Molfile
Inchi
Smiles
Synonyms:
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bedaquiline
-
sirturo
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TMC207
-
bedaquiline fumarate
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Bedaquiline is a diarylquinoline antimycobacterial drug that inhibits mycobacterial ATP (adenosine 5'-triphosphate) synthase, by binding to subunit c of the enzyme that is essential for the generation of energy in M. tuberculosis.
- Molecular weight: 555.52
- Formula: C32H31BrN2O2
- CLOGP: 7.25
- LIPINSKI: 2
- HAC: 4
- HDO: 1
- TPSA: 45.59
- ALOGS: -6.46
- ROTB: 8
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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