ornipressin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
vasoconstrictors, vasopressin derivatives 4679 3397-23-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ornipressin
  • ornithine-vasopressin
  • orpressin
A synthetic analog of vasopressin with ORNITHINE substitution at residue 8 of the cyclic nonapeptide. It is used as a local vasoconstrictor and hemostatic.
  • Molecular weight: 1042.20
  • Formula: C45H63N13O12S2
  • CLOGP: -2.27
  • LIPINSKI: 3
  • HAC: 25
  • HDO: 13
  • TPSA: 425.55
  • ALOGS: -4.21
  • ROTB: 18

Drug dosage:

DoseUnitRoute
5 U P

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC H01BA05 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
POSTERIOR PITUITARY LOBE HORMONES
Vasopressin and analogues
MeSH PA D002317 Cardiovascular Agents
MeSH PA D003029 Coagulants
MeSH PA D006401 Hematologic Agents
MeSH PA D006490 Hemostatics
MeSH PA D014662 Vasoconstrictor Agents

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.47 acidic
pKa2 12.33 acidic
pKa3 12.66 acidic
pKa4 12.81 acidic
pKa5 13.19 acidic
pKa6 13.28 acidic
pKa7 13.55 acidic
pKa8 13.68 acidic
pKa9 10.12 Basic
pKa10 6.4 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07227 KEGG_DRUG
N0000170338 NUI
CHEBI:136020 CHEBI
CHEMBL1819440 ChEMBL_ID
2544 INN_ID
DB13464 DRUGBANK_ID
1KTH6N080W UNII
14257660 PUBCHEM_CID
7703 RXNORM
006913 NDDF
703839000 SNOMEDCT_US
D009951 MESH_DESCRIPTOR_UI
C0029276 UMLSCUI

Pharmaceutical products:

None