adalimumab 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
human origin 4904 331731-18-1

Description:

MoleculeDescription

Synonyms:

  • yuflym
  • ADALIMUMAB-ADBM
  • adalimumab-atto
  • amjevita
  • adalimumab
  • humira
  • adalimumab (genetical recombination)
  • LU200134
  • D2E7
A humanized monoclonal antibody that binds specifically to TNF-ALPHA and blocks its interaction with endogenous TNF RECEPTORS to modulate INFLAMMATION. It is used in the treatment of RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS; CROHN'S DISEASE and ULCERATIVE COLITIS.
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2.90 mg P

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
April 16, 2008 PMDA AbbVie GK
Sept. 8, 2003 EMA AbbVie Deutschland GmbH Co. KG
Dec. 31, 2002 FDA ABBVIE INC

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug ineffective 7966.20 10.97 30883 872241 1353415 88371908
Therapy interrupted 4973.68 10.97 4069 899055 46039 89679284
Drug intolerance 2786.19 10.97 10284 892840 437307 89288016
Therapeutic product effect decreased 2275.48 10.97 7000 896124 270571 89454752
Contraindicated product administered 2213.14 10.97 7617 895507 312522 89412801
Synovitis 2086.50 10.97 7621 895503 322131 89403192
Treatment failure 2050.64 10.97 7174 895950 296754 89428569
Joint swelling 2042.52 10.97 10160 892964 493140 89232183
Toxicity to various agents 1964.13 10.97 270 902854 287576 89437747
Drug interaction 1725.76 10.97 331 902793 276122 89449201
Hypotension 1689.13 10.97 568 902556 324829 89400494
Acute kidney injury 1639.24 10.97 573 902551 319814 89405509
Arthropathy 1593.42 10.97 7546 895578 358696 89366627
Systemic lupus erythematosus 1592.38 10.97 7481 895643 354415 89370908
Febrile neutropenia 1381.36 10.97 43 903081 158306 89567017
Completed suicide 1300.38 10.97 30 903094 145028 89580295
Pemphigus 1273.59 10.97 6528 896596 320336 89404987
Alopecia 1271.42 10.97 8863 894261 486208 89239115
Therapeutic product effect incomplete 1262.38 10.97 4526 898598 189370 89535953
Arthralgia 1201.43 10.97 12434 890690 766088 88959235
Neutropenia 1165.90 10.97 393 902731 224511 89500812
Glossodynia 1119.46 10.97 6230 896894 315549 89409774
Hand deformity 1112.06 10.97 5858 897266 290504 89434819
Swelling 969.93 10.97 7320 895804 411738 89313585
Somnolence 951.52 10.97 446 902678 208638 89516685
Psoriasis 940.10 10.97 3424 899700 144330 89580993
Abdominal discomfort 930.62 10.97 8017 895107 469311 89256012
Anaemia 889.69 10.97 1336 901788 351466 89373857
Intentional overdose 866.96 10.97 13 903111 93821 89631502
Musculoskeletal stiffness 843.90 10.97 5449 897675 291083 89434240
Death 841.11 10.97 2085 901039 454466 89270857
Dyspnoea 829.44 10.97 5264 897860 875691 88849632
Infection 825.64 10.97 6304 896820 355790 89369533
Malignant neoplasm progression 824.39 10.97 63 903061 106807 89618516
Hyponatraemia 805.51 10.97 173 902951 133365 89591958
Wound 790.17 10.97 5448 897676 297532 89427791
Drug abuse 758.26 10.97 12 903112 82335 89642988
Pain 752.28 10.97 14010 889114 982331 88742992
Hepatic enzyme increased 720.27 10.97 6093 897031 354643 89370680
Anti-cyclic citrullinated peptide antibody positive 712.31 10.97 4409 898715 232024 89493299
Platelet count decreased 701.52 10.97 244 902880 136725 89588598
Disease progression 685.28 10.97 352 902772 156263 89569060
Constipation 677.82 10.97 1092 902032 279303 89446020
Electrocardiogram QT prolonged 653.11 10.97 14 903110 72442 89652881
Rheumatoid factor positive 651.97 10.97 3406 899718 168244 89557079
Thrombocytopenia 649.81 10.97 672 902452 208053 89517270
C-reactive protein abnormal 635.97 10.97 2737 900387 124692 89600631
Oxygen saturation decreased 632.61 10.97 147 902977 107336 89617987
Product dose omission issue 622.18 10.97 1228 901896 290459 89434864
Bradycardia 607.45 10.97 64 903060 83783 89641540
White blood cell count decreased 604.04 10.97 468 902656 166641 89558682
Pericarditis 595.04 10.97 4667 898457 265484 89459839
Intestinal stenosis 570.93 10.97 374 902750 2900 89722423
Rheumatoid arthritis 570.64 10.97 5821 897303 356793 89368530
Pancytopenia 568.18 10.97 243 902881 120020 89605303
Cardiac arrest 567.29 10.97 170 902954 104765 89620558
Red blood cell sedimentation rate increased 550.56 10.97 1944 901180 80651 89644672
Tremor 544.73 10.97 436 902688 152737 89572586
Injection site pain 520.26 10.97 3235 899889 170464 89554859
Neutrophil count decreased 517.16 10.97 55 903069 71477 89653846
Fall 513.31 10.97 2764 900360 479046 89246277
Rash 511.75 10.97 10933 892191 785167 88940156
Inflammation 508.80 10.97 3284 899840 175308 89550015
Dehydration 501.76 10.97 724 902400 193723 89531600
Blood pressure increased 500.41 10.97 743 902381 196474 89528849
Depressed level of consciousness 498.96 10.97 67 903057 72717 89652606
Drug hypersensitivity 489.90 10.97 6898 896226 456711 89268612
Diarrhoea 484.26 10.97 6527 896597 932663 88792660
Discomfort 479.28 10.97 4502 898622 269833 89455490
Cough 477.85 10.97 1972 901152 366990 89358333
Multiple sclerosis relapse 475.84 10.97 9 903115 52296 89673027
Chest discomfort 472.09 10.97 410 902714 137955 89587368
Seizure 472.02 10.97 494 902630 152135 89573188
Mobility decreased 471.12 10.97 4180 898944 246554 89478769
Hypoxia 470.18 10.97 78 903046 72321 89653002
Agitation 464.19 10.97 60 903064 67038 89658285
Hypersensitivity 461.97 10.97 6719 896405 447958 89277365
Lactic acidosis 461.88 10.97 8 903116 50455 89674868
Red blood cell sedimentation rate abnormal 457.05 10.97 846 902278 23358 89701965
Suicide attempt 456.02 10.97 97 903027 75302 89650021
Helicobacter infection 442.85 10.97 3814 899310 223036 89502287
Hypokalaemia 439.51 10.97 395 902729 130721 89594602
Sedation 439.40 10.97 8 903116 48163 89677160
Ileal stenosis 439.27 10.97 286 902838 2192 89723131
Hyperkalaemia 433.16 10.97 65 903059 64899 89660424
Heart rate increased 430.24 10.97 299 902825 112603 89612720
Neuropathy peripheral 428.42 10.97 439 902685 136531 89588792
Tachycardia 417.76 10.97 576 902548 157097 89568226
Osteoarthritis 414.62 10.97 3352 899772 192378 89532945
Atrial fibrillation 412.52 10.97 433 902691 133178 89592145
Metabolic acidosis 412.42 10.97 39 903085 55637 89669686
Loss of personal independence in daily activities 406.29 10.97 2533 900591 133572 89591751
Coma 393.78 10.97 117 903007 72515 89652808
Hallucination 390.51 10.97 89 903035 65870 89659453
Myelosuppression 390.51 10.97 40 903084 53551 89671772
Duodenal ulcer perforation 388.60 10.97 3636 899488 217652 89507671
Nausea 388.46 10.97 8280 894844 1102036 88623287
Lupus-like syndrome 388.04 10.97 1220 901904 47626 89677697
Cognitive disorder 387.02 10.97 106 903018 69301 89656022
Cardio-respiratory arrest 386.44 10.97 79 903045 63061 89662262
Asthenia 382.61 10.97 3438 899686 530313 89195010
Overdose 374.49 10.97 621 902503 157088 89568235
Respiratory failure 374.37 10.97 376 902748 118042 89607281
Anal fistula 374.29 10.97 324 902800 3977 89721346
Hypoglycaemia 370.59 10.97 117 903007 69731 89655592
Arthritis 367.21 10.97 2889 900235 164426 89560897
Balance disorder 366.07 10.97 260 902864 96820 89628503
Neoplasm progression 364.56 10.97 19 903105 44467 89680856
Device expulsion 364.21 10.97 9 903115 40877 89684446
Injection site reaction 361.77 10.97 1845 901279 90235 89635088
Rhabdomyolysis 359.02 10.97 44 903080 51212 89674111
Drug reaction with eosinophilia and systemic symptoms 357.67 10.97 16 903108 42742 89682581
Serotonin syndrome 355.44 10.97 4 903120 37883 89687440
Flushing 355.24 10.97 221 902903 88270 89637053
Impaired healing 352.96 10.97 3728 899396 230471 89494852
International normalised ratio increased 348.21 10.97 34 903090 47282 89678041
C-reactive protein increased 347.79 10.97 3038 900086 178351 89546972
Therapy cessation 347.71 10.97 970 902154 35391 89689932
Large intestinal stenosis 347.12 10.97 248 902876 2249 89723074
Dizziness 339.21 10.97 3998 899126 585286 89140037
Product use issue 338.89 10.97 4886 898238 325033 89400290
Blood pressure decreased 329.49 10.97 167 902957 74728 89650595
Encephalopathy 327.44 10.97 39 903085 46405 89678918
Maternal exposure during pregnancy 322.31 10.97 5209 897915 354854 89370469
Hyperglycaemia 322.02 10.97 59 903065 50911 89674412
Bone erosion 317.08 10.97 1205 901919 51816 89673507
Haemoglobin decreased 315.63 10.97 717 902407 161239 89564084
Adverse drug reaction 315.23 10.97 2118 901006 114583 89610740
Vomiting 312.62 10.97 5754 897370 782539 88942784
Renal failure 310.88 10.97 516 902608 130491 89594832
Gastrointestinal haemorrhage 305.89 10.97 269 902855 89979 89635344
Syncope 303.37 10.97 535 902589 132128 89593195
Dysphagia 298.55 10.97 409 902715 111869 89613454
Renal impairment 296.77 10.97 368 902756 105053 89620270
Knee arthroplasty 293.42 10.97 1618 901506 81564 89643759
Folliculitis 293.03 10.97 3221 899903 201132 89524191
Orthostatic hypotension 292.72 10.97 36 903088 41791 89683532
Injection site papule 290.92 10.97 154 902970 758 89724565
Epistaxis 290.61 10.97 252 902872 84873 89640450
Infusion related reaction 279.78 10.97 5764 897360 411016 89314307
Agranulocytosis 277.51 10.97 18 903106 34984 89690339
Blood iron abnormal 275.77 10.97 265 902859 3755 89721568
Psoriatic arthropathy 274.36 10.97 3479 899645 224856 89500467
Joint stiffness 271.25 10.97 1512 901612 76530 89648793
Drug specific antibody present 269.31 10.97 303 902821 5211 89720112
Heart rate decreased 269.29 10.97 98 903026 53407 89671916
Condition aggravated 268.17 10.97 7799 895325 587746 89137577
Blood pressure systolic increased 267.48 10.97 123 903001 58222 89667101
Multiple organ dysfunction syndrome 264.29 10.97 178 902946 68158 89657165
Mucosal inflammation 263.37 10.97 122 903002 57503 89667820
Dyspnoea exertional 262.94 10.97 201 902923 72087 89653236
Pyoderma gangrenosum 259.60 10.97 269 902855 4195 89721128
Cardiac failure congestive 257.91 10.97 364 902760 98330 89626993
Blood glucose increased 257.23 10.97 343 902781 94903 89630420
Palmar-plantar erythrodysaesthesia syndrome 254.18 10.97 5 903119 28018 89697305
Blood creatinine increased 252.17 10.97 387 902737 100999 89624324
Gastrointestinal inflammation 251.57 10.97 322 902802 6374 89718949
Toxic epidermal necrolysis 251.30 10.97 19 903105 32509 89692814
Irritable bowel syndrome 251.00 10.97 3165 899959 204283 89521040
Blood bilirubin increased 246.87 10.97 64 903060 43406 89681917
Mental status changes 245.80 10.97 70 903054 44609 89680714
Intestinal obstruction 245.67 10.97 872 902252 36259 89689064
Palpitations 245.31 10.97 632 902492 136096 89589227
Cardiac failure 241.02 10.97 452 902672 109044 89616279
Tuberculin test positive 239.52 10.97 237 902887 3488 89721835
Hepatic function abnormal 239.44 10.97 81 903043 46207 89679116
Pneumonia aspiration 238.86 10.97 57 903067 40883 89684440
Plasma cell myeloma 237.90 10.97 57 903067 40771 89684552
Pustular psoriasis 237.79 10.97 553 902571 18003 89707320
Rheumatic fever 236.48 10.97 2450 900674 150671 89574652
Hip arthroplasty 234.68 10.97 1430 901694 74778 89650545
Fibromyalgia 234.40 10.97 3111 900013 203158 89522165
Lethargy 231.65 10.97 174 902950 62965 89662358
Deep vein thrombosis 230.49 10.97 347 902777 91273 89634050
Blood cholesterol increased 229.25 10.97 3120 900004 204892 89520431
Blood pressure fluctuation 228.86 10.97 118 903006 52295 89673028
Uveitis 228.46 10.97 496 902628 15407 89709916
Intentional dose omission 227.92 10.97 530 902594 17253 89708070
Hypervolaemia 227.27 10.97 29 903095 32728 89692595
Joint range of motion decreased 227.13 10.97 2207 900917 133436 89591887
Unresponsive to stimuli 226.53 10.97 51 903073 38070 89687253
Dysarthria 225.76 10.97 131 902993 54351 89670972
Hypomagnesaemia 225.24 10.97 41 903083 35547 89689776
Drug withdrawal syndrome 224.12 10.97 16 903108 28707 89696616
Injection site erythema 223.29 10.97 1714 901410 96788 89628535
Peripheral swelling 222.31 10.97 5538 897586 407568 89317755
Muscle injury 221.33 10.97 2713 900411 173941 89551382
Hidradenitis 219.39 10.97 243 902881 4104 89721219
Abdominal adhesions 219.03 10.97 221 902903 3334 89721989
Intentional self-injury 218.72 10.97 20 903104 29314 89696009
Pulmonary arterial hypertension 218.37 10.97 10 903114 26177 89699146
Respiratory arrest 218.26 10.97 35 903089 33276 89692047
Rheumatoid nodule 218.03 10.97 563 902561 19603 89705720
Myalgia 217.16 10.97 951 902173 174174 89551149
Pulmonary embolism 215.76 10.97 630 902494 130190 89595133
Fistula 215.13 10.97 412 902712 11677 89713646
Acute respiratory failure 213.64 10.97 80 903044 42838 89682485
Disturbance in attention 213.34 10.97 101 903023 47008 89678315
Pulmonary oedema 211.63 10.97 184 902940 61896 89663427
Suicidal ideation 209.76 10.97 256 902868 73599 89651724
Disorientation 208.52 10.97 89 903035 44025 89681298
Sepsis 207.79 10.97 1002 902122 178812 89546511
Full blood count abnormal 207.60 10.97 54 903070 36543 89688780
Nasal congestion 204.96 10.97 321 902803 83093 89642230
Dyskinesia 201.42 10.97 57 903067 36477 89688846
Ankylosing spondylitis 200.65 10.97 420 902704 12713 89712610
Angioedema 199.34 10.97 211 902913 64665 89660658
Injection site haemorrhage 198.59 10.97 678 902446 27640 89697683
Swollen joint count increased 198.40 10.97 1834 901290 109372 89615951
Gastrointestinal disorder 198.15 10.97 3627 899497 253060 89472263
Dysgeusia 197.82 10.97 141 902983 52419 89672904
Full blood count decreased 197.23 10.97 30 903094 29659 89695664
Paradoxical psoriasis 196.25 10.97 88 903036 276 89725047
Grip strength decreased 196.15 10.97 1586 901538 90990 89634333
Osteonecrosis of jaw 194.46 10.97 73 903051 39030 89686293
Drug specific antibody 192.30 10.97 176 902948 2336 89722987
Anxiety 191.88 10.97 2066 901058 307706 89417617
Altered state of consciousness 189.76 10.97 41 903083 31491 89693832
Pleural effusion 189.31 10.97 533 902591 111458 89613865
Musculoskeletal pain 189.21 10.97 2570 900554 168681 89556642
Surgery 186.56 10.97 914 902210 43973 89681350
Restlessness 185.65 10.97 62 903062 35658 89689665
Melaena 185.09 10.97 58 903066 34739 89690584
Off label use 184.33 10.97 9045 894079 1093207 88632116
Pulmonary fibrosis 182.83 10.97 1755 901369 105748 89619575
Lymphocyte count decreased 181.88 10.97 61 903063 34989 89690334
Dry skin 179.70 10.97 380 902744 87693 89637630
Cholestasis 178.45 10.97 69 903055 36230 89689093
Foot deformity 178.41 10.97 1111 902013 58540 89666783
Ill-defined disorder 176.21 10.97 2704 900420 182187 89543136
Psychotic disorder 175.40 10.97 47 903077 31183 89694140
Obstructive airways disorder 174.49 10.97 25 903099 25844 89699479
Hallucination, visual 174.18 10.97 15 903109 23077 89702246
Sleep disorder due to general medical condition, insomnia type 173.72 10.97 2005 901119 126689 89598634
Dysphonia 173.58 10.97 224 902900 62860 89662463
Creatinine renal clearance decreased 172.93 10.97 3 903121 18896 89706427
Demyelination 172.21 10.97 299 902825 7841 89717482
Tuberculosis 171.90 10.97 384 902740 12165 89713158
Bone pain 171.68 10.97 219 902905 61764 89663559
Inappropriate schedule of product administration 171.18 10.97 839 902285 149094 89576229
Abscess 170.89 10.97 494 902630 18397 89706926
Aggression 170.34 10.97 30 903094 26638 89698685
Respiratory distress 169.57 10.97 88 903036 38858 89686465
Pulmonary hypertension 169.54 10.97 107 903017 42416 89682907
Acute hepatic failure 169.24 10.97 15 903109 22546 89702777
Intestinal fistula 169.03 10.97 114 903010 933 89724390
Status epilepticus 168.70 10.97 4 903120 18870 89706453
Neurotoxicity 167.38 10.97 12 903112 21455 89703868
Feeling abnormal 166.99 10.97 979 902145 166256 89559067
Deformity 166.26 10.97 372 902752 11798 89713525
Musculoskeletal disorder 165.83 10.97 536 902588 21233 89704090
Hepatic cytolysis 165.39 10.97 51 903073 30865 89694458
Type 2 diabetes mellitus 165.34 10.97 2896 900228 200348 89524975
Blood pressure diastolic decreased 165.32 10.97 33 903091 26793 89698530
No adverse event 164.75 10.97 264 902860 67718 89657605
Drug level increased 163.25 10.97 38 903086 27724 89697599
Blister 162.20 10.97 3500 899624 251498 89473825
Haematoma 161.63 10.97 94 903030 38954 89686369
Rhinorrhoea 160.10 10.97 406 902718 87910 89637413
Hepatic failure 159.73 10.97 99 903025 39629 89685694
Inappropriate antidiuretic hormone secretion 157.74 10.97 9 903115 19496 89705827
Productive cough 157.64 10.97 332 902792 76731 89648592
Ventricular tachycardia 157.37 10.97 28 903096 24680 89700643
Blood alkaline phosphatase increased 157.32 10.97 148 902976 47931 89677392
Tenosynovitis 156.77 10.97 406 902718 14161 89711162
Premature delivery 156.67 10.97 96 903028 38666 89686657
Faecal calprotectin increased 156.56 10.97 196 902928 3791 89721532
Bone marrow failure 155.52 10.97 63 903061 32158 89693165
Intestinal resection 155.33 10.97 168 902956 2759 89722564
Liver function test increased 155.18 10.97 1407 901717 83448 89641875
Nasopharyngitis 154.79 10.97 5225 897899 401879 89323444
Generalised tonic-clonic seizure 154.75 10.97 77 903047 34826 89690497
Colectomy 154.26 10.97 179 902945 3188 89722135
Infusion site pain 153.99 10.97 11 903113 19727 89705596
Vision blurred 153.67 10.97 572 902552 109721 89615602
Panniculitis 153.59 10.97 401 902723 14057 89711266
Small intestinal obstruction 152.95 10.97 513 902611 20721 89704602
Injection site pruritus 152.55 10.97 989 902135 52845 89672478
Dermatitis psoriasiform 151.77 10.97 159 902965 2513 89722810
Ileostomy 151.72 10.97 138 902986 1816 89723507
Finger deformity 149.92 10.97 688 902436 32209 89693114
Joint effusion 149.87 10.97 485 902639 19225 89706098
Injection site urticaria 149.64 10.97 457 902667 17554 89707769
Adverse reaction 149.48 10.97 640 902484 29072 89696251
Shock 149.47 10.97 50 903074 28728 89696595
Abscess intestinal 149.38 10.97 136 902988 1792 89723531
Gait inability 148.91 10.97 2166 900958 144290 89581033
Throat irritation 148.90 10.97 159 902965 48536 89676787
Diabetic ketoacidosis 148.39 10.97 31 903093 24376 89700947
Blood creatine phosphokinase increased 146.47 10.97 78 903046 33945 89691378
Tachypnoea 145.12 10.97 20 903104 21289 89704034
Blood pressure diastolic abnormal 144.42 10.97 15 903109 19866 89705457
Therapy non-responder 143.85 10.97 2034 901090 134670 89590653
Withdrawal syndrome 142.43 10.97 26 903098 22498 89702825
Stevens-Johnson syndrome 140.87 10.97 58 903066 29318 89696005
Drug delivery system malfunction 140.80 10.97 114 903010 1267 89724056
Thrombotic microangiopathy 138.22 10.97 4 903120 15739 89709584
Blood pressure systolic abnormal 138.19 10.97 16 903108 19462 89705861
Ejection fraction decreased 137.43 10.97 45 903079 26208 89699115
Sinus tachycardia 137.22 10.97 56 903068 28457 89696866
Sinus bradycardia 136.54 10.97 8 903116 16944 89708379
Blood calcium decreased 136.22 10.97 65 903059 30117 89695206
Neutropenic sepsis 136.14 10.97 12 903112 18118 89707205
Intestinal anastomosis 136.11 10.97 95 903029 827 89724496
Deafness transitory 135.11 10.97 132 902992 1911 89723412
Haematemesis 134.27 10.97 85 903039 33641 89691682
Arrhythmia 134.22 10.97 134 902990 42198 89683125
Upper gastrointestinal haemorrhage 134.01 10.97 32 903092 22944 89702379
Illness 132.92 10.97 1325 901799 80644 89644679
Bursitis 132.62 10.97 1944 901180 129710 89595613
Chills 132.61 10.97 771 902353 131210 89594113
Anal stenosis 132.22 10.97 77 903047 471 89724852
Accidental overdose 132.10 10.97 58 903066 28215 89697108
Enthesopathy 131.33 10.97 290 902834 9114 89716209
Arthrodesis 131.14 10.97 156 902968 2856 89722467
Extrapyramidal disorder 130.39 10.97 8 903116 16295 89709028
Coordination abnormal 130.09 10.97 27 903097 21329 89703994
Respiratory depression 129.70 10.97 6 903118 15569 89709754
Disseminated tuberculosis 129.26 10.97 162 902962 3137 89722186
Torsade de pointes 129.25 10.97 5 903119 15177 89710146
Right ventricular failure 128.51 10.97 19 903105 19186 89706137
Basal cell carcinoma 127.59 10.97 664 902460 32725 89692598
Urinary incontinence 127.24 10.97 112 903012 37454 89687869
Cerebrovascular accident 126.61 10.97 717 902407 122816 89602507
Gamma-glutamyltransferase increased 126.33 10.97 115 903009 37837 89687486
Joint destruction 124.60 10.97 352 902772 12935 89712388
Respiratory rate increased 124.59 10.97 9 903115 15992 89709331
Hepatocellular injury 123.76 10.97 67 903057 28891 89696432
Pancreatitis acute 123.70 10.97 84 903040 32031 89693292
Myoclonus 123.66 10.97 21 903103 19147 89706176
Speech disorder 123.22 10.97 164 902960 45421 89679902
Granuloma skin 122.57 10.97 305 902819 10375 89714948
Liver injury 122.19 10.97 2383 900741 168184 89557139
Injection site irritation 122.14 10.97 217 902907 5798 89719525
Oedema peripheral 121.99 10.97 1821 901303 256094 89469229
Blood parathyroid hormone decreased 121.85 10.97 331 902793 11885 89713438
Ascites 121.82 10.97 179 902945 47561 89677762
Infusion site erythema 121.79 10.97 3 903121 13667 89711656
Cerebral haemorrhage 121.74 10.97 99 903025 34423 89690900
Aphasia 120.93 10.97 149 902975 42663 89682660
Body temperature increased 120.71 10.97 161 902963 44549 89680774
Urinary retention 120.22 10.97 119 903005 37625 89687698
Labelled drug-drug interaction medication error 120.20 10.97 6 903118 14576 89710747
Circulatory collapse 119.70 10.97 49 903075 24855 89700468
Small intestinal stenosis 119.69 10.97 80 903044 644 89724679
Product use in unapproved indication 119.18 10.97 2499 900625 333737 89391586
Back pain 119.08 10.97 2335 900789 314840 89410483
Irritability 118.78 10.97 108 903016 35554 89689769
Anal abscess 118.58 10.97 208 902916 5500 89719823
Adverse event 118.34 10.97 1734 901390 115684 89609639
Shoulder arthroplasty 118.30 10.97 175 902949 3991 89721332
Abnormal behaviour 118.08 10.97 39 903085 22589 89702734
Joint injury 117.59 10.97 639 902485 32025 89693298
Jaundice 117.50 10.97 91 903033 32426 89692897
Subdural haematoma 117.27 10.97 14 903110 16631 89708692
Hyperhidrosis 117.18 10.97 835 902289 135470 89589853
Hyperlipidaemia 116.97 10.97 41 903083 22875 89702448
Blood urea increased 116.54 10.97 80 903044 30333 89694990
Metastases to bone 116.54 10.97 54 903070 25451 89699872
Cardiogenic shock 116.22 10.97 49 903075 24419 89700904
Parkinsonism 115.26 10.97 6 903118 14059 89711264
Hyperbilirubinaemia 114.03 10.97 6 903118 13930 89711393
Acute myocardial infarction 113.45 10.97 108 903016 34782 89690541
Frequent bowel movements 112.34 10.97 960 902164 55975 89669348
Posterior reversible encephalopathy syndrome 112.26 10.97 41 903083 22298 89703025
Pruritus allergic 111.99 10.97 111 903013 1637 89723686
Fear of injection 111.56 10.97 256 902868 8259 89717064
Surgical failure 110.94 10.97 86 903038 893 89724430
Electrolyte imbalance 110.48 10.97 49 903075 23696 89701627
Product administration error 110.23 10.97 63 903061 26360 89698963
Malignant melanoma 110.05 10.97 325 902799 12251 89713072
Coagulopathy 110.04 10.97 47 903077 23242 89702081
Nodule 109.90 10.97 542 902582 26144 89699179
Personality disorder 109.85 10.97 3 903121 12441 89712882
Inflammatory bowel disease 109.47 10.97 190 902934 4981 89720342
Furuncle 107.67 10.97 235 902889 7326 89717997
Alanine aminotransferase increased 107.62 10.97 713 902411 117625 89607698
Metastases to central nervous system 107.22 10.97 22 903102 17520 89707803
Joint dislocation 106.77 10.97 786 902338 43796 89681527
Dermatitis allergic 106.23 10.97 397 902727 16930 89708393
Haemorrhage intracranial 106.21 10.97 13 903111 15149 89710174
Weight decreased 105.39 10.97 2930 900194 376980 89348343
Gastrointestinal wall thickening 105.34 10.97 118 903006 2019 89723304
Palmoplantar pustulosis 104.29 10.97 69 903055 545 89724778
Pericardial effusion 104.24 10.97 128 902996 36705 89688618
Intentional product misuse 103.64 10.97 499 902625 89105 89636218
Polyarthritis 103.13 10.97 409 902715 17941 89707382
Muscle spasticity 102.89 10.97 120 903004 35202 89690121
Hypothermia 102.86 10.97 16 903108 15559 89709764
Injury 102.79 10.97 2635 900489 194714 89530609
Blood potassium increased 102.73 10.97 39 903085 20710 89704613
Angina pectoris 102.71 10.97 144 902980 39016 89686307
Intestinal fibrosis 102.55 10.97 49 903075 185 89725138
Chest pain 102.32 10.97 2414 900710 317231 89408092
Poisoning 101.95 10.97 15 903109 15202 89710121
Mania 101.72 10.97 11 903113 14113 89711210
Acute respiratory distress syndrome 101.48 10.97 82 903042 28604 89696719
Disseminated intravascular coagulation 100.92 10.97 44 903080 21494 89703829
Rhinitis allergic 100.65 10.97 22 903102 16763 89708560
Decreased appetite 100.64 10.97 2919 900205 373621 89351702
Cytopenia 100.41 10.97 25 903099 17424 89707899
Chronic obstructive pulmonary disease 100.17 10.97 387 902737 73442 89651881
Emotional distress 100.01 10.97 131 902993 36531 89688792
Disability 99.67 10.97 722 902402 40023 89685300
Pallor 99.59 10.97 116 903008 34049 89691274
Pneumonitis 99.25 10.97 180 902944 43990 89681333
Lymphopenia 99.17 10.97 52 903072 22829 89702494
Live birth 99.03 10.97 1215 901909 77892 89647431
Dystonia 98.94 10.97 23 903101 16796 89708527
Injection site rash 98.86 10.97 490 902634 23683 89701640
Blood sodium decreased 98.86 10.97 78 903046 27535 89697788
Hypophosphataemia 98.69 10.97 15 903109 14839 89710484
Blood lactate dehydrogenase increased 98.32 10.97 69 903055 25863 89699460
Presyncope 98.20 10.97 103 903021 31702 89693621
Hallucination, auditory 97.72 10.97 20 903104 15955 89709368
Sinusitis 96.72 10.97 4262 898862 338826 89386497
Chronic kidney disease 96.27 10.97 224 902900 49967 89675356
Device dislocation 96.03 10.97 103 903021 31379 89693944
Mydriasis 95.64 10.97 17 903107 14995 89710328
Intestinal anastomosis complication 95.27 10.97 53 903071 293 89725030
Tardive dyskinesia 95.15 10.97 3 903121 10927 89714396
Herpes zoster 95.09 10.97 1397 901727 93247 89632076
Sacroiliitis 94.56 10.97 159 902965 4060 89721263
Rectal stenosis 94.37 10.97 48 903076 214 89725109
General physical health deterioration 94.14 10.97 4384 898740 350731 89374592
Musculoskeletal deformity 93.90 10.97 105 903019 1793 89723530
Paternal drugs affecting foetus 93.56 10.97 31 903093 26 89725297
Infusion site swelling 92.99 10.97 6 903118 11714 89713609
Schizophrenia 92.63 10.97 18 903106 14896 89710427
Tooth disorder 92.31 10.97 104 903020 30986 89694337
Immunodeficiency 92.26 10.97 742 902382 42492 89682831
Ileal ulcer 92.15 10.97 80 903044 986 89724337
Eosinophilia 91.98 10.97 89 903035 28444 89696879
Gastrointestinal stenosis 91.96 10.97 49 903075 245 89725078
Synovial cyst 91.91 10.97 292 902832 11460 89713863
Depressed mood 91.69 10.97 230 902894 49992 89675331
Coeliac disease 91.09 10.97 758 902366 43852 89681471
Urinary tract infection 90.79 10.97 2334 900790 303298 89422025
Antinuclear antibody positive 90.78 10.97 249 902875 8992 89716331
Blood glucose decreased 90.62 10.97 61 903063 23368 89701955
Anhedonia 90.26 10.97 6 903118 11425 89713898
Pneumonia 90.06 10.97 5322 897802 632737 89092586
Leukopenia 89.97 10.97 610 902514 100100 89625223
Hot flush 89.90 10.97 298 902826 59190 89666133
Body temperature decreased 89.47 10.97 64 903060 23752 89701571
Bacteraemia 89.05 10.97 56 903068 22244 89703079
Eye pruritus 88.50 10.97 95 903029 28932 89696391
Muscle twitching 88.38 10.97 67 903057 24135 89701188
Impaired work ability 87.92 10.97 404 902720 18922 89706401
Mycobacterium tuberculosis complex test positive 87.90 10.97 119 903005 2493 89722830
Akathisia 87.69 10.97 6 903118 11153 89714170
Facet joint syndrome 87.64 10.97 1423 901701 96966 89628357
Shock haemorrhagic 87.01 10.97 10 903114 12235 89713088
Product administration interrupted 86.80 10.97 11 903113 12481 89712842
Inflammatory marker increased 86.31 10.97 244 902880 8970 89716353
Sciatica 86.14 10.97 1455 901669 99927 89625396
Hypothyroidism 86.00 10.97 258 902866 52869 89672454
Nervousness 85.62 10.97 129 902995 33927 89691396
Anastomotic stenosis 85.51 10.97 53 903071 369 89724954
Sneezing 85.37 10.97 103 903021 29766 89695557
Skin ulcer 85.36 10.97 818 902306 49257 89676066
Delusion 85.34 10.97 17 903107 13823 89711500
Intestinal mucosal hypertrophy 85.09 10.97 46 903078 238 89725085
Sleep apnoea syndrome 85.01 10.97 115 903009 31632 89693691
Aspartate aminotransferase increased 84.90 10.97 638 902486 102299 89623024
Lip dry 84.73 10.97 1446 901678 99509 89625814
Hypocalcaemia 84.59 10.97 185 902939 42183 89683140
Blood potassium decreased 84.50 10.97 222 902902 47505 89677818
Gastrointestinal fistula 84.41 10.97 58 903066 491 89724832
Drug tolerance decreased 83.64 10.97 578 902546 31552 89693771
Cytomegalovirus infection 83.43 10.97 85 903039 26517 89698806
Muscle rigidity 83.31 10.97 20 903104 14289 89711034
Transfusion 83.10 10.97 35 903089 17453 89707870
Affect lability 82.91 10.97 38 903086 18025 89707298
Antinuclear antibody increased 82.27 10.97 82 903042 1218 89724105
Accidental exposure to product 82.12 10.97 188 902936 42178 89683145
Nightmare 82.11 10.97 58 903066 21667 89703656
Acute generalised exanthematous pustulosis 82.09 10.97 18 903106 13685 89711638
Allergic oedema 81.53 10.97 71 903053 879 89724444
Miosis 81.16 10.97 3 903121 9481 89715842
Body height below normal 81.04 10.97 104 903020 2064 89723259
Limb deformity 80.74 10.97 147 902977 4005 89721318
Hepatic encephalopathy 80.68 10.97 19 903105 13753 89711570
Metastases to liver 80.58 10.97 101 903023 28706 89696617
Guttate psoriasis 80.55 10.97 58 903066 533 89724790
Eye irritation 80.41 10.97 134 902990 33844 89691479
Dysuria 80.36 10.97 170 902954 39231 89686092
Dactylitis 80.29 10.97 141 902983 3732 89721591
Gastrointestinal scarring 80.03 10.97 52 903072 397 89724926
Bronchospasm 79.98 10.97 54 903070 20655 89704668
Acidosis 79.89 10.97 15 903109 12721 89712602
Contrast media allergy 79.80 10.97 124 903000 2957 89722366
Dementia 79.78 10.97 72 903052 23789 89701534
Fistula discharge 79.73 10.97 74 903050 1001 89724322
Renal tubular necrosis 79.70 10.97 23 903101 14532 89710791
Renal disorder 79.20 10.97 161 902963 37698 89687625
Pollakiuria 79.19 10.97 129 902995 32876 89692447
Rash maculo-papular 79.05 10.97 182 902942 40751 89684572
Gangrene 79.01 10.97 16 903108 12860 89712463
Ear infection 79 10.97 1052 902072 68723 89656600
Injection site swelling 78.80 10.97 928 902196 58911 89666412
Skin exfoliation 78.65 10.97 378 902746 67535 89657788
Ulcer 78.33 10.97 579 902545 32303 89693020
Lower respiratory tract infection 77.18 10.97 3143 899981 247516 89477807
Foetal death 77.03 10.97 409 902715 20314 89705009
Wound infection 76.99 10.97 1489 901635 104913 89620410
Rheumatoid lung 76.93 10.97 143 902981 3960 89721363
Hospice care 76.90 10.97 5 903119 9699 89715624
Ataxia 76.73 10.97 42 903082 18000 89707323
Investigation abnormal 76.67 10.97 104 903020 2183 89723140
Progressive multifocal leukoencephalopathy 76.55 10.97 30 903094 15625 89709698
Pulseless electrical activity 75.84 10.97 3 903121 8929 89716394
Blood pressure systolic decreased 75.82 10.97 4 903120 9266 89716057
Skin necrosis 75.49 10.97 352 902772 16589 89708734
Hypovolaemia 75.14 10.97 16 903108 12415 89712908
Vascular device infection 75.14 10.97 14 903110 11938 89713385
Fracture 74.54 10.97 66 903058 22010 89703313
Intestinal dilatation 74.36 10.97 103 903021 2207 89723116
Chromaturia 74.15 10.97 50 903074 19137 89706186
Prescribed overdose 74.01 10.97 1376 901748 96249 89629074
Cerebral infarction 73.61 10.97 94 903030 26502 89698821
Foot operation 73.48 10.97 227 902897 8774 89716549
Haemodynamic instability 73.27 10.97 14 903110 11725 89713598
Haemoptysis 72.90 10.97 138 902986 33182 89692141
Asthma 72.50 10.97 1847 901277 240313 89485010
Oral mucosal exfoliation 72.29 10.97 89 903035 1691 89723632
Osteoporosis 72.29 10.97 1358 901766 95173 89630150
Muscle spasms 72.28 10.97 1933 901191 249950 89475373
Feeling cold 72.02 10.97 101 903023 27364 89697959
Infusion site extravasation 71.99 10.97 9 903115 10319 89715004
Seasonal allergy 71.44 10.97 74 903050 22909 89702414
Nail disorder 71.26 10.97 901 902223 58166 89667157
Endometriosis 71.25 10.97 178 902946 6070 89719253
Carotid artery thrombosis 71.12 10.97 5 903119 9087 89716236
Cyanosis 70.86 10.97 54 903070 19401 89705922
Product dose omission in error 70.81 10.97 60 903064 20443 89704880
Adjustment disorder 70.75 10.97 7 903117 9635 89715688
Hypercholesterolaemia 70.67 10.97 1405 901719 99487 89625836
Diabetes mellitus inadequate control 70.46 10.97 50 903074 18634 89706689
Human antichimeric antibody positive 70.45 10.97 88 903036 1698 89723625
Hemiparesis 70.30 10.97 131 902993 31688 89693635
Stress cardiomyopathy 69.72 10.97 23 903101 13332 89711991
Mental impairment 69.55 10.97 40 903084 16680 89708643
Tinnitus 69.28 10.97 210 902914 42892 89682431
Pouchitis 69.26 10.97 56 903068 621 89724702
Drug ineffective for unapproved indication 69.25 10.97 385 902739 66259 89659064
Dermatitis atopic 69.16 10.97 79 903045 23393 89701930
Gastrointestinal obstruction 68.96 10.97 76 903048 1276 89724047
Septic shock 68.74 10.97 523 902601 83637 89641686
Haemorrhage 68.72 10.97 407 902717 68962 89656361
Rales 68.54 10.97 36 903088 15791 89709532
Neck pain 68.49 10.97 1552 901572 112411 89612912
Graft versus host disease 68.27 10.97 3 903121 8141 89717182
Restless legs syndrome 68.00 10.97 74 903050 22396 89702927
Pain in extremity 67.97 10.97 5291 897833 445238 89280085
Product label confusion 67.94 10.97 425 902699 22425 89702898
Oliguria 67.75 10.97 12 903112 10612 89714711
Nephropathy toxic 67.74 10.97 21 903103 12667 89712656
Head injury 67.50 10.97 130 902994 31058 89694265
Toxic encephalopathy 67.43 10.97 5 903119 8694 89716629
Cardiac disorder 67.36 10.97 314 902810 56558 89668765
Gastrointestinal pain 67.24 10.97 255 902869 10951 89714372
Glomerular filtration rate decreased 66.95 10.97 43 903081 16889 89708434
Product preparation error 66.73 10.97 11 903113 10250 89715073
Anaphylactic shock 66.52 10.97 134 902990 31483 89693840
Brain oedema 66.25 10.97 46 903078 17339 89707984
Salivary hypersecretion 65.68 10.97 7 903117 9085 89716238
COVID-19 pneumonia 65.51 10.97 51 903073 18126 89707197
X-ray abnormal 65.47 10.97 717 902407 44707 89680616
Transient ischaemic attack 65.44 10.97 216 902908 42960 89682363
Obesity 65.35 10.97 1443 901681 104064 89621259
Cholecystitis chronic 65.11 10.97 10 903114 9816 89715507
Abnormal dreams 65.02 10.97 16 903108 11241 89714082
Premature baby 64.98 10.97 93 903031 24984 89700339
Atrioventricular block complete 64.97 10.97 10 903114 9801 89715522
Cytomegalovirus infection reactivation 64.97 10.97 3 903121 7797 89717526
Adjustment disorder with depressed mood 64.80 10.97 857 902267 55896 89669427
Arthritis enteropathic 64.56 10.97 44 903080 367 89724956
Joint laxity 64.24 10.97 103 903021 2525 89722798
Complication of device insertion 63.97 10.97 13 903111 10423 89714900
Cervical dysplasia 63.96 10.97 131 902993 3903 89721420
Heart rate irregular 63.88 10.97 89 903035 24179 89701144
Red blood cell sedimentation rate 63.20 10.97 142 902982 4516 89720807
Stomatitis 62.94 10.97 3344 899780 271354 89453969
Small intestinal resection 62.93 10.97 53 903071 625 89724698
Haemolysis 62.92 10.97 6 903118 8504 89716819
Haemodialysis 62.52 10.97 7 903117 8740 89716583
Eosinophil count increased 62.44 10.97 26 903098 13055 89712268
Pulmonary toxicity 62.39 10.97 254 902870 11277 89714046
Complication associated with device 62.31 10.97 61 903063 19388 89705935
Pain in jaw 62.25 10.97 256 902868 47729 89677594
Parapsoriasis 62.23 10.97 29 903095 102 89725221
Urine output decreased 61.88 10.97 24 903100 12579 89712744
Dialysis 61.85 10.97 18 903106 11311 89714012
Clostridium difficile colitis 61.65 10.97 107 903017 26599 89698724
Ileocaecal resection 61.49 10.97 48 903076 504 89724819
Joint arthroplasty 61.25 10.97 118 903006 3359 89721964
Paranoia 61.07 10.97 26 903098 12882 89712441
Oropharyngeal pain 60.91 10.97 795 902329 114392 89610931
Coronary artery disease 60.59 10.97 155 902969 33468 89691855
Bronchitis chronic 60.38 10.97 141 902983 4602 89720721
Fine motor skill dysfunction 60.35 10.97 153 902971 5266 89720057
Blood lactic acid increased 60.34 10.97 8 903116 8770 89716553
Lip swelling 60.01 10.97 191 902933 38419 89686904
Subarachnoid haemorrhage 59.89 10.97 54 903070 17850 89707473
Cytomegalovirus viraemia 59.84 10.97 4 903120 7582 89717741
Sinus congestion 59.63 10.97 114 903010 27310 89698013
Diarrhoea haemorrhagic 59.39 10.97 237 902887 10426 89714897
Lung disorder 59.20 10.97 1933 901191 147950 89577373
Fluid retention 59.19 10.97 576 902548 87515 89637808
Erythema nodosum 59.01 10.97 157 902967 5567 89719756
Device related infection 58.90 10.97 104 903020 25682 89699641
Pyrexia 58.63 10.97 5726 897398 654759 89070564
Liver disorder 58.44 10.97 1603 901521 119666 89605657
Renal injury 58.31 10.97 15 903109 10228 89715095
Transplant rejection 58.31 10.97 27 903097 12731 89712592
Prothrombin time prolonged 58.21 10.97 13 903111 9759 89715564
Leukocytosis 58.08 10.97 140 902984 30850 89694473
Exostosis 58.05 10.97 796 902328 52338 89672985
Sleep disorder 57.96 10.97 2470 900654 195560 89529763
Haemolytic anaemia 57.89 10.97 22 903102 11675 89713648
Fistula of small intestine 57.85 10.97 43 903081 417 89724906
Upper-airway cough syndrome 57.74 10.97 40 903084 15095 89710228
Neuralgia 57.70 10.97 144 902980 31356 89693967
Hip fracture 57.69 10.97 155 902969 32922 89692401
Back injury 57.45 10.97 714 902410 45908 89679415
Bradyphrenia 57.26 10.97 5 903119 7607 89717716
Double stranded DNA antibody positive 57.12 10.97 42 903082 400 89724923
Haematuria 57.03 10.97 169 902955 34768 89690555
Hypoaesthesia 56.98 10.97 3746 899378 310464 89414859
Blood thyroid stimulating hormone increased 56.96 10.97 11 903113 9144 89716179
Vertigo 56.94 10.97 434 902690 69377 89655946
Musculoskeletal chest pain 56.81 10.97 93 903031 23657 89701666
Increased appetite 56.78 10.97 23 903101 11742 89713581
Respiratory acidosis 56.78 10.97 7 903117 8112 89717211
Confusional state 56.77 10.97 3208 899916 382997 89342326
Skin plaque 56.59 10.97 223 902901 9752 89715571
Enterocutaneous fistula 56.49 10.97 74 903050 1500 89723823
Troponin increased 56.36 10.97 31 903093 13250 89712073
Abdominal abscess 55.78 10.97 148 902976 5239 89720084
Psychomotor hyperactivity 55.70 10.97 29 903095 12784 89712539
Hypotonia 55.70 10.97 22 903102 11404 89713919
Eating disorder 55.69 10.97 123 903001 27950 89697373
Ileectomy 55.60 10.97 36 903088 273 89725050
Atrial flutter 55.33 10.97 19 903105 10739 89714584
Onychomycosis 55.27 10.97 593 902531 36783 89688540
Product complaint 55.16 10.97 33 903091 13467 89711856
Body height decreased 55.06 10.97 25 903099 11924 89713399
Acute myeloid leukaemia 55.03 10.97 75 903049 20565 89704758
Hemiplegia 54.94 10.97 48 903076 16112 89709211
Swollen tongue 54.85 10.97 253 902871 45703 89679620
Jaundice cholestatic 54.75 10.97 16 903108 10027 89715296
Cholelithiasis 54.73 10.97 303 902821 52203 89673120
Tonsillar ulcer 54.65 10.97 36 903088 282 89725041
Epicondylitis 54.50 10.97 95 903029 2499 89722824
Sickle cell anaemia with crisis 54.33 10.97 5 903119 7292 89718031
Insomnia 54.25 10.97 2742 900382 330732 89394591
Apathy 54.24 10.97 21 903103 11019 89714304
Initial insomnia 54.23 10.97 13 903111 9297 89716026
Lacrimation increased 54.16 10.97 118 903006 26944 89698379
Device issue 54.10 10.97 490 902634 29047 89696276
Drug eruption 53.88 10.97 565 902559 34842 89690481
Injection site hypersensitivity 53.36 10.97 96 903028 2591 89722732
Cutaneous T-cell lymphoma 53.30 10.97 73 903051 1547 89723776
Breast cancer stage III 52.93 10.97 1157 901967 83290 89642033
Bronchopulmonary aspergillosis 52.28 10.97 24 903100 11374 89713949
Rheumatic disorder 52.07 10.97 109 903015 3299 89722024
Spinal column injury 51.76 10.97 84 903040 2081 89723242
Dermatitis bullous 51.73 10.97 19 903105 10297 89715026
Bloody discharge 51.67 10.97 86 903038 2177 89723146
Deep vein thrombosis postoperative 51.59 10.97 992 902132 69817 89655506
Injection site haematoma 51.43 10.97 169 902955 6753 89718570
Blood calcium increased 51.38 10.97 28 903096 12030 89713293
Headache 51.37 10.97 7679 895445 855067 88870256
Atrioventricular block first degree 51.35 10.97 11 903113 8500 89716823
Nasal polyps 51.34 10.97 22 903102 10858 89714465
Intervertebral disc protrusion 51.27 10.97 454 902670 26742 89698581
Nocturia 51.23 10.97 19 903105 10236 89715087
Loss of consciousness 51.18 10.97 1037 902087 139201 89586122
Ventricular fibrillation 51.13 10.97 39 903085 14005 89711318
Post transplant lymphoproliferative disorder 51.11 10.97 5 903119 6944 89718379
Treatment noncompliance 50.97 10.97 304 902820 51423 89673900
Hypersomnia 50.86 10.97 85 903039 21446 89703877
Lower limb fracture 50.84 10.97 1157 901967 83856 89641467
Peripheral venous disease 50.77 10.97 1144 901980 82777 89642546
Incorrect dose administered 50.62 10.97 1085 902039 77845 89647478
Autoimmune disorder 50.53 10.97 1059 902065 75685 89649638
Metastases to lung 50.26 10.97 51 903073 15940 89709383
Gastrooesophageal reflux disease 50.21 10.97 1267 901857 165070 89560253
Motor dysfunction 50.14 10.97 71 903053 19159 89706164
Ischaemic stroke 50.09 10.97 90 903034 22076 89703247
Petechiae 49.70 10.97 50 903074 15691 89709632
Adhesion 49.41 10.97 62 903062 1202 89724121
Blood pressure diastolic increased 49.38 10.97 34 903090 12872 89712451
Papilloma viral infection 49.38 10.97 74 903050 1708 89723615
Acute pulmonary oedema 49.14 10.97 17 903107 9563 89715760
Genital haemorrhage 49.05 10.97 13 903111 8689 89716634
Cardiac failure acute 48.97 10.97 29 903095 11900 89713423
Ovarian neoplasm 48.92 10.97 53 903071 872 89724451
Atypical femur fracture 48.90 10.97 4 903120 6417 89718906
Ileostomy closure 48.84 10.97 33 903091 271 89725052
Hypercapnia 48.60 10.97 5 903119 6672 89718651
International normalised ratio fluctuation 48.52 10.97 100 903024 2993 89722330
Hypoalbuminaemia 48.50 10.97 52 903072 15845 89709478
Injection site warmth 47.92 10.97 319 902805 17196 89708127
Polyuria 47.86 10.97 20 903104 10020 89715303
Synovectomy 47.84 10.97 29 903095 193 89725130
Retinitis 47.83 10.97 590 902534 37868 89687455
Drug resistance 47.77 10.97 150 902974 30299 89695024
Faecal calprotectin abnormal 47.60 10.97 28 903096 175 89725148
Ageusia 47.48 10.97 54 903070 16022 89709301
Dislocation of vertebra 47.44 10.97 803 902321 55165 89670158
Hereditary angioedema 47.38 10.97 17 903107 9348 89715975
Loose body in joint 47.37 10.97 64 903060 1338 89723985
Complication of device removal 47.35 10.97 4 903120 6251 89719072
Rectal discharge 47.32 10.97 51 903073 834 89724489
Antibody test positive 47.31 10.97 97 903027 2892 89722431
Personality change 47.27 10.97 8 903116 7313 89718010
Face oedema 47.22 10.97 101 903023 23217 89702106
Cartilage atrophy 47.18 10.97 27 903097 159 89725164
Lower gastrointestinal haemorrhage 46.97 10.97 15 903109 8877 89716446
Rash pustular 46.52 10.97 181 902943 7868 89717455
Limb operation 46.50 10.97 124 903000 4403 89720920
Myopathy 46.14 10.97 40 903084 13478 89711845
Hepatitis cholestatic 46.01 10.97 14 903110 8547 89716776
Lymphoma 45.67 10.97 261 902863 13330 89711993
Oesophagitis 45.66 10.97 63 903061 17186 89708137
Injury associated with device 45.57 10.97 122 903002 4342 89720981
Catatonia 45.50 10.97 4 903120 6052 89719271
Prescribed underdose 45.18 10.97 1022 902102 73997 89651326
Ecchymosis 45.14 10.97 34 903090 12289 89713034
Sleep disorder due to a general medical condition 45.10 10.97 261 902863 44477 89680846
Sensory loss 44.92 10.97 69 903055 18006 89707317
Bradykinesia 44.77 10.97 7 903117 6781 89718542
Antibiotic therapy 44.74 10.97 59 903065 1204 89724119
Pulmonary congestion 44.73 10.97 78 903046 19355 89705968
Skin toxicity 44.69 10.97 7 903117 6772 89718551
Product physical issue 44.60 10.97 3 903121 5657 89719666
Atrioventricular block 44.60 10.97 16 903108 8799 89716524
Erythema multiforme 44.59 10.97 34 903090 12212 89713111
Apnoea 44.48 10.97 19 903105 9395 89715928
Hypernatraemia 44.26 10.97 19 903105 9368 89715955
Foetal exposure during pregnancy 44.25 10.97 249 902875 42726 89682597
Scleritis 44.06 10.97 133 902991 5075 89720248
Tubulointerstitial nephritis 44.01 10.97 119 903005 25224 89700099
Enterocolitis 43.77 10.97 25 903099 10465 89714858
Colonic fistula 43.75 10.97 32 903092 302 89725021
Throat tightness 43.65 10.97 149 902975 29335 89695988
Swelling face 43.55 10.97 560 902564 80792 89644531
Product prescribing error 43.51 10.97 154 902970 29991 89695332
Onychomadesis 43.49 10.97 672 902452 45326 89679997
Stenosis 43.37 10.97 76 903048 2008 89723315
Cholecystitis 43.36 10.97 64 903060 16976 89708347
Road traffic accident 43.26 10.97 1391 901733 106235 89619088
Myocardial infarction 43.16 10.97 769 902355 105203 89620120
Spondyloarthropathy 43.08 10.97 57 903067 1167 89724156
Choking 43.06 10.97 34 903090 11999 89713324
Red cell distribution width decreased 43.02 10.97 78 903046 2118 89723205
Physical disability 42.88 10.97 111 903013 3870 89721453
C-reactive protein decreased 42.80 10.97 54 903070 1053 89724270
Acute graft versus host disease 42.79 10.97 3 903121 5465 89719858
Pelvic pain 42.79 10.97 54 903070 15303 89710020
Thirst 42.65 10.97 60 903064 16235 89709088
Rectal abscess 42.58 10.97 63 903061 1437 89723886
Hepatitis acute 42.57 10.97 28 903096 10859 89714464
Pseudopolyp 42.57 10.97 34 903090 370 89724953
Anuria 42.45 10.97 51 903073 14767 89710556
Hypertriglyceridaemia 42.22 10.97 13 903111 7876 89717447
Sinus disorder 42.09 10.97 188 902936 34259 89691064
Blood creatine increased 42.04 10.97 9 903115 6958 89718365
Concomitant disease aggravated 41.91 10.97 32 903092 11486 89713837
Flatulence 41.88 10.97 241 902883 41126 89684197
Pharyngitis streptococcal 41.71 10.97 243 902881 12499 89712824
Disease susceptibility 41.69 10.97 29 903095 251 89725072
Granulocytopenia 41.68 10.97 7 903117 6434 89718889
Pulmonary tuberculosis 41.42 10.97 124 903000 4710 89720613
Heparin-induced thrombocytopenia 41.33 10.97 3 903121 5309 89720014
Intestinal ulcer 41.31 10.97 66 903058 1613 89723710
Gastrointestinal stoma complication 41.28 10.97 81 903043 2338 89722985
Diplopia 41.24 10.97 147 902977 28567 89696756
Gastrointestinal mucosa hyperaemia 41.04 10.97 26 903098 189 89725134
Spinal stenosis 41.04 10.97 306 902818 17118 89708205
Intestinal operation 41.03 10.97 41 903083 611 89724712
Neutrophil count increased 40.95 10.97 82 903042 19308 89706015
Tension headache 40.87 10.97 12 903112 7497 89717826
Ventricular extrasystoles 40.80 10.97 43 903081 13207 89712116
Colitis ulcerative 40.78 10.97 835 902289 59431 89665892
Low birth weight baby 40.31 10.97 22 903102 9445 89715878
Red blood cell count decreased 40.27 10.97 283 902841 46068 89679255
Aplasia pure red cell 40.22 10.97 3 903121 5191 89720132
Stupor 40.17 10.97 4 903120 5478 89719845
Wheelchair user 40.17 10.97 169 902955 7616 89717707
Inflammatory pain 40.13 10.97 51 903073 1002 89724321
Glycosylated haemoglobin increased 40.04 10.97 58 903066 15504 89709819
Precancerous cells present 40.01 10.97 63 903061 1520 89723803
Supraventricular tachycardia 39.99 10.97 63 903061 16273 89709050
Activated partial thromboplastin time prolonged 39.94 10.97 14 903110 7811 89717512
Atrial tachycardia 39.91 10.97 6 903118 5984 89719339
Poor quality sleep 39.90 10.97 120 903004 24573 89700750
Blood pressure inadequately controlled 39.75 10.97 7 903117 6217 89719106
Drug level decreased 39.62 10.97 197 902927 9533 89715790
Substance abuse 39.47 10.97 4 903120 5402 89719921
Device defective 39.42 10.97 99 903025 3387 89721936
Breast cancer metastatic 39.33 10.97 56 903068 15076 89710247
Pneumonia legionella 39.24 10.97 69 903055 1828 89723495
Gastroenteritis 39.14 10.97 154 902970 29075 89696248
Myocarditis 39.04 10.97 48 903076 13758 89711565
Vascular access complication 39.02 10.97 79 903045 2334 89722989
Coma scale abnormal 38.98 10.97 5 903119 5621 89719702
Ocular sarcoidosis 38.93 10.97 19 903105 76 89725247
Large intestinal ulcer 38.93 10.97 106 903018 3811 89721512
Device occlusion 38.90 10.97 22 903102 9260 89716063
Tonsillitis 38.90 10.97 155 902969 6814 89718509
Postoperative adhesion 38.84 10.97 34 903090 424 89724899
Partial seizures 38.79 10.97 12 903112 7248 89718075
Ketoacidosis 38.70 10.97 5 903119 5590 89719733
Colostomy 38.38 10.97 56 903068 1261 89724062
Sputum discoloured 38.31 10.97 92 903032 20299 89705024
Atrial septal defect 38.30 10.97 17 903107 8217 89717106
Electrocardiogram abnormal 38.26 10.97 28 903096 10270 89715053
Anticipatory anxiety 38.23 10.97 54 903070 1179 89724144
Aspergillus infection 38.21 10.97 31 903093 10792 89714531
Cardiomyopathy 38.09 10.97 91 903033 20115 89705208
Night sweats 38.09 10.97 1608 901516 127158 89598165
Lupus vulgaris 38.01 10.97 646 902478 44413 89680910
Fear 38.00 10.97 67 903057 16555 89708768
Dissociation 37.91 10.97 10 903114 6705 89718618
Medication error 37.82 10.97 604 902520 84048 89641275
Cutaneous leishmaniasis 37.69 10.97 20 903104 99 89725224
Hypovolaemic shock 37.41 10.97 12 903112 7082 89718241
Polyneuropathy 37.34 10.97 86 903038 19255 89706068
Head discomfort 37.19 10.97 66 903058 16267 89709056
Faeces discoloured 37.11 10.97 100 903024 21220 89704103
Anti-cyclic citrullinated peptide antibody 37.10 10.97 425 902699 26796 89698527
Hypokinesia 37.05 10.97 62 903062 15635 89709688
Aspiration 37.03 10.97 62 903062 15631 89709692
Ankle operation 36.90 10.97 59 903065 1443 89723880
Rib fracture 36.87 10.97 137 902987 26298 89699025
Pneumonia bacterial 36.66 10.97 44 903080 12746 89712577
Hypoacusis 36.49 10.97 148 902976 27702 89697621
Psychomotor retardation 36.42 10.97 3 903121 4786 89720537
Intentional product use issue 36.32 10.97 2569 900555 214323 89511000
Vulval disorder 36.09 10.97 55 903069 1289 89724034
Iritis 35.89 10.97 99 903025 3587 89721736
Blood loss anaemia 35.85 10.97 29 903095 10111 89715212
Brain natriuretic peptide increased 35.74 10.97 8 903116 5997 89719326
Mean platelet volume decreased 35.72 10.97 86 903038 2864 89722459
Genital abscess 35.56 10.97 28 903096 298 89725025
Limb injury 35.54 10.97 177 902947 31331 89693992
Osteoporotic fracture 35.52 10.97 116 903008 4620 89720703
Arterial occlusive disease 35.48 10.97 43 903081 12403 89712920
Thrombosis 35.34 10.97 515 902609 72736 89652587
Pharyngitis 35.19 10.97 354 902770 21593 89703730
Therapeutic response unexpected 34.88 10.97 107 903017 21773 89703550
Lymph node tuberculosis 34.80 10.97 42 903082 781 89724542
General symptom 34.77 10.97 258 902866 14410 89710913
Catheter site infection 34.75 10.97 7 903117 5647 89719676
Gait disturbance 34.69 10.97 3031 900093 257465 89467858
Postoperative wound infection 34.63 10.97 241 902883 13185 89712138
Dry throat 34.63 10.97 18 903106 7942 89717381
Metabolic encephalopathy 34.60 10.97 12 903112 6740 89718583
Amyotrophic lateral sclerosis 34.56 10.97 54 903070 1294 89724029
Post procedural complication 34.42 10.97 315 902809 18727 89706596
Middle insomnia 34.39 10.97 72 903052 16679 89708644
Lyme disease 34.34 10.97 107 903017 4155 89721168
Proctectomy 34.33 10.97 23 903101 186 89725137
Pruritus 34.32 10.97 4801 898323 536724 89188599
Pruritus genital 34.27 10.97 3 903121 4555 89720768
Drug tolerance 34.24 10.97 300 902824 17616 89707707
Azotaemia 34.19 10.97 6 903118 5342 89719981
Visual acuity reduced 34.19 10.97 119 903005 23291 89702032
Product monitoring error 34.14 10.97 3 903121 4541 89720782
Procedural intestinal perforation 34.14 10.97 21 903103 144 89725179
Osteonecrosis 34.04 10.97 140 902984 26101 89699222
Blood culture positive 33.98 10.97 5 903119 5067 89720256
Compression fracture 33.83 10.97 23 903101 8766 89716557
Cold sweat 33.81 10.97 55 903069 14026 89711297
Somnambulism 33.81 10.97 10 903114 6218 89719105
Retinal toxicity 33.76 10.97 55 903069 1367 89723956
Atelectasis 33.71 10.97 127 902997 24282 89701041
Bile acid malabsorption 33.61 10.97 26 903098 269 89725054
Aplastic anaemia 33.61 10.97 50 903074 13219 89712104
Neoplasm malignant 33.59 10.97 499 902625 33381 89691942
Skin reaction 33.58 10.97 307 902817 18246 89707077
End stage renal disease 33.57 10.97 22 903102 8549 89716774
Clonus 33.55 10.97 8 903116 5742 89719581
Anger 33.50 10.97 53 903071 13667 89711656
Escherichia bacteraemia 33.42 10.97 8 903116 5727 89719596
Respiratory syncytial virus infection 33.42 10.97 33 903091 10447 89714876
Wrist surgery 33.25 10.97 44 903080 901 89724422
Nasal oedema 33.23 10.97 12 903112 6572 89718751
Gastrointestinal oedema 33.21 10.97 58 903066 1528 89723795
Lipase increased 33.17 10.97 37 903087 11074 89714249
Incorrect drug administration rate 33.09 10.97 6 903118 5217 89720106
Subcutaneous abscess 33.07 10.97 143 902981 6523 89718800
Toxic skin eruption 33.06 10.97 67 903057 15707 89709616
Hepatic cirrhosis 33.02 10.97 845 902279 62408 89662915
Poor venous access 32.93 10.97 93 903031 19434 89705889
IgA nephropathy 32.88 10.97 43 903081 870 89724453
Blood chloride decreased 32.78 10.97 11 903113 6308 89719015
Erythema 32.78 10.97 1909 901215 227337 89497986
Haematocrit decreased 32.74 10.97 263 902861 41569 89683754
Pneumonia viral 32.70 10.97 174 902950 8649 89716674
Subileus 32.68 10.97 95 903029 3549 89721774
Proctocolectomy 32.54 10.97 17 903107 81 89725242
Hyperthyroidism 32.54 10.97 85 903039 18225 89707098
Exposure during pregnancy 32.52 10.97 2779 900345 235631 89489692
Anastomotic ulcer 32.44 10.97 35 903089 573 89724750
Enterococcal infection 32.39 10.97 31 903093 9960 89715363
Pulse absent 32.37 10.97 10 903114 6045 89719278
Hyperreflexia 32.15 10.97 13 903111 6644 89718679
Drug level above therapeutic 32.14 10.97 9 903115 5800 89719523
Kidney transplant rejection 32.05 10.97 5 903119 4852 89720471
Peripheral sensory neuropathy 32.03 10.97 27 903097 9223 89716100
Terminal ileitis 31.95 10.97 50 903074 1200 89724123
Skin laceration 31.87 10.97 142 902982 25893 89699430
Micturition urgency 31.82 10.97 39 903085 11194 89714129
Ear pruritus 31.71 10.97 14 903110 6789 89718534
Quality of life decreased 31.61 10.97 215 902909 11674 89713649
Gastritis 31.54 10.97 265 902859 41488 89683835
Exercise tolerance decreased 31.50 10.97 18 903106 7533 89717790
Female genital tract fistula 31.50 10.97 294 902830 17574 89707749
Incisional hernia 31.49 10.97 62 903062 1794 89723529
Hunger 31.40 10.97 13 903111 6550 89718773
Pyelonephritis 31.37 10.97 108 903016 21208 89704115
Immunosuppression 31.28 10.97 217 902907 11860 89713463
Pseudomonas infection 31.27 10.97 63 903061 14802 89710521
Anorectal disorder 31.08 10.97 65 903059 1966 89723357
Latent tuberculosis 31.06 10.97 82 903042 2894 89722429
Postoperative abscess 31.03 10.97 32 903092 496 89724827
Tricuspid valve incompetence 31.02 10.97 76 903048 16655 89708668
Laryngeal disorder 31.01 10.97 47 903077 1096 89724227
Asphyxia 30.99 10.97 16 903108 7087 89718236
Blood triglycerides increased 30.98 10.97 56 903068 13705 89711618
Wrong product administered 30.95 10.97 19 903105 7646 89717677
Brain herniation 30.95 10.97 3 903121 4197 89721126
Eye pain 30.86 10.97 286 902838 43882 89681441
Neck mass 30.86 10.97 97 903027 3785 89721538
Amylase increased 30.75 10.97 16 903108 7056 89718267
Dizziness postural 30.65 10.97 27 903097 9026 89716297
Euphoric mood 30.64 10.97 8 903116 5401 89719922
Product prescribing issue 30.56 10.97 21 903103 7958 89717365
Histone antibody positive 30.54 10.97 21 903103 178 89725145
Feeling hot 30.53 10.97 570 902554 77438 89647885
Toothache 30.49 10.97 116 903008 22114 89703209
Cholangitis sclerosing 30.46 10.97 68 903056 2153 89723170
Thrombotic thrombocytopenic purpura 30.37 10.97 3 903121 4135 89721188
Therapeutic response decreased 30.37 10.97 1137 901987 88592 89636731
Retching 30.32 10.97 94 903030 19065 89706258
Hypogammaglobulinaemia 30.30 10.97 37 903087 10637 89714686
Neutrophil count abnormal 30.28 10.97 3 903121 4125 89721198
Therapy partial responder 30.25 10.97 115 903009 21928 89703395
Mental disorder 30.24 10.97 193 902931 32125 89693198
Oral herpes 29.96 10.97 203 902921 33321 89692002
C-reactive protein 29.94 10.97 459 902665 30908 89694415
Spinal operation 29.91 10.97 189 902935 10007 89715316
Angina unstable 29.84 10.97 17 903107 7126 89718197
Sensitivity to weather change 29.83 10.97 171 902953 8743 89716580
Failure to thrive 29.81 10.97 24 903100 8387 89716936
Blood glucose fluctuation 29.80 10.97 7 903117 5076 89720247
Skin abrasion 29.77 10.97 41 903083 11194 89714129
Pseudopolyposis 29.70 10.97 11 903113 17 89725306
Aphonia 29.69 10.97 48 903076 12271 89713052
Enterostomy 29.68 10.97 19 903105 141 89725182
Non-cardiac chest pain 29.53 10.97 15 903109 6706 89718617
Influenza like illness 29.43 10.97 596 902528 80015 89645308
Cancer pain 29.33 10.97 3 903121 4022 89721301
Stridor 29.32 10.97 6 903118 4787 89720536
Methaemoglobinaemia 29.24 10.97 3 903121 4012 89721311
Muscle strain 29.20 10.97 32 903092 9655 89715668
Breast cancer 29.19 10.97 722 902402 53039 89672284
Hyperthermia 29.15 10.97 36 903088 10299 89715024
Ligament sprain 28.93 10.97 64 903060 14535 89710788
Obsessive-compulsive disorder 28.91 10.97 5 903119 4499 89720824
Bone density decreased 28.89 10.97 282 902842 17063 89708260
Cutaneous vasculitis 28.84 10.97 145 902979 7048 89718275
Prolonged labour 28.69 10.97 33 903091 582 89724741
Respiratory tract congestion 28.66 10.97 158 902966 27252 89698071
Sleep terror 28.56 10.97 5 903119 4459 89720864
Large intestinal obstruction 28.55 10.97 75 903049 2639 89722684
Intestinal perforation 28.41 10.97 236 902888 13645 89711678
Pulmonary arterial pressure increased 28.33 10.97 3 903121 3913 89721410
Rhinovirus infection 28.23 10.97 12 903112 5951 89719372
Anosmia 28.10 10.97 34 903090 9814 89715509
Lower respiratory tract infection viral 27.85 10.97 41 903083 931 89724392
Blood magnesium decreased 27.77 10.97 73 903051 15620 89709703
Iridocyclitis 27.75 10.97 90 903034 3571 89721752
Injection site bruising 27.66 10.97 700 902424 51607 89673716
Vasculitic rash 27.52 10.97 50 903074 1360 89723963
Influenza 27.50 10.97 1121 902003 138143 89587180
Lymphoedema 27.49 10.97 60 903064 13693 89711630
Blood phosphorus decreased 27.48 10.97 8 903116 5026 89720297
Post-traumatic stress disorder 27.47 10.97 17 903107 6811 89718512
Sexual dysfunction 27.42 10.97 7 903117 4797 89720526
Spondylitis 27.41 10.97 238 902886 13940 89711383
Peptic ulcer haemorrhage 27.40 10.97 44 903080 1080 89724243
Periorbital swelling 27.36 10.97 7 903117 4791 89720532
Ventricular arrhythmia 27.29 10.97 5 903119 4316 89721007
Multiple fractures 27.28 10.97 176 902948 9386 89715937
Gout 27.19 10.97 82 903042 16777 89708546
Tumour marker increased 26.99 10.97 12 903112 5795 89719528
Sudden death 26.77 10.97 42 903082 10867 89714456
Abortion spontaneous 26.73 10.97 717 902407 53339 89671984
Exposure to communicable disease 26.72 10.97 33 903091 629 89724694
Panic reaction 26.68 10.97 7 903117 4710 89720613
Respiration abnormal 26.65 10.97 24 903100 7939 89717384
Application site pruritus 26.64 10.97 5 903119 4242 89721081
Chronic recurrent multifocal osteomyelitis 26.64 10.97 13 903111 52 89725271
Ankle arthroplasty 26.55 10.97 75 903049 2756 89722567
Injection site oedema 26.49 10.97 56 903068 1707 89723616
Granuloma 26.45 10.97 127 902997 6058 89719265
Hyperphosphataemia 26.45 10.97 3 903121 3708 89721615
Endophthalmitis 26.41 10.97 7 903117 4678 89720645
Incorrect product administration duration 26.38 10.97 101 903023 19221 89706102
Atrioventricular block second degree 26.36 10.97 6 903118 4446 89720877
Epigastric discomfort 26.31 10.97 22 903102 7546 89717777
Colitis 26.31 10.97 897 902227 69045 89656278
Galactorrhoea 26.30 10.97 7 903117 4665 89720658
Malignant melanoma in situ 26.29 10.97 40 903084 936 89724387
Maternal exposure timing unspecified 26.28 10.97 341 902783 22142 89703181
Functional gastrointestinal disorder 26.20 10.97 110 903014 4952 89720371
DNA antibody positive 26.20 10.97 25 903099 351 89724972
Renal function test abnormal 26.14 10.97 20 903104 7171 89718152
Amenorrhoea 26.13 10.97 48 903076 11674 89713649
Disturbance in social behaviour 26.13 10.97 5 903119 4183 89721140
Infiltration anaesthesia 26.09 10.97 19 903105 178 89725145
Magnetic resonance imaging thoracic abnormal 26.07 10.97 10 903114 18 89725305
Catheter site haemorrhage 26.05 10.97 3 903121 3665 89721658
Tonsillar hypertrophy 26.04 10.97 44 903080 1128 89724195
Decreased interest 25.97 10.97 6 903118 4401 89720922
Protein urine present 25.93 10.97 19 903105 6965 89718358
Infected dermal cyst 25.93 10.97 28 903096 459 89724864
Eyelid oedema 25.91 10.97 47 903077 11487 89713836
Haemophagocytic lymphohistiocytosis 25.80 10.97 74 903050 15385 89709938
Diffuse vasculitis 25.73 10.97 10 903114 19 89725304
Haemoglobin increased 25.70 10.97 22 903102 7459 89717864
Accident 25.68 10.97 137 902987 6817 89718506
Meniscus injury 25.62 10.97 155 902969 8082 89717241
Gliosis 25.55 10.97 28 903096 467 89724856
Post procedural sepsis 25.53 10.97 25 903099 363 89724960
Sinus node dysfunction 25.44 10.97 11 903113 5401 89719922
Application site erythema 25.43 10.97 10 903114 5198 89720125
Ventricular septal defect 25.41 10.97 11 903113 5396 89719927
Granulomatous lymphadenitis 25.39 10.97 20 903104 213 89725110
Mucous stools 25.33 10.97 112 903012 5159 89720164
Subacute inflammatory demyelinating polyneuropathy 25.33 10.97 7 903117 0 89725323
Abscess rupture 25.33 10.97 23 903101 302 89725021
Systemic infection 25.32 10.97 8 903116 4767 89720556
Electroencephalogram abnormal 25.32 10.97 5 903119 4091 89721232
Device malfunction 25.30 10.97 320 902804 20657 89704666
Intestinal mass 25.24 10.97 42 903082 1063 89724260
Lymphadenopathy 25.23 10.97 616 902508 45159 89680164
Purpura 25.21 10.97 70 903054 14708 89710615
Nephropathy 25.19 10.97 33 903091 9202 89716121
Skin fissures 25.17 10.97 114 903010 20695 89704628
Peritonitis bacterial 25.14 10.97 10 903114 5161 89720162
Allergic respiratory symptom 25.12 10.97 18 903106 164 89725159
Myxoid liposarcoma 25.12 10.97 8 903116 5 89725318
Metastasis 25.08 10.97 15 903109 6122 89719201
Pseudomonal sepsis 25.07 10.97 6 903118 4296 89721027
Drug dependence 25.02 10.97 180 902944 29147 89696176
Hypertonia 25.01 10.97 10 903114 5145 89720178
Intestinal ischaemia 25.00 10.97 31 903093 8852 89716471
Product residue present 24.98 10.97 6 903118 4285 89721038
Performance status decreased 24.88 10.97 6 903118 4274 89721049
Ventricular hypokinesia 24.88 10.97 11 903113 5330 89719993
Blood uric acid increased 24.87 10.97 24 903100 7680 89717643
Ectopic pregnancy 24.86 10.97 80 903044 3161 89722162
Secretion discharge 24.82 10.97 255 902869 15641 89709682
Post procedural infection 24.69 10.97 192 902932 10882 89714441
Hepatic necrosis 24.58 10.97 17 903107 6421 89718902
Colitis ischaemic 24.57 10.97 54 903070 12292 89713031
Disease recurrence 24.54 10.97 248 902876 37405 89687918
Short-bowel syndrome 24.53 10.97 32 903092 646 89724677
Drug screen positive 24.49 10.97 4 903120 3753 89721570
B-cell lymphoma 24.43 10.97 86 903038 3560 89721763
Nail psoriasis 24.42 10.97 33 903091 690 89724633
Facial pain 24.35 10.97 60 903064 13122 89712201
Post procedural inflammation 24.33 10.97 16 903108 125 89725198
Metastases to meninges 24.30 10.97 4 903120 3731 89721592
Supraventricular extrasystoles 24.22 10.97 11 903113 5246 89720077
Intestinal polyp 24.20 10.97 50 903074 1499 89723824
Enterovesical fistula 24.19 10.97 32 903092 655 89724668
Caesarean section 24.16 10.97 99 903025 18478 89706845
Lip ulceration 24.16 10.97 62 903062 2150 89723173
Chronic cutaneous lupus erythematosus 24.05 10.97 36 903088 830 89724493
Respiratory alkalosis 24.05 10.97 3 903121 3445 89721878
Hyperuricaemia 24.03 10.97 19 903105 6700 89718623
Cellulitis 23.86 10.97 710 902414 90627 89634696
Blood glucose abnormal 23.81 10.97 36 903088 9456 89715867
Injection site nodule 23.78 10.97 98 903026 4375 89720948
Ammonia increased 23.66 10.97 10 903114 4976 89720347
Colon dysplasia 23.62 10.97 16 903108 132 89725191
Peripheral coldness 23.55 10.97 66 903058 13826 89711497
Nail operation 23.54 10.97 56 903068 1850 89723473
Histoplasmosis disseminated 23.54 10.97 63 903061 2242 89723081
Paronychia 23.53 10.97 27 903097 7979 89717344
Diastolic dysfunction 23.49 10.97 23 903101 7310 89718013
Acute coronary syndrome 23.46 10.97 45 903079 10768 89714555
Juvenile idiopathic arthritis 23.45 10.97 90 903034 3887 89721436
Lung opacity 23.45 10.97 16 903108 6086 89719237
Muscle tightness 23.42 10.97 63 903061 13376 89711947
Stoma closure 23.29 10.97 18 903106 186 89725137
Metabolic disorder 23.28 10.97 24 903100 7446 89717877
Staphylococcal bacteraemia 23.27 10.97 24 903100 7445 89717878
Hydronephrosis 23.26 10.97 56 903068 12346 89712977
Bronchial secretion retention 23.23 10.97 4 903120 3611 89721712
Obliterative bronchiolitis 23.19 10.97 69 903055 2612 89722711
Blindness 23.18 10.97 162 902962 26406 89698917
Ocular hyperaemia 23.12 10.97 220 902904 33578 89691745
Joint warmth 23.11 10.97 53 903071 1709 89723614
Gastric disorder 23.07 10.97 464 902660 32920 89692403
Pulmonary function test decreased 23.01 10.97 8 903116 4486 89720837
Hypoaesthesia oral 22.98 10.97 79 903045 15521 89709802
Neck surgery 22.95 10.97 58 903066 1992 89723331
Pneumocystis jirovecii pneumonia 22.93 10.97 124 903000 21492 89703831
Neuroendocrine carcinoma of the skin 22.88 10.97 35 903089 823 89724500
Eye disorder 22.85 10.97 392 902732 26998 89698325
Eye movement disorder 22.83 10.97 17 903107 6181 89719142
Benign hepatic neoplasm 22.79 10.97 13 903111 76 89725247
Bundle branch block right 22.75 10.97 13 903111 5440 89719883
Injection site extravasation 22.74 10.97 161 902963 8858 89716465
Enteropathic spondylitis 22.73 10.97 11 903113 43 89725280
Myelodysplastic syndrome 22.68 10.97 119 903005 20784 89704539
Small intestine operation 22.62 10.97 10 903114 30 89725293
Oligohydramnios 22.59 10.97 23 903101 7178 89718145
Gastrointestinal anastomotic stenosis 22.56 10.97 8 903116 10 89725313
Neck deformity 22.52 10.97 60 903064 2129 89723194
Perineal rash 22.52 10.97 13 903111 78 89725245
Drug level abnormal 22.51 10.97 21 903103 286 89725037
Left ventricular dysfunction 22.49 10.97 73 903051 14596 89710727
Vaginal haemorrhage 22.49 10.97 201 902923 31070 89694253
Bronchopulmonary aspergillosis allergic 22.45 10.97 5 903119 3761 89721562
Aplasia 22.42 10.97 6 903118 3985 89721338
Respiratory rate decreased 22.36 10.97 6 903118 3977 89721346
Muscular weakness 22.34 10.97 1764 901360 204902 89520421
Candida infection 22.32 10.97 224 902900 33833 89691490
Paternal exposure during pregnancy 22.27 10.97 22 903102 323 89725000
Histoplasmosis 22.26 10.97 60 903064 2144 89723179
Wrist deformity 22.24 10.97 77 903047 3161 89722162
Loss of therapeutic response 22.21 10.97 52 903072 1700 89723623
Blood thyroid stimulating hormone decreased 22.12 10.97 15 903109 5725 89719598
Refusal of treatment by patient 22.11 10.97 15 903109 5723 89719600
Deafness 22.08 10.97 331 902793 22183 89703140
Soft tissue disorder 22.03 10.97 93 903031 4197 89721126
Scleroderma 22.02 10.97 18 903106 6243 89719080
Dermatitis contact 22.02 10.97 66 903058 13529 89711794
Wrong patient received product 22.01 10.97 4 903120 3473 89721850
Self-medication 21.98 10.97 3 903121 3217 89722106
Local reaction 21.98 10.97 33 903091 763 89724560
Type I hypersensitivity 21.96 10.97 7 903117 4148 89721175
Patent ductus arteriosus 21.94 10.97 9 903115 4560 89720763
Hyperpyrexia 21.88 10.97 10 903114 4751 89720572
Cardiac murmur 21.81 10.97 100 903024 18094 89707229
Brain injury 21.78 10.97 27 903097 7711 89717612
Torus fracture 21.71 10.97 16 903108 153 89725170
Intra-abdominal fluid collection 21.64 10.97 70 903054 2774 89722549
Rectal cancer 21.62 10.97 61 903063 2240 89723083
Decreased activity 21.60 10.97 30 903094 8162 89717161
Injection site vesicles 21.53 10.97 91 903033 4109 89721214
Anaplastic large-cell lymphoma 21.51 10.97 13 903111 86 89725237
Panic attack 21.45 10.97 164 902960 26201 89699122
Acute disseminated encephalomyelitis 21.45 10.97 19 903105 241 89725082
Bone marrow oedema 21.44 10.97 46 903078 1417 89723906
Cerebral haematoma 21.34 10.97 8 903116 4281 89721042
Rebound effect 21.30 10.97 38 903086 9346 89715977
Hair texture abnormal 21.29 10.97 10 903114 4677 89720646
Postoperative wound complication 21.29 10.97 40 903084 1117 89724206
Embolic stroke 21.28 10.97 7 903117 4065 89721258
Abortion incomplete 21.26 10.97 3 903121 3137 89722186
Ventricular hypertrophy 21.26 10.97 4 903120 3387 89721936
Intestinal sepsis 21.23 10.97 21 903103 309 89725014
Arthritis bacterial 21.22 10.97 137 902987 7308 89718015
Thinking abnormal 21.20 10.97 54 903070 11678 89713645
Prosthesis user 21.20 10.97 12 903112 69 89725254
Embolism venous 21.19 10.97 5 903119 3615 89721708
Exposure via skin contact 21.16 10.97 47 903077 10658 89714665
Food intolerance 21.15 10.97 86 903038 3816 89721507
Abdominal lymphadenopathy 21.10 10.97 37 903087 978 89724345
Vaginal fistula 21.10 10.97 28 903096 575 89724748
Eye swelling 21.09 10.97 189 902935 29197 89696126
Pharyngeal swelling 21.04 10.97 42 903082 9902 89715421
Crohn's disease 21.03 10.97 100 903024 4751 89720572
Short stature 20.96 10.97 38 903086 1032 89724291
Fungaemia 20.90 10.97 4 903120 3346 89721977
Gastrointestinal anastomotic leak 20.89 10.97 19 903105 250 89725073
Paradoxical drug reaction 20.89 10.97 113 903011 5653 89719670
Renal pain 20.88 10.97 28 903096 7731 89717592
Muscle haemorrhage 20.86 10.97 4 903120 3342 89721981
Mitral valve incompetence 20.83 10.97 135 902989 22389 89702934
Small for dates baby 20.80 10.97 12 903112 4995 89720328
Blood immunoglobulin E increased 20.79 10.97 9 903115 4416 89720907
Bladder disorder 20.71 10.97 48 903076 10724 89714599
Thrombosis in device 20.67 10.97 3 903121 3072 89722251
Transaminases increased 20.66 10.97 254 902870 36938 89688385
Computerised tomogram abdomen abnormal 20.60 10.97 9 903115 26 89725297
Device use error 20.53 10.97 25 903099 7196 89718127
Unevaluable event 20.53 10.97 703 902421 54145 89671178
Serum ferritin decreased 20.49 10.97 65 903059 2549 89722774
Memory impairment 20.48 10.97 1689 901435 195555 89529768
Petit mal epilepsy 20.43 10.97 12 903112 4946 89720377
Catheterisation cardiac 20.41 10.97 12 903112 4944 89720379
Foetal growth restriction 20.38 10.97 39 903085 9341 89715982
Myocardial ischaemia 20.32 10.97 70 903054 13744 89711579
Purulent discharge 20.31 10.97 107 903017 5298 89720025
Congestive hepatopathy 20.30 10.97 3 903121 3030 89722293
Skin hyperpigmentation 20.25 10.97 23 903101 6828 89718495
Ventricular dysfunction 20.24 10.97 6 903118 3725 89721598
Dyshidrotic eczema 20.23 10.97 31 903093 730 89724593
Hiccups 20.23 10.97 3 903121 3023 89722300
Premature labour 20.21 10.97 67 903057 13309 89712014
Hypoventilation 20.20 10.97 14 903110 5282 89720041
Pathogen resistance 20.15 10.97 31 903093 8084 89717239
Disability assessment scale score increased 20.12 10.97 7 903117 3924 89721399
Injection site mass 20.12 10.97 133 902991 21957 89703366
White blood cells urine positive 20.11 10.97 21 903103 6477 89718846
Device breakage 20.10 10.97 72 903052 13972 89711351
Haemorrhagic stroke 20.09 10.97 21 903103 6475 89718848
Tongue oedema 20.04 10.97 15 903109 5439 89719884
Lumbosacral plexopathy 20.03 10.97 13 903111 99 89725224
Ileus paralytic 19.99 10.97 13 903111 5072 89720251
Injection site inflammation 19.97 10.97 94 903030 4447 89720876
Perirectal abscess 19.89 10.97 35 903089 928 89724395
Major depression 19.88 10.97 44 903080 9991 89715332
Vulvovaginal erythema 19.86 10.97 27 903097 568 89724755
Seronegative arthritis 19.85 10.97 273 902851 17961 89707362
Pleuropericarditis 19.84 10.97 21 903103 336 89724987
Cardiomegaly 19.84 10.97 109 903015 18816 89706507
BK virus infection 19.82 10.97 10 903114 4488 89720835
Proctitis 19.80 10.97 236 902888 15023 89710300
Temperature intolerance 19.77 10.97 58 903066 11972 89713351
Defaecation urgency 19.76 10.97 118 903006 6124 89719199
Extra dose administered 19.74 10.97 38 903086 9080 89716243
Klebsiella infection 19.71 10.97 46 903078 10251 89715072
Cholelithiasis obstructive 19.70 10.97 8 903116 18 89725305
Blood test abnormal 19.67 10.97 125 902999 20827 89704496
Thermal burn 19.66 10.97 23 903101 6739 89718584
Clostridium test positive 19.66 10.97 15 903109 5386 89719937
Renal tubular disorder 19.65 10.97 4 903120 3203 89722120
Intestinal fistula infection 19.63 10.97 7 903117 9 89725314
SAPHO syndrome 19.59 10.97 14 903110 127 89725196
Cutaneous lupus erythematosus 19.58 10.97 72 903052 3046 89722277
Pulmonary haemorrhage 19.52 10.97 31 903093 7982 89717341
Desmoid tumour 19.52 10.97 13 903111 104 89725219
Jejunal stenosis 19.47 10.97 11 903113 63 89725260
Blood prolactin increased 19.45 10.97 6 903118 3631 89721692
Brachiocephalic artery stenosis 19.45 10.97 9 903115 31 89725292
International normalised ratio abnormal 19.42 10.97 7 903117 3838 89721485
Circumstance or information capable of leading to device use error 19.36 10.97 17 903107 213 89725110
Mammoplasty 19.35 10.97 30 903094 714 89724609
Conjunctival hyperaemia 19.32 10.97 4 903120 3165 89722158
Adenovirus infection 19.31 10.97 11 903113 4611 89720712
Pneumonia fungal 19.30 10.97 25 903099 7006 89718317
Pulmonary mass 19.25 10.97 398 902726 28374 89696949
Genital cyst 19.25 10.97 10 903114 47 89725276
Ocular discomfort 19.25 10.97 21 903103 6349 89718974
Steroid dependence 19.25 10.97 58 903066 2211 89723112
Brain death 19.18 10.97 8 903116 4013 89721310
Low density lipoprotein increased 19.02 10.97 32 903092 8053 89717270
Spinal meningioma benign 19.02 10.97 13 903111 109 89725214
Thyroid neoplasm 18.99 10.97 85 903039 3936 89721387
Jugular vein thrombosis 18.99 10.97 6 903118 3575 89721748
Tendonitis 18.98 10.97 309 902815 21063 89704260
Hodgkin's disease 18.96 10.97 30 903094 727 89724596
Blood urine present 18.95 10.97 98 903026 17180 89708143
Mood altered 18.94 10.97 97 903027 17047 89708276
Autoimmune haemolytic anaemia 18.91 10.97 17 903107 5628 89719695
Respiratory tract infection 18.91 10.97 446 902678 58632 89666691
Dermal cyst 18.90 10.97 56 903068 2115 89723208
Hernia 18.86 10.97 221 902903 14010 89711313
Ileocolostomy 18.83 10.97 9 903115 34 89725289
Therapeutic product effect variable 18.78 10.97 45 903079 1494 89723829
Infestation 18.77 10.97 10 903114 50 89725273
Drooling 18.73 10.97 11 903113 4535 89720788
Walking aid user 18.73 10.97 475 902649 35031 89690292
Device deployment issue 18.69 10.97 13 903111 4896 89720427
Parinaud syndrome 18.69 10.97 6 903118 4 89725319
Diffuse alopecia 18.62 10.97 39 903085 1181 89724142
Cystitis 18.59 10.97 514 902610 66204 89659119
Cartilage injury 18.58 10.97 55 903069 2076 89723247
Femoral neck fracture 18.57 10.97 47 903077 10186 89715137
Hyperlactacidaemia 18.52 10.97 9 903115 4127 89721196
Adenocarcinoma of the cervix 18.49 10.97 17 903107 227 89725096
Anal fissure 18.48 10.97 104 903020 5281 89720042
Reversible cerebral vasoconstriction syndrome 18.48 10.97 9 903115 4121 89721202
Gastrointestinal infection 18.46 10.97 179 902945 10811 89714512
Contusion 18.45 10.97 2813 900311 248403 89476920
Proteinuria 18.42 10.97 146 902978 23145 89702178
Parakeratosis 18.42 10.97 20 903104 330 89724993
Hyperventilation 18.39 10.97 24 903100 6704 89718619
Cerebral ischaemia 18.34 10.97 27 903097 7169 89718154
Neurological decompensation 18.33 10.97 6 903118 3495 89721828
Erythema of eyelid 18.32 10.97 5 903119 3278 89722045
Extremity contracture 18.20 10.97 40 903084 1253 89724070
Carbohydrate antigen 125 increased 18.18 10.97 5 903119 3261 89722062
Gingival swelling 18.15 10.97 14 903110 4999 89720324
Spinal cord infection 18.11 10.97 29 903095 710 89724613
Electrocardiogram T wave inversion 18.10 10.97 7 903117 3676 89721647
Tension 18.10 10.97 7 903117 3675 89721648
Infection transmission via personal contact 18.09 10.97 5 903119 0 89725323
Psoriasis area severity index increased 18.08 10.97 15 903109 173 89725150
Arteriosclerosis 18.07 10.97 52 903072 10801 89714522
Orthopnoea 18.06 10.97 25 903099 6810 89718513
Bone abscess 18.06 10.97 23 903101 453 89724870
Overwork 18.02 10.97 10 903114 55 89725268
Heavy exposure to ultraviolet light 18.01 10.97 12 903112 96 89725227
Carotid artery occlusion 17.98 10.97 22 903102 6320 89719003
Hepatomegaly 17.98 10.97 70 903054 13256 89712067
Immune thrombocytopenia 17.98 10.97 70 903054 13256 89712067
Breast cancer recurrent 17.93 10.97 17 903107 5486 89719837
Vitamin D deficiency 17.92 10.97 102 903022 17454 89707869
Capillary leak syndrome 17.92 10.97 3 903121 2764 89722559
Blepharospasm 17.91 10.97 699 902425 54746 89670577
Hypermobility syndrome 17.83 10.97 32 903092 862 89724461
Skin lesion 17.73 10.97 493 902631 36872 89688451
Diabetes insipidus 17.73 10.97 5 903119 3207 89722116
Product availability issue 17.70 10.97 29 903095 7375 89717948
Rash morbilliform 17.69 10.97 9 903115 4020 89721303
Ankle deformity 17.68 10.97 23 903101 463 89724860
Pneumothorax 17.66 10.97 115 903009 19052 89706271
Occult blood positive 17.65 10.97 9 903115 4014 89721309
Autoimmune pancreatitis 17.64 10.97 20 903104 347 89724976
Laryngitis 17.63 10.97 645 902479 50108 89675215
Mean cell haemoglobin decreased 17.61 10.97 107 903017 5588 89719735
Acute graft versus host disease in skin 17.58 10.97 13 903111 4743 89720580
N-terminal prohormone brain natriuretic peptide increased 17.52 10.97 4 903120 2958 89722365
Urticaria 17.51 10.97 3452 899672 309282 89416041
Mean cell volume decreased 17.48 10.97 90 903034 4416 89720907
Blood sodium increased 17.47 10.97 5 903119 3177 89722146
Pachymeningitis 17.41 10.97 17 903107 246 89725077
Stress at work 17.36 10.97 41 903083 1348 89723975
Bruxism 17.36 10.97 11 903113 4352 89720971
International normalised ratio decreased 17.35 10.97 13 903111 4711 89720612
Exposed bone in jaw 17.21 10.97 4 903120 2922 89722401
Endotracheal intubation 17.20 10.97 6 903118 3358 89721965
Thyroiditis subacute 17.20 10.97 20 903104 357 89724966
Internal haemorrhage 17.20 10.97 22 903102 6198 89719125
Lichen myxoedematosus 17.20 10.97 8 903116 28 89725295
Axial spondyloarthritis 17.19 10.97 26 903098 605 89724718
Oesophageal spasm 17.18 10.97 6 903118 3355 89721968
Jaw disorder 17.16 10.97 18 903106 5541 89719782
Stoma obstruction 17.15 10.97 16 903108 218 89725105
Injection site laceration 17.05 10.97 12 903112 106 89725217
Large intestine anastomosis 16.99 10.97 8 903116 29 89725294
Bone density abnormal 16.98 10.97 84 903040 4056 89721267
Ear injury 16.97 10.97 19 903105 325 89724998
Urine abnormality 16.96 10.97 32 903092 7705 89717618
Blood bicarbonate decreased 16.95 10.97 5 903119 3114 89722209
Blood immunoglobulin G decreased 16.94 10.97 7 903117 3531 89721792
Stoma creation 16.93 10.97 13 903111 133 89725190
Language disorder 16.90 10.97 3 903121 2649 89722674
Pyoderma 16.89 10.97 24 903100 527 89724796
Pulmonary alveolar haemorrhage 16.81 10.97 21 903103 5977 89719346
Oxygen therapy 16.80 10.97 5 903119 3097 89722226
Synovial fluid analysis 16.80 10.97 64 903060 2754 89722569
Groin pain 16.79 10.97 191 902933 12022 89713301
Iris adhesions 16.78 10.97 21 903103 406 89724917
Lip oedema 16.74 10.97 13 903111 4626 89720697
Ileocolectomy 16.69 10.97 10 903114 65 89725258
Axillary mass 16.67 10.97 26 903098 622 89724701
Nystagmus 16.64 10.97 29 903095 7198 89718125
Eyelid ptosis 16.63 10.97 41 903083 8965 89716358
Decubitus ulcer 16.62 10.97 61 903063 11752 89713571
Haematocrit increased 16.60 10.97 5 903119 3073 89722250
Dental caries 16.60 10.97 58 903066 11339 89713984
Multiple system atrophy 16.58 10.97 15 903109 196 89725127
Diabetic eye disease 16.56 10.97 14 903110 166 89725157
Blood pressure abnormal 16.55 10.97 121 903003 19524 89705799
Urine leukocyte esterase positive 16.53 10.97 6 903118 3276 89722047
Economic problem 16.52 10.97 6 903118 3275 89722048
Unwanted pregnancy 16.52 10.97 12 903112 112 89725211
Thyroid operation 16.52 10.97 15 903109 197 89725126
Duodenal ulcer 16.48 10.97 45 903079 9507 89715816
Cholecystitis acute 16.45 10.97 44 903080 9360 89715963
Depressive symptom 16.44 10.97 17 903107 5268 89720055
Biliary dyskinesia 16.43 10.97 3 903121 2596 89722727
Bronchitis 16.41 10.97 1306 901818 151621 89573702
Peritoneal tuberculosis 16.40 10.97 24 903100 542 89724781
Cachexia 16.39 10.97 27 903097 6851 89718472
Polydipsia 16.38 10.97 11 903113 4220 89721103
Unintended pregnancy 16.38 10.97 32 903092 7605 89717718
Graft versus host disease in skin 16.34 10.97 9 903115 3844 89721479
Chronic disease 16.33 10.97 15 903109 200 89725123
Hyperkaliuria 16.32 10.97 10 903114 68 89725255
Infected fistula 16.25 10.97 16 903108 234 89725089
Allergy to vaccine 16.25 10.97 16 903108 234 89725089
Autonomic nervous system imbalance 16.24 10.97 7 903117 3443 89721880
Groin abscess 16.24 10.97 37 903087 1188 89724135
Product quality issue 16.20 10.97 636 902488 78689 89646634
Anorectal ulcer 16.14 10.97 9 903115 50 89725273
Subcorneal pustular dermatosis 16.14 10.97 9 903115 50 89725273
Culture urine positive 16.13 10.97 9 903115 3816 89721507
Paranasal sinus discomfort 16.12 10.97 23 903101 6187 89719136
Vulvovaginal dryness 16.09 10.97 7 903117 3424 89721899
Granulomatous rosacea 16.08 10.97 7 903117 20 89725303
Ischaemic hepatitis 16.07 10.97 4 903120 2789 89722534
Inadequate analgesia 16.06 10.97 6 903118 3218 89722105
Metastases to lymph nodes 16.03 10.97 61 903063 11628 89713695
Genital ulceration 16.02 10.97 34 903090 1039 89724284
Enterocolonic fistula 16.00 10.97 9 903115 51 89725272
Cervix carcinoma stage 0 15.98 10.97 24 903100 555 89724768
Gingival disorder 15.97 10.97 10 903114 3981 89721342
Staphylococcal abscess 15.96 10.97 29 903095 789 89724534
Hypertonic bladder 15.92 10.97 12 903112 4336 89720987
Lung adenocarcinoma stage IV 15.91 10.97 21 903103 429 89724894
Enteritis 15.84 10.97 165 902959 10156 89715167
Intervertebral disc calcification 15.77 10.97 5 903119 3 89725320
Serum ferritin increased 15.77 10.97 31 903093 7350 89717973
Autoantibody positive 15.75 10.97 10 903114 73 89725250
Non-consummation 15.73 10.97 9 903115 53 89725270
Malignant pleural effusion 15.66 10.97 5 903119 2959 89722364
Trigeminal neuralgia 15.65 10.97 11 903113 4120 89721203
Cerebral atrophy 15.58 10.97 20 903104 5626 89719697
Benign neoplasm 15.52 10.97 33 903091 1010 89724313
Skin discolouration 15.48 10.97 330 902794 43985 89681338
Hepatitis B virus test positive 15.47 10.97 15 903109 215 89725108
Demyelinating polyneuropathy 15.42 10.97 31 903093 911 89724412
Hydrocephalus 15.40 10.97 23 903101 6071 89719252
Neutrophilia 15.40 10.97 21 903103 5757 89719566
Blood albumin decreased 15.39 10.97 101 903023 16702 89708621
Pneumothorax traumatic 15.39 10.97 13 903111 154 89725169
Cutaneous sarcoidosis 15.37 10.97 21 903103 444 89724879
Prurigo 15.35 10.97 31 903093 914 89724409
Cholecystectomy 15.34 10.97 182 902942 11573 89713750
Bilirubin conjugated increased 15.30 10.97 6 903118 3124 89722199
Tendon rupture 15.26 10.97 150 902974 9093 89716230
Tracheobronchitis bacterial 15.24 10.97 6 903118 12 89725311
Rectal tube insertion 15.24 10.97 6 903118 12 89725311
Pre-existing condition improved 15.22 10.97 44 903080 9125 89716198
Disseminated large cell lymphoma 15.20 10.97 9 903115 57 89725266
Hereditary motor and sensory neuropathy 15.20 10.97 11 903113 102 89725221
Electrocardiogram T wave abnormal 15.18 10.97 4 903120 2684 89722639
Gastric operation 15.16 10.97 19 903105 368 89724955
Henoch-Schonlein purpura 15.16 10.97 43 903081 1584 89723739
Localised infection 15.14 10.97 440 902684 33122 89692201
Skin haemorrhage 15.13 10.97 138 902986 21242 89704081
Anxiety disorder 15.13 10.97 16 903108 4906 89720417
Intracranial pressure increased 15.08 10.97 28 903096 6783 89718540
Acquired claw toe 15.05 10.97 14 903110 190 89725133
Post procedural fistula 15.04 10.97 19 903105 371 89724952
Paralysis 15.03 10.97 61 903063 11417 89713906
Clinically isolated syndrome 15.01 10.97 8 903116 40 89725283
Optic neuritis 14.99 10.97 155 902969 9523 89715800
Myelitis transverse 14.97 10.97 41 903083 1479 89723844
Haemorrhoids 14.97 10.97 182 902942 26520 89698803
Graft versus host disease in gastrointestinal tract 14.96 10.97 13 903111 4375 89720948
Nasal discomfort 14.95 10.97 20 903104 5528 89719795
Infusion site infection 14.94 10.97 4 903120 2656 89722667
Tonsillolith 14.94 10.97 7 903117 25 89725298
Adhesiolysis 14.94 10.97 7 903117 25 89725298
Koebner phenomenon 14.94 10.97 7 903117 25 89725298
Treatment delayed 14.92 10.97 20 903104 415 89724908
Acute psychosis 14.88 10.97 6 903118 3072 89722251
Eczema 14.81 10.97 407 902717 52463 89672860
Squamous cell carcinoma 14.81 10.97 160 902964 9941 89715382
Incorrect dosage administered 14.80 10.97 5 903119 2855 89722468
Volvulus 14.80 10.97 52 903072 2151 89723172
Alopecia areata 14.79 10.97 49 903075 1966 89723357
Communication disorder 14.79 10.97 7 903117 3259 89722064
Appendicectomy 14.78 10.97 73 903051 3523 89721800
Cardiopulmonary failure 14.78 10.97 12 903112 4176 89721147
Cross sensitivity reaction 14.77 10.97 5 903119 2852 89722471
Spinal fracture 14.76 10.97 144 902980 21872 89703451
Hypertensive crisis 14.76 10.97 110 903014 17674 89707649
Steatohepatitis 14.75 10.97 28 903096 788 89724535
Ulcer haemorrhage 14.74 10.97 355 902769 25966 89699357
Photopsia 14.70 10.97 17 903107 5007 89720316
Drug specific antibody absent 14.69 10.97 11 903113 108 89725215
Noninfective chorioretinitis 14.68 10.97 5 903119 5 89725318
Spleen tuberculosis 14.68 10.97 5 903119 5 89725318
Abortion 14.67 10.97 61 903063 2734 89722589
Infusion site reaction 14.65 10.97 269 902855 18770 89706553
Polyserositis 14.60 10.97 25 903099 648 89724675
Presbyacusis 14.60 10.97 6 903118 3036 89722287
Conjunctival haemorrhage 14.58 10.97 11 903113 3973 89721350
Total lung capacity decreased 14.52 10.97 10 903114 3785 89721538
Hepatitis B reactivation 14.51 10.97 11 903113 3963 89721360
Episiotomy 14.48 10.97 4 903120 0 89725323
CSF white blood cell count positive 14.48 10.97 4 903120 0 89725323
Enterostomy closure 14.48 10.97 4 903120 0 89725323
Antibiotic prophylaxis 14.48 10.97 4 903120 0 89725323
Pelvic pouch procedure 14.48 10.97 4 903120 0 89725323
Appendiceal mucocoele 14.48 10.97 4 903120 0 89725323
Orbital granuloma 14.48 10.97 4 903120 0 89725323
Giant cell tumour of tendon sheath 14.48 10.97 4 903120 0 89725323
Enuresis 14.44 10.97 8 903116 3406 89721917
Incoherent 14.40 10.97 17 903107 4960 89720363
Right ventricular dysfunction 14.38 10.97 3 903121 2361 89722962
Ischaemia 14.36 10.97 19 903105 5276 89720047
Melkersson-Rosenthal syndrome 14.35 10.97 6 903118 15 89725308
Ovarian adenoma 14.32 10.97 16 903108 273 89725050
Foot fracture 14.29 10.97 183 902941 26423 89698900
Malignant melanoma stage I 14.27 10.97 8 903116 45 89725278
Dyspnoea at rest 14.25 10.97 16 903108 4775 89720548
Viral cardiomyopathy 14.21 10.97 5 903119 6 89725317
Peritoneal cyst 14.21 10.97 5 903119 6 89725317
Cyst 14.17 10.97 238 902886 16323 89709000
Ovarian cyst 14.14 10.97 247 902877 17071 89708252
Libido decreased 14.12 10.97 6 903118 2976 89722347
Hysterectomy 14.09 10.97 177 902947 11407 89713916
Contraindication to medical treatment 14.09 10.97 30 903094 919 89724404
Torticollis 14.08 10.97 4 903120 2554 89722769
Synovial disorder 14.05 10.97 65 903059 3053 89722270
Suture rupture 14.04 10.97 14 903110 208 89725115
Delirium 14.02 10.97 874 902250 103485 89621838
Hepatitis toxic 14.01 10.97 10 903114 3715 89721608
Vulvovaginal swelling 14.01 10.97 27 903097 769 89724554
Tenosynovitis stenosans 14.00 10.97 77 903047 3876 89721447
Liver transplant 13.97 10.97 3 903121 2314 89723009
Anorectal swelling 13.94 10.97 13 903111 177 89725146
Haemoperitoneum 13.89 10.97 9 903115 3519 89721804
Gastrointestinal bacterial overgrowth 13.89 10.97 27 903097 774 89724549
Colectomy total 13.88 10.97 13 903111 178 89725145
Insurance issue 13.88 10.97 59 903065 10899 89714424
Stoma site abscess 13.84 10.97 15 903109 247 89725076
Hypertension 13.82 10.97 4918 898206 452614 89272709
Eye naevus 13.82 10.97 6 903118 17 89725306
Emotional disorder 13.81 10.97 90 903034 14907 89710416
Catheter placement 13.80 10.97 4 903120 2520 89722803
Meningitis leptospiral 13.79 10.97 5 903119 7 89725316
Pulmonary sarcoidosis 13.77 10.97 36 903088 1263 89724060
Alanine aminotransferase abnormal 13.76 10.97 97 903027 5329 89719994
Palmoplantar keratoderma 13.74 10.97 9 903115 3498 89721825
Hydrocholecystis 13.73 10.97 8 903116 49 89725274
Polycystic ovaries 13.65 10.97 22 903102 5632 89719691
Steroid diabetes 13.61 10.97 4 903120 2498 89722825
Rash pruritic 13.61 10.97 973 902151 81241 89644082
Lower respiratory tract inflammation 13.60 10.97 11 903113 122 89725201
Neoplasm of appendix 13.60 10.97 8 903116 50 89725273
Electrocardiogram ST segment elevation 13.57 10.97 12 903112 4004 89721319
Craniocerebral injury 13.56 10.97 8 903116 3290 89722033
Breast cancer female 13.51 10.97 216 902908 14670 89710653
Neonatal respiratory distress syndrome 13.51 10.97 7 903117 3094 89722229
Ear pain 13.51 10.97 455 902669 57247 89668076
Intercepted product prescribing error 13.49 10.97 16 903108 292 89725031
Oesophageal candidiasis 13.48 10.97 30 903094 6799 89718524
Platelet count abnormal 13.43 10.97 14 903110 4321 89721002
Spinal fusion surgery 13.41 10.97 184 902940 12099 89713224
Hypothalamo-pituitary disorder 13.41 10.97 3 903121 2249 89723074
Swelling of eyelid 13.38 10.97 21 903103 5433 89719890
Sensation of foreign body 13.38 10.97 27 903097 6339 89718984
Vasodilatation 13.34 10.97 6 903118 2878 89722445
Aortic elongation 13.34 10.97 6 903118 19 89725304
Hyperaesthesia 13.32 10.97 58 903066 10644 89714679
Central nervous system inflammation 13.32 10.97 13 903111 188 89725135
Periorbital oedema 13.31 10.97 30 903094 6769 89718554
Adverse food reaction 13.31 10.97 9 903115 74 89725249
Blepharitis 13.29 10.97 12 903112 3964 89721359
Effusion 13.27 10.97 48 903076 2014 89723309
Post procedural discharge 13.27 10.97 21 903103 509 89724814
Neutropenic colitis 13.26 10.97 13 903111 4130 89721193
Psychomotor skills impaired 13.25 10.97 6 903118 2866 89722457
Nasal dryness 13.23 10.97 22 903102 5561 89719762
Blood parathyroid hormone increased 13.22 10.97 9 903115 3428 89721895
Blood disorder 13.21 10.97 37 903087 7753 89717570
Granulocyte count decreased 13.20 10.97 4 903120 2448 89722875
Dyspepsia 13.19 10.97 2207 900917 195953 89529370
Sebaceous gland infection 13.19 10.97 12 903112 158 89725165
Odynophagia 13.18 10.97 46 903078 8997 89716326
Conjunctivitis 13.15 10.97 187 902937 26519 89698804
Subdural haemorrhage 13.12 10.97 9 903115 3414 89721909
Skin swelling 13.10 10.97 29 903095 6585 89718738
Vaginal operation 13.04 10.97 5 903119 9 89725314
Vasculitis necrotising 13.03 10.97 24 903100 660 89724663
Blood magnesium increased 13.01 10.97 9 903115 3399 89721924
Colon operation 12.99 10.97 20 903104 473 89724850
Sinus pain 12.99 10.97 21 903103 5368 89719955
Anogenital dysplasia 12.98 10.97 7 903117 36 89725287
Mesenteric vascular insufficiency 12.98 10.97 7 903117 36 89725287
Rotator cuff syndrome 12.98 10.97 227 902897 15692 89709631
Infectious mononucleosis 12.97 10.97 47 903077 1974 89723349
Red cell distribution width increased 12.96 10.97 70 903054 12137 89713186
Left ventricular hypertrophy 12.96 10.97 26 903098 6118 89719205
Wound infection pseudomonas 12.94 10.97 47 903077 1976 89723347
Screaming 12.92 10.97 11 903113 3739 89721584
Urinary tract infection bacterial 12.91 10.97 27 903097 6258 89719065
Metastases to spine 12.87 10.97 11 903113 3732 89721591
Subcutaneous drug absorption impaired 12.85 10.97 198 902926 13347 89711976
Mesangioproliferative glomerulonephritis 12.83 10.97 9 903115 79 89725244
Oral neoplasm 12.83 10.97 9 903115 79 89725244
Bursitis infective staphylococcal 12.83 10.97 7 903117 37 89725286
Anaemia macrocytic 12.82 10.97 16 903108 4556 89720767
Stomal hernia 12.76 10.97 16 903108 310 89725013
Application site pain 12.74 10.97 17 903107 4703 89720620
Perineal fistula 12.73 10.97 10 903114 106 89725217
Ear lobe infection 12.70 10.97 5 903119 10 89725313
Incision site inflammation 12.69 10.97 6 903118 22 89725301
Incision site pruritus 12.69 10.97 6 903118 22 89725301
COVID-19 12.67 10.97 1893 901231 166950 89558373
Proctitis ulcerative 12.64 10.97 16 903108 313 89725010
Acute pulmonary histoplasmosis 12.64 10.97 11 903113 136 89725187
Plasmacytoma 12.63 10.97 6 903118 2787 89722536
Guillain-Barre syndrome 12.62 10.97 84 903040 4528 89720795
Mean cell haemoglobin concentration abnormal 12.58 10.97 11 903113 137 89725186
Macular degeneration 12.57 10.97 480 902644 37490 89687833
Chondropathy 12.55 10.97 54 903070 2458 89722865
Reactive gastropathy 12.52 10.97 23 903101 631 89724692
Seroconversion test positive 12.49 10.97 6 903118 23 89725300
Signet-ring cell carcinoma 12.49 10.97 6 903118 23 89725300
HLA-B*27 positive 12.48 10.97 14 903110 240 89725083
Dermatitis acneiform 12.47 10.97 28 903096 6326 89718997
White blood cell count abnormal 12.46 10.97 36 903088 7468 89717855
Laryngospasm 12.46 10.97 9 903115 3324 89721999
Dysgraphia 12.45 10.97 11 903113 3672 89721651
Periodontitis 12.44 10.97 12 903112 3841 89721482
Tooth fracture 12.44 10.97 74 903050 12526 89712797
Granulomatous dermatitis 12.43 10.97 13 903111 205 89725118
Stoma site ulcer 12.43 10.97 15 903109 279 89725044
Sputum increased 12.41 10.97 7 903117 2950 89722373
Hypoproteinaemia 12.40 10.97 8 903116 3134 89722189
Transplant dysfunction 12.34 10.97 21 903103 5261 89720062
Wrist fracture 12.33 10.97 98 903026 15526 89709797
Benign lung neoplasm 12.30 10.97 9 903115 85 89725238
Renal cyst 12.29 10.97 77 903047 12873 89712450
Rash vesicular 12.27 10.97 252 902872 17945 89707378
Staphylococcal pharyngitis 12.27 10.97 4 903120 3 89725320
Ulnar neuritis 12.27 10.97 4 903120 3 89725320
Inner ear inflammation 12.27 10.97 4 903120 3 89725320
Activated partial thromboplastin time ratio increased 12.27 10.97 4 903120 3 89725320
Systemic candida 12.26 10.97 19 903105 4940 89720383
Pulmonary pain 12.26 10.97 20 903104 5094 89720229
Pupillary reflex impaired 12.24 10.97 5 903119 2540 89722783
Foreign body sensation in eyes 12.22 10.97 9 903115 3291 89722032
Benign neoplasm of skin 12.21 10.97 12 903112 175 89725148
Allergic sinusitis 12.21 10.97 3 903121 2110 89723213
Suture related complication 12.19 10.97 16 903108 325 89724998
Joint instability 12.10 10.97 37 903087 1422 89723901
Procedural complication 12.06 10.97 100 903024 5778 89719545
Breast pain 12.05 10.97 58 903066 10360 89714963
Tumour haemorrhage 12.05 10.97 3 903121 2091 89723232
Oxygen saturation abnormal 12.03 10.97 15 903109 4273 89721050
Inability to afford medication 12.02 10.97 11 903113 3611 89721712
Uterine polyp 12.01 10.97 54 903070 2506 89722817
Creatinine urine abnormal 12.00 10.97 7 903117 43 89725280
Heart rate abnormal 11.98 10.97 26 903098 5945 89719378
Deafness neurosensory 11.97 10.97 32 903092 6809 89718514
Pulmonary granuloma 11.96 10.97 40 903084 1613 89723710
Bacterial infection 11.95 10.97 163 902961 23281 89702042
Abdominal neoplasm 11.94 10.97 17 903107 374 89724949
Callus formation delayed 11.93 10.97 6 903118 26 89725297
Coronavirus infection 11.92 10.97 23 903101 5492 89719831
Diabetic retinopathy 11.92 10.97 6 903118 2696 89722627
Thyroid cancer 11.89 10.97 105 903019 6179 89719144
Sternal fracture 11.88 10.97 7 903117 2880 89722443
Fracture delayed union 11.86 10.97 53 903071 2453 89722870
Pleural thickening 11.85 10.97 9 903115 3239 89722084
Hepatic pain 11.84 10.97 11 903113 3584 89721739
Lipoma 11.84 10.97 60 903064 2926 89722397
Malignant melanoma stage III 11.82 10.97 5 903119 13 89725310
Postpartum disorder 11.82 10.97 5 903119 13 89725310
Drain placement 11.80 10.97 9 903115 91 89725232
Crying 11.78 10.97 182 902942 25463 89699860
Social avoidant behaviour 11.77 10.97 10 903114 3403 89721920
Eosinophil morphology abnormal 11.74 10.97 4 903120 4 89725319
Drain removal 11.74 10.97 4 903120 4 89725319
Pseudomyxoma peritonei 11.74 10.97 4 903120 4 89725319
Tongue dysplasia 11.74 10.97 4 903120 4 89725319
Gardnerella infection 11.74 10.97 4 903120 4 89725319
Perfusion brain scan abnormal 11.74 10.97 4 903120 4 89725319
Linear IgA disease 11.72 10.97 4 903120 2270 89723053
Skin discharge 11.72 10.97 9 903115 92 89725231
Incontinence 11.68 10.97 82 903042 13353 89711970
Haemorrhoidal haemorrhage 11.68 10.97 22 903102 5301 89720022
Splenomegaly 11.68 10.97 78 903046 12846 89712477
Knee operation 11.67 10.97 113 903011 6823 89718500
Spinal instability 11.67 10.97 11 903113 152 89725171
Hepatorenal syndrome 11.66 10.97 3 903121 2045 89723278
Haemorrhage subcutaneous 11.65 10.97 10 903114 3386 89721937
Nephrogenic anaemia 11.61 10.97 5 903119 2461 89722862
Device difficult to use 11.60 10.97 115 903009 17410 89707913
Labelled drug-drug interaction issue 11.59 10.97 4 903120 2254 89723069
T-cell lymphoma 11.59 10.97 25 903099 773 89724550
Bradyarrhythmia 11.57 10.97 5 903119 2456 89722867
Bundle branch block left 11.57 10.97 40 903084 7845 89717478
Product taste abnormal 11.57 10.97 5 903119 2455 89722868
Cardiolipin antibody 11.56 10.97 5 903119 14 89725309
Injection 11.56 10.97 5 903119 14 89725309
Eczema infected 11.55 10.97 11 903113 154 89725169
Cutaneous tuberculosis 11.54 10.97 12 903112 188 89725135
Self-injurious ideation 11.53 10.97 9 903115 3194 89722129
Device failure 11.52 10.97 33 903091 6864 89718459
Oropharyngeal discomfort 11.51 10.97 39 903085 7696 89717627
Duodenitis 11.48 10.97 16 903108 4347 89720976
Enzyme level increased 11.47 10.97 19 903105 479 89724844
Urinary tract infection enterococcal 11.47 10.97 8 903116 3008 89722315
Stillbirth 11.44 10.97 37 903087 7406 89717917
Sarcoid-like reaction 11.44 10.97 12 903112 190 89725133
Impetigo 11.43 10.97 38 903086 1528 89723795
SARS-CoV-2 antibody test positive 11.42 10.97 6 903118 29 89725294
Musculoskeletal discomfort 11.42 10.97 144 902980 20847 89704476
Product use complaint 11.41 10.97 11 903113 3522 89721801
Nasal crusting 11.35 10.97 18 903106 437 89724886
Acinetobacter infection 11.32 10.97 3 903121 2005 89723318
Tooth loss 11.30 10.97 38 903086 7516 89717807
Lip and/or oral cavity cancer 11.29 10.97 27 903097 895 89724428
Oedema genital 11.29 10.97 12 903112 193 89725130
Papillary renal cell carcinoma 11.28 10.97 4 903120 5 89725318
Laboratory test abnormal 11.26 10.97 324 902800 41530 89683793
Pelvic venous thrombosis 11.26 10.97 3 903121 1998 89723325
Volvulus of small bowel 11.25 10.97 8 903116 72 89725251
Venous thrombosis 11.20 10.97 24 903100 5513 89719810
Vogt-Koyanagi-Harada disease 11.20 10.97 17 903107 397 89724926
Angioimmunoblastic T-cell lymphoma 11.18 10.97 13 903111 232 89725091
Synovial rupture 11.16 10.97 15 903109 312 89725011
Breast abscess 11.16 10.97 46 903078 2054 89723269
Lymphatic fistula 11.15 10.97 36 903088 1425 89723898
Dolichocolon 11.15 10.97 7 903117 50 89725273
Anal ulcer 11.15 10.97 25 903099 794 89724529
Eyelid disorder 11.14 10.97 4 903120 2199 89723124
Extrapulmonary tuberculosis 11.14 10.97 17 903107 399 89724924
Haemoglobin abnormal 11.12 10.97 35 903089 7065 89718258
Urticarial vasculitis 11.12 10.97 29 903095 1016 89724307
Urine analysis abnormal 11.09 10.97 22 903102 5199 89720124
Blood calcium abnormal 11.06 10.97 3 903121 1974 89723349
Urosepsis 11.05 10.97 147 902977 21085 89704238
Seborrhoeic dermatitis 11.04 10.97 40 903084 1680 89723643
Ganglioneuroma 11.03 10.97 10 903114 131 89725192
Lip squamous cell carcinoma 11.00 10.97 11 903113 164 89725159
Rectal cancer metastatic 10.98 10.97 14 903110 276 89725047
Thyroiditis 10.98 10.97 12 903112 3625 89721698

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug ineffective 3946.16 11.67 9455 211574 620742 41779564
Therapy interrupted 1693.10 11.67 1185 219844 21065 42379241
Therapeutic product effect decreased 1404.12 11.67 1345 219684 37805 42362501
Joint swelling 1284.79 11.67 1671 219358 66351 42333955
Arthralgia 1129.83 11.67 2950 218079 202288 42198018
Psoriasis 1065.84 11.67 1287 219742 47317 42352989
Drug interaction 1046.97 11.67 92 220937 266907 42133399
Acute kidney injury 898.44 11.67 392 220637 366945 42033361
Toxicity to various agents 828.75 11.67 106 220923 229030 42171276
Febrile neutropenia 776 11.67 47 220982 185656 42214650
Intestinal stenosis 727.58 11.67 334 220695 2470 42397836
Synovitis 719.22 11.67 617 220412 14950 42385356
Hypotension 622.60 11.67 279 220750 257352 42142954
Injection site pain 586.31 11.67 1065 219964 56733 42343573
Pain 576.03 11.67 2653 218376 242195 42158111
Treatment failure 573 11.67 1104 219925 61520 42338786
Musculoskeletal stiffness 549.02 11.67 1035 219994 56730 42343576
Drug intolerance 527.54 11.67 1238 219791 79186 42321120
Malignant neoplasm progression 520.83 11.67 8 221021 108392 42291914
Neutropenia 500.64 11.67 204 220825 199227 42201079
Drug abuse 478.74 11.67 14 221015 104757 42295549
Arthritis 470.25 11.67 809 220220 41256 42359050
Ileal stenosis 468.79 11.67 218 220811 1666 42398640
Arthropathy 465.56 11.67 666 220363 28931 42371375
Therapeutic product effect incomplete 457.56 11.67 1085 219944 69854 42330452
Disease progression 455.29 11.67 95 220934 143561 42256745
C-reactive protein abnormal 454.28 11.67 380 220649 8881 42391425
Frequent bowel movements 446.41 11.67 553 220476 20854 42379452
Contraindicated product administered 439.77 11.67 597 220432 24675 42375631
Thrombocytopenia 418.74 11.67 233 220796 190046 42210260
Drug specific antibody present 415.39 11.67 259 220770 3747 42396559
Intestinal obstruction 415.27 11.67 603 220426 26555 42373751
Anaemia 396.85 11.67 524 220505 279754 42120552
Apparent death 395.28 11.67 244 220785 3464 42396842
Psoriatic arthropathy 378.31 11.67 552 220477 24415 42375891
Anal fistula 355.62 11.67 279 220750 5934 42394372
Rheumatoid arthritis 346.91 11.67 714 220315 41726 42358580
Fistula 344.01 11.67 303 220726 7609 42392697
Gastrointestinal inflammation 333.80 11.67 238 220791 4354 42395952
Ankylosing spondylitis 330.60 11.67 282 220747 6774 42393532
Hyponatraemia 329.94 11.67 63 220966 101399 42298907
Platelet count decreased 310.10 11.67 166 220863 138415 42261891
Large intestinal stenosis 307.64 11.67 166 220863 1797 42398509
Inflammation 302.41 11.67 591 220438 33256 42367050
Mobility decreased 289.73 11.67 595 220434 34711 42365595
Red blood cell sedimentation rate increased 289.33 11.67 305 220724 9619 42390687
Overdose 285.24 11.67 95 220934 105169 42295137
Bradycardia 278.08 11.67 53 220976 85431 42314875
Osteoarthritis 273.47 11.67 470 220559 23935 42376371
Tuberculosis 270.91 11.67 297 220732 9802 42390504
Abdominal adhesions 269.34 11.67 146 220883 1596 42398710
Uveitis 267.18 11.67 283 220746 8975 42391331
Abscess 266.89 11.67 349 220680 13899 42386407
C-reactive protein increased 266.69 11.67 830 220199 62730 42337576
Injection site haemorrhage 265.51 11.67 316 220713 11420 42388886
Dyspnoea 265.48 11.67 1288 219741 441333 41958973
Pain in extremity 263.10 11.67 1503 219526 149101 42251205
Knee arthroplasty 258.01 11.67 271 220758 8510 42391796
Surgery 257.50 11.67 383 220646 17233 42383073
Hyperkalaemia 255.19 11.67 53 220976 80405 42319901
Infection 249.90 11.67 1197 219832 110871 42289435
Small intestinal stenosis 248.98 11.67 112 220917 785 42399521
Impaired work ability 248.27 11.67 310 220719 11781 42388525
Small intestinal obstruction 248.04 11.67 370 220659 16691 42383615
Completed suicide 247.81 11.67 95 220934 96370 42303936
Therapy cessation 243.94 11.67 405 220624 20045 42380261
Bone erosion 239.72 11.67 192 220837 4211 42396095
Demyelination 238.48 11.67 175 220854 3354 42396952
Neutrophil count decreased 237.09 11.67 26 221003 63389 42336917
Somnolence 236.13 11.67 230 220799 140875 42259431
Lymphoma 235.10 11.67 329 220700 13992 42386314
Confusional state 234.12 11.67 316 220713 167281 42233025
Disability 233.84 11.67 215 220814 5718 42394588
Lupus-like syndrome 228.17 11.67 163 220866 2991 42397315
Red blood cell sedimentation rate abnormal 227.65 11.67 176 220853 3660 42396646
Abscess intestinal 224.00 11.67 131 220898 1675 42398631
Disseminated tuberculosis 211.34 11.67 149 220880 2675 42397631
Constipation 210.86 11.67 322 220707 161969 42238337
Cytokine release syndrome 210.81 11.67 4 221025 44523 42355783
Sarcoidosis 209.97 11.67 165 220864 3517 42396789
Loss of personal independence in daily activities 209.37 11.67 651 220378 49165 42351141
Intentional overdose 208.81 11.67 15 221014 51441 42348865
Diverticulitis 207.48 11.67 401 220628 22372 42377934
Injection site erythema 206.95 11.67 374 220655 19821 42380485
Hypoxia 205.39 11.67 54 220975 69732 42330574
Inflammatory bowel disease 203.10 11.67 159 220870 3370 42396936
Tuberculin test positive 202.62 11.67 106 220923 1072 42399234
Pancytopenia 200.36 11.67 189 220840 117554 42282752
Death 200.07 11.67 1528 219501 469657 41930649
Electrocardiogram QT prolonged 197.40 11.67 13 221016 47932 42352374
Hallucination 197.21 11.67 31 220998 57476 42342830
Intestinal fistula 193.77 11.67 103 220926 1079 42399227
Herpes zoster 188.98 11.67 535 220494 38342 42361964
Hypokalaemia 188.60 11.67 68 220961 71653 42328653
Colectomy 186.27 11.67 128 220901 2201 42398105
Blood creatinine increased 183.18 11.67 180 220849 109823 42290483
Rhabdomyolysis 182.58 11.67 88 220941 77931 42322375
Hypoglycaemia 182.56 11.67 43 220986 59811 42340495
Intestinal fibrosis 179.29 11.67 55 220974 97 42400209
Hidradenitis 179.08 11.67 112 220917 1629 42398677
Drug hypersensitivity 178.73 11.67 1000 220029 98389 42301917
Drug reaction with eosinophilia and systemic symptoms 177.47 11.67 10 221019 42065 42358241
Faecal calprotectin increased 177.19 11.67 139 220890 2955 42397351
Injection site reaction 175.10 11.67 302 220727 15419 42384887
Enthesopathy 174.99 11.67 167 220862 4661 42395645
Off label use 174.05 11.67 2303 218726 636032 41764274
Cardiac arrest 172.84 11.67 187 220842 109133 42291173
Respiratory failure 172.45 11.67 248 220781 127884 42272422
Haematochezia 170.53 11.67 677 220352 57759 42342547
Injection site papule 170.31 11.67 66 220963 299 42400007
Pyoderma gangrenosum 168.98 11.67 113 220916 1854 42398452
Chondropathy 168.71 11.67 95 220934 1125 42399181
Myelosuppression 166.48 11.67 11 221018 40450 42359856
Lactic acidosis 165.57 11.67 20 221009 45241 42355065
Systemic lupus erythematosus 164.78 11.67 222 220807 9102 42391204
Metabolic acidosis 164.74 11.67 34 220995 51824 42348482
International normalised ratio increased 160.63 11.67 28 221001 48140 42352166
Intestinal resection 159.93 11.67 107 220922 1757 42398549
Delirium 157.68 11.67 39 220990 52480 42347826
Mycobacterium tuberculosis complex test positive 155.95 11.67 98 220931 1438 42398868
Abdominal abscess 154.67 11.67 160 220869 4933 42395373
Product use in unapproved indication 153.11 11.67 470 220559 183986 42216320
Anal abscess 152.81 11.67 196 220833 7654 42392652
Vomiting 152.60 11.67 880 220149 288843 42111463
Tachycardia 151.01 11.67 181 220848 100906 42299400
Agitation 149.77 11.67 73 220956 64241 42336065
Depressed level of consciousness 149.21 11.67 33 220996 47937 42352369
Coma 149.14 11.67 46 220983 53508 42346798
Cardio-respiratory arrest 148.47 11.67 59 220970 58577 42341729
Sacroiliitis 146.99 11.67 104 220925 1878 42398428
Leukopenia 145.67 11.67 105 220924 74641 42325665
Nasopharyngitis 145.62 11.67 837 220192 83159 42317147
Hypersensitivity 143.49 11.67 748 220281 71622 42328684
Pustular psoriasis 142.56 11.67 105 220924 2024 42398282
Lymphadenopathy 141.99 11.67 438 220591 32927 42367379
Plasma cell myeloma 137.75 11.67 38 220991 47540 42352766
Device issue 136.90 11.67 249 220780 13260 42387046
Polyarthritis 136.70 11.67 150 220879 4954 42395352
Septic shock 136.01 11.67 165 220864 91507 42308799
Decreased appetite 135.41 11.67 529 220500 192608 42207698
Malignant melanoma 133.97 11.67 202 220827 9198 42391108
Joint stiffness 133.70 11.67 234 220795 12088 42388218
Ileostomy 133.16 11.67 79 220950 1039 42399267
Mental status changes 132.97 11.67 28 221001 42087 42358219
Colitis ulcerative 132.89 11.67 366 220663 25809 42374497
Sedation 132.47 11.67 6 221023 30469 42369837
IgA nephropathy 132.39 11.67 105 220924 2269 42398037
Multiple organ dysfunction syndrome 132.32 11.67 186 220843 96849 42303457
Incorrect dose administered 132.12 11.67 585 220444 52389 42347917
Intervertebral disc protrusion 131.66 11.67 219 220810 10853 42389453
Gastrointestinal disorder 128.54 11.67 531 220498 46122 42354184
White blood cell count decreased 128.51 11.67 235 220794 110161 42290145
Pulmonary tuberculosis 127.53 11.67 150 220879 5351 42394955
Injection site swelling 127.52 11.67 276 220753 16697 42383609
Hyperglycaemia 124.83 11.67 41 220988 45818 42354488
Urticaria 124.57 11.67 732 220297 73304 42327002
Gastrointestinal haemorrhage 122.92 11.67 198 220831 97528 42302778
Fall 122.49 11.67 714 220315 233806 42166500
Illness 121.06 11.67 343 220686 24587 42375719
Renal impairment 121.01 11.67 243 220786 109985 42290321
Intentional product misuse 120.55 11.67 87 220942 61813 42338493
Neck pain 120.35 11.67 386 220643 29628 42370678
Joint range of motion decreased 119.70 11.67 173 220856 7580 42392726
Serotonin syndrome 119.67 11.67 3 221026 25842 42374464
Oxygen saturation decreased 119.48 11.67 96 220933 64591 42335715
Fistula discharge 118.32 11.67 73 220956 1035 42399271
Intestinal anastomosis 117.96 11.67 55 220974 423 42399883
Abdominal pain 117.14 11.67 1505 219524 188966 42211340
Atrial fibrillation 116.98 11.67 354 220675 139239 42261067
Drug eruption 116.49 11.67 322 220707 22753 42377553
Acne cystic 116.46 11.67 58 220971 524 42399782
Gastrointestinal scarring 116.38 11.67 42 220987 149 42400157
Sleep disorder due to general medical condition, insomnia type 115.75 11.67 80 220949 1389 42398917
Dehydration 114.91 11.67 365 220664 141402 42258904
Wheezing 114.74 11.67 71 220958 54710 42345596
Dizziness 114.69 11.67 789 220240 248465 42151841
Encephalopathy 114.19 11.67 36 220993 41297 42359009
Agranulocytosis 113.27 11.67 13 221016 30599 42369707
Gastrointestinal fistula 112.87 11.67 57 220972 532 42399774
Intentional dose omission 112.60 11.67 182 220847 8804 42391502
Henoch-Schonlein purpura 111.21 11.67 91 220938 2059 42398247
Spinal instability 110.72 11.67 57 220972 556 42399750
Cardiogenic shock 109.87 11.67 25 221004 35615 42364691
Ileocaecal resection 109.55 11.67 50 220979 364 42399942
Gastrointestinal stenosis 108.57 11.67 39 220990 136 42400170
Neuropathy peripheral 108.01 11.67 229 220800 101624 42298682
Therapy non-responder 107.47 11.67 554 220475 52805 42347501
Bone cyst 107.35 11.67 80 220949 1571 42398735
Mucosal inflammation 106.20 11.67 62 220967 49312 42350994
Hepatosplenic T-cell lymphoma 105.93 11.67 52 220977 454 42399852
Neoplasm progression 105.61 11.67 13 221016 28987 42371319
Neurotoxicity 104.99 11.67 4 221025 23647 42376659
Enteritis 104.11 11.67 195 220834 10621 42389685
Gastrointestinal wall thickening 103.98 11.67 82 220947 1757 42398549
Colitis 103.33 11.67 497 220532 46075 42354231
Pneumonia legionella 102.89 11.67 89 220940 2179 42398127
Mass 102.76 11.67 172 220857 8567 42391739
Tenosynovitis 102.22 11.67 124 220905 4571 42395735
Hypocalcaemia 101.78 11.67 17 221012 30156 42370150
Defaecation urgency 101.44 11.67 110 220919 3584 42396722
Orthostatic hypotension 101.42 11.67 18 221011 30552 42369754
Tumour lysis syndrome 101.37 11.67 3 221026 22228 42378078
Synovial cyst 101.14 11.67 94 220935 2535 42397771
Drug delivery system malfunction 100.47 11.67 50 220979 451 42399855
Alanine aminotransferase abnormal 100.28 11.67 126 220903 4818 42395488
Rheumatoid factor positive 100.03 11.67 59 220970 767 42399539
Pneumonia aspiration 99.33 11.67 69 220960 50009 42350297
Immunosuppression 98.90 11.67 166 220863 8287 42392019
Gastrointestinal obstruction 98.11 11.67 66 220963 1094 42399212
Fear of injection 97.82 11.67 82 220947 1921 42398385
Blood pressure decreased 97.57 11.67 95 220934 58237 42342069
Faecal calprotectin abnormal 97.47 11.67 43 220986 286 42400020
Atlantoaxial instability 97.37 11.67 47 220982 394 42399912
Iridocyclitis 96.76 11.67 85 220944 2126 42398180
Seizure 95.18 11.67 314 220715 120247 42280059
Arthritis bacterial 95.10 11.67 134 220895 5734 42394572
Intervertebral disc space narrowing 94.11 11.67 64 220965 1081 42399225
Injection site warmth 93.82 11.67 91 220938 2592 42397714
Syncope 93.74 11.67 238 220791 99168 42301138
No adverse event 92.82 11.67 43 220986 38978 42361328
Stenosis 92.40 11.67 81 220948 2020 42398286
Device malfunction 92.09 11.67 200 220829 12127 42388179
Respiratory arrest 91.59 11.67 18 221011 28406 42371900
Dislocation of vertebra 91.37 11.67 45 220984 396 42399910
Drug level decreased 91.25 11.67 176 220853 9801 42390505
Joint ankylosis 91.02 11.67 73 220956 1604 42398702
Anti-cyclic citrullinated peptide antibody positive 90.75 11.67 77 220952 1835 42398471
Hypomagnesaemia 89.80 11.67 19 221010 28469 42371837
Impaired healing 89.10 11.67 241 220788 16812 42383494
Pulmonary thrombosis 88.58 11.67 157 220872 8191 42392115
Skin plaque 87.86 11.67 129 220900 5734 42394572
Unresponsive to stimuli 87.38 11.67 27 221002 31376 42368930
Gastrointestinal mucosa hyperaemia 86.88 11.67 41 220988 325 42399981
Blood bilirubin increased 86.78 11.67 56 220973 42196 42358110
Small intestinal resection 86.19 11.67 50 220979 629 42399677
Aggression 86.07 11.67 62 220967 44101 42356205
Hip arthroplasty 85.76 11.67 121 220908 5184 42395122
Suicide attempt 85.64 11.67 68 220961 46032 42354274
Immunodeficiency 83.75 11.67 142 220887 7148 42393158
Joint lock 83.17 11.67 64 220965 1321 42398985
Diarrhoea haemorrhagic 83.14 11.67 146 220883 7561 42392745
Mineral metabolism disorder 82.36 11.67 41 220988 370 42399936
Dermatitis psoriasiform 81.88 11.67 76 220953 2046 42398260
Enterocutaneous fistula 81.76 11.67 61 220968 1200 42399106
Restlessness 81.65 11.67 25 221004 29224 42371082
Joint arthroplasty 81.23 11.67 55 220974 922 42399384
Obstructive airways disorder 81.22 11.67 15 221014 24744 42375562
Respiratory distress 81.13 11.67 59 220970 41761 42358545
Full blood count abnormal 80.80 11.67 27 221002 29849 42370457
Rash maculo-papular 80.79 11.67 47 220982 37456 42362850
Cholestasis 80.13 11.67 35 220994 32844 42367462
B-cell lymphoma 79.33 11.67 112 220917 4801 42395505
Intestinal anastomosis complication 78.93 11.67 32 220997 167 42400139
Urinary retention 78.76 11.67 62 220967 42152 42358154
Drug specific antibody 78.69 11.67 40 220989 379 42399927
Musculoskeletal pain 78.48 11.67 362 220667 32978 42367328
Dysphagia 78.34 11.67 162 220867 72557 42327749
Subileus 78.30 11.67 94 220935 3427 42396879
Pouchitis 77.89 11.67 53 220976 896 42399410
Injection site pruritus 77.70 11.67 159 220870 9246 42391060
Infusion related reaction 76.62 11.67 123 220906 60683 42339623
Intestinal ulcer 76.39 11.67 55 220974 1022 42399284
Toxic epidermal necrolysis 76.24 11.67 22 221007 26728 42373578
Intestinal perforation 76.23 11.67 172 220857 10702 42389604
Drug level increased 75.69 11.67 21 221008 26179 42374127
Adverse drug reaction 74.90 11.67 388 220641 37046 42363260
Injection site rash 74.74 11.67 118 220911 5594 42394712
Antinuclear antibody increased 74.32 11.67 37 220992 334 42399972
Axial spondyloarthritis 74.18 11.67 42 220987 503 42399803
Pseudopolyp 74.11 11.67 35 220994 278 42400028
Anal stenosis 73.86 11.67 36 220993 309 42399997
Stevens-Johnson syndrome 73.70 11.67 13 221016 22165 42378141
Skin lesion 73.03 11.67 307 220722 26867 42373439
Granuloma 72.60 11.67 97 220932 3944 42396362
Intestinal dilatation 72.33 11.67 62 220967 1499 42398807
Multiple sclerosis 71.90 11.67 136 220893 7462 42392844
Basal cell carcinoma 71.68 11.67 270 220759 22463 42377843
Blood creatine phosphokinase increased 70.62 11.67 88 220941 48250 42352056
Fistula of small intestine 70.59 11.67 43 220986 595 42399711
Hallucination, visual 70.55 11.67 12 221017 21008 42379298
Furuncle 70.44 11.67 92 220937 3658 42396648
Cardiac failure congestive 70.30 11.67 219 220810 85383 42314923
Gastric disorder 69.98 11.67 176 220853 11746 42388560
Respiratory depression 69.83 11.67 8 221021 18860 42381446
Blood glucose increased 69.81 11.67 176 220853 73523 42326783
Hypoaesthesia 69.79 11.67 620 220409 70843 42329463
Drug tolerance decreased 69.62 11.67 73 220956 2287 42398019
Bladder transitional cell carcinoma 68.83 11.67 77 220952 2599 42397707
Gastrointestinal stoma complication 68.55 11.67 60 220969 1493 42398813
Rheumatoid nodule 68.32 11.67 81 220948 2914 42397392
Procedural pain 68.29 11.67 114 220915 5665 42394641
Hepatic cytolysis 67.95 11.67 27 221002 26817 42373489
Gastrointestinal infection 67.95 11.67 124 220905 6619 42393687
Hypervolaemia 67.81 11.67 18 221011 23107 42377199
Alopecia 67.52 11.67 316 220713 28960 42371346
Terminal ileitis 67.21 11.67 41 220988 569 42399737
Latent tuberculosis 66.90 11.67 61 220968 1604 42398702
Foot deformity 66.73 11.67 105 220924 4963 42395343
Upper gastrointestinal haemorrhage 66.65 11.67 37 220992 30262 42370044
Product substitution issue 66.61 11.67 167 220862 11123 42389183
Hypothyroidism 66.60 11.67 42 220987 32042 42368264
Ileectomy 66.12 11.67 27 221002 144 42400162
Terminal state 65.82 11.67 97 220932 4326 42395980
Sleep disorder due to a general medical condition 65.61 11.67 7 221022 17446 42382860
Angioedema 65.61 11.67 74 220955 42403 42357903
Diarrhoea 65.56 11.67 1855 219174 458994 41941312
Tooth fracture 65.52 11.67 94 220935 4090 42396216
Hepatic cirrhosis 65.47 11.67 238 220791 19464 42380842
Altered state of consciousness 65.43 11.67 35 220994 29224 42371082
Crohn's disease 65.27 11.67 79 220950 2905 42397401
Food intolerance 65.23 11.67 60 220969 1596 42398710
Mucous stools 65.18 11.67 73 220956 2467 42397839
Rectal stenosis 64.98 11.67 29 221000 199 42400107
Meniscus injury 64.91 11.67 72 220957 2407 42397899
Labelled drug-drug interaction medication error 64.80 11.67 4 221025 15578 42384728
Drug withdrawal syndrome 64.67 11.67 16 221013 21533 42378773
Antinuclear antibody positive 64.47 11.67 59 220970 1559 42398747
Anastomotic stenosis 64.29 11.67 35 220994 386 42399920
Rectal haemorrhage 64.10 11.67 459 220570 49147 42351159
Joint effusion 63.99 11.67 112 220917 5785 42394521
Impaired quality of life 63.95 11.67 190 220839 13987 42386319
Loss of therapeutic response 63.35 11.67 53 220976 1238 42399068
Sinusitis 63.10 11.67 441 220588 46851 42353455
Peripheral swelling 62.62 11.67 730 220299 89540 42310766
Ventricular tachycardia 61.89 11.67 40 220989 30120 42370186
Intestinal sepsis 61.78 11.67 42 220987 709 42399597
Gastrointestinal oedema 61.52 11.67 60 220969 1721 42398585
Swelling 61.45 11.67 491 220538 54394 42345912
Cardiac failure 61.34 11.67 315 220714 106541 42293765
Inappropriate antidiuretic hormone secretion 61.25 11.67 7 221022 16534 42383772
Onychoclasis 60.95 11.67 72 220957 2580 42397726
Intestinal mucosal hypertrophy 60.82 11.67 25 221004 136 42400170
Steroid dependence 60.76 11.67 118 220911 6604 42393702
Optic neuritis 60.43 11.67 90 220939 4052 42396254
Neoplasm malignant 60.38 11.67 256 220773 22487 42377819
Dry mouth 59.94 11.67 71 220958 39808 42360498
Road traffic accident 59.56 11.67 226 220803 18867 42381439
Lymph node tuberculosis 59.55 11.67 36 220993 491 42399815
Post procedural complication 58.96 11.67 171 220858 12419 42387887
Paradoxical psoriasis 58.32 11.67 24 221005 131 42400175
Multiple sclerosis relapse 58.31 11.67 4 221025 14260 42386046
Lymphocyte count decreased 58.28 11.67 36 220993 27773 42372533
Extrapyramidal disorder 58.21 11.67 8 221021 16404 42383902
Cholangitis sclerosing 58.20 11.67 60 220969 1842 42398464
Bursitis 58.14 11.67 111 220918 6133 42394173
Acne 57.92 11.67 179 220850 13465 42386841
Poisoning 57.62 11.67 5 221024 14694 42385612
Ileal ulcer 57.52 11.67 44 220985 900 42399406
Cutaneous leishmaniasis 57.28 11.67 28 221001 242 42400064
Ileostomy closure 57.21 11.67 20 221009 63 42400243
Inguinal hernia 57.02 11.67 136 220893 8776 42391530
Folliculitis 57.01 11.67 103 220926 5455 42394851
Blood alkaline phosphatase increased 57.01 11.67 54 220975 33543 42366763
Hyperbilirubinaemia 56.94 11.67 18 221011 20617 42379689
Generalised tonic-clonic seizure 56.90 11.67 33 220996 26346 42373960
Proctitis 56.72 11.67 73 220956 2860 42397446
Post procedural inflammation 56.51 11.67 17 221012 27 42400279
Asthenia 56.48 11.67 1071 219958 279722 42120584
Cyst 56.02 11.67 100 220929 5246 42395060
Oedema 55.87 11.67 116 220913 51885 42348421
Intestinal mass 55.86 11.67 37 220992 597 42399709
Histoplasmosis 55.82 11.67 57 220972 1730 42398576
Abnormal behaviour 55.77 11.67 34 220995 26417 42373889
Cutaneous T-cell lymphoma 55.74 11.67 60 220969 1938 42398368
Sinus bradycardia 55.72 11.67 6 221023 14847 42385459
Malaise 55.60 11.67 1467 219562 210689 42189617
Injection site irritation 55.50 11.67 55 220974 1609 42398697
Acute respiratory failure 55.45 11.67 72 220957 38786 42361520
Rectal discharge 55.20 11.67 29 221000 296 42400010
Delusion 55.15 11.67 6 221023 14728 42385578
Melaena 55.08 11.67 72 220957 38674 42361632
Device defective 54.84 11.67 55 220974 1633 42398673
Oedema peripheral 54.73 11.67 447 220582 135629 42264677
Tooth loss 54.60 11.67 86 220943 4068 42396238
Inflammatory marker increased 54.38 11.67 113 220916 6643 42393663
Subdural haematoma 54.25 11.67 26 221003 23112 42377194
Purulent discharge 54.21 11.67 75 220954 3154 42397152
Bone marrow failure 54.06 11.67 55 220974 33038 42367268
Vein rupture 53.95 11.67 43 220986 936 42399370
Testis cancer 53.82 11.67 52 220977 1474 42398832
Histoplasmosis disseminated 53.50 11.67 60 220969 2031 42398275
Alopecia areata 53.18 11.67 29 221000 321 42399985
Enterocolonic fistula 52.99 11.67 20 221009 83 42400223
Ventricular fibrillation 52.79 11.67 47 220982 30076 42370230
Adhesion 52.55 11.67 38 220991 711 42399595
Headache 52.17 11.67 1617 219412 237752 42162554
Hyperphosphataemia 52.15 11.67 4 221025 13000 42387306
Scar 51.66 11.67 110 220919 6578 42393728
Squamous cell carcinoma 51.16 11.67 166 220863 12816 42387490
Pulmonary mass 51.13 11.67 193 220836 16072 42384234
Haematuria 50.97 11.67 143 220886 57656 42342650
Perirectal abscess 50.94 11.67 55 220974 1783 42398523
Osteosclerosis 50.70 11.67 50 220979 1454 42398852
Nephrolithiasis 50.64 11.67 346 220683 36484 42363822
Rectal abscess 50.50 11.67 53 220976 1662 42398644
Shock 50.36 11.67 46 220983 29075 42371231
Aphthous ulcer 50.21 11.67 101 220928 5800 42394506
Postoperative abscess 50.21 11.67 30 220999 400 42399906
Cytology abnormal 49.84 11.67 29 221000 367 42399939
Osteolysis 49.69 11.67 76 220953 3504 42396802
Diabetic ketoacidosis 49.65 11.67 27 221002 22340 42377966
Blood pressure increased 49.60 11.67 317 220712 101611 42298695
Neutropenic sepsis 49.52 11.67 11 221018 15935 42384371
Disseminated intravascular coagulation 49.37 11.67 34 220995 24760 42375546
Medical device implantation 49.36 11.67 34 220995 587 42399719
Rotator cuff syndrome 49.35 11.67 107 220922 6479 42393827
Cognitive disorder 49.09 11.67 63 220966 34109 42366197
Hernia 48.62 11.67 147 220882 10926 42389380
Postoperative wound infection 48.53 11.67 97 220932 5545 42394761
Dystonia 48.41 11.67 5 221024 12785 42387521
Hypophosphataemia 48.40 11.67 24 221005 20921 42379385
Thrombotic microangiopathy 48.39 11.67 9 221020 14773 42385533
Withdrawal syndrome 48.36 11.67 9 221020 14766 42385540
Hepatic steatosis 48.36 11.67 230 220799 21218 42379088
Disorientation 48.34 11.67 71 220958 36318 42363988
Anorectal disorder 48.28 11.67 45 220984 1218 42399088
Erythrodermic psoriasis 48.02 11.67 42 220987 1044 42399262
Dactylitis 47.88 11.67 43 220986 1108 42399198
Skin mass 47.82 11.67 88 220941 4728 42395578
Localised infection 47.78 11.67 221 220808 20152 42380154
Purulence 47.68 11.67 39 220990 882 42399424
Hip surgery 47.66 11.67 46 220983 1302 42399004
Circulatory collapse 47.62 11.67 32 220997 23604 42376702
Blood pressure systolic increased 47.40 11.67 45 220984 27923 42372383
Pulmonary hypertension 47.36 11.67 32 220997 23537 42376769
Activated partial thromboplastin time prolonged 47.35 11.67 12 221017 15891 42384415
Migraine 47.13 11.67 258 220771 25156 42375150
Tachypnoea 46.86 11.67 27 221002 21635 42378671
Full blood count decreased 46.85 11.67 24 221005 20536 42379770
Post procedural infection 46.84 11.67 97 220932 5688 42394618
Clostridium difficile infection 46.81 11.67 237 220792 22422 42377884
Colonic fistula 46.66 11.67 30 220999 459 42399847
Colon dysplasia 46.64 11.67 23 221006 203 42400103
Asthma 46.63 11.67 166 220863 62148 42338158
Rash pustular 46.61 11.67 101 220928 6114 42394192
Myasthenia gravis 46.49 11.67 13 221016 16124 42384182
Unevaluable event 46.48 11.67 321 220708 33967 42366339
Haemoptysis 46.28 11.67 107 220922 46060 42354246
Arthritis reactive 46.18 11.67 27 221002 345 42399961
Psychotic disorder 46.07 11.67 50 220979 29158 42371148
Injection site bruising 45.99 11.67 148 220881 11377 42388929
General physical health deterioration 45.96 11.67 532 220497 150714 42249592
Intestinal polyp 45.96 11.67 45 220984 1297 42399009
Knee operation 45.93 11.67 62 220967 2546 42397760
Pneumonitis 45.71 11.67 92 220937 41626 42358680
Colon cancer 44.86 11.67 131 220898 9550 42390756
Pleural effusion 44.86 11.67 307 220722 96859 42303447
Stoma site abscess 44.72 11.67 16 221013 55 42400251
Flushing 44.69 11.67 77 220952 36951 42363355
Blood phosphorus increased 44.67 11.67 6 221023 12519 42387787
Catarrh 44.57 11.67 97 220932 5889 42394417
Cholecystectomy 44.56 11.67 70 220959 3304 42397002
Anaphylactic shock 44.55 11.67 34 220995 23483 42376823
Cytopenia 43.63 11.67 18 221011 17479 42382827
Coccidioidomycosis 43.57 11.67 36 220993 826 42399480
Gastrointestinal anastomotic stenosis 43.44 11.67 15 221014 45 42400261
Abdominal lymphadenopathy 43.26 11.67 39 220990 1010 42399296
Dyskinesia 42.85 11.67 41 220988 25349 42374957
Oral herpes 42.85 11.67 110 220919 7434 42392872
Hallucination, auditory 42.77 11.67 12 221017 14852 42385454
Night sweats 42.76 11.67 211 220818 19758 42380548
Loss of consciousness 42.53 11.67 292 220737 92062 42308244
Muscle rigidity 42.48 11.67 6 221023 12053 42388253
Rheumatoid factor negative 42.42 11.67 38 220991 976 42399330
Hepatitis B virus test positive 42.39 11.67 25 221004 325 42399981
Vertebral osteophyte 42.27 11.67 15 221014 50 42400256
Accident at work 42.16 11.67 37 220992 924 42399382
Lethargy 42.09 11.67 115 220914 46775 42353531
Iritis 41.98 11.67 49 220980 1733 42398573
Tremor 41.95 11.67 312 220717 96617 42303689
Hepatic failure 41.76 11.67 84 220945 38016 42362290
Dysarthria 41.75 11.67 90 220939 39717 42360589
Injection site urticaria 41.68 11.67 68 220961 3315 42396991
Blood urea increased 41.62 11.67 66 220963 32727 42367579
Injection site extravasation 41.54 11.67 65 220964 3057 42397249
Postoperative adhesion 41.19 11.67 16 221013 73 42400233
Colonoscopy abnormal 41.19 11.67 16 221013 73 42400233
Eosinophilia 41.01 11.67 67 220962 32832 42367474
Photosensitivity reaction 40.99 11.67 152 220877 12550 42387756
Fluid retention 40.73 11.67 63 220966 31556 42368750
Cartilage atrophy 40.70 11.67 12 221017 17 42400289
Wound secretion 40.50 11.67 61 220968 2774 42397532
Herpes simplex oesophagitis 40.46 11.67 22 221007 242 42400064
Procedural intestinal perforation 40.38 11.67 13 221016 29 42400277
Hepatocellular injury 40.24 11.67 38 220991 23640 42376666
Sinus tachycardia 40.23 11.67 29 221000 20624 42379682
Drug level abnormal 40.01 11.67 23 221006 284 42400022
Ascites 39.78 11.67 155 220874 56523 42343783
Post procedural diarrhoea 39.70 11.67 16 221013 82 42400224
Nodule 39.62 11.67 149 220880 12385 42387921
Anastomotic ulcer 39.30 11.67 27 221002 464 42399842
Coronary artery occlusion 39.24 11.67 136 220893 10861 42389445
Subcutaneous abscess 39.13 11.67 78 220951 4450 42395856
Aspiration 39.11 11.67 22 221007 17864 42382442
Pulmonary alveolar haemorrhage 39.01 11.67 14 221015 14802 42385504
Burns second degree 38.97 11.67 93 220936 6003 42394303
Wrist deformity 38.91 11.67 24 221005 340 42399966
Haemodialysis 38.86 11.67 4 221025 10256 42390050
Gamma-glutamyltransferase increased 38.83 11.67 68 220961 32429 42367877
Chronic kidney disease 38.67 11.67 121 220908 47120 42353186
Spinal pain 38.64 11.67 99 220930 6683 42393623
Hodgkin's disease 38.59 11.67 33 220996 795 42399511
Pulmonary oedema 38.48 11.67 144 220885 53128 42347178
Chronic recurrent multifocal osteomyelitis 38.48 11.67 12 221017 23 42400283
Clinically isolated syndrome 38.40 11.67 9 221020 0 42400306
T-cell lymphoma 38.25 11.67 38 220991 1115 42399191
Arthroscopy 38.22 11.67 18 221011 142 42400164
Back pain 38.15 11.67 984 220045 140792 42259514
Atrial flutter 38.04 11.67 21 221008 17230 42383076
Prescribed overdose 38.02 11.67 10 221019 12917 42387389
Haemorrhage intracranial 37.80 11.67 21 221008 17171 42383135
Obstruction 37.72 11.67 62 220967 3041 42397265
Amyotrophic lateral sclerosis 37.55 11.67 37 220992 1075 42399231
Pulmonary sarcoidosis 37.53 11.67 32 220997 768 42399538
Allergic oedema 37.52 11.67 15 221014 75 42400231
Adverse food reaction 37.40 11.67 10 221019 7 42400299
Irritability 37.24 11.67 55 220974 28073 42372233
Wound complication 37.23 11.67 57 220972 2630 42397676
Mycobacterium marinum infection 37.21 11.67 27 221002 508 42399798
Polychondritis 37.11 11.67 24 221005 371 42399935
Aspartate aminotransferase increased 37.01 11.67 241 220788 76922 42323384
Staphylococcal infection 36.94 11.67 327 220702 37316 42362990
Blood pressure diastolic decreased 36.93 11.67 5 221024 10370 42389936
Legionella infection 36.84 11.67 28 221001 567 42399739
Spondylitis 36.75 11.67 43 220986 1525 42398781
Venous injury 36.57 11.67 23 221006 338 42399968
Prescribed underdose 36.49 11.67 5 221024 10277 42390029
Double stranded DNA antibody positive 36.33 11.67 19 221010 192 42400114
Nausea 36.32 11.67 1685 219344 395114 42005192
Hepatic encephalopathy 36.28 11.67 20 221009 16422 42383884
Cytomegalovirus infection reactivation 36.18 11.67 7 221022 11171 42389135
Pulmonary arterial hypertension 36.05 11.67 5 221024 10182 42390124
Seminoma 36.02 11.67 22 221007 306 42400000
Acute hepatic failure 35.92 11.67 22 221007 17051 42383255
Antisynthetase syndrome 35.79 11.67 17 221012 137 42400169
Status epilepticus 35.77 11.67 18 221011 15560 42384746
Influenza like illness 35.71 11.67 285 220744 31555 42368751
Gastrointestinal pain 35.71 11.67 74 220955 4341 42395965
Terminal insomnia 35.62 11.67 33 220996 886 42399420
Pelvic pain 35.56 11.67 62 220967 3192 42397114
Troponin increased 35.54 11.67 28 221001 19034 42381272
Urinary tract infection 35.54 11.67 336 220693 98948 42301358
Therapeutic response shortened 35.54 11.67 152 220877 13402 42386904
Adenocarcinoma 35.51 11.67 49 220980 2055 42398251
Blood lactate dehydrogenase increased 35.51 11.67 50 220979 26031 42374275
Renal neoplasm 35.49 11.67 41 220988 1434 42398872
Post procedural swelling 35.42 11.67 19 221010 203 42400103
Hypogammaglobulinaemia 35.35 11.67 9 221020 11882 42388424
End stage renal disease 35.30 11.67 21 221008 16537 42383769
Pain of skin 35.22 11.67 107 220922 7973 42392333
Psychomotor hyperactivity 35.17 11.67 7 221022 10951 42389355
Appendicectomy 35.04 11.67 41 220988 1454 42398852
Tendonitis 34.99 11.67 122 220907 9772 42390534
Post procedural fistula 34.88 11.67 16 221013 118 42400188
Jaundice 34.80 11.67 80 220949 34509 42365797
Malignant melanoma stage I 34.74 11.67 15 221014 94 42400212
Anal fissure 34.66 11.67 81 220948 5158 42395148
Heart rate increased 34.65 11.67 150 220879 53105 42347201
Tropical infectious disease 34.51 11.67 12 221017 37 42400269
Erythema nodosum 34.18 11.67 45 220984 1803 42398503
Lung cancer metastatic 34.08 11.67 58 220971 2928 42397378
Dyspnoea exertional 34.02 11.67 139 220890 50009 42350297
Posterior reversible encephalopathy syndrome 33.95 11.67 12 221017 12809 42387497
Injury associated with device 33.90 11.67 39 220990 1358 42398948
Proctalgia 33.85 11.67 97 220932 6996 42393310
Respiratory symptom 33.81 11.67 8 221021 11098 42389208
X-ray abnormal 33.72 11.67 25 221004 487 42399819
Eosinophilic granulomatosis with polyangiitis 33.69 11.67 3 221026 8635 42391671
Antibiotic therapy 33.60 11.67 15 221014 103 42400203
Stomatitis 33.55 11.67 404 220625 49925 42350381
Poisoning deliberate 33.54 11.67 6 221023 10128 42390178
Pathogen resistance 33.40 11.67 9 221020 11441 42388865
Paternal drugs affecting foetus 33.37 11.67 12 221017 42 42400264
Oligoarthritis 33.34 11.67 18 221011 195 42400111
Incisional hernia 33.33 11.67 39 220990 1383 42398923
Abdominal hernia 33.12 11.67 58 220971 2997 42397309
Plasmablastic lymphoma 33.10 11.67 27 221002 608 42399698
Hypernatraemia 33.07 11.67 6 221023 10026 42390280
Bone marrow oedema 33.05 11.67 31 220998 846 42399460
Paraesthesia 33.00 11.67 550 220479 72909 42327397
Haemoglobin decreased 32.87 11.67 486 220543 131985 42268321
Musculoskeletal discomfort 32.78 11.67 116 220913 9360 42390946
Bronchospasm 32.55 11.67 13 221016 12872 42387434
Arthritis enteropathic 32.47 11.67 16 221013 141 42400165
Skin injury 32.42 11.67 53 220976 2588 42397718
Substance abuse 32.40 11.67 4 221025 8901 42391405
Blood potassium increased 32.38 11.67 29 221000 18507 42381799
Sensitivity to weather change 32.14 11.67 46 220983 1997 42398309
Fibromyalgia 32.14 11.67 66 220963 3847 42396459
Intervertebral disc annular tear 32.12 11.67 10 221019 19 42400287
Limb traumatic amputation 32.11 11.67 11 221018 32 42400274
Oliguria 31.96 11.67 5 221024 9308 42390998
COVID-19 pneumonia 31.92 11.67 39 220990 21574 42378732
Pancreatitis acute 31.89 11.67 80 220949 33484 42366822
Parosmia 31.81 11.67 100 220929 7591 42392715
Oral surgery 31.78 11.67 26 221003 588 42399718
Lymphopenia 31.75 11.67 39 220990 21524 42378782
Colostomy 31.71 11.67 26 221003 590 42399716
Surgical failure 31.67 11.67 15 221014 120 42400186
Lymphadenitis 31.65 11.67 51 220978 2460 42397846
Tonsillitis 31.58 11.67 54 220975 2737 42397569
Spinal osteoarthritis 31.50 11.67 108 220921 8578 42391728
Pseudopolyposis 31.29 11.67 13 221016 73 42400233
Normal newborn 31.22 11.67 21 221008 348 42399958
Seronegative arthritis 31.10 11.67 35 220994 1189 42399117
Tongue disorder 31.10 11.67 79 220950 5304 42395002
Nephropathy toxic 31.06 11.67 25 221004 16813 42383493
Nail psoriasis 31.05 11.67 15 221014 126 42400180
Lymphadenopathy mediastinal 31.04 11.67 58 220971 3153 42397153
Heart rate decreased 31.02 11.67 92 220937 36440 42363866
Large intestinal ulcer 31.01 11.67 50 220979 2413 42397893
Acute respiratory distress syndrome 30.81 11.67 69 220960 30039 42370267
Hepatic enzyme abnormal 30.71 11.67 61 220968 3471 42396835
Physical disability 30.69 11.67 43 220986 1830 42398476
Thymoma benign 30.68 11.67 12 221017 56 42400250
Adenocarcinoma of colon 30.56 11.67 64 220965 3783 42396523
Spinal cord injury cervical 30.34 11.67 19 221010 277 42400029
Skin ulcer 30.28 11.67 232 220797 25369 42374937
Tuberculosis gastrointestinal 30.25 11.67 18 221011 238 42400068
Progressive multifocal leukoencephalopathy 30.20 11.67 11 221018 11525 42388781
Spondyloarthropathy 30.10 11.67 30 220999 884 42399422
Hepatitis cholestatic 30.06 11.67 7 221022 9817 42390489
Acidosis 30.03 11.67 13 221016 12266 42388040
Blood sodium decreased 29.87 11.67 30 220999 18132 42382174
Intestinal cyst 29.87 11.67 7 221022 0 42400306
Rheumatic disorder 29.77 11.67 26 221003 645 42399661
Carpal tunnel syndrome 29.65 11.67 79 220950 5460 42394846
Precancerous skin lesion 29.49 11.67 25 221004 595 42399711
Hypothermia 29.43 11.67 14 221015 12501 42387805
Sepsis 29.32 11.67 798 220231 198536 42201770
Thymoma 29.25 11.67 15 221014 145 42400161
Cell marker increased 29.18 11.67 22 221007 440 42399866
Second primary malignancy 28.95 11.67 7 221022 9568 42390738
Aplastic anaemia 28.90 11.67 14 221015 12370 42387936
Anhedonia 28.88 11.67 3 221026 7637 42392669
Leukocytosis 28.86 11.67 70 220959 29638 42370668
Influenza 28.85 11.67 468 220561 61707 42338599
Renal colic 28.84 11.67 44 220985 2024 42398282
Rectal ulcer 28.77 11.67 33 220996 1145 42399161
Skin disorder 28.77 11.67 168 220861 16776 42383530
Enterovesical fistula 28.76 11.67 30 220999 934 42399372
Anal hypoaesthesia 28.63 11.67 8 221021 8 42400298
Ill-defined disorder 28.60 11.67 163 220866 16133 42384173
Joint warmth 28.57 11.67 25 221004 622 42399684
Gingival pain 28.55 11.67 103 220926 8391 42391915
Superficial spreading melanoma stage unspecified 28.49 11.67 17 221012 226 42400080
Renal injury 28.48 11.67 14 221015 12266 42388040
Cerebral haemorrhage 28.35 11.67 105 220924 38861 42361445
Fatigue 28.27 11.67 1913 219116 433728 41966578
Glomerulonephritis 28.18 11.67 49 220980 2517 42397789
Bladder transitional cell carcinoma stage II 28.18 11.67 11 221018 51 42400255
Anorectal swelling 28.15 11.67 8 221021 9 42400297
Gout 28.13 11.67 65 220964 27990 42372316
Sarcoid-like reaction 28.10 11.67 13 221016 98 42400208
Urinary incontinence 28.07 11.67 43 220986 21625 42378681
Periumbilical abscess 27.96 11.67 12 221017 74 42400232
Haematemesis 27.90 11.67 73 220956 30126 42370180
Disturbance in attention 27.75 11.67 72 220957 29794 42370512
Electrocardiogram abnormal 27.72 11.67 9 221020 10136 42390170
Ileocolectomy 27.70 11.67 8 221021 10 42400296
Pharyngitis streptococcal 27.68 11.67 62 220967 3838 42396468
Gastrointestinal erosion 27.60 11.67 21 221008 426 42399880
DNA antibody positive 27.51 11.67 11 221018 55 42400251
Dysplasia 27.51 11.67 31 220998 1055 42399251
Anaphylactic reaction 27.44 11.67 121 220908 42622 42357684
Wound 27.32 11.67 167 220862 16950 42383356
Guttate psoriasis 27.29 11.67 23 221006 543 42399763
Haematoma 27.24 11.67 66 220963 27957 42372349
Renal tubular necrosis 27.23 11.67 33 220996 18321 42381985
Arrhythmia 27.19 11.67 112 220917 40205 42360101
Wrong technique in device usage process 26.90 11.67 50 220979 2707 42397599
Acute graft versus host disease 26.89 11.67 5 221024 8210 42392096
Sleep disorder 26.89 11.67 143 220886 47952 42352354
Pleurisy 26.87 11.67 74 220955 5216 42395090
Face oedema 26.86 11.67 19 221010 13647 42386659
Coagulopathy 26.82 11.67 46 220983 22116 42378190
Central nervous system inflammation 26.80 11.67 16 221013 213 42400093
Arthropod bite 26.74 11.67 55 220974 3209 42397097
Glycosylated haemoglobin increased 26.71 11.67 17 221012 12907 42387399
Infected fistula 26.67 11.67 16 221013 215 42400091
Glioblastoma 26.63 11.67 35 220994 1400 42398906
Product substitution 26.59 11.67 10 221019 41 42400265
Mucormycosis 26.51 11.67 3 221026 7140 42393166
Psoas abscess 26.42 11.67 27 221002 820 42399486
Pulmonary haemorrhage 26.42 11.67 13 221016 11384 42388922
Weight decreased 26.40 11.67 1325 219704 206623 42193683
Non-Hodgkin's lymphoma 26.40 11.67 35 220994 1412 42398894
Muscle spasms 26.37 11.67 608 220421 85436 42314870
Ileal perforation 26.16 11.67 30 220999 1041 42399265
Jejunal stenosis 26.15 11.67 11 221018 64 42400242
Neuralgia 26.06 11.67 59 220970 25588 42374718
Bacteraemia 25.94 11.67 57 220972 24983 42375323
Short-bowel syndrome 25.92 11.67 18 221011 315 42399991
Acquired hydrocele 25.88 11.67 12 221017 91 42400215
Hyperlipidaemia 25.73 11.67 45 220984 21471 42378835
Laryngeal cancer 25.72 11.67 25 221004 714 42399592
Drug dose omission by device 25.71 11.67 78 220951 5808 42394498
Palmoplantar pustulosis 25.71 11.67 21 221008 474 42399832
Ejection fraction decreased 25.68 11.67 47 220982 22040 42378266
Anal ulcer 25.61 11.67 31 220998 1140 42399166
Cytomegalovirus infection 25.56 11.67 84 220945 32222 42368084
Lower gastrointestinal haemorrhage 25.56 11.67 12 221017 10796 42389510
Pleuropericarditis 25.44 11.67 18 221011 325 42399981
Bursitis infective staphylococcal 25.43 11.67 8 221021 16 42400290
Shock haemorrhagic 25.40 11.67 28 221001 16214 42384092
Stoma complication 25.35 11.67 22 221007 541 42399765
Colostomy closure 25.34 11.67 10 221019 48 42400258
Haemodynamic instability 25.29 11.67 17 221012 12540 42387766
Tenderness 25.15 11.67 102 220927 8781 42391525
Electrolyte imbalance 25.11 11.67 31 220998 17070 42383236
Postoperative wound complication 25.09 11.67 23 221006 609 42399697
Respiratory rate increased 25.07 11.67 13 221016 11049 42389257
Prostate cancer 24.97 11.67 347 220682 44296 42356010
Eye inflammation 24.94 11.67 53 220976 3165 42397141
Arthrodesis 24.75 11.67 22 221007 559 42399747
Small intestine adenocarcinoma 24.60 11.67 15 221014 208 42400098
Rhinitis 24.54 11.67 125 220904 11852 42388454
Limb operation 24.49 11.67 28 221001 968 42399338
Osteonecrosis of jaw 24.49 11.67 38 220991 19011 42381295
Rheumatoid lung 24.47 11.67 27 221002 897 42399409
Kidney infection 24.39 11.67 84 220945 6686 42393620
Hypopnoea 24.34 11.67 93 220936 7789 42392517
Stent placement 24.33 11.67 72 220957 5288 42395018
Aplasia pure red cell 24.25 11.67 4 221025 7162 42393144
Chronic inflammatory demyelinating polyradiculoneuropathy 24.21 11.67 31 220998 1208 42399098
Cartilage injury 24.17 11.67 22 221007 577 42399729
Micturition urgency 24.11 11.67 16 221013 11882 42388424
Spinal disorder 24.10 11.67 65 220964 4526 42395780
Product storage error 24.06 11.67 118 220911 11022 42389284
Clostridium difficile colitis 24.03 11.67 46 220983 21206 42379100
Granulocytopenia 24.01 11.67 4 221025 7110 42393196
Renal cell carcinoma 23.99 11.67 73 220956 5444 42394862
Body temperature increased 23.96 11.67 43 220986 20315 42379991
Myositis 23.95 11.67 25 221004 14841 42385465
Atrial septal defect acquired 23.94 11.67 8 221021 21 42400285
Granuloma skin 23.91 11.67 30 220999 1145 42399161
Alcohol poisoning 23.91 11.67 90 220939 7484 42392822
Hot flush 23.88 11.67 50 220979 22301 42378005
Intra-abdominal fluid collection 23.88 11.67 34 220995 1469 42398837
Suicidal ideation 23.82 11.67 149 220880 48012 42352294
Gastrointestinal tract adenoma 23.79 11.67 17 221012 312 42399994
Osteopenia 23.59 11.67 79 220950 6199 42394107
Prerenal failure 23.58 11.67 44 220985 2389 42397917
Brain oedema 23.55 11.67 30 220999 16297 42384009
Cirrhosis alcoholic 23.49 11.67 25 221004 797 42399509
Abdominal wall abscess 23.49 11.67 23 221006 663 42399643
Pelvic abscess 23.40 11.67 28 221001 1017 42399289
Potentiating drug interaction 23.30 11.67 3 221026 6465 42393841
Toxic encephalopathy 23.26 11.67 4 221025 6949 42393357
Euphoric mood 23.23 11.67 3 221026 6450 42393856
Alopecia universalis 23.23 11.67 13 221016 152 42400154
Grip strength decreased 23.22 11.67 55 220974 3533 42396773
Tendon rupture 23.04 11.67 93 220936 7990 42392316
Inflammatory pain 22.97 11.67 21 221008 554 42399752
Myelitis 22.83 11.67 28 221001 1044 42399262
Large intestinal obstruction 22.81 11.67 36 220993 1706 42398600
Skin papilloma 22.80 11.67 47 220982 2747 42397559
Gynaecomastia 22.76 11.67 19 221010 12548 42387758
Musculoskeletal disorder 22.74 11.67 81 220948 6557 42393749
Anuria 22.71 11.67 16 221013 11516 42388790
Umbilical hernia 22.69 11.67 71 220958 5376 42394930
Hypovolaemia 22.53 11.67 16 221013 11469 42388837
Paracoccidioides infection 22.48 11.67 10 221019 68 42400238
Hypersensitivity vasculitis 22.39 11.67 51 220978 3193 42397113
C-reactive protein decreased 22.38 11.67 41 220988 2195 42398111
Pulmonary vasculitis 22.35 11.67 3 221026 6263 42394043
Polyuria 22.34 11.67 12 221017 9999 42390307
Thymus disorder 22.33 11.67 15 221014 248 42400058
Dyschezia 22.17 11.67 36 220993 1748 42398558
Hyperthyroidism 22.12 11.67 25 221004 14316 42385990
Peritoneal tuberculosis 22.09 11.67 17 221012 351 42399955
Acute myocardial infarction 22.04 11.67 194 220835 57971 42342335
Meningitis listeria 22.02 11.67 22 221007 650 42399656
Rash papular 21.96 11.67 120 220909 11691 42388615
BK virus infection 21.96 11.67 9 221020 8775 42391531
Joint dislocation 21.92 11.67 61 220968 4326 42395980
Parkinsonism 21.92 11.67 14 221015 10609 42389697
Balance disorder 21.74 11.67 151 220878 47494 42352812
Colonic abscess 21.72 11.67 22 221007 661 42399645
Prothrombin time prolonged 21.65 11.67 11 221018 9458 42390848
Heparin-induced thrombocytopenia 21.63 11.67 4 221025 6593 42393713
Small intestinal anastomosis 21.63 11.67 7 221022 16 42400290
CSF oligoclonal band present 21.47 11.67 6 221023 6 42400300
Bronchial neoplasm 21.47 11.67 6 221023 6 42400300
Chronic idiopathic pain syndrome 21.46 11.67 12 221017 140 42400166
Abnormal dreams 21.46 11.67 8 221021 8263 42392043
Hypovolaemic shock 21.44 11.67 9 221020 8650 42391656
Antiphospholipid syndrome 21.43 11.67 21 221008 606 42399700
Adrenal insufficiency 21.36 11.67 41 220988 18883 42381423
Decubitus ulcer 21.35 11.67 14 221015 10463 42389843
Glaucomatocyclitic crises 21.34 11.67 5 221024 0 42400306
Salivary gland adenoma 21.34 11.67 5 221024 0 42400306
Proctectomy 21.24 11.67 12 221017 143 42400163
Acute generalised exanthematous pustulosis 21.18 11.67 9 221020 8586 42391720
Anxiety 21.14 11.67 461 220568 118099 42282207
Cardiac operation 21.11 11.67 54 220975 3641 42396665
Skin laceration 21.09 11.67 135 220894 13923 42386383
Fine motor skill dysfunction 21.09 11.67 40 220989 2199 42398107
Bladder neoplasm 20.93 11.67 32 220997 1475 42398831
Product dose omission issue 20.90 11.67 625 220404 153740 42246566
Coronary artery disease 20.88 11.67 178 220851 53542 42346764
Intentional self-injury 20.84 11.67 29 221000 15173 42385133
Thyroid cancer 20.84 11.67 35 220994 1748 42398558
Haemorrhage 20.80 11.67 207 220822 60356 42339950
Staphylococcal abscess 20.79 11.67 21 221008 629 42399677
Blood iron decreased 20.71 11.67 76 220953 6242 42394064
Low birth weight baby 20.70 11.67 13 221016 9942 42390364
Investigation abnormal 20.68 11.67 21 221008 633 42399673
Mental impairment 20.66 11.67 20 221009 12297 42388009
Melanocytic naevus 20.61 11.67 47 220982 2945 42397361
Panniculitis 20.59 11.67 39 220990 2142 42398164
Pulseless electrical activity 20.52 11.67 9 221020 8428 42391878
Drain placement 20.50 11.67 10 221019 86 42400220
Cutaneous lymphoma 20.47 11.67 11 221018 118 42400188
Productive cough 20.43 11.67 170 220859 51397 42348909
Mania 20.29 11.67 15 221014 10532 42389774
Cyanosis 20.28 11.67 29 221000 15002 42385304
Obsessive-compulsive disorder 20.25 11.67 5 221024 6738 42393568
Brain neoplasm 20.24 11.67 52 220977 3516 42396790
Respiratory syncytial virus infection 20.16 11.67 6 221023 7146 42393160
Hiccups 20.14 11.67 20 221009 12151 42388155
Nerve compression 20.12 11.67 56 220973 3972 42396334
Extradural abscess 20.01 11.67 25 221004 950 42399356
Haemolytic anaemia 19.98 11.67 20 221009 12107 42388199
Eczema 19.90 11.67 267 220762 33819 42366487
Epstein-Barr virus antibody positive 19.89 11.67 15 221014 300 42400006
Breath sounds abnormal 19.86 11.67 20 221009 12073 42388233
Injection site paraesthesia 19.83 11.67 12 221017 164 42400142
Gastrointestinal dilation procedure 19.80 11.67 7 221022 23 42400283
Immobile 19.80 11.67 45 220984 2813 42397493
Thyroiditis subacute 19.78 11.67 9 221020 65 42400241
Acrochordon 19.72 11.67 18 221011 474 42399832
Hepatitis acute 19.68 11.67 11 221018 8964 42391342
Abscess bacterial 19.67 11.67 13 221016 209 42400097
Joint injury 19.65 11.67 137 220892 14539 42385767
Hypercalcaemia 19.63 11.67 40 220989 18018 42382288
Product administration error 19.63 11.67 41 220988 18302 42382004
Drug resistance 19.61 11.67 101 220928 34147 42366159
Autoimmune haemolytic anaemia 19.56 11.67 3 221026 5668 42394638
Tonsillar disorder 19.56 11.67 17 221012 419 42399887
Stress 19.47 11.67 330 220699 43882 42356424
Dizziness postural 19.47 11.67 8 221021 7787 42392519
Subarachnoid haemorrhage 19.45 11.67 28 221001 14444 42385862
Ulcer 19.45 11.67 149 220880 16292 42384014
Cutaneous B-cell lymphoma 19.44 11.67 9 221020 68 42400238
Central nervous system vasculitis 19.40 11.67 20 221009 614 42399692
Haemolysis 19.29 11.67 13 221016 9576 42390730
Nasal congestion 19.24 11.67 83 220946 29418 42370888
Tardive dyskinesia 19.17 11.67 6 221023 6918 42393388
Right ventricular failure 19.16 11.67 13 221016 9542 42390764
Dermal cyst 19.13 11.67 36 220993 1967 42398339
Stomal hernia 19.12 11.67 16 221013 374 42399932
Product quality issue 19.11 11.67 40 220989 17842 42382464
Malignant polyp 19.00 11.67 5 221024 3 42400303
Streptococcal abscess 19.00 11.67 5 221024 3 42400303
Paranoia 18.98 11.67 27 221002 13999 42386307
Decreased immune responsiveness 18.96 11.67 37 220992 2078 42398228
Computerised tomogram abdomen abnormal 18.95 11.67 7 221022 27 42400279
Axillary mass 18.94 11.67 13 221016 223 42400083
Dental caries 18.93 11.67 62 220967 4810 42395496
Abnormal faeces 18.91 11.67 54 220975 3887 42396419
Injection site haematoma 18.89 11.67 35 220994 1890 42398416
Shoulder operation 18.86 11.67 30 220999 1431 42398875
Tooth infection 18.86 11.67 87 220942 7924 42392382
Hepatic enzyme increased 18.83 11.67 338 220691 45446 42354860
Cholangiocarcinoma 18.82 11.67 32 220997 1614 42398692
Precancerous cells present 18.82 11.67 8 221021 48 42400258
Dyshidrotic eczema 18.81 11.67 12 221017 181 42400125
Nocturia 18.81 11.67 21 221008 12091 42388215
Shoulder arthroplasty 18.76 11.67 22 221007 782 42399524
Priapism 18.76 11.67 5 221024 6402 42393904
Phototherapy 18.75 11.67 7 221022 28 42400278
Stoma site ulcer 18.75 11.67 7 221022 28 42400278
Gait inability 18.74 11.67 191 220838 22642 42377664
Post procedural discharge 18.72 11.67 15 221014 329 42399977
Abdominal operation 18.72 11.67 11 221018 142 42400164
Gastrointestinal dysplasia 18.71 11.67 10 221019 106 42400200
Electromyogram abnormal 18.68 11.67 8 221021 49 42400257
Lipoma 18.68 11.67 37 220992 2101 42398205
Blood glucose decreased 18.63 11.67 28 221001 14191 42386115
Oropharyngeal pain 18.62 11.67 317 220712 42193 42358113
Acne fulminans 18.57 11.67 14 221015 280 42400026
Enterococcal infection 18.56 11.67 21 221008 12018 42388288
Gastroenterostomy 18.55 11.67 8 221021 50 42400256
Brain natriuretic peptide increased 18.51 11.67 6 221023 6764 42393542
Spinal operation 18.50 11.67 56 220973 4164 42396142
Stricturoplasty 18.42 11.67 5 221024 4 42400302
Polyarteritis nodosa 18.35 11.67 15 221014 339 42399967
Hypergammaglobulinaemia benign monoclonal 18.28 11.67 16 221013 398 42399908
Epstein-Barr virus associated lymphoma 18.26 11.67 25 221004 1041 42399265
Joint instability 18.24 11.67 18 221011 524 42399782
Serositis 18.19 11.67 14 221015 289 42400017
Foreign body in gastrointestinal tract 18.19 11.67 7 221022 31 42400275
Ataxia 18.14 11.67 35 220994 16090 42384216
Small intestine ulcer 18.12 11.67 18 221011 528 42399778
Neck deformity 18.08 11.67 10 221019 114 42400192
Cutaneous sarcoidosis 18.01 11.67 11 221018 153 42400153
Incorrect route of product administration 18.01 11.67 65 220964 24240 42376066
Red blood cell sedimentation rate 18.00 11.67 25 221004 1055 42399251
Foot operation 17.94 11.67 21 221008 745 42399561
Atypical fibroxanthoma 17.94 11.67 12 221017 197 42400109
Neuritis 17.94 11.67 5 221024 6215 42394091
Bladder neck operation 17.90 11.67 5 221024 5 42400301
Keratoacanthoma 17.87 11.67 23 221006 901 42399405
Hospice care 17.86 11.67 11 221018 8502 42391804
Rebound psoriasis 17.83 11.67 11 221018 156 42400150
Blindness unilateral 17.82 11.67 65 220964 5323 42394983
Carbon dioxide abnormal 17.79 11.67 14 221015 299 42400007
Chromaturia 17.74 11.67 35 220994 15954 42384352
Transfusion 17.72 11.67 17 221012 10497 42389809
Pneumonia bacterial 17.71 11.67 34 220995 15658 42384648
Blood calcium increased 17.63 11.67 11 221018 8443 42391863
Colon neoplasm 17.63 11.67 18 221011 546 42399760
Anorectal stenosis 17.63 11.67 6 221023 17 42400289
Immune system disorder 17.59 11.67 70 220959 5974 42394332
Aortic aneurysm 17.54 11.67 83 220946 7640 42392666
Extrapulmonary tuberculosis 17.47 11.67 11 221018 162 42400144
Abdominal pain lower 17.46 11.67 115 220914 11977 42388329
Intestinal mucosal atrophy 17.42 11.67 5 221024 6 42400300
Systemic lupus erythematosus rash 17.41 11.67 11 221018 163 42400143
Ligament rupture 17.36 11.67 28 221001 1352 42398954
Ureterolithiasis 17.35 11.67 40 220989 2524 42397782
Neoplasm prostate 17.33 11.67 13 221016 258 42400048
Ventricular hypokinesia 17.30 11.67 7 221022 6877 42393429
Cutaneous tuberculosis 17.29 11.67 10 221019 125 42400181
Alcoholic liver disease 17.29 11.67 18 221011 559 42399747
Immune reconstitution inflammatory syndrome associated tuberculosis 17.19 11.67 18 221011 563 42399743
Speech disorder 17.17 11.67 85 220944 29036 42371270
Myopathy 17.17 11.67 28 221001 13733 42386573
Hepatic fibrosis 17.16 11.67 60 220969 4812 42395494
Skin cancer 17.15 11.67 110 220919 11352 42388954
Treatment delayed 17.12 11.67 11 221018 168 42400138
Enzyme abnormality 17.11 11.67 13 221016 263 42400043
Infectious mononucleosis 17.10 11.67 20 221009 709 42399597
Tuberculosis of central nervous system 17.09 11.67 12 221017 214 42400092
Marginal zone lymphoma 17.09 11.67 10 221019 128 42400178
Cervical spinal stenosis 17.07 11.67 28 221001 1371 42398935
Restless arm syndrome 17.07 11.67 4 221025 0 42400306
Gallbladder cancer metastatic 17.07 11.67 4 221025 0 42400306
Post viral fatigue syndrome 17.07 11.67 4 221025 0 42400306
Inflammatory marker test 17.07 11.67 4 221025 0 42400306
Vena cava embolism 17.07 11.67 4 221025 0 42400306
PASH syndrome 17.07 11.67 4 221025 0 42400306
Ocular fistula 17.07 11.67 4 221025 0 42400306
Sweat gland infection 17.07 11.67 4 221025 0 42400306
Scab 17.05 11.67 68 220961 5810 42394496
Visual evoked potentials abnormal 17.00 11.67 8 221021 63 42400243
Angiolymphoid hyperplasia with eosinophilia 16.95 11.67 10 221019 130 42400176
Intestinal haemorrhage 16.92 11.67 52 220977 3899 42396407
Gastrointestinal adenocarcinoma 16.89 11.67 8 221021 64 42400242
Type 2 diabetes mellitus 16.87 11.67 158 220871 18313 42381993
Renal amyloidosis 16.79 11.67 9 221020 96 42400210
Mesenteritis 16.75 11.67 7 221022 40 42400266
Heavy exposure to ultraviolet light 16.75 11.67 7 221022 40 42400266
Pancreatic duct stenosis 16.74 11.67 11 221018 175 42400131
Neutrophil count increased 16.72 11.67 50 220979 19754 42380552
Intestinal operation 16.71 11.67 12 221017 222 42400084
Electrocardiogram ST segment elevation 16.71 11.67 5 221024 5934 42394372
Vitiligo 16.71 11.67 26 221003 1217 42399089
Perineal fistula 16.69 11.67 6 221023 21 42400285
Ocular sarcoidosis 16.69 11.67 6 221023 21 42400285
Gastric bypass 16.66 11.67 13 221016 274 42400032
Animal bite 16.63 11.67 21 221008 807 42399499
Taste disorder 16.63 11.67 17 221012 10190 42390116
Small intestine carcinoma 16.62 11.67 19 221010 657 42399649
Signet-ring cell carcinoma 16.60 11.67 5 221024 8 42400298
Multifocal motor neuropathy 16.57 11.67 10 221019 136 42400170
Bile duct stone 16.49 11.67 42 220987 2825 42397481
Exposure to toxic agent 16.48 11.67 3 221026 5001 42395305
Abscess rupture 16.48 11.67 8 221021 68 42400238
B-cell lymphoma stage IV 16.48 11.67 8 221021 68 42400238
Tricuspid valve incompetence 16.47 11.67 20 221009 11093 42389213
Behaviour disorder 16.42 11.67 8 221021 7046 42393260
Treatment noncompliance 16.41 11.67 121 220908 37551 42362755
Underdose 16.40 11.67 39 220990 16627 42383679
Paradoxical drug reaction 16.39 11.67 58 220971 4680 42395626
Rectal cancer 16.39 11.67 37 220992 2303 42398003
Transient ischaemic attack 16.36 11.67 105 220924 33634 42366672
Cutaneous symptom 16.34 11.67 15 221014 398 42399908
Genital hypoaesthesia 16.30 11.67 12 221017 231 42400075
Soft tissue swelling 16.30 11.67 20 221009 746 42399560
Dry skin 16.27 11.67 166 220863 48172 42352134
Pneumonia 16.27 11.67 1929 219100 420220 41980086
Nasal sinus cancer 16.27 11.67 6 221023 23 42400283
Inflammation of wound 16.27 11.67 6 221023 23 42400283
Chest discomfort 16.25 11.67 232 220797 63384 42336922
Thirst 16.21 11.67 14 221015 9094 42391212
Mydriasis 16.20 11.67 13 221016 8757 42391549
Infusion site pain 16.20 11.67 4 221025 5391 42394915
Meningioma benign 16.20 11.67 7 221022 44 42400262
Failure to thrive 16.15 11.67 15 221014 9407 42390899
Angina pectoris 16.15 11.67 102 220927 32794 42367512
Colon operation 16.09 11.67 12 221017 236 42400070
Ageusia 16.05 11.67 22 221007 11583 42388723
Retroperitoneal abscess 16.04 11.67 14 221015 347 42399959
Methaemoglobinaemia 16.00 11.67 5 221024 5769 42394537
Abdominal mass 15.90 11.67 37 220992 2349 42397957
Cardiac failure acute 15.86 11.67 29 221000 13604 42386702
Ileus paralytic 15.86 11.67 10 221019 7631 42392675
Groin abscess 15.85 11.67 21 221008 847 42399459
Hyperplasia 15.84 11.67 19 221010 692 42399614
Ankle operation 15.82 11.67 13 221016 296 42400010
Exposure to communicable disease 15.82 11.67 11 221018 193 42400113
Blood cholesterol increased 15.80 11.67 78 220951 26663 42373643
Hypoalbuminaemia 15.78 11.67 36 220993 15574 42384732
Urine output decreased 15.66 11.67 20 221009 10853 42389453
Contraindication to medical treatment 15.66 11.67 21 221008 857 42399449
Brain herniation 15.65 11.67 3 221026 4820 42395486
Angioimmunoblastic T-cell lymphoma 15.65 11.67 14 221015 359 42399947
Aspergillus infection 15.63 11.67 37 220992 15800 42384506
Schizophrenia 15.62 11.67 19 221010 10531 42389775
Testicular seminoma (pure) 15.58 11.67 11 221018 198 42400108
Postoperative thrombosis 15.57 11.67 7 221022 49 42400257
Bacterial infection 15.52 11.67 83 220946 27796 42372510
Mesenteric abscess 15.51 11.67 6 221023 27 42400279
Incorrect dose administered by device 15.46 11.67 40 220989 2716 42397590
Granulomatous dermatitis 15.46 11.67 13 221016 306 42400000
Infection susceptibility increased 15.45 11.67 23 221006 1035 42399271
Product preparation error 15.45 11.67 3 221026 4775 42395531
Therapeutic response changed 15.43 11.67 17 221012 564 42399742
Spinal cord abscess 15.36 11.67 15 221014 431 42399875
Dialysis 15.32 11.67 24 221005 11962 42388344
Hyperthermia 15.30 11.67 26 221003 12548 42387758
General symptom 15.24 11.67 23 221006 1048 42399258
Rectal lesion 15.22 11.67 7 221022 52 42400254
Psoriasis area severity index increased 15.20 11.67 8 221021 82 42400224
Chronic granulomatous disease 15.17 11.67 6 221023 29 42400277
Product complaint 15.15 11.67 6 221023 5971 42394335
Anastomotic complication 15.13 11.67 15 221014 439 42399867
Intestinal adenocarcinoma 15.12 11.67 8 221021 83 42400223
Tuberculosis of eye 15.11 11.67 7 221022 53 42400253
Injection site discharge 15.06 11.67 16 221013 509 42399797
Bronchopulmonary aspergillosis 15.04 11.67 51 220978 19378 42380928
Synovectomy 15.03 11.67 8 221021 84 42400222
Dermatitis exfoliative generalised 15.03 11.67 65 220964 5759 42394547
Respiratory acidosis 15.02 11.67 7 221022 6324 42393982
Campylobacter gastroenteritis 15.01 11.67 23 221006 1062 42399244
Testicular seminoma (pure) stage I 15.01 11.67 6 221023 30 42400276
Angiotensin converting enzyme increased 14.95 11.67 8 221021 85 42400221
Inappropriate schedule of product administration 14.95 11.67 624 220405 95278 42305028
Deep vein thrombosis 14.93 11.67 513 220516 76444 42323862
Acute myeloid leukaemia 14.90 11.67 62 220967 22194 42378112
Tuberculosis of intrathoracic lymph nodes 14.85 11.67 4 221025 3 42400303
Non-Hodgkin's lymphoma stage IV 14.85 11.67 4 221025 3 42400303
Testicular germ cell cancer 14.85 11.67 4 221025 3 42400303
Alanine aminotransferase increased 14.83 11.67 347 220682 88059 42312247
Blood uric acid increased 14.81 11.67 37 220992 15510 42384796
Erythema multiforme 14.74 11.67 18 221011 9959 42390347
Benign abdominal neoplasm 14.71 11.67 8 221021 88 42400218
Cytomegalovirus chorioretinitis 14.69 11.67 3 221026 4608 42395698
Abdominal discomfort 14.68 11.67 502 220527 74753 42325553
Skin lesion inflammation 14.67 11.67 7 221022 57 42400249
Large intestine anastomosis 14.67 11.67 7 221022 57 42400249
Blood cholesterol abnormal 14.65 11.67 32 220997 1947 42398359
Exostosis 14.65 11.67 63 220966 5568 42394738
Anal skin tags 14.64 11.67 8 221021 89 42400217
Ear infection 14.57 11.67 115 220914 12689 42387617
Intervertebral disc displacement 14.56 11.67 9 221020 128 42400178
Adhesiolysis 14.48 11.67 5 221024 15 42400291
Skin exfoliation 14.44 11.67 299 220730 41254 42359052
Peritonitis bacterial 14.42 11.67 9 221020 6906 42393400
Electrocardiogram Q waves 14.40 11.67 6 221023 34 42400272
Bladder cancer recurrent 14.37 11.67 14 221015 401 42399905
Memory impairment 14.33 11.67 179 220850 50043 42350263
Hypertransaminasaemia 14.33 11.67 16 221013 9211 42391095
Enthesophyte 14.32 11.67 4 221025 4 42400302
Mastoidectomy 14.32 11.67 4 221025 4 42400302
Mycobacterium tuberculosis complex test 14.32 11.67 4 221025 4 42400302
Fibrosing colonopathy 14.32 11.67 4 221025 4 42400302
Allergic hepatitis 14.32 11.67 4 221025 4 42400302
Rehabilitation therapy 14.31 11.67 23 221006 1107 42399199
Myocardial infarction 14.27 11.67 783 220246 123226 42277080
Lung neoplasm 14.22 11.67 55 220974 4633 42395673
Miller Fisher syndrome 14.21 11.67 9 221020 134 42400172
Ventricular dysfunction 14.20 11.67 3 221026 4500 42395806
Limb discomfort 14.16 11.67 114 220915 12653 42387653
Colectomy total 14.16 11.67 13 221016 345 42399961
Rheumatoid factor increased 14.13 11.67 18 221011 698 42399608
Cardiac myxoma 14.11 11.67 6 221023 36 42400270
Granuloma annulare 14.11 11.67 10 221019 181 42400125
Therapeutic response decreased 14.09 11.67 270 220759 36742 42363564
Carditis 14.05 11.67 11 221018 233 42400073
Spinal laminectomy 14.03 11.67 13 221016 349 42399957
Thinking abnormal 14.02 11.67 10 221019 7151 42393155
Omphalitis 14.02 11.67 5 221024 17 42400289
Rectal dysplasia 14.02 11.67 5 221024 17 42400289
Bone giant cell tumour 13.98 11.67 6 221023 37 42400269
Acne conglobata 13.98 11.67 6 221023 37 42400269
SAPHO syndrome 13.98 11.67 14 221015 415 42399891
Bronchiectasis 13.97 11.67 149 220880 17870 42382436
Supraventricular tachycardia 13.90 11.67 27 221002 12381 42387925
Self-consciousness 13.87 11.67 9 221020 140 42400166
Blood parathyroid hormone decreased 13.83 11.67 28 221001 1615 42398691
Nodular melanoma 13.83 11.67 10 221019 187 42400119
Metabolic encephalopathy 13.82 11.67 5 221024 5260 42395046
Bradyphrenia 13.80 11.67 5 221024 5257 42395049
Adenosine deaminase decreased 13.80 11.67 5 221024 18 42400288
Benign neoplasm of prostate 13.80 11.67 5 221024 18 42400288
Alopecia totalis 13.80 11.67 5 221024 18 42400288
Clonal haematopoiesis 13.74 11.67 10 221019 189 42400117
Acute graft versus host disease in skin 13.72 11.67 11 221018 7413 42392893
Short stature 13.68 11.67 14 221015 426 42399880
Liver injury 13.67 11.67 52 220977 19096 42381210
Ventricular hypertrophy 13.65 11.67 4 221025 4812 42395494
Ischaemic stroke 13.63 11.67 64 220965 22169 42378137
Splenectomy 13.60 11.67 14 221015 429 42399877
Pseudomonas infection 13.59 11.67 40 220989 15883 42384423
Hypoxic-ischaemic encephalopathy 13.55 11.67 5 221024 5197 42395109
Pityriasis 13.53 11.67 7 221022 69 42400237
Atrioventricular block 13.52 11.67 18 221011 9597 42390709
Pulse absent 13.52 11.67 8 221021 6319 42393987
Bursitis infective 13.51 11.67 17 221012 651 42399655
Glaucoma 13.50 11.67 81 220948 8167 42392139
Gastric haemorrhage 13.49 11.67 21 221008 10494 42389812
Metastatic gastric cancer 13.49 11.67 9 221020 147 42400159
Blood calcium decreased 13.49 11.67 23 221006 11085 42389221
Onycholysis 13.48 11.67 21 221008 984 42399322
Circumstance or information capable of leading to medication error 13.48 11.67 36 220993 2492 42397814
Osteosarcoma 13.47 11.67 12 221017 306 42400000
Spondylolisthesis 13.46 11.67 19 221010 814 42399492
Ventricular extrasystoles 13.44 11.67 31 220998 13359 42386947
Glomerulonephritis rapidly progressive 13.44 11.67 20 221009 900 42399406
Ocular rosacea 13.43 11.67 4 221025 6 42400300
SLE arthritis 13.43 11.67 4 221025 6 42400300
Large cell lung cancer 13.43 11.67 4 221025 6 42400300
Stitch abscess 13.43 11.67 4 221025 6 42400300
False positive tuberculosis test 13.43 11.67 4 221025 6 42400300
Stoma creation 13.43 11.67 8 221021 106 42400200
Monoclonal gammopathy 13.41 11.67 15 221014 506 42399800
Asphyxia 13.41 11.67 14 221015 8312 42391994
Presyncope 13.40 11.67 65 220964 22322 42377984
Large intestine erosion 13.39 11.67 5 221024 20 42400286
Gallbladder operation 13.38 11.67 16 221013 581 42399725
Ventricular arrhythmia 13.33 11.67 8 221021 6271 42394035
Gastrointestinal anastomotic leak 13.33 11.67 16 221013 583 42399723
Drug level above therapeutic 13.30 11.67 7 221022 5899 42394407
Meningitis tuberculous 13.29 11.67 17 221012 662 42399644
Wrong technique in product usage process 13.28 11.67 302 220727 42333 42357973
Procedural nausea 13.24 11.67 8 221021 109 42400197
Eye irritation 13.23 11.67 24 221005 11294 42389012
Oesophagitis 13.23 11.67 38 220991 15209 42385097
Episcleritis 13.22 11.67 10 221019 201 42400105
Laboratory test 13.20 11.67 5 221024 21 42400285
Corneal neovascularisation 13.20 11.67 7 221022 73 42400233
Cerebral infarction 13.15 11.67 101 220928 31068 42369238
Myocarditis 13.15 11.67 52 220977 18886 42381420
Hernia repair 13.14 11.67 25 221004 1378 42398928
Wrong product administered 13.13 11.67 8 221021 6218 42394088
Syringe issue 13.10 11.67 15 221014 8541 42391765
Nutritional condition abnormal 13.07 11.67 15 221014 521 42399785
Carcinoid tumour pulmonary 13.06 11.67 4 221025 7 42400299
Fistula inflammation 13.06 11.67 4 221025 7 42400299
Fear 13.05 11.67 23 221006 10942 42389364
Small cell lung cancer metastatic 13.04 11.67 13 221016 383 42399923
Device delivery system issue 12.99 11.67 21 221008 1016 42399290
Salmonella sepsis 12.94 11.67 9 221020 158 42400148
Hyperammonaemia 12.93 11.67 13 221016 7853 42392453
Blood loss anaemia 12.92 11.67 19 221010 9717 42390589
Demyelinating polyneuropathy 12.88 11.67 27 221002 1597 42398709
Small intestinal perforation 12.87 11.67 39 220990 2902 42397404
Abscess sterile 12.84 11.67 5 221024 23 42400283
Drug level changed 12.83 11.67 13 221016 391 42399915
Anal polyp 12.80 11.67 3 221026 0 42400306
Lip and/or oral cavity cancer stage 0 12.80 11.67 3 221026 0 42400306
Dermatopathic lymphadenopathy 12.80 11.67 3 221026 0 42400306
Male genital tract fistula 12.80 11.67 3 221026 0 42400306
Amniotic band syndrome 12.80 11.67 3 221026 0 42400306
Mononucleosis heterophile test positive 12.80 11.67 3 221026 0 42400306
Testicular germ cell tumour 12.80 11.67 3 221026 0 42400306
Infected vasculitis 12.80 11.67 3 221026 0 42400306
Lichen nitidus 12.80 11.67 3 221026 0 42400306
DNA antibody 12.80 11.67 3 221026 0 42400306
Pelvic pouch procedure 12.80 11.67 3 221026 0 42400306
Tonsil cancer metastatic 12.80 11.67 3 221026 0 42400306
Endocrine neoplasm 12.80 11.67 3 221026 0 42400306
Duodenal operation 12.80 11.67 3 221026 0 42400306
Diverticular fistula 12.80 11.67 3 221026 0 42400306
Mucosal atrophy 12.80 11.67 7 221022 78 42400228
Injection site nodule 12.78 11.67 32 220997 2129 42398177
Haemorrhoidal haemorrhage 12.78 11.67 3 221026 4185 42396121
Lymph gland infection 12.77 11.67 10 221019 212 42400094
Finger deformity 12.75 11.67 27 221002 1608 42398698
Osteosarcoma recurrent 12.75 11.67 8 221021 117 42400189
Thyroidectomy 12.72 11.67 7 221022 79 42400227
Liver function test increased 12.66 11.67 159 220870 19839 42380467
Blood glucose fluctuation 12.66 11.67 4 221025 4583 42395723
Pyoderma 12.65 11.67 9 221020 164 42400142
Kyphosis 12.65 11.67 24 221005 1320 42398986
Visceral leishmaniasis 12.63 11.67 22 221007 1132 42399174
Myelitis transverse 12.61 11.67 24 221005 1323 42398983
Atrial tachycardia 12.57 11.67 3 221026 4137 42396169
Product prescribing issue 12.56 11.67 10 221019 6763 42393543
Benign neoplasm 12.56 11.67 11 221018 274 42400032
Cubital tunnel syndrome 12.53 11.67 10 221019 218 42400088
Gastric neoplasm 12.50 11.67 7 221022 82 42400224
Cardiac failure chronic 12.49 11.67 19 221010 9582 42390724
Proteinuria 12.48 11.67 69 220960 22914 42377392
Papilloma viral infection 12.47 11.67 17 221012 705 42399601
Blood pressure diastolic increased 12.47 11.67 9 221020 6396 42393910
Body temperature decreased 12.45 11.67 36 220993 14377 42385929
Seminal vesicular disorder 12.40 11.67 4 221025 9 42400297
Muscle fatigue 12.40 11.67 28 221001 1743 42398563
Procedural complication 12.39 11.67 49 220980 4170 42396136
Pulmonary toxicity 12.38 11.67 16 221013 8639 42391667
Acute pulmonary oedema 12.37 11.67 16 221013 8635 42391671
Swollen joint count increased 12.36 11.67 11 221018 280 42400026
Pharyngeal neoplasm 12.35 11.67 5 221024 26 42400280
Epicondylitis 12.34 11.67 14 221015 480 42399826
Connective tissue disorder 12.33 11.67 11 221018 281 42400025
Injection site hypersensitivity 12.30 11.67 13 221016 411 42399895
Eye infection staphylococcal 12.28 11.67 7 221022 85 42400221
Bowel movement irregularity 12.27 11.67 43 220986 3453 42396853
Viral infection 12.26 11.67 174 220855 22309 42377997
Candida infection 12.22 11.67 64 220965 21546 42378760
White matter lesion 12.21 11.67 20 221009 978 42399328
Increased appetite 12.20 11.67 17 221012 8889 42391417
Duodenal stenosis 12.20 11.67 12 221017 348 42399958
Cardiolipin antibody positive 12.19 11.67 5 221024 27 42400279
Fibrosis 12.17 11.67 39 220990 2991 42397315
Urticarial vasculitis 12.14 11.67 7 221022 87 42400219
Cerebral haematoma 12.12 11.67 7 221022 5603 42394703
Benign salivary gland neoplasm 12.11 11.67 4 221025 10 42400296
Injection site anaesthesia 12.11 11.67 4 221025 10 42400296
Hand deformity 12.08 11.67 45 220984 3723 42396583
Toxic skin eruption 12.07 11.67 34 220995 13696 42386610
Cyst rupture 12.07 11.67 7 221022 88 42400218
Benign lung neoplasm 12.07 11.67 7 221022 88 42400218
Left ventricular dysfunction 12.06 11.67 26 221003 11475 42388831
Cardiac murmur 12.03 11.67 110 220919 12665 42387641
Oral pain 11.98 11.67 30 220999 12566 42387740
Chronic obstructive pulmonary disease 11.95 11.67 243 220786 62871 42337435
Cervical vertebral fracture 11.95 11.67 33 220996 2330 42397976
Anorectal discomfort 11.91 11.67 32 220997 2223 42398083
Osteoporosis 11.91 11.67 124 220905 14782 42385524
Angina unstable 11.90 11.67 26 221003 11422 42388884
Tenosynovitis stenosans 11.90 11.67 5 221024 29 42400277
Bronchial carcinoma 11.89 11.67 20 221009 1000 42399306
Irritable bowel syndrome 11.89 11.67 52 220977 4629 42395677
Spinal stenosis 11.85 11.67 65 220964 6341 42393965
Catatonia 11.84 11.67 9 221020 6230 42394076
Liver sarcoidosis 11.84 11.67 4 221025 11 42400295
Metastases to lung 11.83 11.67 26 221003 11398 42388908
Cutaneous lupus erythematosus 11.80 11.67 18 221011 828 42399478
Lymphadenitis bacterial 11.79 11.67 6 221023 57 42400249
Campylobacter infection 11.78 11.67 24 221005 1391 42398915
Premature baby 11.77 11.67 71 220958 23082 42377224
Osteochondrosis 11.74 11.67 24 221005 1394 42398912
Anastomotic fistula 11.74 11.67 7 221022 93 42400213
Arterial occlusive disease 11.72 11.67 50 220979 4403 42395903
Sinus headache 11.71 11.67 22 221007 1201 42399105
Internal fixation of fracture 11.67 11.67 7 221022 94 42400212

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Therapy interrupted 7636.51 11.15 4681 805874 45141 109733603
Drug ineffective 5391.91 11.15 23656 786899 1496884 108281860
Joint swelling 2910.15 11.15 8463 802092 434382 109344362
Synovitis 2893.38 11.15 6276 804279 267816 109510928
Drug intolerance 2808.68 11.15 7911 802644 398601 109380143
Therapeutic product effect decreased 2612.12 11.15 5624 804931 238692 109540052
Acute kidney injury 2558.20 11.15 744 809811 634686 109144058
Drug interaction 2526.78 11.15 339 810216 499844 109278900
Toxicity to various agents 2497.11 11.15 297 810258 480258 109298486
Treatment failure 2253.92 11.15 5733 804822 271501 109507243
Contraindicated product administered 2195.33 11.15 5302 805253 242965 109535779
Hypotension 2023.60 11.15 660 809895 523189 109255555
Febrile neutropenia 1992.39 11.15 75 810480 316692 109462052
Arthropathy 1895.51 11.15 5505 805050 282017 109496727
Arthralgia 1607.02 11.15 10484 800071 769148 109009596
Neutropenia 1590.23 11.15 394 810161 374226 109404518
Psoriasis 1516.89 11.15 3242 807313 136751 109641993
Systemic lupus erythematosus 1451.04 11.15 4630 805925 249708 109529036
Completed suicide 1396.30 11.15 98 810457 242283 109536461
Hand deformity 1283.94 11.15 4019 806536 214487 109564257
Musculoskeletal stiffness 1246.18 11.15 4692 805863 275130 109503614
Anaemia 1237.69 11.15 1311 809244 545775 109232969
Drug abuse 1206.30 11.15 18 810537 177393 109601351
Malignant neoplasm progression 1194.35 11.15 16 810539 174551 109604193
C-reactive protein abnormal 1186.20 11.15 2808 807747 126887 109651857
Swelling 1100.40 11.15 5290 805265 345751 109432993
Pemphigus 1089.51 11.15 3756 806799 210814 109567930
Therapeutic product effect incomplete 1076.33 11.15 3848 806707 219957 109558787
Infection 1075.23 11.15 5374 805181 356826 109421918
Glossodynia 1054.81 11.15 3802 806753 218202 109560542
Death 1039.68 11.15 2234 808321 696635 109082109
Anti-cyclic citrullinated peptide antibody positive 1035.59 11.15 3311 807244 178673 109600071
Hyponatraemia 1019.42 11.15 182 810373 217471 109561273
Alopecia 1013.69 11.15 5313 805242 359440 109419304
Somnolence 989.23 11.15 471 810084 296978 109481766
Thrombocytopenia 983.93 11.15 676 809879 348209 109430535
Pain 978.12 11.15 10991 799564 943964 108834780
Disease progression 965.15 11.15 294 810261 243740 109535004
Rheumatoid factor positive 950.84 11.15 2607 807948 129033 109649711
Red blood cell sedimentation rate increased 918.57 11.15 1874 808681 76428 109702316
Platelet count decreased 892.77 11.15 288 810267 230155 109548589
Wound 885.73 11.15 3735 806820 230702 109548042
Intentional overdose 870.20 11.15 21 810534 132480 109646264
Bradycardia 845.36 11.15 81 810474 155436 109623308
Dyspnoea 836.88 11.15 4732 805823 1102140 108676604
Inflammation 830.66 11.15 3205 807350 190033 109588711
Hepatic enzyme increased 822.04 11.15 4572 805983 316320 109462424
Pericarditis 817.68 11.15 3478 807077 215636 109563108
Hypersensitivity 804.51 11.15 5392 805163 398606 109380138
Abdominal discomfort 788.05 11.15 5263 805292 388595 109390149
Cardiac arrest 758.38 11.15 248 810307 196505 109582239
Mobility decreased 748.43 11.15 3585 806970 233837 109544907
Intestinal stenosis 739.64 11.15 450 810105 4265 109774479
Drug hypersensitivity 736.77 11.15 5770 804785 448320 109330424
Helicobacter infection 713.68 11.15 2932 807623 178945 109599799
Red blood cell sedimentation rate abnormal 706.21 11.15 885 809670 23624 109755120
Pancytopenia 698.14 11.15 331 810224 209282 109569462
Electrocardiogram QT prolonged 697.97 11.15 22 810533 108938 109669806
White blood cell count decreased 675.56 11.15 423 810132 228967 109549777
Impaired healing 674.83 11.15 3045 807510 193672 109585072
Rheumatoid arthritis 674.46 11.15 4126 806429 295487 109483257
Neutrophil count decreased 670.70 11.15 58 810497 120883 109657861
Arthritis 665.71 11.15 2712 807843 164874 109613870
C-reactive protein increased 661.25 11.15 3255 807300 214664 109564080
Duodenal ulcer perforation 657.67 11.15 2814 807741 174886 109603858
Hyperkalaemia 656.90 11.15 104 810451 135692 109643052
Folliculitis 650.89 11.15 2694 807861 164959 109613785
Osteoarthritis 649.15 11.15 2857 807698 179766 109598978
Injection site pain 642.73 11.15 2797 807758 175125 109603619
Hypoxia 638.36 11.15 94 810461 129421 109649323
Oxygen saturation decreased 637.26 11.15 180 810375 156802 109621942
Constipation 620.21 11.15 1042 809513 356744 109422000
Psoriatic arthropathy 589.09 11.15 2928 807627 193833 109584911
Nasopharyngitis 587.27 11.15 4915 805640 389446 109389298
Dehydration 572.67 11.15 724 809831 278787 109499957
Depressed level of consciousness 571.03 11.15 74 810481 112204 109666540
Irritable bowel syndrome 570.71 11.15 2552 808003 161663 109617081
Lactic acidosis 569.64 11.15 26 810529 92785 109685959
Rhabdomyolysis 560.75 11.15 102 810453 120299 109658445
Ileal stenosis 559.42 11.15 330 810225 2940 109775804
Respiratory failure 559.36 11.15 454 810101 214878 109563866
Bone erosion 557.06 11.15 1121 809434 45250 109733494
Overdose 535.98 11.15 553 810002 233241 109545503
Metabolic acidosis 534.05 11.15 55 810500 99689 109679055
Myelosuppression 532.07 11.15 42 810513 94298 109684446
Atrial fibrillation 530.05 11.15 540 810015 229102 109549642
Hypokalaemia 529.52 11.15 342 810213 182106 109596638
Agitation 528.17 11.15 95 810460 112956 109665788
Coma 527.55 11.15 110 810445 117759 109660985
Peripheral swelling 522.21 11.15 4882 805673 399152 109379592
Drug reaction with eosinophilia and systemic symptoms 520.75 11.15 18 810537 82077 109696667
Discomfort 511.82 11.15 3002 807553 211705 109567039
Illness 508.62 11.15 1540 809015 80631 109698113
Fibromyalgia 502.83 11.15 2531 808024 168378 109610366
Cardio-respiratory arrest 502.45 11.15 116 810439 115720 109663024
Lupus-like syndrome 500.63 11.15 995 809560 39797 109738947
Muscle injury 494.33 11.15 2195 808360 138612 109640132
Multiple organ dysfunction syndrome 490.80 11.15 249 810306 151461 109627283
Loss of personal independence in daily activities 489.74 11.15 2289 808266 147731 109631013
Hypoglycaemia 488.46 11.15 124 810431 115980 109662764
Cytokine release syndrome 487.29 11.15 5 810550 70301 109708443
Tachycardia 483.29 11.15 569 809986 226076 109552668
Seizure 482.76 11.15 545 810010 220640 109558104
International normalised ratio increased 480.07 11.15 42 810513 86730 109692014
Hallucination 476.55 11.15 84 810471 101348 109677396
Renal impairment 476.25 11.15 408 810147 188037 109590707
Sinusitis 463.59 11.15 3739 806816 292949 109485795
Anal fistula 462.30 11.15 429 810126 8044 109770700
Sedation 461.56 11.15 10 810545 69673 109709071
Joint range of motion decreased 458.11 11.15 1939 808616 119893 109658851
Gastrointestinal disorder 450.54 11.15 3178 807377 238774 109539970
Tremor 448.26 11.15 492 810063 201740 109577004
Gastrointestinal haemorrhage 446.25 11.15 336 810219 165182 109613562
Drug specific antibody present 440.91 11.15 417 810138 8017 109770727
Blood creatinine increased 437.07 11.15 417 810138 182472 109596272
Fall 428.42 11.15 2629 807926 600853 109177891
Large intestinal stenosis 428.17 11.15 294 810261 3486 109775258
Intentional dose omission 426.15 11.15 625 809930 19455 109759289
Ankylosing spondylitis 421.77 11.15 546 810009 15066 109763678
Maternal exposure during pregnancy 420.55 11.15 3253 807302 251630 109527114
Rash 415.02 11.15 8376 802179 812588 108966156
Serotonin syndrome 410.93 11.15 4 810551 59149 109719595
Neuropathy peripheral 407.52 11.15 427 810128 178850 109599894
Rheumatic fever 406.43 11.15 1879 808676 120700 109658044
Suicide attempt 404.21 11.15 127 810428 103267 109675477
Sleep disorder due to general medical condition, insomnia type 402.34 11.15 1688 808867 103955 109674789
Knee arthroplasty 400.78 11.15 1216 809339 63732 109715012
Encephalopathy 399.00 11.15 59 810496 80996 109697748
Therapy cessation 391.30 11.15 954 809601 43903 109734841
Blood pressure decreased 388.89 11.15 178 810377 114913 109663831
Hyperglycaemia 387.88 11.15 76 810479 85014 109693730
Blood pressure increased 387.26 11.15 821 809734 257552 109521192
Bursitis 380.67 11.15 1922 808633 127996 109650748
Ill-defined disorder 376.84 11.15 2198 808357 154655 109624089
Renal failure 373.20 11.15 681 809874 225893 109552851
Neoplasm progression 369.23 11.15 27 810528 64568 109714176
Chest discomfort 368.91 11.15 438 810117 173410 109605334
Cardiac failure 364.75 11.15 505 810050 187121 109591623
Agranulocytosis 364.25 11.15 22 810533 61738 109717006
Injection site haemorrhage 360.93 11.15 768 809787 32260 109746484
Orthostatic hypotension 358.64 11.15 35 810520 66214 109712530
Musculoskeletal pain 358.33 11.15 2434 808121 180589 109598155
Syncope 358.02 11.15 582 809973 201954 109576790
Blister 354.74 11.15 2865 807690 224511 109554233
Infusion related reaction 350.34 11.15 4302 806253 376860 109401884
Pneumonia aspiration 345.09 11.15 85 810470 81148 109697596
Heart rate increased 344.76 11.15 327 810228 143507 109635237
Mental status changes 342.78 11.15 70 810485 76052 109702692
Grip strength decreased 340.29 11.15 1325 809230 78849 109699895
Uveitis 330.67 11.15 581 809974 21129 109757615
Type 2 diabetes mellitus 330.42 11.15 2329 808226 174903 109603841
Joint stiffness 326.91 11.15 1161 809394 66082 109712662
Cognitive disorder 323.80 11.15 118 810437 87393 109691351
Multiple sclerosis relapse 322.25 11.15 10 810545 50230 109728514
Swollen joint count increased 321.85 11.15 1341 809214 82320 109696424
Mucosal inflammation 316.65 11.15 154 810401 95987 109682757
Sepsis 315.81 11.15 1280 809275 326066 109452678
Respiratory arrest 315.07 11.15 31 810524 58268 109720476
Blood cholesterol increased 314.53 11.15 2376 808179 182409 109596335
Pyoderma gangrenosum 313.84 11.15 285 810270 5191 109773553
Adverse drug reaction 313.70 11.15 1568 808987 103991 109674753
Cough 311.47 11.15 2042 808513 459599 109319145
Vomiting 309.79 11.15 4754 805801 905921 108872823
Hidradenitis 309.50 11.15 276 810279 4904 109773840
Surgery 309.28 11.15 829 809726 40454 109738290
Injection site reaction 306.87 11.15 1381 809174 87689 109691055
Unresponsive to stimuli 305.88 11.15 50 810505 63740 109715004
Diarrhoea 301.88 11.15 6219 804336 1133286 108645458
Toxic epidermal necrolysis 301.81 11.15 32 810523 56695 109722049
Cardiac failure congestive 299.97 11.15 400 810155 150600 109628144
Gait inability 299.48 11.15 1867 808688 134509 109644235
Frequent bowel movements 297.43 11.15 1173 809382 70217 109708527
Blood bilirubin increased 293.97 11.15 95 810460 75877 109702867
Gastrointestinal inflammation 293.88 11.15 355 810200 9114 109769630
Dysphagia 292.98 11.15 419 810136 153181 109625563
Flushing 290.86 11.15 206 810349 104530 109674214
Product dose omission issue 290.83 11.15 1290 809265 320492 109458252
Hip arthroplasty 285.46 11.15 980 809575 54833 109723911
Enthesopathy 283.23 11.15 401 810154 12077 109766667
Hypomagnesaemia 281.38 11.15 51 810504 60319 109718425
Palmar-plantar erythrodysaesthesia syndrome 279.46 11.15 4 810551 41021 109737723
Facet joint syndrome 278.37 11.15 1425 809130 95403 109683341
Disseminated tuberculosis 273.92 11.15 257 810298 4889 109773855
Balance disorder 272.37 11.15 271 810284 116289 109662455
Stomatitis 270.12 11.15 3100 807455 267142 109511602
Pustular psoriasis 269.44 11.15 410 810145 13195 109765549
Demyelination 269.27 11.15 339 810216 9090 109769654
Rheumatoid nodule 268.44 11.15 511 810044 19785 109758959
Heart rate decreased 267.35 11.15 136 810419 82620 109696124
Intestinal obstruction 267.35 11.15 929 809626 52298 109726446
Angioedema 266.68 11.15 199 810356 98301 109680443
Tuberculosis 264.69 11.15 471 810084 17303 109761441
Tuberculin test positive 263.08 11.15 217 810338 3451 109775293
Hypervolaemia 262.88 11.15 28 810527 49432 109729312
Melaena 262.48 11.15 88 810467 68669 109710075
Neurotoxicity 261.71 11.15 11 810544 42196 109736548
Injection site papule 260.16 11.15 135 810420 909 109777835
Dyspnoea exertional 258.36 11.15 229 810326 103831 109674913
Pulmonary oedema 256.62 11.15 216 810339 100443 109678301
Fistula 256.14 11.15 427 810128 14872 109763872
Off label use 255.91 11.15 8724 801831 1491461 108287283
Plasma cell myeloma 255.65 11.15 72 810483 62864 109715880
Full blood count abnormal 255.60 11.15 50 810505 56002 109722742
Cardiogenic shock 255.54 11.15 54 810501 57284 109721460
Lip dry 253.76 11.15 1423 809132 98660 109680084
Obstructive airways disorder 253.48 11.15 23 810532 46126 109732618
Abdominal adhesions 251.83 11.15 224 810331 3966 109774778
Dysarthria 250.45 11.15 153 810402 83968 109694776
Dizziness 249.83 11.15 3608 806947 694585 109084159
Pain in extremity 247.78 11.15 4977 805578 482141 109296603
Cholestasis 247.30 11.15 82 810473 64436 109714308
Blood glucose increased 246.25 11.15 368 810187 132128 109646616
Acute respiratory failure 245.65 11.15 122 810433 75138 109703606
Paradoxical psoriasis 245.26 11.15 105 810450 424 109778320
Drug specific antibody 245.08 11.15 187 810368 2641 109776103
Lethargy 244.51 11.15 196 810359 93380 109685364
Disability 243.86 11.15 624 809931 29599 109749145
Drug level increased 243.70 11.15 31 810524 47688 109731056
Hepatic cytolysis 243.00 11.15 53 810502 55000 109723744
Injection site erythema 240.09 11.15 1341 809214 92835 109685909
Blood creatine phosphokinase increased 239.22 11.15 118 810437 72959 109705785
Disorientation 237.64 11.15 110 810445 70561 109708183
Blood pressure systolic increased 236.07 11.15 159 810396 82832 109695912
Respiratory distress 233.47 11.15 106 810449 68768 109709976
Haemoglobin decreased 232.70 11.15 984 809571 247743 109531001
Ileostomy 231.48 11.15 169 810386 2223 109776521
Aggression 230.93 11.15 73 810482 59137 109719607
Pleural effusion 229.30 11.15 611 809944 177098 109601646
Septic shock 228.95 11.15 509 810046 157019 109621725
Hepatic failure 228.05 11.15 109 810446 68630 109710114
Tenosynovitis 227.86 11.15 420 810135 15863 109762881
Asthenia 225.11 11.15 3623 806932 685376 109093368
Nausea 224.57 11.15 7126 803429 1228564 108550180
Product use issue 221.85 11.15 3361 807194 308334 109470410
Abscess intestinal 221.52 11.15 188 810367 3116 109775628
Foot deformity 219.52 11.15 818 809737 47662 109731082
Sacroiliitis 219.01 11.15 224 810331 4754 109773990
Ventricular tachycardia 219.00 11.15 49 810506 49960 109728784
Restlessness 218.28 11.15 70 810485 56189 109722555
Altered state of consciousness 217.81 11.15 75 810480 57551 109721193
Hallucination, visual 216.82 11.15 20 810535 39585 109739159
Impaired work ability 215.80 11.15 548 810007 25871 109752873
Bone marrow failure 215.71 11.15 77 810478 57771 109720973
Leukopenia 211.98 11.15 486 810069 148305 109630439
Tumour lysis syndrome 209.82 11.15 3 810552 30798 109747946
Shock 209.12 11.15 66 810489 53522 109725222
Lymphocyte count decreased 208.72 11.15 79 810476 57164 109721580
Intentional product misuse 208.64 11.15 411 810144 132493 109646251
Finger deformity 207.35 11.15 623 809932 32469 109746275
Pulmonary embolism 206.52 11.15 839 809716 213635 109565109
Upper gastrointestinal haemorrhage 205.93 11.15 56 810499 50040 109728704
Adverse event 205.13 11.15 1434 809121 107375 109671369
Lower respiratory tract infection 204.09 11.15 2699 807856 240407 109538337
Wound infection 201.45 11.15 1304 809251 95161 109683583
Drug withdrawal syndrome 201.08 11.15 22 810533 38032 109740712
Urinary retention 200.22 11.15 132 810423 69551 109709193
Inflammatory bowel disease 200.12 11.15 256 810299 6978 109771766
Inappropriate antidiuretic hormone secretion 199.80 11.15 12 810543 33839 109744905
Panniculitis 199.55 11.15 387 810168 15195 109763549
Sciatica 199.10 11.15 1259 809296 91140 109687604
Small intestinal obstruction 197.65 11.15 602 809953 31611 109747133
Pulmonary arterial hypertension 197.01 11.15 10 810545 32558 109746186
Injury 196.08 11.15 2075 808480 175190 109603554
Joint effusion 195.69 11.15 457 810098 20448 109758296
Stevens-Johnson syndrome 195.50 11.15 51 810504 46850 109731894
Subdural haematoma 195.38 11.15 20 810535 36434 109742310
Small intestinal stenosis 194.95 11.15 121 810434 1192 109777552
Herpes zoster 193.67 11.15 1410 809145 106969 109671775
Polyarthritis 193.55 11.15 429 810126 18534 109760210
Respiratory depression 193.03 11.15 10 810545 31991 109746753
Generalised tonic-clonic seizure 191.93 11.15 80 810475 54600 109724144
Intestinal resection 191.66 11.15 187 810368 3742 109775002
Psychotic disorder 191.30 11.15 67 810488 50870 109727874
Hypoaesthesia 189.91 11.15 3298 807257 310925 109467819
Intestinal fistula 189.73 11.15 132 810423 1601 109777143
Faecal calprotectin increased 189.38 11.15 240 810315 6479 109772265
Device expulsion 188.42 11.15 9 810546 30882 109747862
Abscess 187.31 11.15 533 810022 26936 109751808
Nail disorder 186.75 11.15 881 809674 57054 109721690
Dyskinesia 185.91 11.15 72 810483 51374 109727370
Coeliac disease 185.07 11.15 716 809839 42471 109736273
Live birth 182.84 11.15 998 809557 68486 109710258
Arrhythmia 182.68 11.15 145 810410 69430 109709314
Tachypnoea 182.05 11.15 34 810521 39361 109739383
Acute hepatic failure 180.74 11.15 26 810529 36442 109742302
Pulmonary fibrosis 179.72 11.15 1323 809232 100719 109678025
Gastrointestinal wall thickening 179.66 11.15 174 810381 3449 109775295
Pulmonary hypertension 177.99 11.15 91 810464 55129 109723615
Rash maculo-papular 177.52 11.15 169 810386 74053 109704691
Blood parathyroid hormone decreased 177.38 11.15 333 810222 12756 109765988
Myoclonus 177.12 11.15 18 810537 32980 109745764
Night sweats 176.22 11.15 1626 808929 132357 109646387
Disturbance in attention 176.02 11.15 119 810436 61876 109716868
Granuloma skin 175.79 11.15 305 810250 10978 109767766
Breast cancer stage III 175.43 11.15 1086 809469 78031 109700713
Diabetic ketoacidosis 174.80 11.15 46 810509 42012 109736732
Labelled drug-drug interaction medication error 174.12 11.15 10 810545 29292 109749452
Musculoskeletal disorder 173.68 11.15 459 810096 22205 109756539
Adverse reaction 173.17 11.15 544 810011 29050 109749694
Status epilepticus 172.68 11.15 16 810539 31555 109747189
Sinus bradycardia 172.36 11.15 11 810544 29472 109749272
Cerebral haemorrhage 172.34 11.15 134 810421 64834 109713910
Peripheral venous disease 170.72 11.15 1129 809426 82988 109695756
Jaundice 170.48 11.15 112 810443 59124 109719620
Haematemesis 169.78 11.15 112 810443 58996 109719748
Pancreatitis acute 168.07 11.15 118 810437 60156 109718588
Blood alkaline phosphatase increased 167.93 11.15 163 810392 70772 109707972
Haemoptysis 167.72 11.15 165 810390 71189 109707555
Abnormal behaviour 167.47 11.15 40 810515 38999 109739745
Thrombotic microangiopathy 167.12 11.15 12 810543 29137 109749607
Oedema peripheral 166.37 11.15 1572 808983 327088 109451656
Poisoning deliberate 166.19 11.15 6 810549 26325 109752419
Suicidal ideation 165.87 11.15 270 810285 93667 109685077
Haematoma 165.01 11.15 113 810442 58363 109720381
Liver injury 164.61 11.15 1757 808798 148656 109630088
Osteoporosis 164.51 11.15 1149 809406 86003 109692741
Ascites 163.64 11.15 267 810288 92541 109686203
Road traffic accident 163.43 11.15 1346 809209 106052 109672692
Acute myocardial infarction 163.24 11.15 225 810330 83552 109695192
Obesity 162.62 11.15 1402 809153 111949 109666795
Extrapyramidal disorder 162.34 11.15 13 810542 28854 109749890
Neutropenic sepsis 161.89 11.15 18 810537 30728 109748016
Colectomy 160.78 11.15 179 810376 4199 109774545
Intentional self-injury 159.29 11.15 39 810516 37390 109741354
Immunodeficiency 159.22 11.15 635 809920 38203 109740541
Disseminated intravascular coagulation 159.06 11.15 52 810503 41234 109737510
Hyperbilirubinaemia 158.88 11.15 19 810536 30652 109748092
Drug tolerance decreased 158.18 11.15 503 810052 27037 109751707
Epistaxis 157.96 11.15 462 810093 129910 109648834
Neck pain 157.76 11.15 1486 809069 121644 109657100
Blood pressure fluctuation 156.04 11.15 191 810364 74633 109704111
Poisoning 155.90 11.15 16 810539 29089 109749655
Circulatory collapse 155.64 11.15 60 810495 42933 109735811
Lower limb fracture 155.15 11.15 1015 809540 74333 109704411
Hepatocellular injury 155.13 11.15 89 810466 50553 109728191
Withdrawal syndrome 154.06 11.15 23 810532 31357 109747387
Anaphylactic shock 153.09 11.15 94 810461 51452 109727292
Acute respiratory distress syndrome 152.53 11.15 101 810454 53097 109725647
Nasal congestion 152.47 11.15 306 810249 97976 109680768
Loss of consciousness 151.87 11.15 831 809724 195475 109583269
Sinus tachycardia 151.54 11.15 68 810487 44425 109734319
Blood pressure diastolic decreased 151.53 11.15 38 810517 35847 109742897
Hypophosphataemia 148.38 11.15 31 810524 33151 109745593
Device issue 148.34 11.15 573 809982 33962 109744782
Productive cough 148.19 11.15 392 810163 113913 109664831
Myalgia 147.08 11.15 989 809566 221392 109557352
Hypercholesterolaemia 146.66 11.15 1154 809401 89683 109689061
Joint dislocation 146.63 11.15 567 809988 33623 109745121
Therapy non-responder 146.22 11.15 1780 808775 155527 109623217
Miosis 146.19 11.15 3 810552 21980 109756764
Ventricular fibrillation 145.71 11.15 60 810495 41253 109737491
Injection site pruritus 145.64 11.15 752 809803 50506 109728238
Intestinal anastomosis complication 145.11 11.15 67 810488 336 109778408
Joint destruction 144.08 11.15 275 810280 10668 109768076
Ear infection 144.08 11.15 869 809686 61863 109716881
Pneumonitis 143.70 11.15 211 810344 76320 109702424
Deep vein thrombosis postoperative 143.68 11.15 833 809722 58458 109720286
Dislocation of vertebra 143.21 11.15 668 809887 43053 109735691
Basal cell carcinoma 142.70 11.15 684 809871 44586 109734158
Osteonecrosis of jaw 142.00 11.15 88 810467 47929 109730815
Condition aggravated 141.91 11.15 6664 803891 728172 109050572
Blood urea increased 141.21 11.15 117 810438 54840 109723904
Eosinophilia 140.81 11.15 130 810425 57806 109720938
Urticaria 140.33 11.15 3191 807364 315666 109463078
Ejection fraction decreased 139.99 11.15 62 810493 40818 109737926
Torsade de pointes 139.75 11.15 6 810549 22594 109756150
Full blood count decreased 139.45 11.15 32 810523 32067 109746677
Hypocalcaemia 139.34 11.15 164 810391 65202 109713542
Palpitations 139.10 11.15 646 809909 158566 109620178
Hypothyroidism 138.83 11.15 199 810356 72700 109706044
Coagulopathy 138.60 11.15 63 810492 40848 109737896
Haemorrhage intracranial 138.23 11.15 23 810532 28946 109749798
Joint injury 136.89 11.15 619 809936 39375 109739369
Creatinine renal clearance decreased 134.21 11.15 6 810549 21809 109756935
Apparent death 133.91 11.15 134 810421 2768 109775976
Autoimmune disorder 133.54 11.15 880 809675 64603 109714141
X-ray abnormal 133.50 11.15 594 809961 37523 109741221
Liver function test increased 133.24 11.15 1107 809448 87441 109691303
Haemorrhage 132.98 11.15 373 810182 106319 109672425
Gamma-glutamyltransferase increased 132.66 11.15 152 810403 61157 109717587
Anal abscess 131.07 11.15 274 810281 11364 109767380
Dermatitis psoriasiform 130.42 11.15 147 810408 3497 109775247
Intestinal anastomosis 130.38 11.15 83 810472 858 109777886
No adverse event 129.64 11.15 213 810342 73626 109705118
Angina pectoris 128.86 11.15 160 810395 62135 109716609
Chills 128.82 11.15 842 809713 189738 109589006
Haematuria 128.28 11.15 259 810296 82746 109695998
Product administration error 128.14 11.15 56 810499 37161 109741583
Product use in unapproved indication 127.40 11.15 2410 808145 444967 109333777
Delusion 127.40 11.15 13 810542 23742 109755002
Exposure during pregnancy 127.10 11.15 1826 808729 165598 109613146
Intestinal fibrosis 126.24 11.15 55 810500 234 109778510
Surgical failure 125.99 11.15 81 810474 853 109777891
Anal stenosis 125.76 11.15 70 810485 552 109778192
Adjustment disorder with depressed mood 125.51 11.15 645 809910 43238 109735506
Urinary incontinence 125.38 11.15 103 810452 48484 109730260
Onychomadesis 124.29 11.15 662 809893 45001 109733743
Dystonia 124.22 11.15 20 810535 25785 109752959
Cytomegalovirus infection 123.29 11.15 130 810425 54314 109724430
Cytopenia 123.15 11.15 34 810521 30082 109748662
Pneumonia 123.12 11.15 5214 805341 871500 108907244
Hepatic encephalopathy 123.09 11.15 28 810527 28228 109750516
Aphasia 122.60 11.15 151 810404 58846 109719898
Lymphopenia 122.47 11.15 71 810484 40099 109738645
Electrolyte imbalance 122.39 11.15 59 810496 36969 109741775
Speech disorder 122.33 11.15 163 810392 61406 109717338
Hyperlipidaemia 121.76 11.15 55 810500 35793 109742951
Respiratory rate increased 121.74 11.15 19 810536 25064 109753680
Chronic obstructive pulmonary disease 121.49 11.15 402 810153 108756 109669988
Colitis ulcerative 121.15 11.15 976 809579 76387 109702357
Hypothermia 120.90 11.15 23 810532 26279 109752465
Bone pain 119.93 11.15 182 810373 64951 109713793
Prescribed overdose 119.78 11.15 1072 809483 86509 109692235
Posterior reversible encephalopathy syndrome 119.71 11.15 49 810506 33812 109744932
Graft versus host disease 119.69 11.15 4 810551 18802 109759942
Malignant melanoma 119.33 11.15 332 810223 16559 109762185
Onychomycosis 119.15 11.15 579 809976 37952 109740792
Chronic kidney disease 118.79 11.15 237 810318 76054 109702690
Right ventricular failure 118.65 11.15 23 810532 25931 109752813
Dry skin 118.07 11.15 399 810156 107254 109671490
Furuncle 118.05 11.15 221 810334 8447 109770297
Pallor 117.89 11.15 144 810411 56323 109722421
IgA nephropathy 116.99 11.15 130 810425 3043 109775701
Dysgeusia 116.36 11.15 209 810346 69776 109708968
Fear of injection 116.17 11.15 223 810332 8688 109770056
Cytomegalovirus viraemia 115.90 11.15 3 810552 17761 109760983
Arthrodesis 115.41 11.15 120 810435 2598 109776146
Irritability 115.34 11.15 108 810447 47701 109731043
Fistula discharge 115.18 11.15 96 810459 1550 109777194
Muscle rigidity 114.84 11.15 19 810536 24012 109754732
Nephropathy toxic 114.29 11.15 30 810525 27448 109751296
Bacteraemia 114.26 11.15 86 810469 42304 109736440
Antinuclear antibody positive 114.12 11.15 225 810330 8943 109769801
Dysphonia 113.88 11.15 241 810314 75688 109703056
Hallucination, auditory 113.32 11.15 27 810528 26370 109752374
Intestinal dilatation 112.80 11.15 136 810419 3484 109775260
Retinitis 111.88 11.15 502 810053 31825 109746919
Haemodynamic instability 111.85 11.15 17 810538 22871 109755873
Synovial cyst 111.53 11.15 254 810301 11176 109767568
Product label confusion 111.44 11.15 393 810162 22284 109756460
Drug eruption 111.18 11.15 724 809831 52935 109725809
Pericardial effusion 111.13 11.15 154 810401 57063 109721681
Deep vein thrombosis 111.04 11.15 587 809968 139300 109639444
Blood lactate dehydrogenase increased 110.71 11.15 97 810458 44237 109734507
Exostosis 109.63 11.15 643 809912 45313 109733431
Mydriasis 109.33 11.15 16 810539 22141 109756603
Haemodialysis 108.59 11.15 5 810550 17714 109761030
Blood potassium increased 108.34 11.15 54 810501 33195 109745549
Mycobacterium tuberculosis complex test positive 108.18 11.15 127 810428 3161 109775583
Renal tubular necrosis 107.90 11.15 44 810511 30431 109748313
Second primary malignancy 107.87 11.15 6 810549 18062 109760682
Parkinsonism 107.24 11.15 17 810538 22170 109756574
Iridocyclitis 107.13 11.15 163 810392 5245 109773499
Ileal ulcer 106.95 11.15 96 810459 1721 109777023
Salivary hypersecretion 106.49 11.15 5 810550 17416 109761328
Blood pressure systolic abnormal 105.54 11.15 26 810529 24824 109753920
Shock haemorrhagic 105.53 11.15 34 810521 27213 109751531
Anastomotic stenosis 105.52 11.15 65 810490 631 109778113
Shoulder arthroplasty 105.10 11.15 131 810424 3476 109775268
Coronary artery disease 104.66 11.15 231 810324 71459 109707285
Coordination abnormal 104.07 11.15 28 810527 25200 109753544
Blood pressure diastolic abnormal 103.98 11.15 30 810525 25785 109752959
Atrial flutter 103.79 11.15 25 810530 24237 109754507
Intestinal mucosal hypertrophy 103.38 11.15 56 810499 416 109778328
Cerebral infarction 102.22 11.15 138 810417 51700 109727044
Throat irritation 102.16 11.15 146 810409 53406 109725338
Decreased appetite 102.12 11.15 2680 807875 473166 109305578
Abdominal abscess 102.10 11.15 210 810345 8609 109770135
Rectal stenosis 101.52 11.15 54 810501 385 109778359
Cytomegalovirus infection reactivation 101.05 11.15 9 810546 18324 109760420
Palmoplantar pustulosis 100.75 11.15 72 810483 914 109777830
Troponin increased 100.58 11.15 46 810509 29720 109749024
Small intestinal resection 100.57 11.15 76 810479 1057 109777687
Blood sodium decreased 100.42 11.15 80 810475 38239 109740505
Hyperhidrosis 100.29 11.15 883 809672 186415 109592329
Nodule 99.94 11.15 489 810066 32142 109746602
Vision blurred 99.86 11.15 546 810009 128476 109650268
Presyncope 99.62 11.15 127 810428 48760 109729984
Leukocytosis 99.51 11.15 150 810405 53678 109725066
Acidosis 98.81 11.15 22 810533 22509 109756235
Progressive multifocal leukoencephalopathy 98.69 11.15 30 810525 24926 109753818
Dactylitis 98.54 11.15 136 810419 3997 109774747
Injection site urticaria 98.48 11.15 314 810241 16901 109761843
Cerebrovascular accident 98.24 11.15 852 809703 180432 109598312
Akathisia 98.24 11.15 7 810548 17106 109761638
Mania 98.15 11.15 17 810538 20779 109757965
Transplant rejection 98.12 11.15 29 810526 24538 109754206
Lung disorder 97.52 11.15 1858 808697 178189 109600555
Oral mucosal exfoliation 97.41 11.15 87 810468 1549 109777195
Bronchospasm 97.20 11.15 50 810505 30189 109748555
Deformity 97.17 11.15 224 810331 9936 109768808
Allergic oedema 96.35 11.15 69 810486 879 109777865
Schizophrenia 96.34 11.15 21 810534 21805 109756939
Hyperphosphataemia 96.09 11.15 6 810549 16375 109762369
Activated partial thromboplastin time prolonged 95.78 11.15 23 810532 22345 109756399
Therapeutic response decreased 95.40 11.15 1105 809450 95394 109683350
Premature delivery 95.02 11.15 53 810502 30579 109748165
Infusion site pain 94.81 11.15 9 810546 17410 109761334
Faecal calprotectin abnormal 94.65 11.15 48 810507 306 109778438
Rheumatoid lung 94.28 11.15 136 810419 4168 109774576
Post transplant lymphoproliferative disorder 93.79 11.15 5 810550 15608 109763136
Blood calcium decreased 93.72 11.15 75 810480 35770 109742974
Back injury 93.64 11.15 632 809923 46767 109731977
Skin ulcer 93.26 11.15 791 809764 62854 109715890
COVID-19 pneumonia 93.07 11.15 81 810474 37062 109741682
Intervertebral disc protrusion 92.79 11.15 426 810129 27272 109751472
Anhedonia 92.49 11.15 5 810550 15423 109763321
Accidental overdose 92.42 11.15 148 810407 51686 109727058
Ileocaecal resection 91.66 11.15 56 810499 535 109778209
Atrioventricular block complete 91.38 11.15 18 810537 20064 109758680
Acute generalised exanthematous pustulosis 91.36 11.15 23 810532 21641 109757103
Joint arthroplasty 91.34 11.15 121 810434 3416 109775328
Musculoskeletal deformity 91.31 11.15 82 810473 1471 109777273
Inflammatory marker increased 91.21 11.15 273 810282 14196 109764548
Anxiety 90.91 11.15 1883 808672 343195 109435549
Oliguria 90.85 11.15 14 810541 18643 109760101
Human antichimeric antibody positive 90.81 11.15 86 810469 1656 109777088
Injection site swelling 90.57 11.15 768 809787 61022 109717722
Sleep disorder 90.48 11.15 1998 808557 196646 109582098
Pulseless electrical activity 90.31 11.15 9 810546 16748 109761996
Pulmonary tuberculosis 90.18 11.15 204 810351 8935 109769809
Cyanosis 90.05 11.15 53 810502 29688 109749056
Hepatic function abnormal 89.92 11.15 343 810212 88952 109689792
Hypovolaemia 89.51 11.15 24 810531 21650 109757094
Joint laxity 89.50 11.15 101 810454 2406 109776338
Clostridium difficile colitis 88.92 11.15 114 810441 43664 109735080
Body temperature increased 88.64 11.15 166 810389 54547 109724197
Gastrointestinal mucosa hyperaemia 88.55 11.15 54 810501 514 109778230
Body height below normal 88.47 11.15 92 810463 1992 109776752
Transfusion 88.22 11.15 38 810517 25434 109753310
Cutaneous T-cell lymphoma 87.75 11.15 116 810439 3268 109775476
Lip swelling 87.24 11.15 148 810407 50519 109728225
Antibiotic therapy 87.17 11.15 68 810487 994 109777750
Foetal death 86.68 11.15 287 810268 15758 109762986
Mental impairment 86.36 11.15 29 810526 22610 109756134
Skin necrosis 86.00 11.15 349 810206 21163 109757581
Limb deformity 85.93 11.15 121 810434 3625 109775119
Toxic encephalopathy 85.14 11.15 7 810548 15207 109763537
Alanine aminotransferase increased 85 11.15 898 809657 182875 109595869
Neuralgia 84.95 11.15 140 810415 48338 109730406
Skin plaque 84.89 11.15 244 810311 12401 109766343
Lupus vulgaris 84.69 11.15 480 810075 33403 109745341
Chondropathy 84.36 11.15 105 810450 2782 109775962
Blepharospasm 84.26 11.15 689 809866 54162 109724582
C-reactive protein 84.10 11.15 442 810113 29889 109748855
Anti-cyclic citrullinated peptide antibody 83.91 11.15 329 810226 19635 109759109
Chromaturia 83.82 11.15 56 810499 29304 109749440
Aspartate aminotransferase increased 83.43 11.15 759 809796 159177 109619567
Liver disorder 83.33 11.15 1486 809069 140757 109637987
Transient ischaemic attack 83.24 11.15 219 810336 63763 109714981
Forced expiratory volume decreased 83.16 11.15 3 810552 13173 109765571
Dysuria 83.14 11.15 200 810355 60031 109718713
Alanine aminotransferase abnormal 82.98 11.15 200 810355 9134 109769610
End stage renal disease 82.80 11.15 27 810528 21446 109757298
Renal injury 82.61 11.15 18 810537 18695 109760049
Injection site bruising 82.59 11.15 651 809904 50612 109728132
Dermatitis allergic 82.56 11.15 347 810208 21377 109757367
Ataxia 82.55 11.15 60 810495 30048 109748696
Ulcer 82.27 11.15 570 809985 42546 109736198
Malaise 82.08 11.15 5847 804708 665972 109112772
Intestinal ulcer 81.95 11.15 95 810460 2332 109776412
Blood glucose decreased 81.85 11.15 58 810497 29430 109749314
Fine motor skill dysfunction 81.78 11.15 157 810398 6117 109772627
Blood pressure systolic decreased 81.71 11.15 4 810551 13437 109765307
Brain oedema 81.39 11.15 65 810490 31033 109747711
Cutaneous leishmaniasis 81.36 11.15 45 810510 350 109778394
Bronchopulmonary aspergillosis 81.24 11.15 60 810495 29803 109748941
Hepatic cirrhosis 81.11 11.15 805 809750 66821 109711923
Antinuclear antibody increased 81.08 11.15 68 810487 1108 109777636
Rhinorrhoea 80.81 11.15 432 810123 102234 109676510
Personality disorder 80.76 11.15 3 810552 12834 109765910
Gastrointestinal scarring 80.68 11.15 48 810507 435 109778309
Subarachnoid haemorrhage 80.39 11.15 60 810495 29642 109749102
Eosinophil count increased 80.28 11.15 27 810528 21031 109757713
COVID-19 80.12 11.15 2358 808197 242702 109536042
Pneumonia legionella 79.97 11.15 114 810441 3455 109775289
Product substitution issue 79.72 11.15 358 810197 22703 109756041
Body temperature decreased 79.44 11.15 92 810463 36843 109741901
Metastases to central nervous system 79.08 11.15 34 810521 22783 109755961
Foot operation 78.68 11.15 169 810386 7144 109771600
Pouchitis 78.67 11.15 72 810483 1325 109777419
Gastrointestinal fistula 78.66 11.15 62 810493 921 109777823
Dialysis 78.65 11.15 23 810532 19596 109759148
Histoplasmosis disseminated 77.91 11.15 118 810437 3781 109774963
Rales 77.91 11.15 42 810513 24697 109754047
Metastases to bone 77.90 11.15 69 810486 31303 109747441
Henoch-Schonlein purpura 77.84 11.15 114 810441 3543 109775201
Maternal exposure timing unspecified 77.81 11.15 333 810222 20680 109758064
Deafness transitory 77.01 11.15 64 810491 1029 109777715
Electrocardiogram abnormal 76.73 11.15 21 810534 18688 109760056
Urine output decreased 76.63 11.15 25 810530 19851 109758893
Cystitis haemorrhagic 76.30 11.15 3 810552 12206 109766538
Myopathy 76.26 11.15 44 810511 24916 109753828
Pharyngitis streptococcal 75.79 11.15 242 810313 13035 109765709
Accidental exposure to product 75.60 11.15 158 810397 49850 109728894
Gout 75.54 11.15 94 810461 36472 109742272
Ileostomy closure 75.48 11.15 42 810513 331 109778413
Lower gastrointestinal haemorrhage 75.35 11.15 21 810534 18465 109760279
Hepatitis acute 75.23 11.15 22 810533 18744 109760000
Lymphoma 74.96 11.15 320 810235 19851 109758893
Substance abuse 74.84 11.15 4 810551 12459 109766285
Confusional state 74.80 11.15 2745 807810 465935 109312809
Exposure to toxic agent 74.56 11.15 5 810550 12853 109765891
Aspergillus infection 74.30 11.15 48 810507 25568 109753176
Device related infection 74.14 11.15 109 810446 39410 109739334
Injection site warmth 74.11 11.15 288 810267 17117 109761627
Pseudopolyp 73.97 11.15 51 810504 609 109778135
Tardive dyskinesia 73.95 11.15 7 810548 13572 109765172
Psychomotor hyperactivity 73.89 11.15 28 810527 20249 109758495
Bronchitis chronic 73.67 11.15 131 810424 4809 109773935
Migraine 73.62 11.15 1712 808843 169940 109608804
Dementia 73.56 11.15 74 810481 31599 109747145
Diarrhoea haemorrhagic 73.41 11.15 267 810288 15372 109763372
Hepatitis cholestatic 73.40 11.15 19 810536 17547 109761197
Skin toxicity 73.29 11.15 3 810552 11780 109766964
Micturition urgency 73.26 11.15 25 810530 19295 109759449
Pulmonary alveolar haemorrhage 73.14 11.15 28 810527 20122 109758622
Haemolytic anaemia 72.78 11.15 31 810524 20889 109757855
Ileectomy 72.73 11.15 38 810517 260 109778484
Acute myeloid leukaemia 72.59 11.15 104 810451 38006 109740738
Pruritus allergic 72.53 11.15 75 810480 1613 109777131
Dyspepsia 72.13 11.15 1872 808683 189093 109589651
Acute graft versus host disease 71.88 11.15 6 810549 12875 109765869
Contrast media allergy 71.84 11.15 106 810449 3317 109775427
Emotional distress 71.83 11.15 137 810418 44710 109734034
Drug resistance 71.79 11.15 195 810360 56179 109722565
Immunosuppression 71.70 11.15 289 810266 17470 109761274
Endometriosis 71.26 11.15 120 810435 4214 109774530
Investigation abnormal 71.25 11.15 89 810466 2367 109776377
Red blood cell sedimentation rate 71.09 11.15 133 810422 5081 109773663
Hyperthyroidism 70.70 11.15 66 810489 29195 109749549
Vascular device infection 70.66 11.15 17 810538 16495 109762249
Paranoia 70.43 11.15 38 810517 22336 109756408
Injection site rash 70.33 11.15 349 810206 23070 109755674
Heart rate irregular 69.87 11.15 89 810466 34185 109744559
Gastrointestinal stenosis 69.71 11.15 41 810514 363 109778381
Fistula of small intestine 69.69 11.15 60 810495 1015 109777729
Axial spondyloarthritis 69.44 11.15 55 810500 823 109777921
Terminal ileitis 69.10 11.15 73 810482 1611 109777133
Pneumonia bacterial 68.59 11.15 55 810500 26206 109752538
Kidney transplant rejection 68.53 11.15 5 810550 11982 109766762
Muscle twitching 68.31 11.15 71 810484 29864 109748880
Spinal instability 68.08 11.15 43 810512 438 109778306
Sarcoidosis 67.95 11.15 225 810330 12354 109766390
Hypernatraemia 67.75 11.15 23 810532 17810 109760934
Heparin-induced thrombocytopenia 67.57 11.15 4 810551 11420 109767324
Hot flush 67.57 11.15 252 810303 65784 109712960
Guttate psoriasis 67.53 11.15 45 810510 506 109778238
Rhinitis allergic 66.57 11.15 24 810531 17898 109760846
Diabetes mellitus inadequate control 66.41 11.15 72 810483 29703 109749041
Blood lactic acid increased 66.32 11.15 17 810538 15804 109762940
Loose body in joint 66.32 11.15 66 810489 1354 109777390
Atlantoaxial instability 66.28 11.15 36 810519 269 109778475
Pyrexia 66.19 11.15 5676 804879 892589 108886155
Erythema multiforme 66.17 11.15 36 810519 21061 109757683
Contusion 66.13 11.15 2207 808348 231154 109547590
Infusion site extravasation 66.09 11.15 5 810550 11629 109767115
Prothrombin time prolonged 66.04 11.15 22 810533 17239 109761505
Cardiac failure acute 65.99 11.15 48 810507 24030 109754714
Respiratory acidosis 65.92 11.15 11 810544 13815 109764929
Aspiration 65.73 11.15 76 810479 30457 109748287
Pollakiuria 65.67 11.15 141 810414 44054 109734690
Eosinophilic granulomatosis with polyangiitis 65.54 11.15 3 810552 10683 109768061
Ischaemic stroke 65.26 11.15 127 810428 41136 109737608
Epicondylitis 65.23 11.15 87 810468 2473 109776271
Haemolysis 65.19 11.15 17 810538 15622 109763122
Sudden death 65.10 11.15 50 810505 24345 109754399
Head injury 64.96 11.15 136 810419 42881 109735863
Gastric disorder 64.83 11.15 443 810112 32914 109745830
Face oedema 64.08 11.15 91 810464 33378 109745366
Bradyphrenia 63.99 11.15 6 810549 11722 109767022
Enterocutaneous fistula 63.93 11.15 82 810473 2241 109776503
Pathogen resistance 63.41 11.15 25 810530 17647 109761097
Hyperammonaemia 63.13 11.15 12 810543 13720 109765024
Intestinal sepsis 62.99 11.15 55 810500 949 109777795
Prescribed underdose 62.94 11.15 743 809812 64431 109714313
Double stranded DNA antibody positive 62.68 11.15 43 810512 509 109778235
Granuloma 62.63 11.15 182 810373 9308 109769436
Hypoalbuminaemia 62.50 11.15 72 810483 28902 109749842
Aplastic anaemia 62.14 11.15 52 810503 24256 109754488
Atrioventricular block 62.01 11.15 23 810532 16854 109761890
Eye pruritus 61.88 11.15 90 810465 32685 109746059
Depressed mood 61.60 11.15 233 810322 60576 109718168
Hospice care 61.56 11.15 9 810546 12464 109766280
Gastrointestinal obstruction 61.54 11.15 79 810476 2161 109776583
Chest pain 61.47 11.15 2198 808357 374177 109404567
Inflammatory pain 61.38 11.15 66 810489 1487 109777257
Iritis 61.36 11.15 117 810438 4535 109774209
Pregnancy 61.29 11.15 608 809947 50459 109728285
Seronegative arthritis 61.04 11.15 224 810331 12953 109765791
Nocturia 61.02 11.15 24 810531 16966 109761778
Intentional product use issue 60.97 11.15 2307 808248 245599 109533145
Granulocytopenia 60.88 11.15 10 810545 12705 109766039
Bloody discharge 60.80 11.15 87 810468 2646 109776098
Dizziness postural 60.67 11.15 16 810539 14593 109764151
Hypovolaemic shock 60.50 11.15 16 810539 14567 109764177
Lymph node tuberculosis 60.43 11.15 56 810499 1048 109777696
Atrioventricular block first degree 60.18 11.15 15 810540 14210 109764534
Oesophagitis 60.18 11.15 73 810482 28642 109750102
Hypercapnia 60.12 11.15 6 810549 11153 109767591
Device dislocation 59.91 11.15 87 810468 31617 109747127
Spondylitis 59.64 11.15 201 810354 11137 109767607
Physical disability 59.60 11.15 122 810433 4984 109773760
Gastrointestinal stoma complication 59.39 11.15 95 810460 3194 109775550
Myocarditis 59.27 11.15 80 810475 29975 109748769
Blood calcium increased 59.23 11.15 29 810526 18011 109760733
Mucormycosis 59.17 11.15 5 810550 10623 109768121
Supraventricular tachycardia 59.11 11.15 55 810500 24367 109754377
Respiratory symptom 59.04 11.15 18 810537 14927 109763817
Polyuria 59.02 11.15 28 810527 17710 109761034
Stress cardiomyopathy 58.99 11.15 21 810534 15785 109762959
Hyperthermia 58.83 11.15 42 810513 21230 109757514
Myasthenia gravis 58.80 11.15 43 810512 21468 109757276
Toxic skin eruption 58.68 11.15 69 810486 27446 109751298
Erythema nodosum 58.55 11.15 142 810413 6511 109772233
Product administration interrupted 58.48 11.15 7 810548 11285 109767459
Ketoacidosis 58.27 11.15 4 810551 10083 109768661
Metastases to lung 58.14 11.15 50 810505 23013 109755731
Rectal discharge 58.08 11.15 54 810501 1015 109777729
Acute pulmonary oedema 57.84 11.15 26 810529 16970 109761774
Spondyloarthropathy 57.58 11.15 65 810490 1549 109777195
Anuria 57.53 11.15 56 810499 24285 109754459
Laryngitis 57.40 11.15 518 810037 41893 109736851
Gangrene 57.20 11.15 24 810531 16317 109762427
Blood potassium decreased 57.01 11.15 204 810351 53910 109724834
Injection site hypersensitivity 56.95 11.15 80 810475 2391 109776353
Myocardial ischaemia 56.81 11.15 67 810488 26617 109752127
Affect lability 56.73 11.15 33 810522 18604 109760140
Stenosis 56.73 11.15 94 810461 3257 109775487
Tendonitis 56.53 11.15 356 810199 25727 109753017
Hypogammaglobulinaemia 56.37 11.15 39 810516 20037 109758707
Pulmonary haemorrhage 56.28 11.15 25 810530 16431 109762313
Mineral metabolism disorder 56.24 11.15 36 810519 376 109778368
Drug tolerance 56.23 11.15 256 810299 16329 109762415
Blood loss anaemia 56.18 11.15 31 810524 17994 109760750
Angina unstable 56.14 11.15 25 810530 16407 109762337
Catatonia 56.13 11.15 8 810547 11292 109767452
Blood iron abnormal 56.11 11.15 62 810493 1442 109777302
Coma scale abnormal 55.77 11.15 4 810551 9722 109769022
Blood phosphorus increased 55.60 11.15 25 810530 16315 109762429
Treatment noncompliance 55.31 11.15 311 810244 72679 109706065
Bradykinesia 55.10 11.15 7 810548 10781 109767963
Lyme disease 55.03 11.15 107 810448 4209 109774535
Colonic fistula 54.90 11.15 45 810510 709 109778035
Dermatitis bullous 54.85 11.15 30 810525 17499 109761245
General physical health deterioration 54.73 11.15 3718 806837 421577 109357167
Tonsillitis 54.67 11.15 158 810397 8055 109770689
Rheumatic disorder 54.55 11.15 96 810459 3495 109775249
International normalised ratio fluctuation 54.29 11.15 103 810452 3977 109774767
Feeling cold 54.28 11.15 104 810451 33883 109744861
Limb operation 54.06 11.15 102 810453 3922 109774822
Increased appetite 54.05 11.15 21 810534 14956 109763788
Pulse absent 53.80 11.15 9 810546 11283 109767461
Latent tuberculosis 53.67 11.15 101 810454 3876 109774868
Systemic infection 53.64 11.15 5 810550 9814 109768930
BK virus infection 53.21 11.15 15 810540 13091 109765653
Pseudomonas infection 53.06 11.15 76 810479 27777 109750967
Hepatosplenic T-cell lymphoma 53.04 11.15 50 810505 957 109777787
Meniscus injury 52.92 11.15 151 810404 7642 109771102
Enterococcal infection 52.76 11.15 43 810512 20323 109758421
Blood uric acid increased 52.68 11.15 48 810507 21481 109757263
Diverticulitis 52.50 11.15 612 809943 52910 109725834
C-reactive protein decreased 52.50 11.15 84 810471 2825 109775919
Chronic recurrent multifocal osteomyelitis 52.11 11.15 21 810534 70 109778674
Spinal operation 52.08 11.15 188 810367 10784 109767960
Aplasia pure red cell 51.99 11.15 5 810550 9573 109769171
Apathy 51.97 11.15 27 810528 16212 109762532
Sneezing 51.84 11.15 97 810458 31887 109746857
Metastases to liver 51.66 11.15 114 810441 35272 109743472
Rectal abscess 51.63 11.15 80 810475 2616 109776128
Drug level above therapeutic 51.45 11.15 11 810544 11577 109767167
Ventricular extrasystoles 51.33 11.15 54 810501 22587 109756157
Concomitant disease aggravated 51.21 11.15 28 810527 16336 109762408
Product preparation error 51.11 11.15 9 810546 10870 109767874
Abdominal lymphadenopathy 51.05 11.15 65 810490 1763 109776981
Anticipatory anxiety 50.74 11.15 54 810501 1202 109777542
Hemiparesis 50.71 11.15 159 810396 43744 109735000
Faeces discoloured 50.70 11.15 108 810447 33840 109744904
Ovarian neoplasm 50.64 11.15 40 810515 596 109778148
Blood culture positive 50.59 11.15 4 810551 8972 109769772
Adjustment disorder 50.56 11.15 9 810546 10786 109767958
Eating disorder 50.53 11.15 93 810462 30765 109747979
Product monitoring error 50.25 11.15 4 810551 8923 109769821
Enterocolonic fistula 49.60 11.15 25 810530 157 109778587
Bacterial infection 49.54 11.15 172 810383 45864 109732880
Procedural intestinal perforation 49.46 11.15 28 810527 229 109778515
Abnormal dreams 49.40 11.15 16 810539 12764 109765980
Sickle cell anaemia with crisis 49.23 11.15 6 810549 9539 109769205
Petechiae 49.16 11.15 59 810496 23258 109755486
Lymphadenopathy 49.12 11.15 698 809857 63137 109715607
Joint ankylosis 49.09 11.15 75 810480 2422 109776322
Infusion site swelling 49.04 11.15 7 810548 9870 109768874
Brain natriuretic peptide increased 49.04 11.15 11 810544 11198 109767546
Ageusia 49.03 11.15 43 810512 19602 109759142
B-cell lymphoma 48.95 11.15 139 810416 7015 109771729
Cartilage atrophy 48.71 11.15 25 810530 164 109778580
Jaundice cholestatic 48.70 11.15 23 810532 14585 109764159
Amyotrophic lateral sclerosis 48.65 11.15 68 810487 2023 109776721
Hallucinations, mixed 48.64 11.15 4 810551 8689 109770055
Glomerular filtration rate decreased 48.55 11.15 86 810469 28870 109749874
Glycosylated haemoglobin increased 48.49 11.15 61 810494 23558 109755186
Ileus paralytic 48.46 11.15 13 810542 11724 109767020
Blood thyroid stimulating hormone increased 48.26 11.15 15 810540 12286 109766458
Ventricular arrhythmia 48.15 11.15 8 810547 10079 109768665
Azotaemia 48.13 11.15 8 810547 10077 109768667
Transaminases increased 48.08 11.15 270 810285 63120 109715624
Ankle operation 48.06 11.15 55 810500 1331 109777413
Food intolerance 48.00 11.15 104 810451 4423 109774321
Polyneuropathy 47.67 11.15 102 810453 31910 109746834
Pulmonary congestion 47.52 11.15 97 810458 30869 109747875
Muscle spasticity 47.43 11.15 122 810433 35793 109742951
Dermatitis atopic 47.37 11.15 71 810484 25470 109753274
Cardiomyopathy 47.32 11.15 110 810445 33415 109745329
Gastrointestinal oedema 47.32 11.15 86 810469 3212 109775532
Tonsillar ulcer 47.22 11.15 34 810521 437 109778307
Proctitis 47.15 11.15 247 810308 16680 109762064
Blood pressure diastolic increased 47.14 11.15 41 810514 18766 109759978
Blood creatine increased 47.12 11.15 13 810542 11508 109767236
Pneumocystis jirovecii pneumonia 47.12 11.15 158 810397 42577 109736167
Sleep apnoea syndrome 47.06 11.15 146 810409 40301 109738443
DNA antibody positive 47.06 11.15 30 810525 311 109778433
Hypoxic-ischaemic encephalopathy 47.03 11.15 5 810550 8842 109769902
Antibody test positive 46.87 11.15 83 810472 3037 109775707
Cervical dysplasia 46.57 11.15 77 810478 2663 109776081
Nervousness 46.53 11.15 128 810427 36723 109742021
Hiccups 46.51 11.15 18 810537 12851 109765893
Fluid retention 46.41 11.15 454 810101 93853 109684891
Localised infection 45.74 11.15 500 810055 42548 109736196
Thirst 45.69 11.15 55 810500 21652 109757092
Hemiplegia 45.57 11.15 60 810495 22722 109756022
Large intestinal ulcer 45.49 11.15 118 810437 5643 109773101
Post procedural complication 45.42 11.15 343 810212 26315 109752429
Complication associated with device 45.37 11.15 48 810507 20025 109758719
Arthritis enteropathic 45.26 11.15 32 810523 399 109778345
Subileus 44.96 11.15 126 810429 6311 109772433
Wheelchair user 44.82 11.15 143 810412 7699 109771045
Knee operation 44.74 11.15 133 810422 6889 109771855
Cardiac disorder 44.72 11.15 351 810204 75929 109702815
Brain herniation 44.67 11.15 6 810549 8857 109769887
Device occlusion 44.66 11.15 28 810527 15157 109763587
Intervertebral disc space narrowing 44.62 11.15 62 810493 1834 109776910
Neoplasm malignant 44.47 11.15 442 810113 36701 109742043
Atrial tachycardia 44.43 11.15 7 810548 9171 109769573
Dissociation 44.41 11.15 9 810546 9833 109768911
Spinal column injury 44.41 11.15 69 810486 2262 109776482
Methaemoglobinaemia 44.37 11.15 7 810548 9161 109769583
Neutrophil count increased 44.02 11.15 120 810435 34532 109744212
Spinal stenosis 43.76 11.15 264 810291 18792 109759952
Hypotonia 43.66 11.15 31 810524 15714 109763030
Intestinal perforation 43.63 11.15 283 810272 20661 109758083
Asphyxia 43.51 11.15 25 810530 14190 109764554
General symptom 43.20 11.15 153 810402 8693 109770051
Stupor 43.11 11.15 5 810550 8260 109770484
Carotid artery thrombosis 43.10 11.15 9 810546 9629 109769115
Hypersomnia 42.97 11.15 88 810467 27973 109750771
Steroid dependence 42.68 11.15 148 810407 8321 109770423
Histoplasmosis 42.37 11.15 77 810478 2876 109775868
Peripheral sensory neuropathy 42.25 11.15 36 810519 16644 109762100
Personality change 42.13 11.15 14 810541 10988 109767756
Loss of therapeutic response 41.94 11.15 70 810485 2440 109776304
Benign prostatic hyperplasia 41.89 11.15 43 810512 18191 109760553
Wrong product administered 41.87 11.15 14 810541 10946 109767798
Feeling abnormal 41.86 11.15 1006 809549 179705 109599039
Blood glucose fluctuation 41.84 11.15 4 810551 7694 109771050
Bronchopulmonary aspergillosis allergic 41.77 11.15 6 810549 8420 109770324
Ventricular hypokinesia 41.68 11.15 15 810540 11199 109767545
Fear 41.56 11.15 66 810489 23127 109755617
Bundle branch block right 41.52 11.15 19 810536 12272 109766472
Clonus 41.41 11.15 7 810548 8709 109770035
Proteinuria 41.41 11.15 152 810403 39866 109738878
Arthritis bacterial 41.25 11.15 173 810382 10647 109768097
Product dose omission in error 41.10 11.15 68 810487 23444 109755300
Rash morbilliform 41.00 11.15 5 810550 7946 109770798
Precancerous cells present 40.98 11.15 49 810506 1244 109777500
Enterocolitis 40.97 11.15 47 810508 18902 109759842
Dry mouth 40.95 11.15 1825 808730 198123 109580621
Intestinal polyp 40.93 11.15 68 810487 2361 109776383
Gastrointestinal infection 40.85 11.15 207 810348 13798 109764946
Metabolic encephalopathy 40.76 11.15 15 810540 11045 109767699
Device defective 40.75 11.15 88 810467 3734 109775010
Neck deformity 40.44 11.15 59 810496 1827 109776917
Post procedural inflammation 40.39 11.15 24 810531 217 109778527
Plasmablastic lymphoma 40.35 11.15 39 810516 771 109777973
Electrocardiogram ST segment elevation 40.05 11.15 9 810546 9151 109769593
Sleep disorder due to a general medical condition 40.05 11.15 221 810334 51891 109726853
Protein urine present 39.98 11.15 17 810538 11467 109767277
Euphoric mood 39.98 11.15 8 810547 8819 109769925
Psychomotor retardation 39.94 11.15 5 810550 7787 109770957
Defaecation urgency 39.93 11.15 148 810407 8599 109770145
Joint lock 39.85 11.15 84 810471 3504 109775240
Postoperative abscess 39.75 11.15 41 810514 879 109777865
Scleritis 39.74 11.15 108 810447 5312 109773432
Ecchymosis 39.70 11.15 41 810514 17297 109761447
Clinically isolated syndrome 39.65 11.15 15 810540 40 109778704
Terminal state 39.65 11.15 111 810444 5556 109773188
Eye irritation 39.45 11.15 120 810435 33332 109745412
Brain injury 39.43 11.15 25 810530 13451 109765293
Neck surgery 39.40 11.15 62 810493 2055 109776689
Infusion site reaction 39.36 11.15 243 810312 17439 109761305
Pseudomonal sepsis 39.33 11.15 9 810546 9037 109769707
Female genital tract fistula 39.31 11.15 231 810324 16288 109762456
Postoperative wound infection 39.26 11.15 223 810332 15530 109763214
Partial seizures 39.19 11.15 17 810538 11332 109767412
Hepatitis B virus test positive 39.15 11.15 32 810523 502 109778242
Drug therapy 39.07 11.15 4 810551 7287 109771457
Cholecystectomy 39.03 11.15 170 810385 10639 109768105
Apnoea 38.95 11.15 26 810529 13613 109765131
Quality of life decreased 38.95 11.15 206 810349 13963 109764781
Secretion discharge 38.84 11.15 268 810287 19976 109758768
Pseudopolyposis 38.82 11.15 19 810536 111 109778633
Delirium 38.78 11.15 726 809829 134299 109644445
Restless legs syndrome 38.76 11.15 76 810479 24550 109754194
Lacrimation increased 38.70 11.15 108 810447 30842 109747902
Adhesion 38.68 11.15 51 810504 1433 109777311
Nightmare 38.66 11.15 150 810405 38713 109740031
Failure to thrive 38.60 11.15 26 810529 13548 109765196
Hyperreflexia 38.24 11.15 11 810544 9474 109769270
Multiple fractures 38.12 11.15 148 810407 8792 109769952
Musculoskeletal chest pain 38.08 11.15 98 810457 28749 109749995
Pneumatosis intestinalis 38.07 11.15 8 810547 8521 109770223
Cholangitis sclerosing 37.65 11.15 82 810473 3500 109775244
Anastomotic ulcer 37.49 11.15 43 810512 1043 109777701
Embolic stroke 37.42 11.15 9 810546 8734 109770010
Non-cardiac chest pain 37.30 11.15 14 810541 10184 109768560
Bone marrow oedema 37.20 11.15 61 810494 2095 109776649
Colitis 37.16 11.15 998 809557 101325 109677419
Pulmonary function test decreased 37.15 11.15 9 810546 8691 109770053
Intestinal operation 37.11 11.15 33 810522 584 109778160
Parapsoriasis 37.07 11.15 24 810531 256 109778488
Wrist deformity 36.99 11.15 76 810479 3113 109775631
Appendicectomy 36.96 11.15 79 810476 3328 109775416
Colon dysplasia 36.93 11.15 27 810528 356 109778388
Porphyria acute 36.85 11.15 250 810305 18530 109760214
Postoperative adhesion 36.80 11.15 32 810523 549 109778195
Bone density decreased 36.68 11.15 222 810333 15820 109762924
Blood triglycerides increased 36.67 11.15 75 810480 23851 109754893
Nasal polyps 36.59 11.15 26 810529 13174 109765570
Blood pressure inadequately controlled 36.55 11.15 6 810549 7627 109771117
Gynaecomastia 36.47 11.15 12 810543 9478 109769266
Genital abscess 36.45 11.15 24 810531 264 109778480
Neck mass 36.29 11.15 97 810458 4724 109774020
Candida infection 36.14 11.15 205 810350 47804 109730940
Sarcoid-like reaction 36.09 11.15 25 810530 301 109778443
Peritonitis bacterial 36.02 11.15 16 810539 10517 109768227
Rheumatoid factor negative 35.95 11.15 46 810509 1254 109777490
Aplasia 35.94 11.15 7 810548 7866 109770878
Pneumothorax 35.87 11.15 135 810420 35150 109743594
Unevaluable event 35.83 11.15 622 809933 58605 109720139
Myelodysplastic syndrome 35.82 11.15 147 810408 37337 109741407
Inappropriate schedule of product administration 35.81 11.15 1178 809377 202459 109576285
Klebsiella infection 35.79 11.15 57 810498 19952 109758792
Ventricular dysfunction 35.75 11.15 6 810549 7505 109771239
Hepatic necrosis 35.66 11.15 14 810541 9908 109768836
Synovectomy 35.63 11.15 23 810532 244 109778500
Tricuspid valve incompetence 35.60 11.15 76 810479 23797 109754947
Cerebral haematoma 35.60 11.15 13 810542 9619 109769125
Amylase increased 35.57 11.15 24 810531 12495 109766249
Blood immunoglobulin E increased 35.56 11.15 6 810549 7476 109771268
Decubitus ulcer 35.49 11.15 49 810506 18187 109760557
Escherichia bacteraemia 35.46 11.15 15 810540 10149 109768595
Choking 35.43 11.15 35 810520 15075 109763669
Post procedural infection 35.42 11.15 197 810358 13612 109765132
Arteriosclerosis 35.17 11.15 81 810474 24686 109754058
Psychomotor skills impaired 35.05 11.15 5 810550 7053 109771691
Purulent discharge 35.02 11.15 123 810432 6960 109771784
Hypertriglyceridaemia 35.00 11.15 40 810515 16114 109762630
Injection site irritation 35.00 11.15 97 810458 4827 109773917
Ventricular hypertrophy 34.96 11.15 5 810550 7040 109771704
Incisional hernia 34.90 11.15 68 810487 2679 109776065
Papilloma viral infection 34.89 11.15 59 810496 2079 109776665
Cholecystitis 34.89 11.15 87 810468 25795 109752949
Haematochezia 34.89 11.15 1101 809454 114423 109664321
Sensory loss 34.84 11.15 65 810490 21392 109757352
Pneumonia fungal 34.80 11.15 34 810521 14720 109764024
Joint warmth 34.70 11.15 58 810497 2024 109776720
Malignant melanoma stage I 34.65 11.15 19 810536 145 109778599
Proctectomy 34.61 11.15 25 810530 323 109778421
Hyperlactacidaemia 34.55 11.15 9 810546 8277 109770467
Duodenal ulcer 34.52 11.15 56 810499 19458 109759286
Device malfunction 34.50 11.15 312 810243 25246 109753498
Abscess rupture 34.44 11.15 26 810529 361 109778383
Paradoxical drug reaction 34.38 11.15 153 810402 9664 109769080
Product prescribing issue 34.31 11.15 26 810529 12746 109765998
Mass 34.25 11.15 254 810301 19376 109759368
Performance status decreased 34.16 11.15 6 810549 7260 109771484
Pulmonary vasculitis 34.14 11.15 4 810551 6556 109772188
Arteriospasm coronary 34.12 11.15 12 810543 9088 109769656
Bone cyst 33.98 11.15 79 810476 3524 109775220
Osteoporotic fracture 33.92 11.15 101 810454 5236 109773508
Kidney infection 33.80 11.15 311 810244 25288 109753456
Pulmonary mass 33.73 11.15 420 810135 36881 109741863
Weight decreased 33.56 11.15 2963 807592 465094 109313650
Bursitis infective staphylococcal 33.51 11.15 15 810540 69 109778675
Arthroscopy 33.50 11.15 32 810523 623 109778121
Respiratory syncytial virus infection 33.45 11.15 34 810521 14450 109764294
Anorectal swelling 33.42 11.15 18 810537 132 109778612
Myocardial infarction 33.35 11.15 1113 809442 190970 109587774
Dyshidrotic eczema 33.30 11.15 34 810521 720 109778024
Autoimmune haemolytic anaemia 33.19 11.15 18 810537 10549 109768195
Pain in jaw 33.11 11.15 229 810326 50948 109727796
Product prescribing error 33.05 11.15 230 810325 51101 109727643
Nail psoriasis 33.00 11.15 33 810522 681 109778063
Gastrointestinal pain 32.99 11.15 173 810382 11687 109767057
Intestinal ischaemia 32.99 11.15 42 810513 16137 109762607
Rhinovirus infection 32.97 11.15 23 810532 11766 109766978
Hip fracture 32.87 11.15 139 810416 35012 109743732
Red cell distribution width decreased 32.87 11.15 59 810496 2182 109776562
Disease susceptibility 32.79 11.15 24 810531 317 109778427
Catheter site infection 32.77 11.15 9 810546 7991 109770753
Hodgkin's disease 32.68 11.15 35 810520 785 109777959
Lipase increased 32.64 11.15 54 810501 18618 109760126
Sinus congestion 32.64 11.15 114 810441 30345 109748399
Cytology abnormal 32.48 11.15 24 810531 322 109778422
Sputum discoloured 32.42 11.15 101 810454 27844 109750900
Breast cancer stage II 32.40 11.15 325 810230 27050 109751694
Staphylococcal bacteraemia 32.32 11.15 45 810510 16643 109762101
Anorectal disorder 32.29 11.15 66 810489 2693 109776051
Treatment delayed 32.26 11.15 28 810527 479 109778265
Renal disorder 32.21 11.15 221 810334 49258 109729486
Purpura 32.08 11.15 83 810472 24305 109754439
Product complaint 32.04 11.15 33 810522 13939 109764805
Polychondritis 31.99 11.15 37 810518 906 109777838
Interstitial lung disease 31.90 11.15 777 809778 138557 109640187
Obsessive-compulsive disorder 31.89 11.15 7 810548 7234 109771510
Exercise tolerance decreased 31.86 11.15 25 810530 12042 109766702
Brain death 31.85 11.15 5 810550 6568 109772176
Colostomy closure 31.82 11.15 18 810537 147 109778597
Subcutaneous abscess 31.73 11.15 144 810411 9173 109769571
Laryngeal disorder 31.65 11.15 41 810514 1132 109777612
Muscle haemorrhage 31.58 11.15 6 810549 6863 109771881
Electroencephalogram abnormal 31.54 11.15 4 810551 6169 109772575
Swelling face 31.52 11.15 481 810074 91840 109686904
Pruritus genital 31.52 11.15 5 810550 6517 109772227
Antiphospholipid syndrome 31.50 11.15 62 810493 2461 109776283
Mucous stools 31.38 11.15 116 810439 6731 109772013
Adenovirus infection 31.34 11.15 21 810534 10973 109767771
Psoriasis area severity index increased 31.20 11.15 22 810533 273 109778471
Skin exfoliation 31.19 11.15 453 810102 87198 109691546
Gastrointestinal anastomotic stenosis 31.18 11.15 14 810541 65 109778679
Duodenal ulcer haemorrhage 31.17 11.15 10 810545 8027 109770717
Jejunal stenosis 31.08 11.15 17 810538 129 109778615
Thrombotic thrombocytopenic purpura 31.07 11.15 7 810548 7104 109771640
Lung opacity 30.94 11.15 24 810531 11628 109767116
Behaviour disorder 30.93 11.15 16 810539 9631 109769113
Ocular sarcoidosis 30.92 11.15 16 810539 107 109778637
Complication of device insertion 30.90 11.15 13 810542 8825 109769919
Left ventricular dysfunction 30.87 11.15 80 810475 23413 109755331
Drug screen positive 30.78 11.15 5 810550 6405 109772339
Tongue oedema 30.76 11.15 11 810544 8245 109770499
Eyelid oedema 30.73 11.15 40 810515 15222 109763522
Short-bowel syndrome 30.71 11.15 33 810522 743 109778001
Enteritis 30.71 11.15 243 810312 18913 109759831
Pulmonary thrombosis 30.53 11.15 190 810365 13673 109765071
Peritoneal tuberculosis 30.51 11.15 29 810526 561 109778183
Prostatic specific antigen increased 30.48 11.15 28 810527 12483 109766261
Perirectal abscess 30.48 11.15 57 810498 2177 109776567
Upper-airway cough syndrome 30.47 11.15 43 810512 15814 109762930
Tropical infectious disease 30.47 11.15 12 810543 37 109778707
Throat tightness 30.36 11.15 134 810421 33355 109745389
Anosmia 30.29 11.15 28 810527 12444 109766300
Proctocolectomy 30.23 11.15 20 810535 222 109778522
Large intestine anastomosis 30.18 11.15 15 810540 91 109778653
Alopecia areata 30.08 11.15 56 810499 2131 109776613
Acute graft versus host disease in skin 29.97 11.15 21 810534 10719 109768025
Conjunctivitis allergic 29.93 11.15 7 810548 6924 109771820
Haemorrhoidal haemorrhage 29.78 11.15 11 810544 8082 109770662
Visual acuity reduced 29.61 11.15 128 810427 32045 109746699
Catheter site haemorrhage 29.59 11.15 4 810551 5876 109772868
Priapism 29.46 11.15 4 810551 5857 109772887
Ectopic pregnancy 29.35 11.15 57 810498 2240 109776504
Nail operation 29.32 11.15 48 810507 1646 109777098
Catarrh 29.32 11.15 119 810436 7216 109771528
Conjunctival hyperaemia 29.26 11.15 4 810551 5827 109772917
Perineal rash 29.14 11.15 14 810541 78 109778666
Pleuropericarditis 29.13 11.15 30 810525 642 109778102
Hyperammonaemic encephalopathy 29.07 11.15 3 810552 5431 109773313
Intra-abdominal fluid collection 28.98 11.15 77 810478 3737 109775007
Autonomic nervous system imbalance 28.93 11.15 4 810551 5776 109772968
Drug abuser 28.90 11.15 3 810552 5406 109773338
Bone density abnormal 28.85 11.15 78 810477 3825 109774919
Metabolic disorder 28.74 11.15 21 810534 10489 109768255
Retinal toxicity 28.71 11.15 47 810508 1612 109777132
Cholecystitis chronic 28.66 11.15 17 810538 9483 109769261
Tenosynovitis stenosans 28.66 11.15 74 810481 3529 109775215
Optic neuritis 28.57 11.15 159 810396 10988 109767756
Type I hypersensitivity 28.53 11.15 6 810549 6387 109772357
Motor dysfunction 28.46 11.15 88 810467 24318 109754426
Hypertensive crisis 28.33 11.15 88 810467 24284 109754460
Erythrodermic psoriasis 28.32 11.15 52 810503 1958 109776786
Infiltration anaesthesia 28.31 11.15 17 810538 157 109778587
Catheter site erythema 28.29 11.15 5 810550 6023 109772721
Parainfluenzae virus infection 28.28 11.15 8 810547 6966 109771778
Immune-mediated lung disease 28.18 11.15 3 810552 5300 109773444
Spinal pain 28.12 11.15 232 810323 18283 109760461
Therapy partial responder 28.03 11.15 158 810397 36903 109741841
Transplant failure 27.96 11.15 4 810551 5631 109773113
Vulval disorder 27.96 11.15 34 810521 879 109777865
Hunger 27.87 11.15 7 810548 6597 109772147
Gastric haemorrhage 27.85 11.15 46 810509 15869 109762875
Postoperative wound complication 27.84 11.15 46 810509 1590 109777154
Synovial fluid analysis 27.75 11.15 61 810494 2620 109776124
Colitis ischaemic 27.75 11.15 55 810500 17695 109761049
Human herpesvirus 6 infection 27.73 11.15 7 810548 6574 109772170
Respiratory rate decreased 27.66 11.15 6 810549 6252 109772492
Mean platelet volume decreased 27.52 11.15 69 810486 3231 109775513
Cross sensitivity reaction 27.51 11.15 4 810551 5563 109773181
Graft versus host disease in skin 27.51 11.15 13 810542 8241 109770503
Atelectasis 27.50 11.15 157 810398 36555 109742189
Blindness 27.50 11.15 155 810400 36204 109742540
Glaucomatocyclitic crises 27.46 11.15 7 810548 0 109778744
Wrist surgery 27.29 11.15 33 810522 848 109777896
Prolonged labour 27.28 11.15 25 810530 461 109778283
Stenotrophomonas infection 27.19 11.15 5 810550 5853 109772891
Anger 27.12 11.15 62 810493 18945 109759799
Multiple sclerosis 27.08 11.15 298 810257 25400 109753344
Sensitivity to weather change 27.02 11.15 145 810410 9883 109768861
Pulmonary arterial pressure increased 27.00 11.15 3 810552 5124 109773620
Cardiac failure chronic 26.99 11.15 37 810518 13774 109764970
Poor quality sleep 26.89 11.15 110 810445 27967 109750777
Cyst 26.85 11.15 210 810345 16286 109762458
Initial insomnia 26.83 11.15 22 810533 10367 109768377
Ileocolectomy 26.69 11.15 13 810542 75 109778669
Drain placement 26.67 11.15 18 810537 207 109778537
Inadequate analgesia 26.66 11.15 3 810552 5074 109773670
Blood test abnormal 26.65 11.15 113 810442 28441 109750303
Somnambulism 26.62 11.15 7 810548 6398 109772346
Granulomatous lymphadenitis 26.61 11.15 24 810531 433 109778311
SAPHO syndrome 26.59 11.15 27 810528 568 109778176
Fungaemia 26.57 11.15 6 810549 6080 109772664
Lumbosacral plexopathy 26.53 11.15 14 810541 98 109778646
Walking aid user 26.52 11.15 291 810264 24784 109753960
Neutrophilia 26.52 11.15 22 810533 10307 109768437
Hypoventilation 26.52 11.15 13 810542 8068 109770676
Spinal fusion surgery 26.47 11.15 135 810420 9021 109769723
Allergy to vaccine 26.46 11.15 18 810537 210 109778534
Purulence 26.45 11.15 55 810500 2272 109776472
Colonoscopy abnormal 26.29 11.15 17 810538 181 109778563
Hypertension 26.23 11.15 4189 806366 505895 109272849
Cerebral ischaemia 26.19 11.15 30 810525 12074 109766670
Urinary tract infection 26.17 11.15 2047 808508 324235 109454509
Taste disorder 26.15 11.15 646 809909 64741 109714003
Iris adhesions 26.04 11.15 28 810527 631 109778113
Stoma obstruction 26.00 11.15 20 810535 286 109778458
Vein rupture 25.99 11.15 58 810497 2517 109776227
Ammonia increased 25.99 11.15 14 810541 8236 109770508
Neurological decompensation 25.94 11.15 9 810546 6874 109771870
Thrombosis in device 25.93 11.15 4 810551 5323 109773421
Refusal of treatment by patient 25.92 11.15 19 810536 9475 109769269
Tinnitus 25.92 11.15 301 810254 60239 109718505
Exposure via skin contact 25.92 11.15 35 810520 13112 109765632
Eye movement disorder 25.88 11.15 20 810535 9708 109769036
Arthritis reactive 25.87 11.15 31 810524 789 109777955
Hepatomegaly 25.84 11.15 76 810479 21338 109757406
Rotator cuff syndrome 25.81 11.15 211 810344 16583 109762161
Diabetes insipidus 25.80 11.15 8 810547 6562 109772182
Small intestine operation 25.77 11.15 11 810544 44 109778700
Neuritis 25.68 11.15 11 810544 7388 109771356
Rebound psoriasis 25.62 11.15 18 810537 222 109778522
Immune thrombocytopenia 25.60 11.15 82 810473 22412 109756332
Gait disturbance 25.57 11.15 2370 808185 275838 109502906
Self-medication 25.55 11.15 7 810548 6225 109772519
Hepatic enzyme abnormal 25.52 11.15 140 810415 9623 109769121
Tongue disorder 25.51 11.15 186 810369 14112 109764632
Diastolic dysfunction 25.50 11.15 32 810523 12372 109766372
Tonsillectomy 25.48 11.15 31 810524 802 109777942
Nephropathy 25.40 11.15 37 810518 13430 109765314
Post procedural fistula 25.32 11.15 23 810532 419 109778325
Tension headache 25.30 11.15 20 810535 9598 109769146
Ulcer haemorrhage 25.30 11.15 265 810290 22306 109756438
Klebsiella bacteraemia 25.26 11.15 3 810552 4866 109773878
Mitral valve incompetence 25.25 11.15 142 810413 33187 109745557
Colostomy 25.24 11.15 41 810514 1397 109777347
Congestive hepatopathy 25.23 11.15 4 810551 5216 109773528
Pericardial haemorrhage 25.21 11.15 4 810551 5213 109773531
Bladder transitional cell carcinoma stage II 25.10 11.15 12 810543 66 109778678
Fracture 25.09 11.15 95 810460 24693 109754051
Respiration abnormal 25.05 11.15 21 810534 9788 109768956
Enterostomy 25.01 11.15 17 810538 198 109778546
Endotracheal intubation 25.00 11.15 7 810548 6137 109772607
Fracture delayed union 25.00 11.15 52 810503 2149 109776595
Petit mal epilepsy 24.98 11.15 12 810543 7535 109771209
Arteriosclerosis coronary artery 24.95 11.15 97 810458 25021 109753723
Neutropenic colitis 24.95 11.15 14 810541 8051 109770693
Central nervous system inflammation 24.95 11.15 21 810534 344 109778400
Large intestinal obstruction 24.88 11.15 74 810481 3834 109774910
Hepatitis fulminant 24.88 11.15 16 810539 8544 109770200
Antisynthetase syndrome 24.80 11.15 19 810536 270 109778474
Bladder transitional cell carcinoma 24.67 11.15 60 810495 2756 109775988
Upper respiratory tract infection 24.58 11.15 1188 809367 130140 109648604
Prosthesis user 24.53 11.15 12 810543 70 109778674
Heavy exposure to ultraviolet light 24.51 11.15 11 810544 51 109778693
International normalised ratio abnormal 24.50 11.15 8 810547 6349 109772395
Thyroiditis subacute 24.49 11.15 23 810532 438 109778306
Haematocrit decreased 24.48 11.15 339 810216 65778 109712966
Hydronephrosis 24.46 11.15 74 810481 20591 109758153
Skin abrasion 24.44 11.15 51 810504 16100 109762644
Gastroenteritis 24.42 11.15 175 810380 38625 109740119
Hysterectomy 24.42 11.15 121 810434 7993 109770751
Diffuse alopecia 24.39 11.15 39 810516 1311 109777433
Infected fistula 24.37 11.15 24 810531 486 109778258
Drug level decreased 24.32 11.15 225 810330 18323 109760421
Tension 24.30 11.15 4 810551 5074 109773670
Mycobacterium marinum infection 24.26 11.15 29 810526 736 109778008
Femoral neck fracture 24.23 11.15 34 810521 12533 109766211
Atrioventricular block second degree 24.18 11.15 15 810540 8166 109770578
Body height decreased 24.16 11.15 25 810530 10538 109768206
Blood phosphorus decreased 24.15 11.15 13 810542 7652 109771092
Injury associated with device 24.15 11.15 79 810476 4310 109774434
Stoma site abscess 24.15 11.15 20 810535 320 109778424
Pyelonephritis 24.14 11.15 99 810456 25151 109753593
Thyroiditis 24.08 11.15 9 810546 6564 109772180
Abortion spontaneous 24.08 11.15 369 810186 33913 109744831
Total lung capacity decreased 24.03 11.15 11 810544 7103 109771641
Product physical issue 24.02 11.15 4 810551 5032 109773712
Nasal oedema 24.01 11.15 10 810545 6829 109771915
Swollen tongue 23.99 11.15 305 810250 60057 109718687
Cholelithiasis 23.91 11.15 324 810231 63098 109715646
Blood glucose abnormal 23.86 11.15 36 810519 12880 109765864
Accidental death 23.85 11.15 4 810551 5005 109773739
Lip oedema 23.79 11.15 13 810542 7587 109771157
Drug dependence 23.69 11.15 243 810312 49777 109728967
Compression fracture 23.64 11.15 20 810535 9279 109769465
Cutaneous B-cell lymphoma 23.61 11.15 14 810541 126 109778618
Hyperuricaemia 23.61 11.15 44 810511 14487 109764257
Legionella infection 23.61 11.15 32 810523 924 109777820
Areflexia 23.60 11.15 10 810545 6759 109771985
Thinking abnormal 23.59 11.15 47 810508 15093 109763651
Complication of device removal 23.59 11.15 3 810552 4617 109774127
Syringe issue 23.59 11.15 21 810534 9504 109769240
Systemic candida 23.51 11.15 23 810532 9951 109768793
Lung cancer metastatic 23.49 11.15 76 810479 4122 109774622
Histone antibody positive 23.49 11.15 15 810540 156 109778588
Gastric ulcer 23.46 11.15 183 810372 39644 109739100
Ileocolostomy 23.43 11.15 10 810545 40 109778704
Skin lesion 23.38 11.15 519 810036 51112 109727632
Vascular access complication 23.37 11.15 55 810500 2473 109776271
Tumour haemorrhage 23.25 11.15 5 810550 5240 109773504
Decreased interest 23.19 11.15 4 810551 4904 109773840
Capillary leak syndrome 23.19 11.15 4 810551 4904 109773840
Generalised oedema 23.17 11.15 131 810424 30573 109748171
Cutaneous lupus erythematosus 23.12 11.15 67 810488 3421 109775323
Pneumonia cytomegaloviral 23.10 11.15 11 810544 6943 109771801
N-terminal prohormone brain natriuretic peptide increased 23.07 11.15 8 810547 6113 109772631
Intestinal mass 23.01 11.15 40 810515 1442 109777302
Exposure to communicable disease 22.95 11.15 25 810530 572 109778172
Poor venous access 22.91 11.15 97 810458 24425 109754319
Mite allergy 22.90 11.15 7 810548 5796 109772948
Juvenile idiopathic arthritis 22.86 11.15 96 810459 5911 109772833
Atrial septal defect acquired 22.79 11.15 9 810546 28 109778716
Bundle branch block left 22.78 11.15 37 810518 12851 109765893
Stridor 22.77 11.15 11 810544 6884 109771860
Hypersensitivity vasculitis 22.72 11.15 106 810449 6831 109771913
Breast cancer 22.68 11.15 403 810152 38139 109740605
Nystagmus 22.64 11.15 31 810524 11546 109767198
Coccidioidomycosis 22.62 11.15 42 810513 1595 109777149
Testis cancer 22.62 11.15 37 810518 1268 109777476
Dysplasia 22.58 11.15 45 810510 1803 109776941
Enterococcal bacteraemia 22.53 11.15 3 810552 4458 109774286
Head discomfort 22.52 11.15 68 810487 18932 109759812
Hypokinesia 22.51 11.15 83 810472 21743 109757001
Small intestinal anastomosis 22.40 11.15 8 810547 17 109778727
Rash pustular 22.38 11.15 166 810389 12663 109766081
Subdural haemorrhage 22.37 11.15 10 810545 6548 109772196
Red blood cell count decreased 22.32 11.15 344 810211 65579 109713165
Enterovesical fistula 22.27 11.15 39 810516 1414 109777330
Vulvovaginal erythema 22.27 11.15 23 810532 494 109778250
Drug level abnormal 22.24 11.15 24 810531 543 109778201
Rash macular 22.22 11.15 179 810376 38507 109740237
Respiratory tract infection 22.16 11.15 380 810175 71237 109707507
Post procedural swelling 22.11 11.15 27 810528 701 109778043
Brachiocephalic artery stenosis 22.11 11.15 9 810546 31 109778713
Rash pruritic 22.06 11.15 904 809651 97165 109681579
Disturbance in social behaviour 22.06 11.15 5 810550 5053 109773691
Tubulointerstitial nephritis 22.05 11.15 273 810282 54011 109724733
Stoma site ulcer 22.04 11.15 18 810537 282 109778462
Temperature intolerance 22.00 11.15 43 810512 13907 109764837
Gliosis 22.00 11.15 27 810528 705 109778039
Granulomatous dermatitis 21.94 11.15 23 810532 503 109778241
Pseudomonal bacteraemia 21.93 11.15 3 810552 4368 109774376
Genital haemorrhage 21.85 11.15 13 810542 7239 109771505
Bronchial secretion retention 21.84 11.15 5 810550 5019 109773725
Atrial thrombosis 21.77 11.15 3 810552 4343 109774401
Subacute inflammatory demyelinating polyneuropathy 21.74 11.15 7 810548 9 109778735
Therapeutic response changed 21.72 11.15 41 810514 1577 109777167
Seasonal allergy 21.68 11.15 73 810482 19649 109759095
Burns second degree 21.65 11.15 113 810442 7620 109771124
Chronic disease 21.63 11.15 16 810539 215 109778529
Acute psychosis 21.61 11.15 5 810550 4982 109773762
Multiple-drug resistance 21.57 11.15 40 810515 13195 109765549
Endophthalmitis 21.57 11.15 17 810538 8170 109770574
Hip surgery 21.53 11.15 73 810482 4057 109774687
Subcutaneous drug absorption impaired 21.50 11.15 112 810443 7547 109771197
Hypertonia 21.46 11.15 18 810537 8388 109770356
Product substitution 21.42 11.15 14 810541 152 109778592
Urine abnormality 21.41 11.15 21 810534 9075 109769669
Cardiopulmonary failure 21.34 11.15 16 810539 7887 109770857
Oesophageal varices haemorrhage 21.34 11.15 5 810550 4940 109773804
Eye swelling 21.32 11.15 148 810407 32900 109745844
Incoherent 21.22 11.15 18 810537 8340 109770404
Sinus node dysfunction 21.17 11.15 21 810534 9026 109769718
Peritoneal cyst 21.13 11.15 6 810549 3 109778741
Periorbital swelling 21.09 11.15 7 810548 5498 109773246
Angioimmunoblastic T-cell lymphoma 21.08 11.15 25 810530 629 109778115
Post procedural sepsis 21.02 11.15 27 810528 739 109778005
Stoma creation 21.02 11.15 15 810540 190 109778554
Fixed eruption 21.01 11.15 3 810552 4229 109774515
Supraventricular extrasystoles 20.97 11.15 17 810538 8056 109770688
Hernia 20.95 11.15 227 810328 19273 109759471
Anal ulcer 20.93 11.15 44 810511 1832 109776912
Stress at work 20.88 11.15 36 810519 1289 109777455
Anal fissure 20.88 11.15 134 810421 9747 109768997
Gastrointestinal bacterial overgrowth 20.81 11.15 25 810530 638 109778106
Normochromic normocytic anaemia 20.81 11.15 40 810515 13017 109765727
Small intestine adenocarcinoma 20.79 11.15 16 810539 229 109778515
Vasculitic rash 20.75 11.15 49 810506 2208 109776536
Left ventricular hypertrophy 20.74 11.15 41 810514 13203 109765541
Vascular pseudoaneurysm 20.73 11.15 3 810552 4187 109774557
Vulvovaginal swelling 20.71 11.15 24 810531 589 109778155
Injection site vesicles 20.70 11.15 76 810479 4395 109774349
Cutaneous lymphoma 20.68 11.15 17 810538 269 109778475
Adenocarcinoma of the cervix 20.68 11.15 16 810539 231 109778513
Cold sweat 20.67 11.15 87 810468 21944 109756800
Herpes simplex oesophagitis 20.63 11.15 21 810534 443 109778301
Neurological symptom 20.62 11.15 53 810502 15555 109763189
Rebound effect 20.56 11.15 49 810506 14757 109763987
Skin hyperpigmentation 20.56 11.15 20 810535 8676 109770068
Cardiomegaly 20.54 11.15 127 810428 29003 109749741
Short stature 20.46 11.15 32 810523 1055 109777689
Blood immunoglobulin G decreased 20.45 11.15 7 810548 5393 109773351
Cardiac dysfunction 20.44 11.15 10 810545 6213 109772531
Weight increased 20.40 11.15 3436 807119 416208 109362536
Blood chloride decreased 20.37 11.15 22 810533 9093 109769651
Osteonecrosis 20.36 11.15 154 810401 33587 109745157
Gastritis 20.36 11.15 274 810281 53425 109725319
Craniocerebral injury 20.32 11.15 9 810546 5925 109772819
Local reaction 20.31 11.15 27 810528 765 109777979
Pulmonary sarcoidosis 20.28 11.15 42 810513 1730 109777014
Bile acid malabsorption 20.26 11.15 21 810534 453 109778291
Hepatitis 20.23 11.15 830 809725 89224 109689520
Hypocholesterolaemia 20.22 11.15 97 810458 6324 109772420
Gastroenterostomy 20.21 11.15 10 810545 60 109778684
Autoantibody positive 20.21 11.15 13 810542 137 109778607
Arterial occlusive disease 20.21 11.15 52 810503 15256 109763488
Temperature regulation disorder 20.18 11.15 162 810393 12664 109766080
Viraemia 20.15 11.15 3 810552 4099 109774645
Groin pain 20.15 11.15 187 810368 15241 109763503
Hypoacusis 20.13 11.15 163 810392 35028 109743716
Renal colic 20.09 11.15 61 810494 3197 109775547
Skin mass 20.06 11.15 132 810423 9684 109769060
Acute coronary syndrome 20.04 11.15 94 810461 23018 109755726
T-cell lymphoma 20.01 11.15 39 810516 1537 109777207
Tonsillar hypertrophy 19.95 11.15 44 810511 1894 109776850
Renal tubular acidosis 19.89 11.15 5 810550 4710 109774034
Breast cancer stage I 19.89 11.15 15 810540 7372 109771372
Dry throat 19.88 11.15 23 810532 9215 109769529
Cytomegalovirus chorioretinitis 19.81 11.15 14 810541 7114 109771630
Graft versus host disease in gastrointestinal tract 19.65 11.15 22 810533 8946 109769798
Asthma 19.63 11.15 1573 808982 248718 109530026
Plasmacytoma 19.62 11.15 7 810548 5255 109773489
Infection transmission via personal contact 19.62 11.15 5 810550 0 109778744
Obliterative bronchiolitis 19.58 11.15 66 810489 3657 109775087
Facial pain 19.57 11.15 53 810502 15286 109763458
Embolism 19.52 11.15 58 810497 16231 109762513
Thymoma benign 19.51 11.15 9 810546 45 109778699
Rib fracture 19.51 11.15 156 810399 33614 109745130
Pancreatic steatosis 19.48 11.15 42 810513 1780 109776964
Blood prolactin increased 19.44 11.15 5 810550 4637 109774107
Paracoccidioides infection 19.43 11.15 11 810544 90 109778654
Incorrect drug administration rate 19.42 11.15 8 810547 5500 109773244
Paronychia 19.41 11.15 32 810523 11049 109767695
Anorectal stenosis 19.36 11.15 9 810546 46 109778698
Myxoid liposarcoma 19.35 11.15 8 810547 29 109778715
Granulocyte count decreased 19.31 11.15 3 810552 3971 109774773
Thrombosis 19.24 11.15 628 809927 108034 109670710
Aortic elongation 19.23 11.15 13 810542 150 109778594
Ear pruritus 19.22 11.15 15 810540 7245 109771499
Anal hypoaesthesia 19.20 11.15 9 810546 47 109778697
Intervertebral disc annular tear 19.20 11.15 9 810546 47 109778697
Disseminated large cell lymphoma 19.19 11.15 10 810545 68 109778676
Colectomy total 19.19 11.15 21 810534 483 109778261
Chronic cutaneous lupus erythematosus 19.18 11.15 30 810525 989 109777755
Hepatorenal syndrome 19.16 11.15 5 810550 4592 109774152
Orthopnoea 19.15 11.15 32 810523 10989 109767755
Hepatitis B reactivation 19.14 11.15 16 810539 7468 109771276
Pyoderma 19.14 11.15 22 810533 535 109778209
Liver transplant 19.11 11.15 5 810550 4584 109774160
Paralysis 19.09 11.15 55 810500 15545 109763199
Selective abortion 19.05 11.15 9 810546 48 109778696
Hypermobility syndrome 19.04 11.15 22 810533 538 109778206
Dermal cyst 19.04 11.15 59 810496 3127 109775617
Nephrogenic anaemia 19.03 11.15 5 810550 4572 109774172
Extrapulmonary tuberculosis 19.01 11.15 22 810533 539 109778205
Tuberculosis gastrointestinal 18.96 11.15 23 810532 593 109778151
Atypical femur fracture 18.95 11.15 11 810544 6208 109772536
Liver transplant rejection 18.94 11.15 3 810552 3915 109774829
Spinal meningioma benign 18.93 11.15 11 810544 95 109778649
Anal skin tags 18.88 11.15 22 810533 543 109778201
Nerve block 18.87 11.15 26 810529 763 109777981
Perineal fistula 18.85 11.15 12 810543 124 109778620
Scar 18.83 11.15 198 810357 16683 109762061
Dyspnoea at rest 18.81 11.15 20 810535 8326 109770418
Acne cystic 18.79 11.15 28 810527 884 109777860
Non-consummation 18.75 11.15 9 810546 50 109778694
Injection site inflammation 18.75 11.15 77 810478 4694 109774050
Proctalgia 18.67 11.15 163 810392 13059 109765685
Mesenteritis 18.66 11.15 18 810537 355 109778389
Hypoaesthesia oral 18.65 11.15 63 810492 16939 109761805
Anorectal ulcer 18.61 11.15 9 810546 51 109778693
Sudden cardiac death 18.60 11.15 9 810546 5628 109773116
Deafness neurosensory 18.57 11.15 26 810529 9593 109769151
Blood urine present 18.53 11.15 103 810452 24142 109754602
Scarlet fever 18.53 11.15 13 810542 160 109778584
Back pain 18.47 11.15 2409 808146 368587 109410157
Hereditary angioedema 18.45 11.15 15 810540 7099 109771645
Intra-abdominal haemorrhage 18.45 11.15 8 810547 5334 109773410
Dermatitis acneiform 18.45 11.15 41 810514 12654 109766090
Glioblastoma 18.44 11.15 44 810511 1996 109776748
Flatulence 18.38 11.15 270 810285 51879 109726865
Overwork 18.33 11.15 9 810546 53 109778691
Oxygen therapy 18.32 11.15 4 810551 4149 109774595
Mass excision 18.30 11.15 18 810537 364 109778380
Ischaemic cardiomyopathy 18.28 11.15 19 810536 7992 109770752
Periorbital oedema 18.26 11.15 29 810526 10163 109768581
Back disorder 18.24 11.15 234 810321 20688 109758056
Visceral leishmaniasis 18.23 11.15 40 810515 1716 109777028
Procedural pain 18.22 11.15 364 810191 35201 109743543
Gastrointestinal tract adenoma 18.20 11.15 22 810533 565 109778179
Skin wound 18.20 11.15 45 810510 2089 109776655
Device use error 18.12 11.15 24 810531 9065 109769679
Lymphadenopathy mediastinal 18.11 11.15 84 810471 5400 109773344
Diplopia 18.05 11.15 208 810347 41686 109737058
Rectal cancer 18.05 11.15 65 810490 3724 109775020
Hypertransaminasaemia 18.02 11.15 104 810451 24151 109754593
Incontinence 18.00 11.15 62 810493 16573 109762171
Labelled drug-drug interaction issue 17.99 11.15 4 810551 4097 109774647
Femur fracture 17.98 11.15 440 810115 44029 109734715
Haemolytic uraemic syndrome 17.97 11.15 7 810548 4978 109773766
Hair colour changes 17.97 11.15 6 810549 4695 109774049
Intracranial pressure increased 17.93 11.15 31 810524 10504 109768240
Animal bite 17.90 11.15 56 810499 2983 109775761
Ankle arthroplasty 17.88 11.15 50 810505 2501 109776243
Myelitis 17.83 11.15 58 810497 3155 109775589
Gastric ulcer haemorrhage 17.83 11.15 29 810526 10065 109768679
Skin reaction 17.82 11.15 235 810320 20909 109757835
Immune system disorder 17.81 11.15 164 810391 13337 109765407
Lymphatic fistula 17.78 11.15 36 810519 1459 109777285
Streptococcal bacteraemia 17.78 11.15 6 810549 4663 109774081
Amenorrhoea 17.77 11.15 25 810530 9206 109769538
Occult blood positive 17.74 11.15 17 810538 7428 109771316
Skin weeping 17.74 11.15 3 810552 3732 109775012
SARS-CoV-2 test positive 17.67 11.15 196 810359 16739 109762005
Colon neoplasm 17.67 11.15 28 810527 934 109777810
Meningoradiculitis 17.65 11.15 14 810541 210 109778534
Subcorneal pustular dermatosis 17.64 11.15 10 810545 82 109778662
Cholecystitis acute 17.64 11.15 58 810497 15724 109763020
Low density lipoprotein increased 17.59 11.15 32 810523 10634 109768110
Anaplastic large-cell lymphoma 17.59 11.15 14 810541 211 109778533
Toothache 17.56 11.15 101 810454 23474 109755270
Femoral hernia incarcerated 17.55 11.15 36 810519 1473 109777271
Aortic stenosis 17.52 11.15 44 810511 13015 109765729
Hyperpyrexia 17.46 11.15 20 810535 8049 109770695
Pupillary reflex impaired 17.45 11.15 4 810551 4011 109774733
Joint instability 17.42 11.15 39 810516 1696 109777048
Pharyngeal swelling 17.37 11.15 39 810516 11993 109766751
Pelvic pouch procedure 17.29 11.15 5 810550 3 109778741
Soft tissue disorder 17.25 11.15 61 810494 3463 109775281
Hyperaesthesia 17.24 11.15 53 810502 14674 109764070
Neutrophil count abnormal 17.23 11.15 8 810547 5124 109773620
Premature baby 17.20 11.15 7 810548 4848 109773896
International normalised ratio decreased 17.19 11.15 21 810534 8215 109770529
Conjunctival haemorrhage 17.19 11.15 14 810541 6619 109772125
Haemoperitoneum 17.18 11.15 9 810546 5379 109773365
Pseudomembranous colitis 17.18 11.15 13 810542 6378 109772366
Adenocarcinoma of colon 17.18 11.15 90 810465 6078 109772666
Acute graft versus host disease in intestine 17.14 11.15 10 810545 5629 109773115
Tooth infection 17.12 11.15 243 810312 21973 109756771
Thyroidectomy 17.05 11.15 30 810525 1092 109777652
Odynophagia 17.05 11.15 50 810505 14051 109764693
Eyelid ptosis 17.04 11.15 46 810509 13281 109765463
Dyschezia 17.03 11.15 64 810491 3743 109775001
Extremity contracture 17.03 11.15 39 810516 1722 109777022
Device deployment issue 17.02 11.15 5 810550 4248 109774496
Stricturoplasty 17.01 11.15 7 810548 25 109778719
Oxygen saturation abnormal 16.99 11.15 10 810545 5601 109773143
Blood magnesium decreased 16.94 11.15 82 810473 19914 109758830
Peripheral coldness 16.92 11.15 74 810481 18466 109760278
Scleroderma 16.92 11.15 13 810542 6328 109772416
Lipodystrophy acquired 16.90 11.15 6 810549 4518 109774226
Myoglobin blood increased 16.89 11.15 5 810550 4227 109774517
Enthesophyte 16.88 11.15 12 810543 151 109778593
Superficial spreading melanoma stage unspecified 16.88 11.15 17 810538 354 109778390
Incorrect dosage administered 16.83 11.15 4 810551 3914 109774830
Tumour marker increased 16.82 11.15 8 810547 5052 109773692
Disease recurrence 16.78 11.15 329 810226 60455 109718289
Epigastric discomfort 16.78 11.15 25 810530 8990 109769754
Infectious mononucleosis 16.77 11.15 45 810510 2197 109776547
Epstein-Barr viraemia 16.73 11.15 3 810552 3576 109775168
Hyperthermia malignant 16.72 11.15 4 810551 3896 109774848
Intestinal fistula infection 16.72 11.15 6 810549 13 109778731
Parinaud syndrome 16.72 11.15 6 810549 13 109778731
Drug ineffective for unapproved indication 16.66 11.15 601 809954 102237 109676507
Parakeratosis 16.63 11.15 20 810535 511 109778233
Blood bicarbonate decreased 16.62 11.15 11 810544 5786 109772958
Colonic abscess 16.62 11.15 40 810515 1825 109776919
Embolism venous 16.60 11.15 8 810547 5015 109773729
Platelet count abnormal 16.60 11.15 13 810542 6269 109772475
Acne conglobata 16.60 11.15 7 810548 27 109778717
Haemorrhage subcutaneous 16.59 11.15 10 810545 5529 109773215
Large intestine erosion 16.56 11.15 11 810544 123 109778621
Mental disorder 16.55 11.15 193 810362 38598 109740146
Gastrointestinal erosion 16.55 11.15 30 810525 1118 109777626
Drug specific antibody absent 16.55 11.15 14 810541 231 109778513
Accident 16.51 11.15 137 810418 10815 109767929
Sebaceous gland infection 16.49 11.15 12 810543 157 109778587
Bruxism 16.44 11.15 8 810547 4986 109773758
Galactorrhoea 16.42 11.15 5 810550 4150 109774594
Bone disorder 16.41 11.15 232 810323 20960 109757784
Vertigo 16.36 11.15 498 810057 86372 109692372
Breast cancer metastatic 16.34 11.15 36 810519 11145 109767599
Shoulder operation 16.33 11.15 59 810496 3386 109775358
Stem cell transplant 16.32 11.15 6 810549 4421 109774323
Tooth disorder 16.28 11.15 138 810417 29371 109749373
Normal newborn 16.28 11.15 238 810317 21658 109757086
Acquired hydrocele 16.27 11.15 9 810546 70 109778674
Seminoma 16.26 11.15 15 810540 279 109778465
Quadriplegia 16.25 11.15 5 810550 4122 109774622
Product administered to patient of inappropriate age 16.24 11.15 21 810534 8015 109770729
Mood altered 16.23 11.15 91 810464 21284 109757460
Logorrhoea 16.23 11.15 8 810547 4949 109773795
Drooling 16.21 11.15 17 810538 7122 109771622
Cardiolipin antibody 16.19 11.15 5 810550 5 109778739
Noninfective chorioretinitis 16.19 11.15 5 810550 5 109778739
Bladder neck operation 16.19 11.15 5 810550 5 109778739
Neuroendocrine carcinoma of the skin 16.17 11.15 38 810517 1707 109777037
Gastroenteritis viral 16.13 11.15 320 810235 30906 109747838
Axillary mass 16.13 11.15 24 810531 757 109777987
Post procedural discharge 16.10 11.15 24 810531 758 109777986
Linear IgA disease 16.09 11.15 6 810549 4383 109774361
Cellulitis 16.04 11.15 757 809798 125259 109653485
Urine leukocyte esterase positive 16.00 11.15 4 810551 3782 109774962
Internal haemorrhage 15.92 11.15 31 810524 10040 109768704
Haemorrhagic stroke 15.88 11.15 50 810505 13739 109765005
Eye disorder 15.87 11.15 299 810256 28607 109750137
Pachymeningitis 15.84 11.15 19 810536 484 109778260
Stoma complication 15.84 11.15 28 810527 1023 109777721
Pelvic abscess 15.81 11.15 49 810506 2597 109776147
Myelitis transverse 15.80 11.15 46 810509 2355 109776389
Post-traumatic stress disorder 15.79 11.15 15 810540 6581 109772163
Rectal ulcer 15.77 11.15 48 810507 2519 109776225
Ulnar neuritis 15.72 11.15 5 810550 6 109778738
Inner ear inflammation 15.72 11.15 5 810550 6 109778738
Benign lung neoplasm 15.70 11.15 11 810544 135 109778609
Multiple allergies 15.70 11.15 148 810407 12115 109766629
Ocular fistula 15.69 11.15 4 810551 0 109778744
Laryngeal dysplasia 15.69 11.15 4 810551 0 109778744
Muscular sarcoidosis 15.69 11.15 4 810551 0 109778744
Lip and/or oral cavity cancer stage 0 15.69 11.15 4 810551 0 109778744
Antibiotic prophylaxis 15.69 11.15 4 810551 0 109778744
Oesophageal squamous cell carcinoma stage III 15.69 11.15 4 810551 0 109778744
Muscle strain 15.61 11.15 37 810518 11165 109767579
Fistula inflammation 15.60 11.15 6 810549 17 109778727
Blood thyroid stimulating hormone decreased 15.60 11.15 18 810537 7221 109771523
Troponin T increased 15.60 11.15 6 810549 4300 109774444
Transplant dysfunction 15.59 11.15 23 810532 8305 109770439
Signet-ring cell carcinoma 15.56 11.15 9 810546 77 109778667
Renal function test abnormal 15.52 11.15 26 810529 8920 109769824
Retching 15.42 11.15 100 810455 22582 109756162
Epstein-Barr virus antibody positive 15.40 11.15 22 810533 668 109778076
Urinary tract infection bacterial 15.38 11.15 22 810533 8045 109770699
Urosepsis 15.37 11.15 147 810408 30528 109748216
Paraesthesia 15.36 11.15 2281 808274 274240 109504504
Melkersson-Rosenthal syndrome 15.35 11.15 6 810549 18 109778726
Functional gastrointestinal disorder 15.32 11.15 86 810469 5963 109772781
Hypertonic bladder 15.29 11.15 10 810545 5292 109773452
Staphylococcal abscess 15.28 11.15 31 810524 1258 109777486
Blood parathyroid hormone increased 15.26 11.15 6 810549 4242 109774502
Cerebral atrophy 15.22 11.15 27 810528 9058 109769686
Adenocarcinoma 15.21 11.15 67 810488 4213 109774531
Lower respiratory tract infection viral 15.16 11.15 33 810522 1408 109777336
Bilirubin conjugated increased 15.08 11.15 14 810541 6210 109772534
Portal hypertension 15.08 11.15 25 810530 8612 109770132
Sputum increased 15.08 11.15 12 810543 5739 109773005
Electrocardiogram T wave abnormal 15.07 11.15 6 810549 4211 109774533
Homicidal ideation 15.01 11.15 4 810551 3623 109775121
Thymoma 15.00 11.15 17 810538 407 109778337
Proctitis ulcerative 14.96 11.15 18 810537 460 109778284
Erythema of eyelid 14.96 11.15 5 810550 3910 109774834
Hyperparathyroidism secondary 14.95 11.15 3 810552 3301 109775443
Disorganised speech 14.95 11.15 3 810552 3300 109775444
Gallbladder operation 14.94 11.15 45 810510 2348 109776396
Strongyloidiasis 14.93 11.15 9 810546 4977 109773767
Pustule 14.93 11.15 58 810497 3446 109775298
Intercepted product prescribing error 14.93 11.15 17 810538 409 109778335
Respiratory alkalosis 14.92 11.15 12 810543 5709 109773035
Catheterisation cardiac 14.91 11.15 14 810541 6177 109772567
Hypoproteinaemia 14.85 11.15 13 810542 5932 109772812
Vaginal fistula 14.83 11.15 16 810539 362 109778382
Diffuse vasculitis 14.82 11.15 10 810545 115 109778629
Acute disseminated encephalomyelitis 14.80 11.15 17 810538 413 109778331
Libido decreased 14.80 11.15 13 810542 5922 109772822
Left ventricular failure 14.80 11.15 39 810516 11350 109767394
Non-small cell lung cancer 14.77 11.15 22 810533 7913 109770831
Accident at work 14.75 11.15 30 810525 1220 109777524
Spinal disorder 14.74 11.15 141 810414 11587 109767157
Hepatitis toxic 14.73 11.15 13 810542 5908 109772836
Oligoarthritis 14.71 11.15 23 810532 758 109777986
Autoimmune pancreatitis 14.68 11.15 24 810531 822 109777922
Synovial disorder 14.68 11.15 52 810503 2955 109775789
Hydrocephalus 14.68 11.15 34 810521 10341 109768403
Salivary gland adenoma 14.67 11.15 6 810549 21 109778723
Adhesiolysis 14.67 11.15 6 810549 21 109778723
Bradyarrhythmia 14.65 11.15 9 810546 4925 109773819
Systolic dysfunction 14.64 11.15 7 810548 4408 109774336
B-cell lymphoma stage IV 14.64 11.15 9 810546 87 109778657
Post procedural diarrhoea 14.60 11.15 18 810537 472 109778272
Laryngospasm 14.59 11.15 8 810547 4660 109774084
Economic problem 14.57 11.15 6 810549 4125 109774619
Bladder cancer 14.55 11.15 88 810467 20204 109758540
Urine ketone body present 14.54 11.15 5 810550 3841 109774903
Vaginal operation 14.53 11.15 5 810550 9 109778735
Juvenile spondyloarthritis 14.53 11.15 5 810550 9 109778735
Marginal zone lymphoma 14.53 11.15 13 810542 232 109778512
Cutaneous vasculitis 14.53 11.15 150 810405 12579 109766165
Alcohol use 14.51 11.15 6 810549 4116 109774628
Liver function test decreased 14.49 11.15 12 810543 192 109778552
Physical deconditioning 14.45 11.15 4 810551 3533 109775211
Torticollis 14.42 11.15 3 810552 3218 109775526
Enuresis 14.36 11.15 6 810549 4090 109774654
Endocarditis 14.36 11.15 50 810505 13321 109765423
Alopecia universalis 14.35 11.15 16 810539 376 109778368
Malignant pleural effusion 14.34 11.15 6 810549 4087 109774657
Peripheral motor neuropathy 14.30 11.15 6 810549 4080 109774664
Vertebral osteophyte 14.30 11.15 19 810536 538 109778206
Spleen tuberculosis 14.29 11.15 7 810548 41 109778703
Goitre 14.28 11.15 86 810469 6118 109772626
Staphylococcal skin infection 14.26 11.15 38 810517 1847 109776897
Tendon rupture 14.26 11.15 162 810393 13916 109764828
Pancreatic duct stenosis 14.26 11.15 13 810542 238 109778506
Intestinal mucosal atrophy 14.26 11.15 6 810549 23 109778721
Callus formation delayed 14.26 11.15 6 810549 23 109778721
Cutaneous tuberculosis 14.23 11.15 14 810541 283 109778461
Rectal tube insertion 14.20 11.15 5 810550 10 109778734
Magnetic resonance imaging thoracic abnormal 14.20 11.15 5 810550 10 109778734
Type 1 diabetes mellitus 14.17 11.15 28 810527 9019 109769725
Hypoperfusion 14.16 11.15 3 810552 3178 109775566
Stomal hernia 14.14 11.15 19 810536 544 109778200
Ligament sprain 14.14 11.15 65 810490 16003 109762741
Grip strength 14.13 11.15 115 810440 9026 109769718
Regurgitation 14.13 11.15 4 810551 3481 109775263
Spinal osteoarthritis 14.08 11.15 217 810338 19966 109758778
Adverse food reaction 14.07 11.15 8 810547 66 109778678
Osteosclerosis 14.07 11.15 68 810487 4447 109774297
Phototherapy 14.06 11.15 6 810549 24 109778720
Muscle tightness 14.04 11.15 58 810497 14704 109764040
Medical device site joint infection 14.02 11.15 17 810538 438 109778306
Panic disorder 13.98 11.15 4 810551 3457 109775287
Abscess sterile 13.97 11.15 8 810547 67 109778677
Pneumonia pseudomonal 13.97 11.15 21 810534 7525 109771219
Lung adenocarcinoma stage IV 13.93 11.15 19 810536 552 109778192
Keratoacanthoma 13.93 11.15 32 810523 1416 109777328
Vasodilatation 13.93 11.15 5 810550 3739 109775005
Foreign body in gastrointestinal tract 13.92 11.15 10 810545 128 109778616
Blood sodium increased 13.89 11.15 12 810543 5511 109773233
Culture urine positive 13.89 11.15 9 810546 4787 109773957
White blood cells urine positive 13.87 11.15 21 810534 7503 109771241
Communication disorder 13.87 11.15 10 810545 5029 109773715
Aphonia 13.87 11.15 48 810507 12812 109765932
Clonal haematopoiesis 13.87 11.15 11 810544 165 109778579
Disinhibition 13.86 11.15 3 810552 3131 109775613
Squamous cell carcinoma 13.85 11.15 201 810354 18262 109760482
Lymphadenitis 13.85 11.15 78 810477 5415 109773329
Wound complication 13.82 11.15 85 810470 6092 109772652
Carotid artery occlusion 13.81 11.15 31 810524 9534 109769210
Rhonchi 13.75 11.15 8 810547 4510 109774234
Mean cell volume decreased 13.74 11.15 80 810475 5622 109773122
Angiolymphoid hyperplasia with eosinophilia 13.73 11.15 10 810545 131 109778613
Oropharyngeal discomfort 13.70 11.15 35 810520 10292 109768452
Sinus arrest 13.66 11.15 7 810548 4235 109774509
Bladder neoplasm 13.65 11.15 38 810517 1896 109776848
Gaze palsy 13.65 11.15 4 810551 3403 109775341
Anaphylactoid reaction 13.63 11.15 18 810537 6808 109771936
Cholelithiasis obstructive 13.63 11.15 7 810548 46 109778698
Middle insomnia 13.63 11.15 91 810464 20411 109758333
Injection site paraesthesia 13.62 11.15 22 810533 746 109777998
Necrotising enterocolitis neonatal 13.59 11.15 5 810550 12 109778732
Haemothorax 13.58 11.15 19 810536 7012 109771732
Rectal haemorrhage 13.56 11.15 1037 809518 118796 109659948
Injection site laceration 13.54 11.15 10 810545 134 109778610
Eye infection staphylococcal 13.51 11.15 12 810543 212 109778532
Breath sounds abnormal 13.48 11.15 120 810435 25284 109753460
Testicular germ cell cancer 13.48 11.15 4 810551 3 109778741
Mononucleosis heterophile test positive 13.48 11.15 4 810551 3 109778741
PASH syndrome 13.48 11.15 4 810551 3 109778741
Ischaemia 13.48 11.15 29 810526 9054 109769690
Abortion incomplete 13.47 11.15 3 810552 3069 109775675
Precancerous skin lesion 13.45 11.15 34 810521 1600 109777144
Chronic inflammatory demyelinating polyradiculoneuropathy 13.44 11.15 41 810514 2154 109776590
Eye inflammation 13.44 11.15 114 810441 9057 109769687
Vulval abscess 13.42 11.15 24 810531 885 109777859
Ovarian adenoma 13.42 11.15 12 810543 214 109778530
Torus fracture 13.42 11.15 10 810545 136 109778608
Multiple system atrophy 13.40 11.15 15 810540 354 109778390
Speech sound disorder 13.38 11.15 7 810548 48 109778696
Dolichocolon 13.38 11.15 7 810548 48 109778696
Diabetic eye disease 13.37 11.15 12 810543 215 109778529
Vaginal haematoma 13.36 11.15 10 810545 137 109778607
Hereditary motor and sensory neuropathy 13.36 11.15 10 810545 137 109778607
Muscle contractions involuntary 13.34 11.15 8 810547 4436 109774308
Rectal dysplasia 13.34 11.15 6 810549 28 109778716
Sigmoidectomy 13.31 11.15 8 810547 74 109778670
Medical device site inflammation 13.31 11.15 5 810550 13 109778731
Macular degeneration 13.29 11.15 228 810327 21431 109757313
Insurance issue 13.29 11.15 37 810518 10575 109768169
Cardiolipin antibody positive 13.28 11.15 11 810544 176 109778568
Mean cell haemoglobin decreased 13.19 11.15 94 810461 7080 109771664
Application site pruritus 13.19 11.15 7 810548 4153 109774591
Abortion 13.19 11.15 34 810521 1620 109777124
Oesophageal candidiasis 13.16 11.15 42 810513 11492 109767252
Acquired claw toe 13.15 11.15 7 810548 50 109778694
Application site erythema 13.15 11.15 13 810542 5597 109773147
Chronic idiopathic pain syndrome 13.15 11.15 12 810543 220 109778524
Right ventricular dysfunction 13.13 11.15 4 810551 3319 109775425
Lower respiratory tract inflammation 13.13 11.15 11 810544 179 109778565
Vasculitis necrotising 13.10 11.15 33 810522 1550 109777194
Tetany 13.09 11.15 5 810550 3599 109775145
Ischaemic hepatitis 13.09 11.15 9 810546 4639 109774105
Breast abscess 13.08 11.15 35 810520 1706 109777038
Metastases to meninges 13.07 11.15 11 810544 5117 109773627
Hyperglycaemic hyperosmolar nonketotic syndrome 13.07 11.15 3 810552 3006 109775738
Bone swelling 13.07 11.15 36 810519 1785 109776959
Enterococcal sepsis 13.06 11.15 4 810551 3308 109775436
Ganglioneuroma 13.06 11.15 10 810545 142 109778602
Venous injury 13.04 11.15 25 810530 973 109777771
Cutaneous T-cell lymphoma stage II 13.03 11.15 7 810548 51 109778693
Steatohepatitis 13.03 11.15 29 810526 1256 109777488
Mechanical ventilation 13.03 11.15 4 810551 3303 109775441
Monoclonal gammopathy 13.03 11.15 28 810527 1184 109777560
Malignant melanoma in situ 13.01 11.15 56 810499 3486 109775258
Eczema infected 12.98 11.15 11 810544 182 109778562
Intervertebral disc operation 12.97 11.15 26 810529 1046 109777698
Perfusion brain scan abnormal 12.95 11.15 4 810551 4 109778740
Eosinophil morphology abnormal 12.95 11.15 4 810551 4 109778740
Wound infection pseudomonas 12.91 11.15 43 810512 2368 109776376
Language disorder 12.86 11.15 6 810549 3832 109774912
Pemphigoid 12.84 11.15 88 810467 19619 109759125
Trigeminal neuralgia 12.83 11.15 8 810547 4344 109774400
Aphthous ulcer 12.79 11.15 222 810333 20914 109757830
Gastrointestinal dilation procedure 12.79 11.15 5 810550 15 109778729
Collagen-vascular disease 12.79 11.15 8 810547 80 109778664
Streptococcal infection 12.75 11.15 129 810426 10761 109767983
Dilatation ventricular 12.71 11.15 7 810548 4068 109774676
Exposed bone in jaw 12.71 11.15 6 810549 3805 109774939
Pharyngeal neoplasm 12.70 11.15 6 810549 32 109778712
Injection site oedema 12.66 11.15 36 810519 1818 109776926
Lipoma 12.64 11.15 60 810495 3895 109774849
Tongue biting 12.63 11.15 3 810552 2936 109775808
Terminal insomnia 12.63 11.15 37 810518 1901 109776843
Metastasis 12.60 11.15 26 810529 8241 109770503
Deafness 12.58 11.15 270 810285 26439 109752305
Anal cancer 12.58 11.15 22 810533 797 109777947
Erythema elevatum diutinum 12.56 11.15 5 810550 16 109778728
HLA-B*27 positive 12.55 11.15 10 810545 151 109778593
Hepatotoxicity 12.55 11.15 361 810194 63039 109715705
Dermatitis contact 12.54 11.15 56 810499 13897 109764847
Eosinophilic pneumonia 12.54 11.15 21 810534 7206 109771538
Uterine cyst 12.52 11.15 14 810541 330 109778414
Steroid diabetes 12.52 11.15 12 810543 5242 109773502
Drain removal 12.49 11.15 4 810551 5 109778739
Benign hepatic neoplasm 12.46 11.15 8 810547 84 109778660
Suicidal behaviour 12.46 11.15 5 810550 3492 109775252
Overlap syndrome 12.44 11.15 111 810444 8948 109769796
Metatarsalgia 12.42 11.15 15 810540 385 109778359
Polyserositis 12.42 11.15 25 810530 1009 109777735
Acute pulmonary histoplasmosis 12.41 11.15 13 810542 284 109778460
Atypical fibroxanthoma 12.40 11.15 11 810544 194 109778550
Reversible cerebral vasoconstriction syndrome 12.40 11.15 10 810545 4751 109773993
Genital cyst 12.39 11.15 7 810548 57 109778687
Inguinal hernia 12.39 11.15 98 810457 7627 109771117
SLE arthritis 12.34 11.15 19 810536 618 109778126
Pityriasis 12.33 11.15 5 810550 17 109778727
Incision site pruritus 12.27 11.15 6 810549 35 109778709
Benign neoplasm 12.26 11.15 27 810528 1161 109777583
Allergic respiratory symptom 12.23 11.15 10 810545 157 109778587
Tuberculosis of eye 12.23 11.15 8 810547 87 109778657
Gastritis haemorrhagic 12.22 11.15 4 810551 3169 109775575
Tuberculous pleurisy 12.21 11.15 20 810535 686 109778058
Vaginal haemorrhage 12.21 11.15 121 810434 24953 109753791
Clostridium test positive 12.20 11.15 40 810515 10853 109767891
Skin neoplasm excision 12.20 11.15 38 810517 2020 109776724
Bicytopenia 12.17 11.15 19 810536 6705 109772039
Cartilage injury 12.17 11.15 33 810522 1621 109777123
Hepatic enzyme 12.16 11.15 72 810483 5091 109773653
Computerised tomogram abdomen abnormal 12.15 11.15 8 810547 88 109778656
Poor quality device used 12.15 11.15 3 810552 2860 109775884
Dermatopathic lymphadenopathy 12.13 11.15 6 810549 36 109778708
Limb fracture 12.13 11.15 6 810549 36 109778708
Infected dermal cyst 12.11 11.15 29 810526 1319 109777425
Human anti-human antibody test 12.09 11.15 15 810540 396 109778348
Immune reconstitution inflammatory syndrome associated tuberculosis 12.09 11.15 25 810530 1029 109777715
Activated partial thromboplastin time ratio increased 12.07 11.15 4 810551 6 109778738
Ocular hypertension 12.06 11.15 42 810513 2366 109776378
Laryngeal cancer 12.06 11.15 21 810534 758 109777986
Granulomatous liver disease 12.05 11.15 32 810523 1552 109777192
Q fever 12.05 11.15 13 810542 294 109778450
Sinus disorder 12.05 11.15 168 810387 32560 109746184
Cardiac amyloidosis 11.99 11.15 3 810552 2834 109775910
Rehabilitation therapy 11.98 11.15 39 810516 2122 109776622
Testicular seminoma (pure) 11.97 11.15 10 810545 162 109778582
Product residue present 11.96 11.15 7 810548 3934 109774810
Subclavian vein thrombosis 11.95 11.15 3 810552 2829 109775915
Genital hypoaesthesia 11.95 11.15 11 810544 204 109778540
Follicular thyroid cancer 11.93 11.15 8 810547 91 109778653
Skin discolouration 11.92 11.15 271 810284 48775 109729969
Mucosal erosion 11.90 11.15 3 810552 2821 109775923
Bone density increased 11.88 11.15 24 810531 971 109777773
Akinesia 11.88 11.15 6 810549 3661 109775083
Oesophageal spasm 11.87 11.15 6 810549 3660 109775084
Decreased immune responsiveness 11.83 11.15 115 810440 9491 109769253
Ovarian cancer metastatic 11.83 11.15 21 810534 770 109777974
Oesophageal carcinoma 11.77 11.15 44 810511 11480 109767264
Dirofilariasis 11.77 11.15 3 810552 0 109778744
Mammary fistula 11.77 11.15 3 810552 0 109778744
Benign neoplasm of prostate 11.77 11.15 3 810552 0 109778744
Reticular erythematous mucinosis 11.77 11.15 3 810552 0 109778744
Adenosine deaminase increased 11.77 11.15 3 810552 0 109778744
Gastroenteritis shigella 11.77 11.15 3 810552 0 109778744
Gastrointestinal anastomotic complication 11.77 11.15 3 810552 0 109778744
Testicular germ cell tumour 11.77 11.15 3 810552 0 109778744
Neoplasm of orbit 11.77 11.15 3 810552 0 109778744
Orbital granuloma 11.77 11.15 3 810552 0 109778744
Intervertebral disc calcification 11.77 11.15 3 810552 0 109778744
Appendiceal mucocoele 11.77 11.15 3 810552 0 109778744
Magnetic resonance imaging abdominal abnormal 11.77 11.15 3 810552 0 109778744
Meningitis leptospiral 11.77 11.15 3 810552 0 109778744
Prothrombin time shortened 11.76 11.15 6 810549 3640 109775104
Meningioma benign 11.74 11.15 13 810542 303 109778441
Panic reaction 11.72 11.15 13 810542 5309 109773435
Ear injury 11.72 11.15 14 810541 355 109778389
False positive tuberculosis test 11.72 11.15 5 810550 20 109778724
Pleomorphic adenoma 11.72 11.15 5 810550 20 109778724
Focal segmental glomerulosclerosis 11.71 11.15 8 810547 4137 109774607
Fallopian tube operation 11.70 11.15 4 810551 7 109778737
Mastoidectomy 11.70 11.15 4 810551 7 109778737
Bowel movement irregularity 11.64 11.15 96 810459 7564 109771180
Ototoxicity 11.63 11.15 8 810547 4123 109774621
Tonic convulsion 11.62 11.15 4 810551 3070 109775674
High density lipoprotein decreased 11.57 11.15 15 810540 5718 109773026
Thyroid operation 11.57 11.15 11 810544 213 109778531
Muscle fatigue 11.53 11.15 59 810496 3948 109774796
Anastomotic complication 11.52 11.15 18 810537 593 109778151
Multifocal motor neuropathy 11.51 11.15 9 810546 132 109778612
Skin graft infection 11.50 11.15 8 810547 97 109778647
Tendon sheath incision 11.49 11.15 6 810549 41 109778703
Benign salivary gland neoplasm 11.49 11.15 6 810549 41 109778703
Tearfulness 11.49 11.15 23 810532 7372 109771372
Organ failure 11.48 11.15 11 810544 4806 109773938
Rectal cancer metastatic 11.47 11.15 17 810538 534 109778210
Dilatation atrial 11.47 11.15 7 810548 3845 109774899
Vulvovaginal dryness 11.42 11.15 3 810552 2744 109776000
Colorectal cancer stage IV 11.42 11.15 4 810551 3037 109775707
Oral surgery 11.42 11.15 30 810525 1446 109777298
Butterfly rash 11.41 11.15 38 810517 2093 109776651
Haemorrhagic transformation stroke 11.39 11.15 4 810551 3033 109775711
Ileal perforation 11.39 11.15 29 810526 1371 109777373
Squamous cell carcinoma of the tongue 11.38 11.15 21 810534 794 109777950
Hypophagia 11.36 11.15 296 810259 52330 109726414
Device breakage 11.36 11.15 57 810498 13712 109765032
Rash erythematous 11.35 11.15 487 810068 81345 109697399
Neoplasm prostate 11.34 11.15 10 810545 175 109778569
Escherichia sepsis 11.31 11.15 38 810517 10234 109768510
Colon operation 11.29 11.15 17 810538 542 109778202
Idiopathic pulmonary fibrosis 11.27 11.15 12 810543 4992 109773752
Lymphoproliferative disorder 11.26 11.15 91 810464 7127 109771617
Swollen joint count 11.26 11.15 105 810450 8569 109770175
Sinusitis fungal 11.25 11.15 3 810552 2717 109776027
Pulmonary function test abnormal 11.25 11.15 12 810543 4988 109773756
Thyroid neoplasm 11.23 11.15 51 810504 3250 109775494
Pharyngeal oedema 11.22 11.15 176 810379 16252 109762492
Meningitis cryptococcal 11.20 11.15 11 810544 4751 109773993
Product use complaint 11.20 11.15 7 810548 3796 109774948
Injection site plaque 11.20 11.15 10 810545 178 109778566
Renal amyloidosis 11.19 11.15 13 810542 320 109778424
Rash vesicular 11.18 11.15 160 810395 14492 109764252
Abdominal pain upper 11.16 11.15 2801 807754 346310 109432434

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L04AB04 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
IMMUNOSUPPRESSANTS
IMMUNOSUPPRESSANTS
Tumor necrosis factor alpha (TNF-alpha) inhibitors
FDA CS M0001357 Antibodies, Monoclonal
FDA MoA N0000175451 Tumor Necrosis Factor Receptor Blocking Activity
MeSH PA D000079424 Tumor Necrosis Factor Inhibitors
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D018501 Antirheumatic Agents
FDA EPC N0000175610 Tumor Necrosis Factor Blocker
CHEBI has role CHEBI:22587 antiviral agent
CHEBI has role CHEBI:35480 analgesic
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:35842 antirheumatic drug
CHEBI has role CHEBI:50748 antipsoriatic
CHEBI has role CHEBI:65023 anti-asthmatic agent
CHEBI has role CHEBI:66981 ophthalmology drug
CHEBI has role CHEBI:67079 anti-inflammatory agent

Related Drugs by ATC class:

L04AB Tumor necrosis factor alpha (TNF-alpha) inhibitors 4 drugs
certolizumab pegoletanerceptgolimumabinfliximab

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Ankylosing spondylitis indication 9631008 DOID:7147
Psoriasis with arthropathy indication 33339001
Crohn's disease indication 34000006
Hidradenitis suppurativa indication 59393003 DOID:2280
Ulcerative colitis indication 64766004 DOID:8577
Rheumatoid arthritis indication 69896004 DOID:7148
Pyoderma gangrenosum indication 74578003 DOID:8553
Psoriatic arthritis indication 156370009 DOID:9008
Plaque psoriasis indication 200965009
Pustular psoriasis indication 200973000
Non-infectious anterior uveitis indication 267619000
Behcet's disease indication 310701003 DOID:13241
Juvenile idiopathic arthritis indication 410502007
Axial spondyloarthritis indication 723116002
Non-infectious intermediate, posterior and panuveitis indication 733337008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Tumor necrosis factor Cytokine ANTIBODY BINDING DRUG LABEL DRUG LABEL

External reference:

IDSource
FYS6T7F842 UNII
D02597 KEGG_DRUG
4021370 VUID
N0000148789 NUI
4021370 VANDF
4042009 VANDF
4042360 VANDF
C1122087 UMLSCUI
CHEBI:749494 CHEBI
CHEMBL1201580 ChEMBL_ID
DB00051 DRUGBANK_ID
D000068879 MESH_DESCRIPTOR_UI
7860 INN_ID
4860 IUPHAR_LIGAND_ID
2103477 RXNORM
17071 MMSL
248487 MMSL
33375 MMSL
33385 MMSL
368840 MMSL
45825 MMSL
d04835 MMSL
009871 NDDF
016993 NDDF
017321 NDDF
398728003 SNOMEDCT_US
407317001 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ABRILADA HUMAN PRESCRIPTION DRUG LABEL 1 0025-0319 INJECTION, SOLUTION 40 mg SUBCUTANEOUS BLA 34 sections
HADLIMA HUMAN PRESCRIPTION DRUG LABEL 1 50090-6704 SOLUTION 40 mg SUBCUTANEOUS BLA 31 sections
HADLIMA HUMAN PRESCRIPTION DRUG LABEL 1 50090-6705 SOLUTION 40 mg SUBCUTANEOUS BLA 31 sections
HADLIMA HUMAN PRESCRIPTION DRUG LABEL 1 50090-6706 SOLUTION 40 mg SUBCUTANEOUS BLA 31 sections
HADLIMA HUMAN PRESCRIPTION DRUG LABEL 1 50090-6707 SOLUTION 40 mg SUBCUTANEOUS BLA 31 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-399 INJECTION 20 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-399 INJECTION 20 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-400 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-400 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-410 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-410 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-411 INJECTION 20 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-411 INJECTION 20 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-413 INJECTION 10 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-413 INJECTION 10 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-479 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-479 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-480 INJECTION 80 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-480 INJECTION 80 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-481 INJECTION 80 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-481 INJECTION 80 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-482 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
AMJEVITA HUMAN PRESCRIPTION DRUG LABEL 1 55513-482 INJECTION 40 mg SUBCUTANEOUS BLA 34 sections
Adalimumab HUMAN PRESCRIPTION DRUG LABEL 1 61314-325 INJECTION, SOLUTION 80 mg SUBCUTANEOUS BLA 30 sections
Adalimumab HUMAN PRESCRIPTION DRUG LABEL 1 61314-325 INJECTION, SOLUTION 80 mg SUBCUTANEOUS BLA 30 sections
Adalimumab HUMAN PRESCRIPTION DRUG LABEL 1 61314-327 INJECTION, SOLUTION 40 mg SUBCUTANEOUS BLA 30 sections
Adalimumab HUMAN PRESCRIPTION DRUG LABEL 1 61314-327 INJECTION, SOLUTION 40 mg SUBCUTANEOUS BLA 30 sections
Adalimumab HUMAN PRESCRIPTION DRUG LABEL 1 61314-332 INJECTION, SOLUTION 20 mg SUBCUTANEOUS BLA 30 sections
Adalimumab HUMAN PRESCRIPTION DRUG LABEL 1 61314-332 INJECTION, SOLUTION 20 mg SUBCUTANEOUS BLA 30 sections
Adalimumab HUMAN PRESCRIPTION DRUG LABEL 1 61314-391 INJECTION, SOLUTION 10 mg SUBCUTANEOUS BLA 30 sections