Stem definition | Drug id | CAS RN |
---|---|---|
470 | 76-22-2 |
Dose | Unit | Route |
---|---|---|
0.15 | g | O |
None
Date | Agency | Company | Orphan |
---|---|---|---|
None | FDA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Methaemoglobinaemia | 222.50 | 18.87 | 43 | 2202 | 1999 | 50600880 |
Cyanosis | 35.41 | 18.87 | 16 | 2229 | 15168 | 50587711 |
Drug hypersensitivity | 35.06 | 18.87 | 49 | 2196 | 250961 | 50351918 |
Nail bed tenderness | 30.14 | 18.87 | 6 | 2239 | 323 | 50602556 |
Dermatitis atopic | 23.52 | 18.87 | 8 | 2237 | 3578 | 50599301 |
Autonomic neuropathy | 23.42 | 18.87 | 6 | 2239 | 1007 | 50601872 |
Anxiety disorder | 23.33 | 18.87 | 8 | 2237 | 3665 | 50599214 |
Vulvovaginal swelling | 22.75 | 18.87 | 5 | 2240 | 435 | 50602444 |
Vitamin D deficiency | 20.37 | 18.87 | 10 | 2235 | 11392 | 50591487 |
Skin discolouration | 19.20 | 18.87 | 14 | 2231 | 32743 | 50570136 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Methaemoglobinaemia | 119.42 | 24.60 | 26 | 1063 | 2645 | 29570793 |
Erythema multiforme | 25.94 | 24.60 | 10 | 1079 | 7707 | 29565731 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Methaemoglobinaemia | 319.65 | 18.26 | 66 | 2814 | 4282 | 64491570 |
Cyanosis | 41.18 | 18.26 | 20 | 2860 | 22135 | 64473717 |
Nail bed tenderness | 30.01 | 18.26 | 6 | 2874 | 328 | 64495524 |
Pruritus | 24.23 | 18.26 | 47 | 2833 | 312353 | 64183499 |
Vulvovaginal swelling | 24.23 | 18.26 | 5 | 2875 | 320 | 64495532 |
Drug hypersensitivity | 22.50 | 18.26 | 39 | 2841 | 237776 | 64258076 |
Autonomic neuropathy | 20.47 | 18.26 | 6 | 2874 | 1646 | 64494206 |
Skin discolouration | 20.42 | 18.26 | 15 | 2865 | 35240 | 64460612 |
None
Source | Code | Description |
---|---|---|
ATC | C01EB02 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY OTHER CARDIAC PREPARATIONS Other cardiac preparations |
MeSH PA | D000890 | Anti-Infective Agents |
MeSH PA | D000891 | Anti-Infective Agents, Local |
CHEBI has role | CHEBI:25212 | metabolites |
CHEBI has role | CHEBI:27311 | essential oil component |
CHEBI has role | CHEBI:76924 | plant metabolites |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Backache | indication | 161891005 | |
Sprains and Strains | indication | ||
Arthritic Pain | indication | ||
Gastritis | contraindication | 4556007 | DOID:4029 |
Infection of skin AND/OR subcutaneous tissue | contraindication | 19824006 | |
Gastrointestinal ulcer | contraindication | 40845000 | |
Body fluid retention | contraindication | 43498006 | |
Disorder of cardiovascular system | contraindication | 49601007 | DOID:1287 |
Vitamin K deficiency | contraindication | 52675005 | DOID:11249 |
Nasal polyp | contraindication | 52756005 | |
Hepatic failure | contraindication | 59927004 | |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Factor II deficiency | contraindication | 73975000 | |
Gastrointestinal hemorrhage | contraindication | 74474003 | |
Thrombotic thrombocytopenic purpura | contraindication | 78129009 | DOID:10772 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Thyrotoxicosis | contraindication | 90739004 | DOID:7997 |
Hemophilia | contraindication | 90935002 | |
Disorder of skin | contraindication | 95320005 | DOID:37 |
Anemia due to enzyme deficiency | contraindication | 111577008 | |
Gastroesophageal reflux disease | contraindication | 235595009 | DOID:8534 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Condyloma acuminatum | contraindication | 240542006 | DOID:11168 |
Anemia | contraindication | 271737000 | DOID:2355 |
Pregnancy, function | contraindication | 289908002 | |
Skin irritation | contraindication | 367466007 | |
Cardiovascular event risk | contraindication | 395112001 | |
Peripheral vascular disease | contraindication | 400047006 | |
Breastfeeding (mother) | contraindication | 413712001 | |
Blister | contraindication | 417237009 | |
Denuded skin | contraindication | 418242004 | |
Inflammatory dermatosis | contraindication | 703938007 |
None
None
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase | Enzyme | Ki | 4.30 | CHEMBL | |||||
Transient receptor potential cation channel subfamily A member 1 | Ion channel | GATING INHIBITOR | IC50 | 4.20 | IUPHAR |
ID | Source |
---|---|
4017533 | VUID |
N0000145916 | NUI |
D00098 | KEGG_DRUG |
464-49-3 | SECONDARY_CAS_RN |
1298738 | RXNORM |
C0006809 | UMLSCUI |
CHEBI:36773 | CHEBI |
CAM | PDB_CHEM_ID |
CHEMBL504760 | ChEMBL_ID |
DB01744 | DRUGBANK_ID |
D002164 | MESH_DESCRIPTOR_UI |
2537 | PUBCHEM_CID |
2422 | IUPHAR_LIGAND_ID |
C436264 | MESH_SUPPLEMENTAL_RECORD_UI |
DB11288 | DRUGBANK_ID |
DB14156 | DRUGBANK_ID |
4343 | MMSL |
6005 | MMSL |
001385 | NDDF |
001993 | NDDF |
005178 | NDDF |
006104 | NDDF |
111136003 | SNOMEDCT_US |
412108007 | SNOMEDCT_US |
46137002 | SNOMEDCT_US |
4017533 | VANDF |
5TJD82A1ET | UNII |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Major Camphor and Phenol | HUMAN OTC DRUG LABEL | 2 | 00904-7851 | LIQUID | 10.80 g | TOPICAL | OTC monograph final | 12 sections |
AleveX | HUMAN OTC DRUG LABEL | 2 | 0280-0049 | SPRAY | 5.50 mg | TOPICAL | OTC monograph not final | 15 sections |
AleveX | HUMAN OTC DRUG LABEL | 2 | 0280-0050 | LOTION | 5.50 mg | TOPICAL | OTC monograph not final | 15 sections |
AleveX | HUMAN OTC DRUG LABEL | 2 | 0280-0063 | LOTION | 5.50 mg | TOPICAL | OTC monograph not final | 14 sections |
Sarna | HUMAN OTC DRUG LABEL | 2 | 0316-0229 | LOTION | 5 mg | TOPICAL | OTC monograph not final | 13 sections |
Vaporizing | HUMAN OTC DRUG LABEL | 1 | 0363-0055 | INHALANT | 62 mg | RESPIRATORY (INHALATION) | OTC monograph final | 15 sections |
WALGREENS MEDICATED PAIN RELIEVING | HUMAN OTC DRUG LABEL | 3 | 0363-0149 | PATCH | 7.10 mg | TOPICAL | OTC monograph not final | 14 sections |
Walgreens Cold Sore Treatment | HUMAN OTC DRUG LABEL | 2 | 0363-0407 | CREAM | 30 mg | TOPICAL | OTC monograph not final | 10 sections |
Walgreens Cold Sore Treatment | HUMAN OTC DRUG LABEL | 2 | 0363-0407 | CREAM | 30 mg | TOPICAL | OTC monograph not final | 10 sections |
Pain Relief Patches | HUMAN OTC DRUG LABEL | 3 | 0363-0907 | PATCH | 3.10 g | TOPICAL | OTC monograph not final | 11 sections |
Walgreens Chest Rub | HUMAN OTC DRUG LABEL | 3 | 0363-1001 | OINTMENT | 48 mg | TOPICAL | OTC monograph final | 12 sections |
Walgreens Chest Rub | HUMAN OTC DRUG LABEL | 3 | 0363-1001 | OINTMENT | 48 mg | TOPICAL | OTC monograph final | 12 sections |
Walgreens Pain Relieving Analgesic | HUMAN OTC DRUG LABEL | 3 | 0363-1199 | CREAM | 40 mg | TOPICAL | OTC MONOGRAPH NOT FINAL | 15 sections |
No Touch Application Chest RubWell at Walgreens | HUMAN OTC DRUG LABEL | 3 | 0363-3267 | STICK | 4.80 g | TOPICAL | OTC monograph final | 7 sections |
Walgreen Anti Itch | HUMAN OTC DRUG LABEL | 2 | 0363-4262 | LOTION | 0.50 g | TOPICAL | OTC monograph not final | 12 sections |
Medicated Lip Balm | HUMAN OTC DRUG LABEL | 3 | 0363-6040 | SALVE | 1.70 mg | TOPICAL | OTC monograph not final | 9 sections |
Medicated Lip Balm | HUMAN OTC DRUG LABEL | 3 | 0363-6080 | STICK | 1.70 mg | TOPICAL | OTC monograph not final | 9 sections |
Chest Rub | HUMAN OTC DRUG LABEL | 3 | 0363-8480 | LOTION | 4.80 kg | TOPICAL | OTC monograph final | 15 sections |
Walgreens Camphor Phenol Gel | HUMAN OTC DRUG LABEL | 2 | 0363-9425 | GEL | 10.80 mg | TOPICAL | OTC monograph not final | 8 sections |
Pain Relieving Patches | HUMAN OTC DRUG LABEL | 3 | 0363-9903 | PATCH | 1.20 1 | TOPICAL | OTC monograph not final | 12 sections |
Large Pain Relieving | HUMAN OTC DRUG LABEL | 3 | 0363-9904 | PATCH | 3.10 g | TOPICAL | OTC monograph not final | 13 sections |
HUMCO Camphor Spirit | HUMAN OTC DRUG LABEL | 1 | 0395-0467 | LIQUID | 100 mg | TOPICAL | OTC monograph not final | 13 sections |
HUMCO Camphor Spirit | HUMAN OTC DRUG LABEL | 1 | 0395-0467 | LIQUID | 100 mg | TOPICAL | OTC monograph not final | 13 sections |
Camphor Spirit | HUMAN OTC DRUG LABEL | 1 | 0395-9112 | LIQUID | 100 mg | TOPICAL | OTC monograph not final | 12 sections |
Rugby Anti-Itch | HUMAN OTC DRUG LABEL | 2 | 0536-1268 | LOTION | 0.50 g | TOPICAL | OTC monograph not final | 11 sections |
ANBESOL COLD SORE THERAPY | HUMAN OTC DRUG LABEL | 4 | 0573-0246 | OINTMENT | 30 mg | TOPICAL | OTC monograph not final | 14 sections |
CHAPSTICK MEDICATED | HUMAN OTC DRUG LABEL | 4 | 0573-0720 | STICK | 10 mg | TOPICAL | OTC monograph not final | 13 sections |
CHAPSTICK CLASSIC MEDICATED | HUMAN OTC DRUG LABEL | 3 | 0573-2031 | STICK | 16 mg | TOPICAL | OTC monograph not final | 13 sections |
Chest Rub | HUMAN OTC DRUG LABEL | 3 | 0869-0248 | CREAM | 4.80 kg | TOPICAL | OTC monograph final | 16 sections |
Chest Rub | HUMAN OTC DRUG LABEL | 3 | 0869-0248 | CREAM | 4.80 kg | TOPICAL | OTC monograph final | 16 sections |