calcium polystyrene sulfonate Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4871 37286-92-3

Description:

MoleculeDescription

Synonyms:

  • calcium polystyrene sulfonate
  • calcium polystyrene sulphonate
  • calcium polystyrenesulfonate
  • kalimate
  • Molecular weight:
  • Formula: (C16H14CaO6S2)n
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
45 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hyperkalaemia 149.34 31.67 55 1236 50654 46634117
Renal impairment 50.08 31.67 29 1262 74343 46610428
Cardiac failure 48.14 31.67 29 1262 79919 46604852
Hepatic function abnormal 42.00 31.67 20 1271 34401 46650370

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hyperkalaemia 129.20 27.27 73 2181 65937 29884287
Renal impairment 66.41 27.27 53 2201 84131 29866093
Hepatic function abnormal 40.87 27.27 30 2224 41915 29908309
Blood potassium increased 29.06 27.27 17 2237 16196 29934028
Blood creatinine increased 29.01 27.27 35 2219 91340 29858884

Pharmacologic Action:

SourceCodeDescription
ATC V03AE01 VARIOUS
ALL OTHER THERAPEUTIC PRODUCTS
ALL OTHER THERAPEUTIC PRODUCTS
Drugs for treatment of hyperkalemia and hyperphosphatemia
MeSH PA D002411 Cation Exchange Resins
MeSH PA D002614 Chelating Agents
MeSH PA D007475 Ion Exchange Resins
MeSH PA D064449 Sequestering Agents

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Hyperkalemia indication 14140009

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D03270 KEGG_DRUG
28210-41-5 SECONDARY_CAS_RN
C0108139 UMLSCUI
C0032604 UMLSCUI
CHEBI:53276 CHEBI
CHEMBL2109033 ChEMBL_ID
CHEMBL1201484 ChEMBL_ID
C003321 MESH_SUPPLEMENTAL_RECORD_UI
169893 PUBCHEM_CID
8324 INN_ID
HUI2S00793 UNII
7501 PUBCHEM_CID
DB01344 DRUGBANK_ID
ZSL2FB6GXN UNII
1546437 RXNORM
003509 NDDF
006664 NDDF
1002242008 SNOMEDCT_US
395788004 SNOMEDCT_US
710808009 SNOMEDCT_US

Pharmaceutical products:

None