sonidegib 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
SMO receptor antagonists 5008 956697-53-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • sonidegib diphosphate
  • sonidegib
  • odomzo
  • LDE225
  • erismodegib
  • LDE-225
  • NPV-LDE-225
  • sonidegib phosphate
specific Smoothened/Smo antagonist
  • Molecular weight: 485.51
  • Formula: C26H26F3N3O3
  • CLOGP: 6.09
  • LIPINSKI: 1
  • HAC: 6
  • HDO: 1
  • TPSA: 63.69
  • ALOGS: -5.50
  • ROTB: 6
  • Status: ONP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

sonidegib