calcium polystyrene sulfonate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4871 37286-92-3

Description:

MoleculeDescription

Synonyms:

  • calcium polystyrene sulfonate
  • calcium polystyrene sulphonate
  • calcium polystyrenesulfonate
  • kalimate
  • Molecular weight:
  • Formula: (C16H14CaO6S2)n
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
45 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hyperkalaemia 127.42 32.95 44 988 50821 56240214
Renal impairment 65.21 32.95 31 1001 80682 56210353
Cardiac failure 38.72 32.95 22 1010 82071 56208964

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hyperkalaemia 146.82 29.06 72 1748 64279 31631245
Crystal deposit intestine 72.07 29.06 11 1809 90 31695434
Renal impairment 46.72 29.06 39 1781 86310 31609214

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hyperkalaemia 257.38 27.38 114 2979 106477 70818874
Renal impairment 100.92 27.38 68 3025 143869 70781482
Crystal deposit intestine 73.78 27.38 12 3081 205 70925146
Shunt stenosis 57.62 27.38 13 3080 1299 70924052
Cardiac failure 54.28 27.38 47 3046 143494 70781857
Hepatic function abnormal 44.85 27.38 31 3062 67965 70857386
Anaemia 40.59 27.38 67 3026 403356 70521995
Chronic kidney disease 38.31 27.38 27 3066 61030 70864321
Interstitial lung disease 35.00 27.38 32 3061 104653 70820698
Shunt occlusion 30.99 27.38 8 3085 1407 70923944
Acute kidney injury 30.40 27.38 65 3028 474559 70450792

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V03AE01 VARIOUS
ALL OTHER THERAPEUTIC PRODUCTS
ALL OTHER THERAPEUTIC PRODUCTS
Drugs for treatment of hyperkalemia and hyperphosphatemia
MeSH PA D002411 Cation Exchange Resins
MeSH PA D002614 Chelating Agents
MeSH PA D007475 Ion Exchange Resins
MeSH PA D064449 Sequestering Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hyperkalemia indication 14140009




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
HUI2S00793 UNII
D03270 KEGG_DRUG
C0108139 UMLSCUI
CHEBI:53277 CHEBI
CHEMBL2109033 ChEMBL_ID
169893 PUBCHEM_CID
C003321 MESH_SUPPLEMENTAL_RECORD_UI
DB01344 DRUGBANK_ID
1546437 RXNORM
003509 NDDF
006664 NDDF
1002242008 SNOMEDCT_US
395788004 SNOMEDCT_US
710808009 SNOMEDCT_US
C0137904 UMLSCUI
CHEMBL1201484 ChEMBL_ID
8324 INN_ID
28210-41-5 SECONDARY_CAS_RN
75905 PUBCHEM_CID
ZSL2FB6GXN UNII

Pharmaceutical products:

None