creatine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4661 | 57-00-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Pneumonia aspiration | 184.77 | 62.88 | 46 | 311 | 59225 | 64439150 |
| Gastrooesophageal reflux disease | 164.59 | 62.88 | 45 | 312 | 83098 | 64415277 |
| Coma | 162.25 | 62.88 | 45 | 312 | 87570 | 64410805 |
| Somnolence | 128.69 | 62.88 | 46 | 311 | 203599 | 64294776 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:50733 | Dietary Supplement |
| CHEBI has role | CHEBI:63726 | neuroprotective agents |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
| CHEBI has role | CHEBI:176497 | geroprotectors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 2.48 | acidic |
| pKa2 | 11.13 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4024927 | VUID |
| N0000170276 | NUI |
| 4024927 | VANDF |
| CHEBI:16919 | CHEBI |
| CRN | PDB_CHEM_ID |
| CHEMBL283800 | ChEMBL_ID |
| 4496 | IUPHAR_LIGAND_ID |
| DB00148 | DRUGBANK_ID |
| MU72812GK0 | UNII |
| 586 | PUBCHEM_CID |
| 2907 | RXNORM |
| NOCODE | MMSL |
| d04417 | MMSL |
| 008272 | NDDF |
| D003401 | MESH_DESCRIPTOR_UI |
| C0010286 | UMLSCUI |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Ginsamin Energy | HUMAN OTC DRUG LABEL | 5 | 44738-7001 | LIQUID | 10000 mg | ORAL | unapproved drug other | 3 sections |