turoctocog alfa 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
blood factor VIII 5019 1192451-26-5

Description:

MoleculeDescription

Synonyms:

  • turoctocog alfa
  • turoctocog alfa (genetical recombination)
  • novoeight
  • coagulation factor VIII
a recombinant coagulation factor VIII for prevention and treatment of bleeding in haemophilia A
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Nov. 13, 2013 EMA Novo Nordisk A/S
Jan. 17, 2014 PMDA Novo Nordisk Pharma Ltd.

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Carotid artery dissection 32.60 24.47 3 3 164 34956761

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Carotid artery dissection 32.79 26.34 3 3 354 79744028

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B02BD02 BLOOD AND BLOOD FORMING ORGANS
ANTIHEMORRHAGICS
VITAMIN K AND OTHER HEMOSTATICS
Blood coagulation factors
ATC B02BD06 BLOOD AND BLOOD FORMING ORGANS
ANTIHEMORRHAGICS
VITAMIN K AND OTHER HEMOSTATICS
Blood coagulation factors

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hereditary factor VIII deficiency disease indication 28293008 DOID:12134




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D10227 KEGG_DRUG
4019616 VANDF
4029702 VANDF
CHEMBL2108286 ChEMBL_ID
C577506 MESH_SUPPLEMENTAL_RECORD_UI
DB09109 DRUGBANK_ID
1607560 RXNORM
239004 MMSL
d00525 MMSL
d05974 MMSL
002035 NDDF
003830 NDDF
015757 NDDF
278910002 SNOMEDCT_US
416523005 SNOMEDCT_US
735055007 SNOMEDCT_US
C3529563 UMLSCUI
C0015506 UMLSCUI
9412 INN_ID
969NZA3X9T UNII

Pharmaceutical products:

None