laninamivir octanoate hydrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antivirals neuraminidase inhibitors | 4822 | 203120-46-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
an antiviral agent
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 40 | mg | Inhal.powder |
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Sept. 10, 2010 | PMDA | Daiichi Sankyo Company, Limited |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J05AH04 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIVIRALS FOR SYSTEMIC USE DIRECT ACTING ANTIVIRALS Neuraminidase inhibitors |
| MeSH PA | D000890 | Anti-Infective Agents |
| MeSH PA | D000998 | Antiviral Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Influenza | indication | 6142004 | DOID:8469 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 2.71 | acidic |
| pKa2 | 13.69 | acidic |
| pKa3 | 9.82 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Neuraminidase | Enzyme | IC50 | 8.89 | CHEMBL | |||||
| Neuraminidase | Enzyme | IC50 | 5.51 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D09547 | KEGG_DRUG |
| C4706204 | UMLSCUI |
| CHEBI:134741 | CHEBI |
| LVO | PDB_CHEM_ID |
| LNV | PDB_CHEM_ID |
| 9847629 | PUBCHEM_CID |
| CHEMBL467058 | ChEMBL_ID |
| C546918 | MESH_SUPPLEMENTAL_RECORD_UI |
| C546919 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB11888 | DRUGBANK_ID |
| DB12791 | DRUGBANK_ID |
| C2931958 | UMLSCUI |
| CHEMBL466246 | ChEMBL_ID |
| 9047 | INN_ID |
| 203120-17-6 | SECONDARY_CAS_RN |
| 502272 | PUBCHEM_CID |
| E026V904RL | UNII |
| B408IW3GL5 | UNII |
Pharmaceutical products:
None