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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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Smart API
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
tedisamil 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
4655
90961-53-8
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
KC-8857
tedisamil
tedisamil sesquifumarate
Molecular weight: 288.48
Formula: C19H32N2
CLOGP: 3.32
LIPINSKI: 0
HAC: 2
HDO: 0
TPSA: 6.48
ALOGS: -4.13
ROTB: 4
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
C01BD06
CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
ANTIARRHYTHMICS, CLASS I AND III
Antiarrhythmics, class III
CHEBI has role
CHEBI:38070
antiarrhythmic agent
MeSH PA
D000889
Anti-Arrhythmia Agents
MeSH PA
D002316
Cardiotonic Agents
MeSH PA
D002317
Cardiovascular Agents
MeSH PA
D020011
Protective Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.69
Basic
pKa2
7.78
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Potassium voltage-gated channel subfamily A member 7
Ion channel
KCNA7_MOUSE
BLOCKER
IC50
4.70
IUPHAR
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External reference:
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entries
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ID
Source
150501-62-5
SECONDARY_CAS_RN
2567
IUPHAR_LIGAND_ID
6297
INN_ID
65825
PUBCHEM_CID
713431000
SNOMEDCT_US
A5VAY2U3R8
UNII
C0076034
UMLSCUI
C059921
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:134747
CHEBI
CHEMBL113461
ChEMBL_ID
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Pharmaceutical products:
None
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tedisamil