sodium iodide (131I) 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
radiopharmaceuticals, iodine-contained	5038	7790-26-3

Description:

Molecule

Description

Synonyms:

sodium iodide (131I)
sodium iodide I-131
iodotope
sodium iodide I 131

Molecular weight: 153.90
Formula: INa
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
May 2, 1957	FDA	BRACCO

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Parathyroid tumour benign	174.54	70.60	24	505	729	63487764
Hypothyroidism	136.56	70.60	37	492	42595	63445898
Endocrine ophthalmopathy	111.60	70.60	16	513	655	63487838
Sialoadenitis	104.11	70.60	17	512	1655	63486838
Dacryostenosis acquired	97.11	70.60	14	515	595	63487898
Acute leukaemia	81.12	70.60	13	516	1121	63487372
Abortion spontaneous	75.60	70.60	24	505	47171	63441322

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Hypothyroidism	334.40	64.40	79	606	52313	79691390
Parathyroid tumour benign	221.41	64.40	30	655	789	79742914
Endocrine ophthalmopathy	191.16	64.40	26	659	702	79743001
Dacryostenosis acquired	147.24	64.40	20	665	532	79743171
Acute leukaemia	88.97	64.40	15	670	1711	79741992
Treatment failure	72.00	64.40	33	652	170453	79573250

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	V09FX03	VARIOUS DIAGNOSTIC RADIOPHARMACEUTICALS THYROID Various thyroid diagnostic radiopharmaceuticals
ATC	V10XA01	VARIOUS THERAPEUTIC RADIOPHARMACEUTICALS OTHER THERAPEUTIC RADIOPHARMACEUTICALS Iodine (131I) compounds

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hyperthyroidism	indication	34486009	DOID:7998
Carcinoma of thyroid	indication	448216007

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D02259	KEGG_DRUG
4017585	VUID
N0000145966	NUI
4017585	VANDF
C0304982	UMLSCUI
CHEMBL1201084	ChEMBL_ID
71368	PUBCHEM_CID
91535	RXNORM
1798	MMSL
20994	MMSL
83206	MMSL
d00661	MMSL
007948	NDDF
111160004	SNOMEDCT_US
783854008	SNOMEDCT_US
279	INN_ID
29VCO8ACHH	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
I 131 Mini	HUMAN PRESCRIPTION DRUG LABEL	1	51808-119	CAPSULE	500 mCi	ORAL	Unapproved drug other	6 sections
Sodium Iodide I 131 Diagnostic	HUMAN PRESCRIPTION DRUG LABEL	1	65174-461	CAPSULE	100 mCi	ORAL	NDA	23 sections
HICON	HUMAN PRESCRIPTION DRUG LABEL	1	65174-880	SOLUTION	1000 mCi	ORAL	NDA	25 sections
HICON	HUMAN PRESCRIPTION DRUG LABEL	1	65174-880	SOLUTION	1 mCi	ORAL	NDA	25 sections