
| Anemia due to enzyme deficiency | contraindication | 111577008 | |
| Acute abdominal pain | contraindication | 116290004 | |
| Procedure on urinary system | contraindication | 118677009 | |
| von Willebrand disorder | contraindication | 128105004 | DOID:12531 |
| Acute intermittent porphyria | contraindication | 234422006 | DOID:3890 |
| Disease of liver | contraindication | 235856003 | DOID:409 |
| Benign prostatic hyperplasia | contraindication | 266569009 | |
| Anemia | contraindication | 271737000 | DOID:2355 |
| Pregnancy, function | contraindication | 289908002 | |
| Lesion of brain | contraindication | 301766008 | |
| Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
| Primary adrenocortical insufficiency | contraindication | 373662000 | |
| Operation on gastrointestinal tract | contraindication | 386621005 | |
| Pseudomembranous enterocolitis | contraindication | 397683000 | |
| Breastfeeding (mother) | contraindication | 413712001 | |
| Central nervous system depression | contraindication | 418072004 | |
| Ultrarapid metabolizer due to cytochrome p450 CYP2D6 variant | contraindication | 422681000 | |
| Poor metabolizer due to cytochrome p450 CYP2C19 variant | contraindication | 424500005 | |
| Dysfunction of sphincter of Oddi | contraindication | 430887001 | |
| Acute erosive gastritis | contraindication | 444926003 | |
| Acute exacerbation of asthma | contraindication | 708038006 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4018454 | VUID |
| N0000146778 | NUI |
| D00768 | KEGG_DRUG |
| 2101 | RXNORM |
| C0007248 | UMLSCUI |
| CHEBI:3419 | CHEBI |
| CHEMBL1233 | ChEMBL_ID |
| DB00395 | DRUGBANK_ID |
| D002328 | MESH_DESCRIPTOR_UI |
| 2576 | PUBCHEM_CID |
| 7610 | IUPHAR_LIGAND_ID |
| 902 | INN_ID |
| 21925K482H | UNII |
| 4359 | MMSL |
| 747 | MMSL |
| d00960 | MMSL |
| 25076002 | SNOMEDCT_US |
| 387133006 | SNOMEDCT_US |
| 4018454 | VANDF |
| 001672 | NDDF |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Soma | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0037-2001 | TABLET | 350 mg | ORAL | NDA | 31 sections |
| Soma | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0037-2250 | TABLET | 250 mg | ORAL | NDA | 31 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-033 | TABLET | 350 mg | ORAL | ANDA | 28 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-088 | TABLET | 350 mg | ORAL | ANDA | 29 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10544-132 | TABLET | 350 mg | ORAL | ANDA | 27 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 12634-437 | TABLET | 350 mg | ORAL | ANDA | 32 sections |
| carisoprodol | Human Prescription Drug Label | 1 | 16571-780 | TABLET | 250 mg | ORAL | ANDA | 29 sections |
| carisoprodol | Human Prescription Drug Label | 1 | 16571-781 | TABLET | 350 mg | ORAL | ANDA | 29 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-039 | TABLET | 350 mg | ORAL | ANDA | 27 sections |
| SOMA | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-755 | TABLET | 250 mg | ORAL | NDA | 29 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL WITH HIGHLIGHTS | 1 | 21695-021 | TABLET | 350 mg | ORAL | ANDA | 29 sections |
| Carisoprodol and Aspirin | HUMAN PRESCRIPTION DRUG LABEL | 2 | 21695-570 | TABLET | 200 mg | ORAL | ANDA | 19 sections |
| Soma | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-606 | TABLET | 250 mg | ORAL | NDA | 29 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29033-207 | TABLET | 250 mg | ORAL | ANDA | 30 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29033-214 | TABLET | 350 mg | ORAL | ANDA | 30 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 33261-387 | TABLET | 350 mg | ORAL | ANDA | 28 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 33358-064 | TABLET | 350 mg | ORAL | ANDA | 29 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42543-700 | TABLET | 350 mg | ORAL | ANDA | 30 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42549-503 | TABLET | 350 mg | ORAL | ANDA | 27 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43353-102 | TABLET | 350 mg | ORAL | ANDA | 31 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45865-233 | TABLET | 350 mg | ORAL | ANDA | 26 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 45865-984 | TABLET | 350 mg | ORAL | ANDA | 30 sections |
| Carisoprodol | Human Prescription Drug Label | 1 | 50090-0280 | TABLET | 350 mg | ORAL | ANDA | 30 sections |
| Carisoprodol | Human Prescription Drug Label | 1 | 50090-0281 | TABLET | 350 mg | ORAL | ANDA | 30 sections |
| CARISOPRODOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-3048 | TABLET | 350 mg | ORAL | ANDA | 32 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-3232 | TABLET | 350 mg | ORAL | ANDA | 33 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4261 | TABLET | 350 mg | ORAL | ANDA | 27 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4263 | TABLET | 350 mg | ORAL | ANDA | 27 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4744 | TABLET | 350 mg | ORAL | ANDA | 31 sections |
| Carisoprodol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4746 | TABLET | 350 mg | ORAL | ANDA | 31 sections |