Stem definition | Drug id | CAS RN |
---|---|---|
antiarrhythmics | 176 | 1951-25-3 |
Dose | Unit | Route |
---|---|---|
0.20 | g | O |
0.20 | g | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.70 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 41.37 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Vd (Volume of distribution) | 60 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 1.90 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.00 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 820 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 24, 1985 | FDA | WYETH PHARMS INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug interaction | 1122.38 | 12.78 | 1171 | 51692 | 208584 | 56030620 |
Atrial fibrillation | 992.11 | 12.78 | 819 | 52044 | 108078 | 56131126 |
Torsade de pointes | 815.43 | 12.78 | 339 | 52524 | 12101 | 56227103 |
Bradycardia | 796.68 | 12.78 | 592 | 52271 | 66912 | 56172292 |
Electrocardiogram QT prolonged | 708.05 | 12.78 | 507 | 52356 | 54081 | 56185123 |
Hyperthyroidism | 643.63 | 12.78 | 293 | 52570 | 13059 | 56226145 |
Acute kidney injury | 411.18 | 12.78 | 777 | 52086 | 239986 | 55999218 |
Ventricular tachycardia | 409.28 | 12.78 | 233 | 52630 | 16668 | 56222536 |
International normalised ratio increased | 366.61 | 12.78 | 315 | 52548 | 43726 | 56195478 |
Pulmonary toxicity | 342.43 | 12.78 | 161 | 52702 | 7722 | 56231482 |
Cardiac failure | 339.98 | 12.78 | 402 | 52461 | 81691 | 56157513 |
Myxoedema coma | 337.47 | 12.78 | 78 | 52785 | 328 | 56238876 |
Interstitial lung disease | 331.50 | 12.78 | 334 | 52529 | 56729 | 56182475 |
Rheumatoid arthritis | 263.46 | 12.78 | 27 | 52836 | 382577 | 55856627 |
Sinus bradycardia | 262.68 | 12.78 | 162 | 52701 | 13424 | 56225780 |
Hypothyroidism | 235.48 | 12.78 | 231 | 52632 | 37965 | 56201239 |
Ventricular fibrillation | 223.00 | 12.78 | 135 | 52728 | 10817 | 56228387 |
Hyperkalaemia | 221.96 | 12.78 | 256 | 52607 | 50609 | 56188595 |
Cardiogenic shock | 219.12 | 12.78 | 155 | 52708 | 16170 | 56223034 |
Pain | 210.21 | 12.78 | 189 | 52674 | 662995 | 55576209 |
Syncope | 206.59 | 12.78 | 367 | 52496 | 107832 | 56131372 |
Haematoma | 194.29 | 12.78 | 192 | 52671 | 31827 | 56207377 |
Gastrointestinal haemorrhage | 192.78 | 12.78 | 293 | 52570 | 75658 | 56163546 |
Hyponatraemia | 190.56 | 12.78 | 343 | 52520 | 101796 | 56137408 |
Hypotension | 188.94 | 12.78 | 590 | 52273 | 249918 | 55989286 |
Tachyarrhythmia | 182.66 | 12.78 | 86 | 52777 | 4135 | 56235069 |
Cardiac arrest | 182.04 | 12.78 | 306 | 52557 | 86008 | 56153196 |
Joint swelling | 163.85 | 12.78 | 36 | 52827 | 289764 | 55949440 |
Arthralgia | 159.85 | 12.78 | 142 | 52721 | 501527 | 55737677 |
Thyroiditis | 158.65 | 12.78 | 63 | 52800 | 1989 | 56237215 |
Renal failure | 150.27 | 12.78 | 325 | 52538 | 110175 | 56129029 |
Shock haemorrhagic | 143.06 | 12.78 | 95 | 52768 | 8938 | 56230266 |
Headache | 138.90 | 12.78 | 194 | 52669 | 558850 | 55680354 |
Cardiac failure congestive | 138.03 | 12.78 | 274 | 52589 | 87446 | 56151758 |
Synovitis | 133.15 | 12.78 | 4 | 52859 | 161301 | 56077903 |
Sinus node dysfunction | 131.75 | 12.78 | 70 | 52793 | 4364 | 56234840 |
Rash | 130.70 | 12.78 | 163 | 52700 | 492884 | 55746320 |
Glossodynia | 128.76 | 12.78 | 3 | 52860 | 152455 | 56086749 |
Arthropathy | 128.11 | 12.78 | 18 | 52845 | 200257 | 56038947 |
Atrial flutter | 127.55 | 12.78 | 89 | 52774 | 9080 | 56230124 |
Therapeutic product effect decreased | 127.42 | 12.78 | 8 | 52855 | 169444 | 56069760 |
Drug intolerance | 127.15 | 12.78 | 45 | 52818 | 264773 | 55974431 |
Alopecia | 124.55 | 12.78 | 60 | 52803 | 293398 | 55945806 |
Arrhythmia | 122.80 | 12.78 | 158 | 52705 | 34925 | 56204279 |
Drug ineffective | 121.62 | 12.78 | 450 | 52413 | 918539 | 55320665 |
Systemic lupus erythematosus | 120.46 | 12.78 | 14 | 52849 | 180064 | 56059140 |
Infusion related reaction | 119.98 | 12.78 | 25 | 52838 | 208906 | 56030298 |
Sinusitis | 119.05 | 12.78 | 21 | 52842 | 197560 | 56041644 |
Hypokalaemia | 110.78 | 12.78 | 262 | 52601 | 94175 | 56145029 |
Lactic acidosis | 103.58 | 12.78 | 146 | 52717 | 35200 | 56204004 |
Swelling | 103.27 | 12.78 | 48 | 52815 | 239723 | 55999481 |
Multiple organ dysfunction syndrome | 98.04 | 12.78 | 177 | 52686 | 52593 | 56186611 |
Long QT syndrome | 95.47 | 12.78 | 50 | 52813 | 3026 | 56236178 |
Anaemia | 95.26 | 12.78 | 499 | 52364 | 267012 | 55972192 |
Hypersensitivity | 94.97 | 12.78 | 62 | 52801 | 256346 | 55982858 |
Cerebral haemorrhage | 92.61 | 12.78 | 124 | 52739 | 28482 | 56210722 |
Labelled drug-drug interaction medication error | 92.53 | 12.78 | 81 | 52782 | 11505 | 56227699 |
Ventricular arrhythmia | 90.03 | 12.78 | 50 | 52813 | 3404 | 56235800 |
Wound | 89.86 | 12.78 | 12 | 52851 | 138792 | 56100412 |
Mitral valve incompetence | 88.76 | 12.78 | 97 | 52766 | 18056 | 56221148 |
Melaena | 87.59 | 12.78 | 120 | 52743 | 28170 | 56211034 |
Nasopharyngitis | 86.58 | 12.78 | 50 | 52813 | 220909 | 56018295 |
Fatigue | 84.47 | 12.78 | 418 | 52445 | 788134 | 55451070 |
Cardio-respiratory arrest | 83.62 | 12.78 | 170 | 52693 | 55151 | 56184053 |
Musculoskeletal stiffness | 82.94 | 12.78 | 22 | 52841 | 155985 | 56083219 |
Ventricular extrasystoles | 80.86 | 12.78 | 73 | 52790 | 10797 | 56228407 |
Hypoxia | 80.72 | 12.78 | 165 | 52698 | 53732 | 56185472 |
Fall | 79.57 | 12.78 | 591 | 52272 | 356919 | 55882285 |
Abdominal discomfort | 79.40 | 12.78 | 86 | 52777 | 277188 | 55962016 |
Alveolitis | 76.05 | 12.78 | 41 | 52822 | 2632 | 56236572 |
Cholestasis | 75.65 | 12.78 | 109 | 52754 | 26804 | 56212400 |
Rhabdomyolysis | 75.03 | 12.78 | 136 | 52727 | 40522 | 56198682 |
Pericarditis | 73.99 | 12.78 | 8 | 52855 | 108915 | 56130289 |
Respiratory failure | 73.37 | 12.78 | 226 | 52637 | 94836 | 56144368 |
Atrial tachycardia | 71.19 | 12.78 | 37 | 52826 | 2204 | 56237000 |
Infection | 68.07 | 12.78 | 53 | 52810 | 200153 | 56039051 |
Maternal exposure during pregnancy | 67.26 | 12.78 | 48 | 52815 | 189505 | 56049699 |
Atrioventricular block | 67.09 | 12.78 | 54 | 52809 | 6833 | 56232371 |
Cerebral haematoma | 65.17 | 12.78 | 40 | 52823 | 3283 | 56235921 |
Renal injury | 64.76 | 12.78 | 59 | 52804 | 8828 | 56230376 |
Injection site pain | 63.22 | 12.78 | 16 | 52847 | 117102 | 56122102 |
Rectal haemorrhage | 62.15 | 12.78 | 127 | 52736 | 41340 | 56197864 |
Pain in extremity | 61.63 | 12.78 | 116 | 52747 | 297315 | 55941889 |
Product use issue | 61.06 | 12.78 | 51 | 52812 | 185990 | 56053214 |
Toxicity to various agents | 60.98 | 12.78 | 390 | 52473 | 224174 | 56015030 |
Haematoma muscle | 58.55 | 12.78 | 25 | 52838 | 952 | 56238252 |
Brugada syndrome | 58.00 | 12.78 | 19 | 52844 | 339 | 56238865 |
Arterial haemorrhage | 57.93 | 12.78 | 29 | 52834 | 1596 | 56237608 |
Cardioversion | 57.56 | 12.78 | 26 | 52837 | 1135 | 56238069 |
Atrioventricular block complete | 57.07 | 12.78 | 51 | 52812 | 7443 | 56231761 |
Blood thyroid stimulating hormone increased | 56.71 | 12.78 | 48 | 52815 | 6515 | 56232689 |
Haemorrhage | 56.11 | 12.78 | 147 | 52716 | 56250 | 56182954 |
Hepatocellular injury | 55.82 | 12.78 | 94 | 52769 | 26420 | 56212784 |
Discomfort | 55.61 | 12.78 | 32 | 52831 | 141729 | 56097475 |
Orthopnoea | 55.38 | 12.78 | 45 | 52818 | 5771 | 56233433 |
Infusion site phlebitis | 55.26 | 12.78 | 13 | 52850 | 60 | 56239144 |
Therapeutic product effect incomplete | 54.39 | 12.78 | 16 | 52847 | 106015 | 56133189 |
Psoriatic arthropathy | 54.12 | 12.78 | 4 | 52859 | 74004 | 56165200 |
Lymphatic fistula | 53.43 | 12.78 | 22 | 52841 | 764 | 56238440 |
Contraindicated product administered | 53.04 | 12.78 | 58 | 52805 | 186228 | 56052976 |
Coronary artery disease | 53.03 | 12.78 | 100 | 52763 | 30696 | 56208508 |
Femoral hernia incarcerated | 53.02 | 12.78 | 22 | 52841 | 779 | 56238425 |
Migraine | 52.73 | 12.78 | 9 | 52854 | 86788 | 56152416 |
Blood loss anaemia | 52.63 | 12.78 | 51 | 52812 | 8246 | 56230958 |
Hypoaesthesia | 52.62 | 12.78 | 34 | 52829 | 141457 | 56097747 |
Pulmonary hypertension | 52.58 | 12.78 | 109 | 52754 | 35835 | 56203369 |
Lung disorder | 52.23 | 12.78 | 137 | 52726 | 52460 | 56186744 |
Urticaria | 52.15 | 12.78 | 36 | 52827 | 144640 | 56094564 |
Neuromyopathy | 51.86 | 12.78 | 20 | 52843 | 583 | 56238621 |
Pulmonary fibrosis | 51.70 | 12.78 | 97 | 52766 | 29661 | 56209543 |
Ischaemic stroke | 51.46 | 12.78 | 71 | 52792 | 16771 | 56222433 |
Cardioactive drug level increased | 51.34 | 12.78 | 29 | 52834 | 2040 | 56237164 |
Stomatitis | 50.71 | 12.78 | 25 | 52838 | 120785 | 56118419 |
Acute respiratory distress syndrome | 50.57 | 12.78 | 81 | 52782 | 21845 | 56217359 |
Weight increased | 49.87 | 12.78 | 87 | 52776 | 229616 | 56009588 |
Drug level increased | 49.78 | 12.78 | 78 | 52785 | 20647 | 56218557 |
Treatment failure | 49.68 | 12.78 | 52 | 52811 | 170340 | 56068864 |
Faecaloma | 49.59 | 12.78 | 47 | 52816 | 7394 | 56231810 |
Arthritis | 49.54 | 12.78 | 16 | 52847 | 99836 | 56139368 |
Toxic skin eruption | 49.35 | 12.78 | 58 | 52805 | 11681 | 56227523 |
Pancreatic steatosis | 49.01 | 12.78 | 22 | 52841 | 946 | 56238258 |
Hyperglobulinaemia | 47.77 | 12.78 | 8 | 52855 | 0 | 56239204 |
Exposure during pregnancy | 47.73 | 12.78 | 35 | 52828 | 136307 | 56102897 |
Blood cholesterol increased | 47.61 | 12.78 | 6 | 52857 | 72573 | 56166631 |
Respiratory distress | 47.46 | 12.78 | 97 | 52766 | 31570 | 56207634 |
Haematuria | 46.93 | 12.78 | 88 | 52775 | 26899 | 56212305 |
Product dose omission issue | 46.80 | 12.78 | 75 | 52788 | 204678 | 56034526 |
Pyrexia | 46.35 | 12.78 | 219 | 52644 | 418554 | 55820650 |
Muscle spasms | 45.87 | 12.78 | 37 | 52826 | 137334 | 56101870 |
Haemarthrosis | 45.76 | 12.78 | 31 | 52832 | 3013 | 56236191 |
Urinary retention | 45.68 | 12.78 | 89 | 52774 | 27985 | 56211219 |
Wound infection pseudomonas | 45.50 | 12.78 | 23 | 52840 | 1292 | 56237912 |
Dyspnoea | 45.25 | 12.78 | 794 | 52069 | 591783 | 55647421 |
Injection site erythema | 44.96 | 12.78 | 9 | 52854 | 77439 | 56161765 |
Myocardial infarction | 44.48 | 12.78 | 189 | 52674 | 92681 | 56146523 |
Diarrhoea | 44.48 | 12.78 | 385 | 52478 | 638122 | 55601082 |
Coagulopathy | 44.34 | 12.78 | 70 | 52793 | 18646 | 56220558 |
Pruritus | 44.22 | 12.78 | 151 | 52712 | 316472 | 55922732 |
Fibromyalgia | 44.22 | 12.78 | 3 | 52860 | 59600 | 56179604 |
Psoriasis | 43.99 | 12.78 | 16 | 52847 | 92676 | 56146528 |
Nodal rhythm | 43.58 | 12.78 | 24 | 52839 | 1607 | 56237597 |
Septic shock | 42.68 | 12.78 | 140 | 52723 | 60695 | 56178509 |
Keratopathy | 42.53 | 12.78 | 17 | 52846 | 546 | 56238658 |
Thyrotoxic crisis | 42.44 | 12.78 | 19 | 52844 | 812 | 56238392 |
Bundle branch block left | 42.04 | 12.78 | 40 | 52823 | 6322 | 56232882 |
Left ventricular dysfunction | 41.93 | 12.78 | 52 | 52811 | 11071 | 56228133 |
Corneal deposits | 41.38 | 12.78 | 14 | 52849 | 277 | 56238927 |
Back pain | 41.20 | 12.78 | 102 | 52761 | 237068 | 56002136 |
Cerebellar syndrome | 39.89 | 12.78 | 30 | 52833 | 3437 | 56235767 |
Ill-defined disorder | 39.72 | 12.78 | 8 | 52855 | 68535 | 56170669 |
Acute respiratory failure | 39.62 | 12.78 | 89 | 52774 | 30905 | 56208299 |
Hepatic cyst | 39.26 | 12.78 | 34 | 52829 | 4759 | 56234445 |
Hypomagnesaemia | 39.13 | 12.78 | 78 | 52785 | 24937 | 56214267 |
Bradyarrhythmia | 39.07 | 12.78 | 24 | 52839 | 1972 | 56237232 |
Ecchymosis | 38.37 | 12.78 | 48 | 52815 | 10308 | 56228896 |
Asthma | 38.12 | 12.78 | 30 | 52833 | 112740 | 56126464 |
Anuria | 38.09 | 12.78 | 51 | 52812 | 11709 | 56227495 |
Cerebellar haematoma | 37.91 | 12.78 | 14 | 52849 | 361 | 56238843 |
Tricuspid valve incompetence | 37.71 | 12.78 | 54 | 52809 | 13199 | 56226005 |
Listless | 37.66 | 12.78 | 26 | 52837 | 2606 | 56236598 |
Extravasation | 37.47 | 12.78 | 24 | 52839 | 2123 | 56237081 |
Seroma | 37.47 | 12.78 | 23 | 52840 | 1888 | 56237316 |
Respiratory acidosis | 37.44 | 12.78 | 37 | 52826 | 6126 | 56233078 |
Extrasystoles | 37.22 | 12.78 | 33 | 52830 | 4766 | 56234438 |
Subdural haematoma | 36.95 | 12.78 | 54 | 52809 | 13445 | 56225759 |
Depression | 36.60 | 12.78 | 71 | 52792 | 180046 | 56059158 |
Pleural effusion | 36.42 | 12.78 | 168 | 52695 | 85312 | 56153892 |
Cardiac ablation | 36.21 | 12.78 | 20 | 52843 | 1347 | 56237857 |
Injection site reaction | 35.92 | 12.78 | 4 | 52859 | 53243 | 56185961 |
Irritable bowel syndrome | 35.71 | 12.78 | 10 | 52853 | 68448 | 56170756 |
Device stimulation issue | 35.60 | 12.78 | 9 | 52854 | 59 | 56239145 |
Alveolar proteinosis | 35.58 | 12.78 | 13 | 52850 | 325 | 56238879 |
Nausea | 35.25 | 12.78 | 506 | 52357 | 763672 | 55475532 |
Hypoglycaemia | 35.24 | 12.78 | 124 | 52739 | 55691 | 56183513 |
Sudden death | 34.69 | 12.78 | 44 | 52819 | 9581 | 56229623 |
Myalgia | 34.46 | 12.78 | 44 | 52819 | 131981 | 56107223 |
Inflammatory marker increased | 34.13 | 12.78 | 35 | 52828 | 6055 | 56233149 |
Off label use | 34.11 | 12.78 | 346 | 52517 | 555834 | 55683370 |
Prothrombin time shortened | 33.90 | 12.78 | 21 | 52842 | 1752 | 56237452 |
Reduced facial expression | 33.65 | 12.78 | 21 | 52842 | 1775 | 56237429 |
Aortic valve stenosis | 33.50 | 12.78 | 26 | 52837 | 3121 | 56236083 |
Agranulocytosis | 33.47 | 12.78 | 69 | 52794 | 22590 | 56216614 |
Peripheral swelling | 33.39 | 12.78 | 111 | 52752 | 234615 | 56004589 |
Craniocerebral injury | 33.26 | 12.78 | 24 | 52839 | 2580 | 56236624 |
Spontaneous haematoma | 33.20 | 12.78 | 16 | 52847 | 810 | 56238394 |
Head injury | 33.18 | 12.78 | 73 | 52790 | 24993 | 56214211 |
Muscle haemorrhage | 32.59 | 12.78 | 25 | 52838 | 2950 | 56236254 |
Cardiac disorder | 32.54 | 12.78 | 106 | 52757 | 45781 | 56193423 |
Organising pneumonia | 32.35 | 12.78 | 32 | 52831 | 5303 | 56233901 |
Mixed liver injury | 32.35 | 12.78 | 28 | 52835 | 3916 | 56235288 |
Pneumonitis | 32.13 | 12.78 | 83 | 52780 | 31481 | 56207723 |
Medication error | 32.03 | 12.78 | 100 | 52763 | 42235 | 56196969 |
Hepatic failure | 32.00 | 12.78 | 86 | 52777 | 33400 | 56205804 |
Right ventricular failure | 31.76 | 12.78 | 56 | 52807 | 16323 | 56222881 |
Suicide attempt | 31.01 | 12.78 | 8 | 52855 | 57828 | 56181376 |
Gastrooesophageal reflux disease | 30.95 | 12.78 | 20 | 52843 | 83237 | 56155967 |
Cornea verticillata | 30.92 | 12.78 | 9 | 52854 | 106 | 56239098 |
Arrhythmia supraventricular | 30.78 | 12.78 | 16 | 52847 | 953 | 56238251 |
Anticoagulation drug level increased | 30.49 | 12.78 | 10 | 52853 | 179 | 56239025 |
Subarachnoid haemorrhage | 30.49 | 12.78 | 45 | 52818 | 11302 | 56227902 |
Hepatic enzyme increased | 30.30 | 12.78 | 73 | 52790 | 171311 | 56067893 |
Abortion spontaneous | 30.25 | 12.78 | 3 | 52860 | 43750 | 56195454 |
Chills | 30.24 | 12.78 | 31 | 52832 | 102573 | 56136631 |
Haemorrhagic stroke | 30.19 | 12.78 | 31 | 52832 | 5372 | 56233832 |
Iodine overload | 29.86 | 12.78 | 5 | 52858 | 0 | 56239204 |
Renal impairment | 29.62 | 12.78 | 152 | 52711 | 80561 | 56158643 |
Haemorrhagic diathesis | 29.51 | 12.78 | 27 | 52836 | 4061 | 56235143 |
Oliguria | 29.50 | 12.78 | 38 | 52825 | 8402 | 56230802 |
Overdose | 29.41 | 12.78 | 185 | 52678 | 105645 | 56133559 |
Lower gastrointestinal haemorrhage | 29.36 | 12.78 | 35 | 52828 | 7152 | 56232052 |
Ventricular tachyarrhythmia | 29.30 | 12.78 | 9 | 52854 | 129 | 56239075 |
Insomnia | 29.19 | 12.78 | 88 | 52775 | 191772 | 56047432 |
Rales | 29.15 | 12.78 | 43 | 52820 | 10797 | 56228407 |
Pericardial haemorrhage | 29.05 | 12.78 | 18 | 52845 | 1502 | 56237702 |
Glomerular filtration rate decreased | 29.05 | 12.78 | 46 | 52817 | 12283 | 56226921 |
Acute hepatic failure | 28.75 | 12.78 | 54 | 52809 | 16524 | 56222680 |
Mediastinal haematoma | 28.31 | 12.78 | 8 | 52855 | 84 | 56239120 |
Knee arthroplasty | 28.21 | 12.78 | 4 | 52859 | 44255 | 56194949 |
General physical health deterioration | 28.03 | 12.78 | 263 | 52600 | 169747 | 56069457 |
White blood cell count decreased | 27.97 | 12.78 | 47 | 52816 | 125943 | 56113261 |
Hypervolaemia | 27.37 | 12.78 | 70 | 52793 | 26388 | 56212816 |
Intentional product use issue | 27.33 | 12.78 | 32 | 52831 | 99701 | 56139503 |
Oedema peripheral | 27.28 | 12.78 | 263 | 52600 | 170991 | 56068213 |
Myxoedema | 27.27 | 12.78 | 8 | 52855 | 97 | 56239107 |
Herpes zoster | 27.17 | 12.78 | 19 | 52844 | 75870 | 56163334 |
Goitre congenital | 26.92 | 12.78 | 5 | 52858 | 4 | 56239200 |
Heparin-induced thrombocytopenia | 26.91 | 12.78 | 26 | 52837 | 4188 | 56235016 |
Hepatitis acute | 26.69 | 12.78 | 36 | 52827 | 8321 | 56230883 |
Subcutaneous haematoma | 26.00 | 12.78 | 17 | 52846 | 1557 | 56237647 |
Cardiac failure chronic | 25.79 | 12.78 | 25 | 52838 | 4042 | 56235162 |
Diverticulum intestinal | 25.72 | 12.78 | 31 | 52832 | 6409 | 56232795 |
Nodal arrhythmia | 25.59 | 12.78 | 15 | 52848 | 1132 | 56238072 |
Shock | 25.14 | 12.78 | 60 | 52803 | 21668 | 56217536 |
Myopathy | 25.06 | 12.78 | 38 | 52825 | 9774 | 56229430 |
Gastrointestinal disorder | 25.06 | 12.78 | 42 | 52821 | 112660 | 56126544 |
Oesophageal squamous cell carcinoma | 25.00 | 12.78 | 8 | 52855 | 132 | 56239072 |
Acute generalised exanthematous pustulosis | 24.90 | 12.78 | 38 | 52825 | 9831 | 56229373 |
Drug hypersensitivity | 24.82 | 12.78 | 154 | 52709 | 275051 | 55964153 |
Asthenia | 24.80 | 12.78 | 456 | 52407 | 342517 | 55896687 |
Encephalopathy | 24.50 | 12.78 | 81 | 52782 | 35244 | 56203960 |
Atrioventricular block first degree | 24.50 | 12.78 | 31 | 52832 | 6734 | 56232470 |
Device capturing issue | 24.48 | 12.78 | 6 | 52857 | 34 | 56239170 |
Coronary artery bypass | 24.45 | 12.78 | 19 | 52844 | 2284 | 56236920 |
Central nervous system injury | 24.41 | 12.78 | 8 | 52855 | 143 | 56239061 |
Pericardial effusion | 24.18 | 12.78 | 68 | 52795 | 27107 | 56212097 |
Sinoatrial block | 24.13 | 12.78 | 13 | 52850 | 833 | 56238371 |
Eosinophilia | 23.83 | 12.78 | 56 | 52807 | 20021 | 56219183 |
Abdominal pain upper | 23.55 | 12.78 | 87 | 52776 | 178226 | 56060978 |
Foreign body | 23.51 | 12.78 | 18 | 52845 | 2118 | 56237086 |
Abdominal wall haematoma | 23.42 | 12.78 | 20 | 52843 | 2747 | 56236457 |
Injection site bruising | 23.38 | 12.78 | 4 | 52859 | 38517 | 56200687 |
Cardiac arrest neonatal | 23.21 | 12.78 | 7 | 52856 | 94 | 56239110 |
Thrombocytopenia | 23.08 | 12.78 | 212 | 52651 | 136012 | 56103192 |
Pulmonary alveolar haemorrhage | 22.99 | 12.78 | 24 | 52839 | 4240 | 56234964 |
Electrocardiogram QRS complex prolonged | 22.96 | 12.78 | 27 | 52836 | 5440 | 56233764 |
Blister | 22.92 | 12.78 | 42 | 52821 | 108845 | 56130359 |
Transaminases increased | 22.73 | 12.78 | 69 | 52794 | 28701 | 56210503 |
Hypoxic-ischaemic encephalopathy | 22.70 | 12.78 | 23 | 52840 | 3922 | 56235282 |
Intra-abdominal haematoma | 22.70 | 12.78 | 16 | 52847 | 1658 | 56237546 |
Liver function test abnormal | 22.67 | 12.78 | 94 | 52769 | 45577 | 56193627 |
Musculoskeletal pain | 22.27 | 12.78 | 26 | 52837 | 81126 | 56158078 |
Splenic haemorrhage | 22.16 | 12.78 | 8 | 52855 | 193 | 56239011 |
Cardiac failure acute | 22.15 | 12.78 | 34 | 52829 | 8839 | 56230365 |
Thyroxine increased | 22.13 | 12.78 | 11 | 52852 | 596 | 56238608 |
Potentiating drug interaction | 22.12 | 12.78 | 23 | 52840 | 4043 | 56235161 |
Retroperitoneal haemorrhage | 22.11 | 12.78 | 19 | 52844 | 2631 | 56236573 |
Hepatic cytolysis | 22.07 | 12.78 | 38 | 52825 | 10868 | 56228336 |
Constipation | 22.05 | 12.78 | 106 | 52757 | 201837 | 56037367 |
Feeling abnormal | 21.99 | 12.78 | 59 | 52804 | 133543 | 56105661 |
Splenic injury | 21.90 | 12.78 | 8 | 52855 | 200 | 56239004 |
Presyncope | 21.78 | 12.78 | 63 | 52800 | 25519 | 56213685 |
Acute pulmonary oedema | 21.68 | 12.78 | 31 | 52832 | 7566 | 56231638 |
Bone pain | 21.64 | 12.78 | 10 | 52853 | 50175 | 56189029 |
Retroperitoneal haematoma | 21.61 | 12.78 | 19 | 52844 | 2714 | 56236490 |
Hypochromasia | 21.34 | 12.78 | 9 | 52854 | 332 | 56238872 |
Prerenal failure | 21.23 | 12.78 | 15 | 52848 | 1560 | 56237644 |
Paraesthesia | 21.21 | 12.78 | 58 | 52805 | 130456 | 56108748 |
Lower respiratory tract infection | 21.00 | 12.78 | 48 | 52815 | 114746 | 56124458 |
Influenza like illness | 20.89 | 12.78 | 16 | 52847 | 60972 | 56178232 |
Cyanosis | 20.88 | 12.78 | 46 | 52817 | 15764 | 56223440 |
Type 2 diabetes mellitus | 20.74 | 12.78 | 9 | 52854 | 46853 | 56192351 |
Aortic arteriosclerosis | 20.71 | 12.78 | 26 | 52837 | 5604 | 56233600 |
Pulmonary oedema | 20.66 | 12.78 | 99 | 52764 | 51044 | 56188160 |
Cardioactive drug level above therapeutic | 20.53 | 12.78 | 7 | 52856 | 142 | 56239062 |
Cardiac tamponade | 20.51 | 12.78 | 23 | 52840 | 4403 | 56234801 |
Upper respiratory tract infection | 20.48 | 12.78 | 22 | 52841 | 71266 | 56167938 |
Device pacing issue | 20.43 | 12.78 | 6 | 52857 | 73 | 56239131 |
Drug-induced liver injury | 20.42 | 12.78 | 75 | 52788 | 34387 | 56204817 |
Haemorrhage intracranial | 20.22 | 12.78 | 40 | 52823 | 12715 | 56226489 |
Local anaesthetic systemic toxicity | 20.16 | 12.78 | 11 | 52852 | 723 | 56238481 |
Neck pain | 20.02 | 12.78 | 17 | 52846 | 61538 | 56177666 |
Palpitations | 19.97 | 12.78 | 161 | 52702 | 99511 | 56139693 |
C-reactive protein abnormal | 19.91 | 12.78 | 5 | 52858 | 36804 | 56202400 |
Injection site swelling | 19.88 | 12.78 | 8 | 52855 | 43570 | 56195634 |
Red blood cell sedimentation rate increased | 19.76 | 12.78 | 5 | 52858 | 36618 | 56202586 |
Blood creatinine increased | 19.73 | 12.78 | 136 | 52727 | 80055 | 56159149 |
Wound dehiscence | 19.73 | 12.78 | 23 | 52840 | 4592 | 56234612 |
Osteoarthritis | 19.69 | 12.78 | 28 | 52835 | 80268 | 56158936 |
Anti-thyroid antibody positive | 19.56 | 12.78 | 9 | 52854 | 410 | 56238794 |
Memory impairment | 19.48 | 12.78 | 32 | 52831 | 86525 | 56152679 |
Dyschromatopsia | 19.42 | 12.78 | 9 | 52854 | 417 | 56238787 |
Propionibacterium infection | 19.37 | 12.78 | 5 | 52858 | 36 | 56239168 |
Hepatitis fulminant | 19.03 | 12.78 | 19 | 52844 | 3185 | 56236019 |
Pelvic fracture | 19.00 | 12.78 | 38 | 52825 | 12175 | 56227029 |
Escherichia infection | 18.92 | 12.78 | 37 | 52826 | 11662 | 56227542 |
Subdural haemorrhage | 18.91 | 12.78 | 18 | 52845 | 2846 | 56236358 |
Prothrombin time prolonged | 18.90 | 12.78 | 32 | 52831 | 9028 | 56230176 |
Activated partial thromboplastin time prolonged | 18.90 | 12.78 | 27 | 52836 | 6585 | 56232619 |
Oropharyngeal pain | 18.83 | 12.78 | 31 | 52832 | 83757 | 56155447 |
Thyroiditis acute | 18.75 | 12.78 | 6 | 52857 | 99 | 56239105 |
Optic disc haemorrhage | 18.69 | 12.78 | 6 | 52857 | 100 | 56239104 |
Thyroxine free increased | 18.60 | 12.78 | 11 | 52852 | 844 | 56238360 |
Anisocytosis | 18.56 | 12.78 | 10 | 52853 | 641 | 56238563 |
Throat irritation | 18.55 | 12.78 | 4 | 52859 | 32679 | 56206525 |
Hypoglycaemic seizure | 18.52 | 12.78 | 9 | 52854 | 464 | 56238740 |
Intentional overdose | 18.50 | 12.78 | 22 | 52841 | 68095 | 56171109 |
Altered visual depth perception | 18.48 | 12.78 | 8 | 52855 | 315 | 56238889 |
Adverse event | 18.37 | 12.78 | 15 | 52848 | 55361 | 56183843 |
Conduction disorder | 18.29 | 12.78 | 13 | 52850 | 1365 | 56237839 |
Prescription drug used without a prescription | 18.18 | 12.78 | 15 | 52848 | 1965 | 56237239 |
Fear | 18.15 | 12.78 | 42 | 52821 | 14866 | 56224338 |
Ischaemic hepatitis | 18.15 | 12.78 | 15 | 52848 | 1970 | 56237234 |
Night sweats | 18.10 | 12.78 | 8 | 52855 | 41205 | 56197999 |
Thyroglobulin increased | 18.10 | 12.78 | 5 | 52858 | 48 | 56239156 |
Anhedonia | 18.07 | 12.78 | 33 | 52830 | 9881 | 56229323 |
Myocardial ischaemia | 18.02 | 12.78 | 37 | 52826 | 12079 | 56227125 |
Chorea | 18.00 | 12.78 | 13 | 52850 | 1399 | 56237805 |
Electrocardiogram PR prolongation | 17.97 | 12.78 | 10 | 52853 | 683 | 56238521 |
Pharyngeal haematoma | 17.92 | 12.78 | 5 | 52858 | 50 | 56239154 |
Febrile neutropenia | 17.83 | 12.78 | 46 | 52817 | 105499 | 56133705 |
Congenital hypothyroidism | 17.54 | 12.78 | 7 | 52856 | 224 | 56238980 |
Neovascular age-related macular degeneration | 17.51 | 12.78 | 7 | 52856 | 225 | 56238979 |
Circulatory collapse | 17.48 | 12.78 | 51 | 52812 | 20752 | 56218452 |
Haemorrhagic thyroid cyst | 17.46 | 12.78 | 4 | 52859 | 16 | 56239188 |
Drug level above therapeutic | 17.42 | 12.78 | 21 | 52842 | 4341 | 56234863 |
Chronic kidney disease | 17.42 | 12.78 | 82 | 52781 | 41974 | 56197230 |
Ear infection | 17.42 | 12.78 | 4 | 52859 | 31291 | 56207913 |
Petechiae | 17.29 | 12.78 | 38 | 52825 | 13001 | 56226203 |
Ear pain | 17.09 | 12.78 | 4 | 52859 | 30886 | 56208318 |
Head discomfort | 17.06 | 12.78 | 36 | 52827 | 11978 | 56227226 |
Tri-iodothyronine increased | 16.93 | 12.78 | 6 | 52857 | 137 | 56239067 |
Ataxia | 16.90 | 12.78 | 40 | 52823 | 14363 | 56224841 |
Compensatory sweating | 16.74 | 12.78 | 4 | 52859 | 20 | 56239184 |
Electrocardiogram T wave inversion | 16.58 | 12.78 | 18 | 52845 | 3325 | 56235879 |
Apathy | 16.47 | 12.78 | 28 | 52835 | 7926 | 56231278 |
Swelling face | 16.45 | 12.78 | 17 | 52846 | 56052 | 56183152 |
Secondary hyperthyroidism | 16.42 | 12.78 | 4 | 52859 | 22 | 56239182 |
Death | 16.36 | 12.78 | 428 | 52435 | 340998 | 55898206 |
Dyspnoea at rest | 16.29 | 12.78 | 19 | 52844 | 3794 | 56235410 |
Disease progression | 16.16 | 12.78 | 48 | 52815 | 105125 | 56134079 |
Electrocardiogram QRS complex shortened | 16.15 | 12.78 | 8 | 52855 | 430 | 56238774 |
Eosinophilic pneumonia | 16.14 | 12.78 | 14 | 52849 | 1963 | 56237241 |
Impaired healing | 16.13 | 12.78 | 36 | 52827 | 86805 | 56152399 |
Drug clearance decreased | 16.13 | 12.78 | 12 | 52851 | 1352 | 56237852 |
Tubulointerstitial nephritis | 16.12 | 12.78 | 43 | 52820 | 16622 | 56222582 |
Anaphylactic reaction | 16.08 | 12.78 | 19 | 52844 | 58976 | 56180228 |
Cardiovascular insufficiency | 16.07 | 12.78 | 12 | 52851 | 1360 | 56237844 |
Ejection fraction decreased | 16.06 | 12.78 | 48 | 52815 | 19793 | 56219411 |
Kidney malrotation | 15.99 | 12.78 | 4 | 52859 | 25 | 56239179 |
Gastroenteritis aeromonas | 15.99 | 12.78 | 4 | 52859 | 25 | 56239179 |
Neutrophil count decreased | 15.91 | 12.78 | 14 | 52849 | 49808 | 56189396 |
Low cardiac output syndrome | 15.84 | 12.78 | 7 | 52856 | 290 | 56238914 |
Apnoea | 15.67 | 12.78 | 26 | 52837 | 7216 | 56231988 |
Therapeutic response decreased | 15.47 | 12.78 | 16 | 52847 | 52742 | 56186462 |
Endovenous ablation | 15.38 | 12.78 | 3 | 52860 | 4 | 56239200 |
Lip swelling | 15.36 | 12.78 | 3 | 52860 | 26269 | 56212935 |
Infective pericardial effusion | 15.35 | 12.78 | 4 | 52859 | 30 | 56239174 |
Suicidal ideation | 15.31 | 12.78 | 19 | 52844 | 57723 | 56181481 |
Electrocardiogram U wave present | 15.07 | 12.78 | 5 | 52858 | 93 | 56239111 |
Optic atrophy | 15.06 | 12.78 | 11 | 52852 | 1205 | 56237999 |
Splenic rupture | 14.97 | 12.78 | 11 | 52852 | 1216 | 56237988 |
Coagulation test abnormal | 14.95 | 12.78 | 9 | 52854 | 713 | 56238491 |
Atrioventricular block second degree | 14.94 | 12.78 | 18 | 52845 | 3718 | 56235486 |
Sedation | 14.94 | 12.78 | 7 | 52856 | 34847 | 56204357 |
Blood pressure increased | 14.81 | 12.78 | 78 | 52785 | 145098 | 56094106 |
Congestive hepatopathy | 14.79 | 12.78 | 15 | 52848 | 2561 | 56236643 |
Hyperchloraemia | 14.78 | 12.78 | 9 | 52854 | 728 | 56238476 |
Cutaneous lupus erythematosus | 14.75 | 12.78 | 15 | 52848 | 2569 | 56236635 |
Cardiovascular disorder | 14.74 | 12.78 | 32 | 52831 | 10857 | 56228347 |
Renal function test abnormal | 14.74 | 12.78 | 16 | 52847 | 2955 | 56236249 |
Oesophageal adenocarcinoma recurrent | 14.71 | 12.78 | 4 | 52859 | 36 | 56239168 |
Illness | 14.69 | 12.78 | 7 | 52856 | 34504 | 56204700 |
Supraventricular tachycardia | 14.62 | 12.78 | 36 | 52827 | 13255 | 56225949 |
Therapy non-responder | 14.45 | 12.78 | 22 | 52841 | 61333 | 56177871 |
Extradural haematoma | 14.44 | 12.78 | 12 | 52851 | 1588 | 56237616 |
Electrocardiogram T wave abnormal | 14.40 | 12.78 | 14 | 52849 | 2272 | 56236932 |
Paroxysmal arrhythmia | 14.33 | 12.78 | 4 | 52859 | 40 | 56239164 |
Dehydration | 14.32 | 12.78 | 219 | 52644 | 158606 | 56080598 |
Atrioventricular dissociation | 14.26 | 12.78 | 6 | 52857 | 220 | 56238984 |
Optic neuropathy | 14.26 | 12.78 | 13 | 52850 | 1947 | 56237257 |
Lung consolidation | 14.20 | 12.78 | 18 | 52845 | 3916 | 56235288 |
Hypocoagulable state | 14.20 | 12.78 | 10 | 52853 | 1035 | 56238169 |
Erythema | 14.17 | 12.78 | 87 | 52776 | 155852 | 56083352 |
Electrocardiogram T wave alternans | 14.16 | 12.78 | 4 | 52859 | 42 | 56239162 |
Photosensitivity reaction | 14.10 | 12.78 | 36 | 52827 | 13557 | 56225647 |
Oral mucosa haematoma | 14.02 | 12.78 | 3 | 52860 | 8 | 56239196 |
Hypovolaemic shock | 13.99 | 12.78 | 21 | 52842 | 5352 | 56233852 |
Lung infiltration | 13.85 | 12.78 | 36 | 52827 | 13702 | 56225502 |
Left ventricular failure | 13.69 | 12.78 | 20 | 52843 | 4976 | 56234228 |
Haemoglobin decreased | 13.69 | 12.78 | 189 | 52674 | 133948 | 56105256 |
Cerebrovascular accident | 13.66 | 12.78 | 148 | 52715 | 99122 | 56140082 |
Sopor | 13.65 | 12.78 | 47 | 52816 | 20875 | 56218329 |
Pulseless electrical activity | 13.60 | 12.78 | 24 | 52839 | 7000 | 56232204 |
Eosinophilic pleural effusion | 13.60 | 12.78 | 4 | 52859 | 49 | 56239155 |
Eructation | 13.51 | 12.78 | 25 | 52838 | 7563 | 56231641 |
Cardiomegaly | 13.48 | 12.78 | 40 | 52823 | 16427 | 56222777 |
Goitre | 13.41 | 12.78 | 21 | 52842 | 5552 | 56233652 |
Foot deformity | 13.35 | 12.78 | 3 | 52860 | 23822 | 56215382 |
Eosinophilia myalgia syndrome | 13.30 | 12.78 | 3 | 52860 | 11 | 56239193 |
Aortic valve incompetence | 13.30 | 12.78 | 21 | 52842 | 5591 | 56233613 |
Groin pain | 13.28 | 12.78 | 28 | 52835 | 9312 | 56229892 |
Monoclonal gammopathy | 13.24 | 12.78 | 8 | 52855 | 638 | 56238566 |
Bullous haemorrhagic dermatosis | 13.17 | 12.78 | 4 | 52859 | 55 | 56239149 |
Respiratory alkalosis | 13.11 | 12.78 | 14 | 52849 | 2537 | 56236667 |
Hepatitis toxic | 13.10 | 12.78 | 15 | 52848 | 2937 | 56236267 |
Thyroiditis chronic | 13.10 | 12.78 | 3 | 52860 | 12 | 56239192 |
Toxic epidermal necrolysis | 13.08 | 12.78 | 48 | 52815 | 21994 | 56217210 |
Haemodynamic instability | 13.06 | 12.78 | 26 | 52837 | 8303 | 56230901 |
Lymphocyte count decreased | 12.95 | 12.78 | 5 | 52858 | 27934 | 56211270 |
Pancreatitis | 12.85 | 12.78 | 14 | 52849 | 45066 | 56194138 |
Concomitant disease aggravated | 12.85 | 12.78 | 26 | 52837 | 8400 | 56230804 |
Loss of consciousness | 12.80 | 12.78 | 158 | 52705 | 109191 | 56130013 |
Arterial insufficiency | 12.80 | 12.78 | 5 | 52858 | 151 | 56239053 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hyperthyroidism | 1798.39 | 11.50 | 722 | 74358 | 8909 | 31613355 |
Pulmonary toxicity | 692.88 | 11.50 | 310 | 74770 | 5067 | 31617197 |
Ventricular tachycardia | 688.40 | 11.50 | 517 | 74563 | 23184 | 31599080 |
Atrial fibrillation | 617.57 | 11.50 | 1025 | 74055 | 112758 | 31509506 |
Drug interaction | 541.19 | 11.50 | 1384 | 73696 | 207159 | 31415105 |
Bradycardia | 476.72 | 11.50 | 697 | 74383 | 68630 | 31553634 |
Interstitial lung disease | 468.82 | 11.50 | 649 | 74431 | 60754 | 31561510 |
Cardiac failure | 466.75 | 11.50 | 775 | 74305 | 85178 | 31537086 |
Thyroiditis | 366.52 | 11.50 | 151 | 74929 | 1992 | 31620272 |
Hypothyroidism | 337.02 | 11.50 | 304 | 74776 | 17643 | 31604621 |
Electrocardiogram QT prolonged | 331.80 | 11.50 | 429 | 74651 | 37558 | 31584706 |
Torsade de pointes | 318.80 | 11.50 | 200 | 74880 | 6650 | 31615614 |
Pulmonary fibrosis | 271.87 | 11.50 | 261 | 74819 | 16399 | 31605865 |
Cardiogenic shock | 262.75 | 11.50 | 294 | 74786 | 22114 | 31600150 |
Ventricular fibrillation | 260.90 | 11.50 | 270 | 74810 | 18578 | 31603686 |
Thyrotoxic crisis | 196.79 | 11.50 | 61 | 75019 | 321 | 31621943 |
International normalised ratio increased | 180.29 | 11.50 | 357 | 74723 | 44866 | 31577398 |
Acute kidney injury | 174.28 | 11.50 | 1195 | 73885 | 278519 | 31343745 |
Cardiac failure congestive | 172.78 | 11.50 | 495 | 74585 | 78892 | 31543372 |
Pulmonary alveolar haemorrhage | 151.99 | 11.50 | 127 | 74953 | 6639 | 31615625 |
Hypotension | 149.80 | 11.50 | 911 | 74169 | 203707 | 31418557 |
Ejection fraction decreased | 146.04 | 11.50 | 193 | 74887 | 17241 | 31605023 |
Multiple organ dysfunction syndrome | 145.21 | 11.50 | 422 | 74658 | 67781 | 31554483 |
Ventricular arrhythmia | 142.52 | 11.50 | 107 | 74973 | 4784 | 31617480 |
Appendicolith | 140.11 | 11.50 | 113 | 74967 | 5618 | 31616646 |
Completed suicide | 125.71 | 11.50 | 31 | 75049 | 91483 | 31530781 |
Atrial flutter | 125.48 | 11.50 | 164 | 74916 | 14491 | 31607773 |
Pyrexia | 121.22 | 11.50 | 346 | 74734 | 303494 | 31318770 |
Blood thyroid stimulating hormone increased | 108.93 | 11.50 | 80 | 75000 | 3457 | 31618807 |
Lung disorder | 104.21 | 11.50 | 234 | 74846 | 32078 | 31590186 |
Cardiac failure chronic | 101.70 | 11.50 | 105 | 74975 | 7198 | 31615066 |
Acute respiratory distress syndrome | 100.49 | 11.50 | 196 | 74884 | 24344 | 31597920 |
Sinus bradycardia | 96.92 | 11.50 | 131 | 74949 | 11956 | 31610308 |
Appendicitis | 96.13 | 11.50 | 127 | 74953 | 11338 | 31610926 |
Arthralgia | 96.07 | 11.50 | 131 | 74949 | 151293 | 31470971 |
Cardiac arrest | 93.29 | 11.50 | 438 | 74642 | 88624 | 31533640 |
Thyroid disorder | 93.06 | 11.50 | 68 | 75012 | 2915 | 31619349 |
Myxoedema coma | 92.49 | 11.50 | 32 | 75048 | 250 | 31622014 |
Arrhythmia | 91.91 | 11.50 | 226 | 74854 | 32851 | 31589413 |
Febrile neutropenia | 91.69 | 11.50 | 92 | 74988 | 121757 | 31500507 |
Atrioventricular block | 90.92 | 11.50 | 99 | 74981 | 7216 | 31615048 |
Syncope | 88.54 | 11.50 | 418 | 74662 | 84764 | 31537500 |
Organising pneumonia | 87.36 | 11.50 | 85 | 74995 | 5425 | 31616839 |
Renal failure | 86.17 | 11.50 | 543 | 74537 | 122787 | 31499477 |
Atrial tachycardia | 84.43 | 11.50 | 55 | 75025 | 1952 | 31620312 |
Headache | 79.97 | 11.50 | 200 | 74880 | 183452 | 31438812 |
Drug abuse | 77.27 | 11.50 | 57 | 75023 | 87701 | 31534563 |
Diarrhoea | 72.19 | 11.50 | 514 | 74566 | 351895 | 31270369 |
Seizure | 72.02 | 11.50 | 78 | 75002 | 99690 | 31522574 |
N-terminal prohormone brain natriuretic peptide increased | 70.89 | 11.50 | 51 | 75029 | 2133 | 31620131 |
Corneal deposits | 70.45 | 11.50 | 24 | 75056 | 178 | 31622086 |
Cornea verticillata | 68.96 | 11.50 | 17 | 75063 | 29 | 31622235 |
Stress | 68.84 | 11.50 | 170 | 74910 | 24771 | 31597493 |
Hyperkalaemia | 66.99 | 11.50 | 316 | 74764 | 64035 | 31558229 |
Cardiac failure acute | 66.85 | 11.50 | 98 | 74982 | 9643 | 31612621 |
Pericardial haemorrhage | 66.45 | 11.50 | 56 | 75024 | 2961 | 31619303 |
Hyperglobulinaemia | 65.62 | 11.50 | 13 | 75067 | 0 | 31622264 |
Palpitations | 65.07 | 11.50 | 205 | 74875 | 34378 | 31587886 |
Dyspnoea | 64.80 | 11.50 | 1157 | 73923 | 342322 | 31279942 |
Infusion site phlebitis | 64.76 | 11.50 | 17 | 75063 | 42 | 31622222 |
Product dose omission issue | 62.34 | 11.50 | 96 | 74984 | 105490 | 31516774 |
Suicidal ideation | 61.70 | 11.50 | 7 | 75073 | 36399 | 31585865 |
Venous pressure jugular increased | 61.31 | 11.50 | 32 | 75048 | 743 | 31621521 |
Shock haemorrhagic | 60.80 | 11.50 | 96 | 74984 | 10081 | 31612183 |
Rheumatoid arthritis | 58.63 | 11.50 | 20 | 75060 | 47789 | 31574475 |
Anticoagulation drug level increased | 57.80 | 11.50 | 27 | 75053 | 489 | 31621775 |
Cerebral haematoma | 57.28 | 11.50 | 61 | 75019 | 4334 | 31617930 |
Atrioventricular block complete | 57.09 | 11.50 | 85 | 74995 | 8480 | 31613784 |
Nasopharyngitis | 57.07 | 11.50 | 40 | 75040 | 63205 | 31559059 |
Ventricular extrasystoles | 55.69 | 11.50 | 97 | 74983 | 11045 | 31611219 |
Dyspnoea exertional | 54.60 | 11.50 | 209 | 74871 | 38628 | 31583636 |
Pain in extremity | 54.14 | 11.50 | 122 | 74958 | 116081 | 31506183 |
Haematuria | 53.83 | 11.50 | 235 | 74845 | 46079 | 31576185 |
Pericardial effusion | 53.80 | 11.50 | 145 | 74935 | 22278 | 31599986 |
Labelled drug-drug interaction medication error | 53.71 | 11.50 | 105 | 74975 | 13058 | 31609206 |
Malignant neoplasm progression | 53.49 | 11.50 | 65 | 75015 | 78933 | 31543331 |
Neutropenia | 53.48 | 11.50 | 163 | 74917 | 140201 | 31482063 |
BRASH syndrome | 52.73 | 11.50 | 22 | 75058 | 300 | 31621964 |
Neutrophil count decreased | 52.56 | 11.50 | 22 | 75058 | 46372 | 31575892 |
Anhedonia | 51.25 | 11.50 | 75 | 75005 | 7367 | 31614897 |
Rash | 50.37 | 11.50 | 276 | 74804 | 201210 | 31421054 |
Gastrointestinal haemorrhage | 47.73 | 11.50 | 347 | 74733 | 82202 | 31540062 |
Sinus node dysfunction | 47.55 | 11.50 | 52 | 75028 | 3808 | 31618456 |
Cardioactive drug level increased | 47.46 | 11.50 | 36 | 75044 | 1634 | 31620630 |
Asthma | 47.01 | 11.50 | 21 | 75059 | 42590 | 31579674 |
Jugular vein distension | 46.34 | 11.50 | 25 | 75055 | 622 | 31621642 |
Tachycardia induced cardiomyopathy | 45.40 | 11.50 | 15 | 75065 | 100 | 31622164 |
Thyroxine increased | 44.80 | 11.50 | 14 | 75066 | 76 | 31622188 |
Exercise tolerance decreased | 44.40 | 11.50 | 55 | 75025 | 4603 | 31617661 |
Atrioventricular block first degree | 44.20 | 11.50 | 61 | 75019 | 5676 | 31616588 |
Thyroxine free increased | 43.57 | 11.50 | 18 | 75062 | 239 | 31622025 |
Phlebitis | 42.88 | 11.50 | 48 | 75032 | 3607 | 31618657 |
Drug-induced liver injury | 42.72 | 11.50 | 141 | 74939 | 24222 | 31598042 |
Hyponatraemia | 42.53 | 11.50 | 310 | 74770 | 73489 | 31548775 |
Rectal haemorrhage | 42.02 | 11.50 | 184 | 74896 | 36120 | 31586144 |
Keratopathy | 41.84 | 11.50 | 21 | 75059 | 448 | 31621816 |
Fatigue | 41.35 | 11.50 | 553 | 74527 | 334653 | 31287611 |
Goitre | 40.80 | 11.50 | 32 | 75048 | 1527 | 31620737 |
Muscle spasms | 40.41 | 11.50 | 62 | 75018 | 68256 | 31554008 |
Coronary artery bypass | 39.98 | 11.50 | 53 | 75027 | 4746 | 31617518 |
Acute respiratory failure | 39.44 | 11.50 | 151 | 74929 | 27904 | 31594360 |
Haematoma | 39.06 | 11.50 | 136 | 74944 | 24003 | 31598261 |
Off label use | 38.91 | 11.50 | 584 | 74496 | 346690 | 31275574 |
Musculoskeletal stiffness | 38.80 | 11.50 | 25 | 75055 | 41300 | 31580964 |
Left ventricular failure | 38.63 | 11.50 | 52 | 75028 | 4725 | 31617539 |
Injection site pain | 38.31 | 11.50 | 17 | 75063 | 34617 | 31587647 |
Pneumonitis | 38.29 | 11.50 | 159 | 74921 | 30493 | 31591771 |
Death | 38.16 | 11.50 | 613 | 74467 | 359956 | 31262308 |
Cardiac tamponade | 37.78 | 11.50 | 52 | 75028 | 4827 | 31617437 |
Therapeutic product effect incomplete | 37.64 | 11.50 | 29 | 75051 | 43667 | 31578597 |
Renal injury | 37.50 | 11.50 | 80 | 75000 | 10585 | 31611679 |
Ascites | 37.39 | 11.50 | 194 | 74886 | 40819 | 31581445 |
Rhabdomyolysis | 37.16 | 11.50 | 268 | 74812 | 63313 | 31558951 |
Subdural haematoma | 37.10 | 11.50 | 114 | 74966 | 18857 | 31603407 |
Orthopnoea | 37.08 | 11.50 | 51 | 75029 | 4730 | 31617534 |
Drug dependence | 36.65 | 11.50 | 5 | 75075 | 22574 | 31599690 |
Deep vein thrombosis | 36.03 | 11.50 | 55 | 75025 | 60681 | 31561583 |
Melaena | 35.91 | 11.50 | 163 | 74917 | 32491 | 31589773 |
Pain | 35.88 | 11.50 | 277 | 74803 | 186482 | 31435782 |
Hepatocellular injury | 35.40 | 11.50 | 122 | 74958 | 21422 | 31600842 |
Pulmonary embolism | 35.39 | 11.50 | 89 | 74991 | 81557 | 31540707 |
White blood cell count decreased | 35.06 | 11.50 | 99 | 74981 | 87299 | 31534965 |
Back pain | 34.93 | 11.50 | 137 | 74943 | 109276 | 31512988 |
Insomnia | 34.77 | 11.50 | 112 | 74968 | 94724 | 31527540 |
Cytomegalovirus infection | 34.62 | 11.50 | 8 | 75072 | 24699 | 31597565 |
Aggression | 34.41 | 11.50 | 23 | 75057 | 37268 | 31584996 |
Cardioversion | 34.10 | 11.50 | 23 | 75057 | 866 | 31621398 |
Renal impairment | 33.95 | 11.50 | 333 | 74747 | 86016 | 31536248 |
Tachyarrhythmia | 33.73 | 11.50 | 40 | 75040 | 3199 | 31619065 |
Coagulopathy | 33.22 | 11.50 | 108 | 74972 | 18407 | 31603857 |
Infusion related reaction | 33.09 | 11.50 | 39 | 75041 | 48016 | 31574248 |
Potentiating drug interaction | 32.98 | 11.50 | 47 | 75033 | 4506 | 31617758 |
Myalgia | 32.12 | 11.50 | 86 | 74994 | 77172 | 31545092 |
Sinusitis | 32.06 | 11.50 | 24 | 75056 | 36672 | 31585592 |
Hypertransaminasaemia | 32.02 | 11.50 | 45 | 75035 | 4259 | 31618005 |
Crepitations | 31.89 | 11.50 | 37 | 75043 | 2891 | 31619373 |
Nodal rhythm | 31.84 | 11.50 | 26 | 75054 | 1315 | 31620949 |
Rales | 31.77 | 11.50 | 66 | 75014 | 8573 | 31613691 |
Platelet count decreased | 31.72 | 11.50 | 144 | 74936 | 110291 | 31511973 |
Stomatitis | 31.71 | 11.50 | 28 | 75052 | 39410 | 31582854 |
Asthenia | 31.52 | 11.50 | 725 | 74355 | 224030 | 31398234 |
Pacemaker generated rhythm | 31.16 | 11.50 | 10 | 75070 | 60 | 31622204 |
Gastrooesophageal reflux disease | 31.10 | 11.50 | 21 | 75059 | 33850 | 31588414 |
Intentional product use issue | 30.92 | 11.50 | 43 | 75037 | 49304 | 31572960 |
Nodal arrhythmia | 30.92 | 11.50 | 21 | 75059 | 800 | 31621464 |
Fear | 30.77 | 11.50 | 71 | 75009 | 9903 | 31612361 |
Gravitational oedema | 30.75 | 11.50 | 19 | 75061 | 614 | 31621650 |
Mitochondrial aspartate aminotransferase increased | 30.50 | 11.50 | 7 | 75073 | 7 | 31622257 |
Pleural effusion | 30.47 | 11.50 | 291 | 74789 | 74629 | 31547635 |
Colitis ulcerative | 30.32 | 11.50 | 4 | 75076 | 18525 | 31603739 |
Bundle branch block left | 30.16 | 11.50 | 50 | 75030 | 5468 | 31616796 |
Disease progression | 29.69 | 11.50 | 112 | 74968 | 90352 | 31531912 |
Respiratory failure | 29.68 | 11.50 | 369 | 74711 | 101080 | 31521184 |
Spontaneous haematoma | 29.57 | 11.50 | 17 | 75063 | 480 | 31621784 |
Long QT syndrome | 29.47 | 11.50 | 32 | 75048 | 2324 | 31619940 |
Nausea | 29.46 | 11.50 | 533 | 74547 | 307414 | 31314850 |
Prothrombin time prolonged | 29.37 | 11.50 | 66 | 75014 | 9046 | 31613218 |
Anticoagulation drug level above therapeutic | 29.29 | 11.50 | 29 | 75051 | 1890 | 31620374 |
Activated partial thromboplastin time prolonged | 29.27 | 11.50 | 62 | 75018 | 8163 | 31614101 |
Optic neuropathy | 29.06 | 11.50 | 28 | 75052 | 1765 | 31620499 |
Chills | 29.00 | 11.50 | 85 | 74995 | 74065 | 31548199 |
Prostate cancer | 28.69 | 11.50 | 28 | 75052 | 37573 | 31584691 |
Cerebral haemorrhage | 28.39 | 11.50 | 153 | 74927 | 32659 | 31589605 |
Traumatic lung injury | 28.09 | 11.50 | 23 | 75057 | 1168 | 31621096 |
Angiodysplasia | 28.00 | 11.50 | 17 | 75063 | 532 | 31621732 |
Hypertension | 27.99 | 11.50 | 183 | 74897 | 127917 | 31494347 |
Herpes zoster | 27.85 | 11.50 | 21 | 75059 | 31972 | 31590292 |
Blood pressure increased | 27.84 | 11.50 | 96 | 74984 | 79537 | 31542727 |
Device inappropriate shock delivery | 27.78 | 11.50 | 8 | 75072 | 31 | 31622233 |
Intraocular haematoma | 27.68 | 11.50 | 7 | 75073 | 14 | 31622250 |
Heparin-induced thrombocytopenia | 27.57 | 11.50 | 47 | 75033 | 5259 | 31617005 |
Depression | 27.54 | 11.50 | 116 | 74964 | 90699 | 31531565 |
Low cardiac output syndrome | 27.50 | 11.50 | 17 | 75063 | 550 | 31621714 |
Blood loss anaemia | 27.25 | 11.50 | 58 | 75022 | 7661 | 31614603 |
Psoriasis | 27.05 | 11.50 | 43 | 75037 | 46676 | 31575588 |
Blood pressure fluctuation | 27.03 | 11.50 | 10 | 75070 | 22726 | 31599538 |
Mucosal inflammation | 27.01 | 11.50 | 25 | 75055 | 34402 | 31587862 |
Hypoaesthesia | 26.73 | 11.50 | 58 | 75022 | 55964 | 31566300 |
Presyncope | 26.64 | 11.50 | 96 | 74984 | 17232 | 31605032 |
Optic ischaemic neuropathy | 26.52 | 11.50 | 28 | 75052 | 1969 | 31620295 |
Myoclonus | 26.36 | 11.50 | 83 | 74997 | 13907 | 31608357 |
Injury | 26.01 | 11.50 | 104 | 74976 | 19605 | 31602659 |
Influenza like illness | 25.83 | 11.50 | 14 | 75066 | 25423 | 31596841 |
Xyphoid retraction | 25.60 | 11.50 | 11 | 75069 | 162 | 31622102 |
Cardiac output decreased | 25.58 | 11.50 | 19 | 75061 | 835 | 31621429 |
Hydrops foetalis | 25.36 | 11.50 | 15 | 75065 | 447 | 31621817 |
Halo vision | 25.36 | 11.50 | 11 | 75069 | 166 | 31622098 |
Accessory cardiac pathway | 25.24 | 11.50 | 5 | 75075 | 0 | 31622264 |
Myelosuppression | 24.95 | 11.50 | 3 | 75077 | 14917 | 31607347 |
Sedation | 24.92 | 11.50 | 7 | 75073 | 18958 | 31603306 |
Acute pulmonary oedema | 24.79 | 11.50 | 53 | 75027 | 7023 | 31615241 |
Diaphragmatic paralysis | 24.75 | 11.50 | 15 | 75065 | 468 | 31621796 |
Pancreatitis | 24.66 | 11.50 | 29 | 75051 | 35742 | 31586522 |
Pruritus | 24.31 | 11.50 | 185 | 74895 | 124982 | 31497282 |
Haemodynamic instability | 24.24 | 11.50 | 59 | 75021 | 8516 | 31613748 |
Haemothorax | 24.20 | 11.50 | 36 | 75044 | 3588 | 31618676 |
Platelet distribution width increased | 24.19 | 11.50 | 10 | 75070 | 133 | 31622131 |
Thyroid function test abnormal | 24.18 | 11.50 | 17 | 75063 | 685 | 31621579 |
Dissociation | 24.17 | 11.50 | 22 | 75058 | 1290 | 31620974 |
Antiacetylcholine receptor antibody positive | 24.13 | 11.50 | 8 | 75072 | 54 | 31622210 |
Joint swelling | 24.13 | 11.50 | 57 | 75023 | 53374 | 31568890 |
Cardiac murmur | 24.09 | 11.50 | 51 | 75029 | 6711 | 31615553 |
Urinary tract infection | 24.04 | 11.50 | 97 | 74983 | 76772 | 31545492 |
Hypersensitivity | 23.97 | 11.50 | 61 | 75019 | 55682 | 31566582 |
International normalised ratio abnormal | 23.92 | 11.50 | 33 | 75047 | 3069 | 31619195 |
Glomerular filtration rate decreased | 23.85 | 11.50 | 72 | 75008 | 11793 | 31610471 |
Therapeutic product effect decreased | 23.60 | 11.50 | 24 | 75056 | 31598 | 31590666 |
Fall | 23.55 | 11.50 | 592 | 74488 | 185497 | 31436767 |
Migraine | 23.35 | 11.50 | 3 | 75077 | 14177 | 31608087 |
Puncture site haematoma | 23.29 | 11.50 | 10 | 75070 | 147 | 31622117 |
Blood glucose increased | 23.18 | 11.50 | 71 | 75009 | 61012 | 31561252 |
Periorbital haemorrhage | 22.98 | 11.50 | 9 | 75071 | 103 | 31622161 |
Toxic goitre | 22.90 | 11.50 | 5 | 75075 | 3 | 31622261 |
Tachycardia foetal | 22.74 | 11.50 | 13 | 75067 | 363 | 31621901 |
Left atrial enlargement | 22.48 | 11.50 | 17 | 75063 | 768 | 31621496 |
Nephrolithiasis | 22.47 | 11.50 | 19 | 75061 | 27320 | 31594944 |
Femoral artery aneurysm | 22.41 | 11.50 | 10 | 75070 | 162 | 31622102 |
Atrial thrombosis | 22.41 | 11.50 | 26 | 75054 | 2031 | 31620233 |
Blood phosphorus increased | 22.37 | 11.50 | 39 | 75041 | 4443 | 31617821 |
Urine iodine increased | 22.31 | 11.50 | 5 | 75075 | 4 | 31622260 |
Blood creatinine increased | 22.30 | 11.50 | 315 | 74765 | 88763 | 31533501 |
Arteriosclerotic gangrene | 22.23 | 11.50 | 8 | 75072 | 71 | 31622193 |
Plasma cell myeloma | 21.96 | 11.50 | 65 | 75015 | 56466 | 31565798 |
Cardiorenal syndrome | 21.93 | 11.50 | 16 | 75064 | 684 | 31621580 |
Cholestatic liver injury | 21.80 | 11.50 | 25 | 75055 | 1929 | 31620335 |
Iodine uptake abnormal | 21.79 | 11.50 | 5 | 75075 | 5 | 31622259 |
Cardiac ventricular disorder | 21.78 | 11.50 | 11 | 75069 | 238 | 31622026 |
Urticaria | 21.72 | 11.50 | 67 | 75013 | 57450 | 31564814 |
Gastrointestinal angiodysplasia | 21.64 | 11.50 | 15 | 75065 | 591 | 31621673 |
Lymphocyte count decreased | 21.51 | 11.50 | 11 | 75069 | 20638 | 31601626 |
Neonatal pneumonia | 21.36 | 11.50 | 9 | 75071 | 126 | 31622138 |
Device pacing issue | 21.31 | 11.50 | 6 | 75074 | 21 | 31622243 |
Diabetes mellitus | 21.19 | 11.50 | 43 | 75037 | 42513 | 31579751 |
Ischaemic stroke | 21.16 | 11.50 | 88 | 74992 | 16883 | 31605381 |
Neuropathy peripheral | 20.90 | 11.50 | 100 | 74980 | 75549 | 31546715 |
Hyperglycaemia | 20.71 | 11.50 | 34 | 75046 | 36442 | 31585822 |
Orthostatic hypertension | 20.63 | 11.50 | 11 | 75069 | 267 | 31621997 |
Oedema peripheral | 20.55 | 11.50 | 370 | 74710 | 109469 | 31512795 |
Subarachnoid haemorrhage | 20.34 | 11.50 | 62 | 75018 | 10209 | 31612055 |
Glomerular filtration rate | 20.17 | 11.50 | 8 | 75072 | 95 | 31622169 |
Anuria | 20.15 | 11.50 | 60 | 75020 | 9754 | 31612510 |
Cardio-respiratory arrest | 20.08 | 11.50 | 199 | 74881 | 51527 | 31570737 |
Sinoatrial block | 20.04 | 11.50 | 13 | 75067 | 458 | 31621806 |
Left ventricular dysfunction | 19.97 | 11.50 | 58 | 75022 | 9299 | 31612965 |
Neonatal hypotension | 19.94 | 11.50 | 9 | 75071 | 150 | 31622114 |
Lupus pneumonitis | 19.87 | 11.50 | 7 | 75073 | 58 | 31622206 |
General physical health deterioration | 19.80 | 11.50 | 378 | 74702 | 113057 | 31509207 |
Bundle branch block | 19.68 | 11.50 | 16 | 75064 | 804 | 31621460 |
Papilloedema | 19.67 | 11.50 | 27 | 75053 | 2499 | 31619765 |
Anaemia macrocytic | 19.64 | 11.50 | 29 | 75051 | 2871 | 31619393 |
Drug withdrawal syndrome | 19.51 | 11.50 | 10 | 75070 | 18740 | 31603524 |
Respiratory distress | 19.34 | 11.50 | 141 | 74939 | 33412 | 31588852 |
Ischaemic cardiomyopathy | 19.32 | 11.50 | 43 | 75037 | 5854 | 31616410 |
Dyspnoea at rest | 19.31 | 11.50 | 32 | 75048 | 3499 | 31618765 |
Supraventricular tachycardia | 19.28 | 11.50 | 61 | 75019 | 10246 | 31612018 |
Lymphoid tissue hyperplasia | 19.27 | 11.50 | 7 | 75073 | 64 | 31622200 |
Conjunctival haemorrhage | 19.26 | 11.50 | 28 | 75052 | 2734 | 31619530 |
Swelling | 19.24 | 11.50 | 37 | 75043 | 37321 | 31584943 |
Normocytic anaemia | 19.22 | 11.50 | 24 | 75056 | 2025 | 31620239 |
Eosinophilia | 19.15 | 11.50 | 107 | 74973 | 23146 | 31599118 |
Upper respiratory tract infection | 19.07 | 11.50 | 25 | 75055 | 29397 | 31592867 |
Supine hypertension | 19.03 | 11.50 | 11 | 75069 | 314 | 31621950 |
Aerophagia | 18.99 | 11.50 | 6 | 75074 | 34 | 31622230 |
Depressed mood | 18.85 | 11.50 | 9 | 75071 | 17566 | 31604698 |
Product use issue | 18.79 | 11.50 | 70 | 75010 | 56689 | 31565575 |
Alopecia | 18.77 | 11.50 | 13 | 75067 | 20682 | 31601582 |
Pulmonary oedema | 18.65 | 11.50 | 174 | 74906 | 44328 | 31577936 |
Porphyria acute | 18.56 | 11.50 | 11 | 75069 | 329 | 31621935 |
Drug resistance | 18.43 | 11.50 | 17 | 75063 | 23436 | 31598828 |
Pseudolymphoma | 18.15 | 11.50 | 13 | 75067 | 540 | 31621724 |
Foetal exposure during pregnancy | 18.14 | 11.50 | 44 | 75036 | 40832 | 31581432 |
Withdrawal syndrome | 18.08 | 11.50 | 3 | 75077 | 11714 | 31610550 |
Coma uraemic | 18.03 | 11.50 | 6 | 75074 | 41 | 31622223 |
Iodine overload | 17.96 | 11.50 | 4 | 75076 | 3 | 31622261 |
Osteonecrosis of jaw | 17.92 | 11.50 | 9 | 75071 | 17062 | 31605202 |
Tumour lysis syndrome | 17.90 | 11.50 | 7 | 75073 | 15378 | 31606886 |
Abnormal behaviour | 17.88 | 11.50 | 18 | 75062 | 23810 | 31598454 |
Dyspepsia | 17.87 | 11.50 | 31 | 75049 | 32522 | 31589742 |
Ecchymosis | 17.83 | 11.50 | 44 | 75036 | 6406 | 31615858 |
Rhinorrhoea | 17.71 | 11.50 | 17 | 75063 | 22995 | 31599269 |
Musculoskeletal pain | 17.69 | 11.50 | 27 | 75053 | 29801 | 31592463 |
Accidental exposure to product | 17.62 | 11.50 | 3 | 75077 | 11492 | 31610772 |
Blood thyroid stimulating hormone decreased | 17.57 | 11.50 | 22 | 75058 | 1861 | 31620403 |
Neuroleptic malignant syndrome | 17.55 | 11.50 | 9 | 75071 | 16860 | 31605404 |
Irritability | 17.51 | 11.50 | 17 | 75063 | 22872 | 31599392 |
Oesophageal infection | 17.47 | 11.50 | 10 | 75070 | 280 | 31621984 |
Secondary hyperthyroidism | 17.43 | 11.50 | 4 | 75076 | 4 | 31622260 |
Pemphigoid | 17.39 | 11.50 | 51 | 75029 | 8220 | 31614044 |
Loss of personal independence in daily activities | 17.37 | 11.50 | 25 | 75055 | 28263 | 31594001 |
Lower respiratory tract infection | 17.29 | 11.50 | 25 | 75055 | 28212 | 31594052 |
Orthostatic hypotension | 17.29 | 11.50 | 107 | 74973 | 24012 | 31598252 |
Haemoptysis | 17.27 | 11.50 | 133 | 74947 | 32056 | 31590208 |
Oropharyngeal pain | 17.27 | 11.50 | 30 | 75050 | 31453 | 31590811 |
Cholestasis | 17.20 | 11.50 | 110 | 74970 | 24965 | 31597299 |
Influenza | 17.19 | 11.50 | 51 | 75029 | 44274 | 31577990 |
Muscle haemorrhage | 17.00 | 11.50 | 30 | 75050 | 3450 | 31618814 |
Vascular purpura | 16.89 | 11.50 | 19 | 75061 | 1435 | 31620829 |
Abdominal discomfort | 16.80 | 11.50 | 64 | 75016 | 51503 | 31570761 |
Serotonin syndrome | 16.76 | 11.50 | 12 | 75068 | 18761 | 31603503 |
Electrocardiogram PR prolongation | 16.75 | 11.50 | 14 | 75066 | 732 | 31621532 |
Systemic inflammatory response syndrome | 16.71 | 11.50 | 42 | 75038 | 6183 | 31616081 |
Bladder cancer | 16.64 | 11.50 | 7 | 75073 | 14718 | 31607546 |
COVID-19 | 16.62 | 11.50 | 70 | 75010 | 54751 | 31567513 |
Decreased appetite | 16.62 | 11.50 | 259 | 74821 | 152958 | 31469306 |
Cardiac pacemaker insertion | 16.61 | 11.50 | 26 | 75054 | 2709 | 31619555 |
Ilium fracture | 16.55 | 11.50 | 7 | 75073 | 99 | 31622165 |
Scrotal haematocoele | 16.51 | 11.50 | 5 | 75075 | 24 | 31622240 |
Ejection fraction abnormal | 16.44 | 11.50 | 15 | 75065 | 882 | 31621382 |
Haemorrhage intracranial | 16.34 | 11.50 | 75 | 75005 | 15013 | 31607251 |
Thyroiditis acute | 16.30 | 11.50 | 7 | 75073 | 103 | 31622161 |
Colitis | 16.23 | 11.50 | 35 | 75045 | 33852 | 31588412 |
Product quality issue | 16.17 | 11.50 | 9 | 75071 | 16102 | 31606162 |
Dry skin | 16.16 | 11.50 | 22 | 75058 | 25459 | 31596805 |
Injection site erythema | 16.15 | 11.50 | 7 | 75073 | 14455 | 31607809 |
Hospitalisation | 16.11 | 11.50 | 62 | 75018 | 49745 | 31572519 |
Cardiac arrest neonatal | 16.02 | 11.50 | 5 | 75075 | 27 | 31622237 |
Epistaxis | 15.97 | 11.50 | 196 | 74884 | 53511 | 31568753 |
Infection | 15.94 | 11.50 | 121 | 74959 | 81810 | 31540454 |
Hepatitis C | 15.80 | 11.50 | 3 | 75077 | 10627 | 31611637 |
Basal cell carcinoma | 15.73 | 11.50 | 12 | 75068 | 18167 | 31604097 |
Heart rate abnormal | 15.73 | 11.50 | 20 | 75060 | 1718 | 31620546 |
Therapeutic response decreased | 15.72 | 11.50 | 24 | 75056 | 26485 | 31595779 |
Hypervolaemia | 15.71 | 11.50 | 85 | 74995 | 18166 | 31604098 |
Dysphagia | 15.49 | 11.50 | 77 | 75003 | 57599 | 31564665 |
Hirsutism | 15.47 | 11.50 | 8 | 75072 | 182 | 31622082 |
Hepatitis fulminant | 15.42 | 11.50 | 30 | 75050 | 3716 | 31618548 |
Oesophageal achalasia | 15.42 | 11.50 | 10 | 75070 | 352 | 31621912 |
Graft versus host disease | 15.42 | 11.50 | 3 | 75077 | 10444 | 31611820 |
Cellulitis | 15.38 | 11.50 | 60 | 75020 | 47958 | 31574306 |
Mitral valve incompetence | 15.38 | 11.50 | 70 | 75010 | 13963 | 31608301 |
Ischaemic hepatitis | 15.36 | 11.50 | 19 | 75061 | 1588 | 31620676 |
Fasting | 15.20 | 11.50 | 4 | 75076 | 10 | 31622254 |
Systemic-pulmonary artery shunt | 15.14 | 11.50 | 3 | 75077 | 0 | 31622264 |
Bone marrow granuloma | 15.14 | 11.50 | 3 | 75077 | 0 | 31622264 |
Angioedema | 15.06 | 11.50 | 36 | 75044 | 33582 | 31588682 |
Thyroxine free decreased | 15.02 | 11.50 | 9 | 75071 | 275 | 31621989 |
Psoriatic arthropathy | 14.94 | 11.50 | 15 | 75065 | 19868 | 31602396 |
Pseudarthrosis | 14.92 | 11.50 | 6 | 75074 | 74 | 31622190 |
Diffuse vasculitis | 14.71 | 11.50 | 6 | 75074 | 77 | 31622187 |
Hypophonesis | 14.68 | 11.50 | 4 | 75076 | 12 | 31622252 |
Axonal neuropathy | 14.67 | 11.50 | 15 | 75065 | 1016 | 31621248 |
Abdominal distension | 14.65 | 11.50 | 184 | 74896 | 50500 | 31571764 |
Emotional distress | 14.55 | 11.50 | 70 | 75010 | 14286 | 31607978 |
Deposit eye | 14.46 | 11.50 | 5 | 75075 | 39 | 31622225 |
Non-compaction cardiomyopathy | 14.46 | 11.50 | 5 | 75075 | 39 | 31622225 |
Amaurosis | 14.39 | 11.50 | 12 | 75068 | 625 | 31621639 |
Bradyarrhythmia | 14.29 | 11.50 | 21 | 75059 | 2070 | 31620194 |
Cell death | 14.25 | 11.50 | 21 | 75059 | 2075 | 31620189 |
Lymphadenopathy | 14.23 | 11.50 | 25 | 75055 | 26096 | 31596168 |
Conduction disorder | 14.22 | 11.50 | 20 | 75060 | 1894 | 31620370 |
Bone marrow failure | 14.20 | 11.50 | 28 | 75052 | 27980 | 31594284 |
Supraventricular extrasystoles | 14.20 | 11.50 | 26 | 75054 | 3078 | 31619186 |
Myopathy | 14.11 | 11.50 | 57 | 75023 | 10795 | 31611469 |
Injection site reaction | 14.06 | 11.50 | 5 | 75075 | 11646 | 31610618 |
Arthropathy | 14.05 | 11.50 | 22 | 75058 | 24029 | 31598235 |
Hepatitis cholestatic | 14.02 | 11.50 | 43 | 75037 | 7103 | 31615161 |
Osteoporosis | 13.93 | 11.50 | 5 | 75075 | 11578 | 31610686 |
Erectile dysfunction | 13.90 | 11.50 | 15 | 75065 | 19220 | 31603044 |
Tri-iodothyronine decreased | 13.83 | 11.50 | 5 | 75075 | 45 | 31622219 |
Pericarditis fungal | 13.79 | 11.50 | 7 | 75073 | 153 | 31622111 |
Myxoedema | 13.79 | 11.50 | 4 | 75076 | 16 | 31622248 |
Paranoia | 13.67 | 11.50 | 4 | 75076 | 10551 | 31611713 |
Cardiac dysfunction | 13.64 | 11.50 | 20 | 75060 | 1967 | 31620297 |
Chronotropic incompetence | 13.60 | 11.50 | 4 | 75076 | 17 | 31622247 |
Osteonecrosis | 13.58 | 11.50 | 8 | 75072 | 13876 | 31608388 |
Thyrotoxic periodic paralysis | 13.52 | 11.50 | 6 | 75074 | 96 | 31622168 |
Hepatic cirrhosis | 13.49 | 11.50 | 73 | 75007 | 15601 | 31606663 |
Mediastinal haemorrhage | 13.46 | 11.50 | 5 | 75075 | 49 | 31622215 |
Lung infiltration | 13.44 | 11.50 | 61 | 75019 | 12152 | 31610112 |
Leukopenia | 13.44 | 11.50 | 81 | 74999 | 57747 | 31564517 |
Arteriosclerotic retinopathy | 13.42 | 11.50 | 4 | 75076 | 18 | 31622246 |
Neoplasm progression | 13.37 | 11.50 | 17 | 75063 | 20255 | 31602009 |
Localised infection | 13.31 | 11.50 | 10 | 75070 | 15255 | 31607009 |
Fascial rupture | 13.24 | 11.50 | 4 | 75076 | 19 | 31622245 |
Cardiothoracic ratio increased | 13.24 | 11.50 | 4 | 75076 | 19 | 31622245 |
Abdominal pain upper | 13.18 | 11.50 | 93 | 74987 | 63909 | 31558355 |
Alveolitis necrotising | 13.07 | 11.50 | 4 | 75076 | 20 | 31622244 |
Subdural haematoma evacuation | 13.07 | 11.50 | 4 | 75076 | 20 | 31622244 |
Toxic nodular goitre | 13.07 | 11.50 | 4 | 75076 | 20 | 31622244 |
Myoglobin urine present | 13.05 | 11.50 | 7 | 75073 | 172 | 31622092 |
Traumatic haemothorax | 13.05 | 11.50 | 8 | 75072 | 255 | 31622009 |
Bone pain | 13.00 | 11.50 | 16 | 75064 | 19335 | 31602929 |
Acute lung injury | 12.99 | 11.50 | 16 | 75064 | 1331 | 31620933 |
Vomiting | 12.96 | 11.50 | 418 | 74662 | 223555 | 31398709 |
Adrenal haematoma | 12.95 | 11.50 | 5 | 75075 | 55 | 31622209 |
Flushing | 12.92 | 11.50 | 33 | 75047 | 30095 | 31592169 |
Progressive multifocal leukoencephalopathy | 12.87 | 11.50 | 3 | 75077 | 9210 | 31613054 |
Generalised tonic-clonic seizure | 12.85 | 11.50 | 17 | 75063 | 19914 | 31602350 |
Nephroangiosclerosis | 12.84 | 11.50 | 7 | 75073 | 178 | 31622086 |
Pulseless electrical activity | 12.76 | 11.50 | 40 | 75040 | 6687 | 31615577 |
Ventricular dysfunction | 12.65 | 11.50 | 27 | 75053 | 3573 | 31618691 |
Linear IgA disease | 12.63 | 11.50 | 17 | 75063 | 1545 | 31620719 |
Ulcer haemorrhage | 12.62 | 11.50 | 22 | 75058 | 2505 | 31619759 |
Viral infection | 12.62 | 11.50 | 11 | 75069 | 15582 | 31606682 |
Drug intolerance | 12.56 | 11.50 | 72 | 75008 | 51961 | 31570303 |
Tri-iodothyronine free decreased | 12.56 | 11.50 | 5 | 75075 | 60 | 31622204 |
Depressed level of consciousness | 12.51 | 11.50 | 48 | 75032 | 38553 | 31583711 |
Hyponatraemic syndrome | 12.49 | 11.50 | 7 | 75073 | 188 | 31622076 |
Type 2 diabetes mellitus | 12.49 | 11.50 | 10 | 75070 | 14774 | 31607490 |
Pulmonary vascular resistance abnormality | 12.48 | 11.50 | 5 | 75075 | 61 | 31622203 |
Prothrombin time shortened | 12.46 | 11.50 | 16 | 75064 | 1388 | 31620876 |
Palmar-plantar erythrodysaesthesia syndrome | 12.43 | 11.50 | 11 | 75069 | 15472 | 31606792 |
Oedema genital | 12.39 | 11.50 | 9 | 75071 | 382 | 31621882 |
Therapeutic drug monitoring analysis not performed | 12.35 | 11.50 | 10 | 75070 | 500 | 31621764 |
Blood creatine increased | 12.28 | 11.50 | 31 | 75049 | 4577 | 31617687 |
Hypersensitivity pneumonitis | 12.25 | 11.50 | 16 | 75064 | 1412 | 31620852 |
Tri-iodothyronine increased | 12.20 | 11.50 | 5 | 75075 | 65 | 31622199 |
Proteinuria | 12.20 | 11.50 | 13 | 75067 | 16750 | 31605514 |
Dry gangrene | 12.07 | 11.50 | 9 | 75071 | 398 | 31621866 |
Electrocardiogram low voltage | 12.06 | 11.50 | 4 | 75076 | 27 | 31622237 |
Sinus arrhythmia | 12.06 | 11.50 | 12 | 75068 | 787 | 31621477 |
Cardiac disorder | 12.04 | 11.50 | 144 | 74936 | 39070 | 31583194 |
Iron deficiency anaemia | 12.04 | 11.50 | 49 | 75031 | 9310 | 31612954 |
Psychomotor hyperactivity | 12.01 | 11.50 | 3 | 75077 | 8784 | 31613480 |
Atrial conduction time prolongation | 11.86 | 11.50 | 3 | 75077 | 6 | 31622258 |
Electrocardiogram QRS complex prolonged | 11.85 | 11.50 | 29 | 75051 | 4200 | 31618064 |
Failure to suspend medication | 11.82 | 11.50 | 9 | 75071 | 411 | 31621853 |
Arthritis | 11.74 | 11.50 | 30 | 75050 | 27355 | 31594909 |
Septic shock | 11.71 | 11.50 | 221 | 74859 | 65937 | 31556327 |
Neuromyopathy | 11.71 | 11.50 | 13 | 75067 | 968 | 31621296 |
Wolff-Parkinson-White syndrome | 11.71 | 11.50 | 7 | 75073 | 213 | 31622051 |
Optic nerve infarction | 11.70 | 11.50 | 4 | 75076 | 30 | 31622234 |
Vascular pseudoaneurysm | 11.62 | 11.50 | 19 | 75061 | 2054 | 31620210 |
Epilepsy | 11.58 | 11.50 | 20 | 75060 | 21021 | 31601243 |
Mesenteric artery thrombosis | 11.56 | 11.50 | 9 | 75071 | 425 | 31621839 |
Arterial haemorrhage | 11.51 | 11.50 | 12 | 75068 | 832 | 31621432 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hyperthyroidism | 2314.54 | 11.20 | 958 | 114422 | 19133 | 70793931 |
Drug interaction | 1534.55 | 11.20 | 2439 | 112941 | 379002 | 70434062 |
Atrial fibrillation | 1389.62 | 11.20 | 1602 | 113778 | 182746 | 70630318 |
Bradycardia | 1196.79 | 11.20 | 1231 | 114149 | 123384 | 70689680 |
Ventricular tachycardia | 1072.27 | 11.20 | 693 | 114687 | 35730 | 70777334 |
Torsade de pointes | 1017.56 | 11.20 | 525 | 114855 | 17591 | 70795473 |
Pulmonary toxicity | 1001.97 | 11.20 | 442 | 114938 | 10356 | 70802708 |
Electrocardiogram QT prolonged | 936.31 | 11.20 | 898 | 114482 | 82619 | 70730445 |
Interstitial lung disease | 813.13 | 11.20 | 925 | 114455 | 103760 | 70709304 |
Cardiac failure | 734.92 | 11.20 | 1030 | 114350 | 142511 | 70670553 |
Acute kidney injury | 554.44 | 11.20 | 1862 | 113518 | 472762 | 70340302 |
Thyroiditis | 503.74 | 11.20 | 204 | 115176 | 3832 | 70809232 |
Hypothyroidism | 499.19 | 11.20 | 485 | 114895 | 45270 | 70767794 |
Cardiogenic shock | 473.39 | 11.20 | 425 | 114955 | 35882 | 70777182 |
International normalised ratio increased | 473.10 | 11.20 | 619 | 114761 | 80107 | 70732957 |
Ventricular fibrillation | 472.24 | 11.20 | 375 | 115005 | 26736 | 70786328 |
Myxoedema coma | 388.16 | 11.20 | 109 | 115271 | 599 | 70812465 |
Rheumatoid arthritis | 331.65 | 11.20 | 42 | 115338 | 291763 | 70521301 |
Sinus bradycardia | 300.94 | 11.20 | 273 | 115107 | 23350 | 70789714 |
Arthralgia | 294.51 | 11.20 | 233 | 115147 | 503157 | 70309907 |
Hypotension | 287.03 | 11.20 | 1359 | 114021 | 403022 | 70410042 |
Pulmonary fibrosis | 284.50 | 11.20 | 314 | 115066 | 33996 | 70779068 |
Headache | 265.75 | 11.20 | 333 | 115047 | 580072 | 70232992 |
Syncope | 264.75 | 11.20 | 727 | 114653 | 164982 | 70648082 |
Multiple organ dysfunction syndrome | 262.52 | 11.20 | 559 | 114821 | 107956 | 70705108 |
Cardiac failure congestive | 255.01 | 11.20 | 632 | 114748 | 134825 | 70678239 |
Cardiac arrest | 246.21 | 11.20 | 692 | 114688 | 159142 | 70653922 |
Hyperkalaemia | 242.88 | 11.20 | 536 | 114844 | 106055 | 70707009 |
Pain | 242.47 | 11.20 | 407 | 114973 | 628409 | 70184655 |
Atrial flutter | 237.77 | 11.20 | 224 | 115156 | 20103 | 70792961 |
Renal failure | 235.98 | 11.20 | 760 | 114620 | 188310 | 70624754 |
Ventricular arrhythmia | 222.92 | 11.20 | 146 | 115234 | 7684 | 70805380 |
Thyrotoxic crisis | 217.74 | 11.20 | 80 | 115300 | 1140 | 70811924 |
Joint swelling | 207.95 | 11.20 | 76 | 115304 | 253135 | 70559929 |
Alopecia | 191.53 | 11.20 | 44 | 115336 | 198446 | 70614618 |
Hyponatraemia | 191.14 | 11.20 | 634 | 114746 | 159453 | 70653611 |
Gastrointestinal haemorrhage | 185.76 | 11.20 | 568 | 114812 | 136840 | 70676224 |
Haematoma | 181.52 | 11.20 | 301 | 115079 | 48117 | 70764947 |
Nasopharyngitis | 180.23 | 11.20 | 68 | 115312 | 222138 | 70590926 |
Tachyarrhythmia | 179.25 | 11.20 | 118 | 115262 | 6264 | 70806800 |
Arrhythmia | 179.11 | 11.20 | 325 | 115055 | 55818 | 70757246 |
Appendicolith | 176.72 | 11.20 | 112 | 115268 | 5568 | 70807496 |
Pulmonary alveolar haemorrhage | 175.33 | 11.20 | 141 | 115239 | 10228 | 70802836 |
Shock haemorrhagic | 173.57 | 11.20 | 179 | 115201 | 17927 | 70795137 |
Synovitis | 166.94 | 11.20 | 11 | 115369 | 129217 | 70683847 |
Sinus node dysfunction | 162.19 | 11.20 | 116 | 115264 | 7053 | 70806011 |
Rash | 161.48 | 11.20 | 371 | 115009 | 510191 | 70302873 |
Drug intolerance | 161.07 | 11.20 | 83 | 115297 | 225604 | 70587460 |
Infusion related reaction | 160.94 | 11.20 | 60 | 115320 | 197474 | 70615590 |
Sinusitis | 158.32 | 11.20 | 40 | 115340 | 169155 | 70643909 |
Therapeutic product effect decreased | 156.62 | 11.20 | 23 | 115357 | 142995 | 70670069 |
Atrioventricular block | 156.44 | 11.20 | 144 | 115236 | 12544 | 70800520 |
Acute respiratory distress syndrome | 154.01 | 11.20 | 256 | 115124 | 40998 | 70772066 |
Arthropathy | 153.52 | 11.20 | 29 | 115351 | 150028 | 70663036 |
Labelled drug-drug interaction medication error | 145.86 | 11.20 | 188 | 115192 | 23939 | 70789125 |
Lung disorder | 143.30 | 11.20 | 336 | 115044 | 69148 | 70743916 |
Pain in extremity | 142.86 | 11.20 | 195 | 115185 | 327887 | 70485177 |
Blood thyroid stimulating hormone increased | 140.61 | 11.20 | 114 | 115266 | 8365 | 70804699 |
Pyrexia | 140.10 | 11.20 | 512 | 114868 | 606440 | 70206624 |
Fatigue | 138.59 | 11.20 | 782 | 114598 | 823537 | 69989527 |
Hypersensitivity | 137.09 | 11.20 | 104 | 115276 | 229708 | 70583356 |
Swelling | 136.51 | 11.20 | 68 | 115312 | 188471 | 70624593 |
Completed suicide | 131.43 | 11.20 | 106 | 115274 | 227029 | 70586035 |
Rhabdomyolysis | 128.56 | 11.20 | 395 | 114985 | 95365 | 70717699 |
Musculoskeletal stiffness | 127.02 | 11.20 | 41 | 115339 | 147719 | 70665345 |
Ventricular extrasystoles | 126.15 | 11.20 | 152 | 115228 | 18074 | 70794990 |
Haematuria | 123.09 | 11.20 | 300 | 115080 | 63273 | 70749791 |
Cerebral haematoma | 121.93 | 11.20 | 99 | 115281 | 7279 | 70805785 |
Organising pneumonia | 121.85 | 11.20 | 113 | 115267 | 9937 | 70803127 |
Melaena | 121.13 | 11.20 | 277 | 115103 | 56078 | 70756986 |
Hand deformity | 119.08 | 11.20 | 5 | 115375 | 86477 | 70726587 |
Atrial tachycardia | 117.35 | 11.20 | 74 | 115306 | 3646 | 70809418 |
Systemic lupus erythematosus | 117.26 | 11.20 | 14 | 115366 | 101888 | 70711176 |
Pemphigus | 113.67 | 11.20 | 5 | 115375 | 83031 | 70730033 |
Cardiac failure chronic | 112.19 | 11.20 | 109 | 115271 | 10160 | 70802904 |
Hyperglobulinaemia | 111.08 | 11.20 | 21 | 115359 | 3 | 70813061 |
Cerebral haemorrhage | 108.37 | 11.20 | 258 | 115122 | 53606 | 70759458 |
Glossodynia | 107.02 | 11.20 | 9 | 115371 | 86478 | 70726586 |
Long QT syndrome | 106.50 | 11.20 | 80 | 115300 | 5247 | 70807817 |
Stomatitis | 106.39 | 11.20 | 38 | 115342 | 128473 | 70684591 |
Rectal haemorrhage | 106.14 | 11.20 | 290 | 115090 | 65541 | 70747523 |
Pericardial haemorrhage | 105.71 | 11.20 | 73 | 115307 | 4195 | 70808869 |
Infusion site phlebitis | 105.23 | 11.20 | 28 | 115352 | 121 | 70812943 |
Maternal exposure during pregnancy | 104.59 | 11.20 | 29 | 115351 | 115316 | 70697748 |
Atrioventricular block complete | 102.57 | 11.20 | 125 | 115255 | 15038 | 70798026 |
Injection site pain | 102.22 | 11.20 | 32 | 115348 | 117587 | 70695477 |
Diarrhoea | 101.90 | 11.20 | 802 | 114578 | 782539 | 70030525 |
Orthopnoea | 101.17 | 11.20 | 99 | 115281 | 9309 | 70803755 |
Abdominal discomfort | 94.97 | 11.20 | 126 | 115254 | 214532 | 70598532 |
Dyspnoea | 93.30 | 11.20 | 1763 | 113617 | 768297 | 70044767 |
Cardioactive drug level increased | 93.14 | 11.20 | 63 | 115317 | 3499 | 70809565 |
Appendicitis | 92.81 | 11.20 | 125 | 115255 | 16608 | 70796456 |
Corneal deposits | 92.01 | 11.20 | 33 | 115347 | 437 | 70812627 |
Febrile neutropenia | 91.34 | 11.20 | 119 | 115261 | 204199 | 70608865 |
Product dose omission issue | 90.86 | 11.20 | 133 | 115247 | 217335 | 70595729 |
Nausea | 90.80 | 11.20 | 918 | 114462 | 851170 | 69961894 |
Cornea verticillata | 90.33 | 11.20 | 24 | 115356 | 103 | 70812961 |
Cardiac failure acute | 90.01 | 11.20 | 126 | 115254 | 17361 | 70795703 |
Hypoaesthesia | 89.83 | 11.20 | 71 | 115309 | 153668 | 70659396 |
Asthma | 89.79 | 11.20 | 42 | 115338 | 120751 | 70692313 |
Respiratory failure | 88.93 | 11.20 | 523 | 114857 | 168212 | 70644852 |
Therapeutic product effect incomplete | 88.63 | 11.20 | 42 | 115338 | 119840 | 70693224 |
Migraine | 88.07 | 11.20 | 8 | 115372 | 72230 | 70740834 |
Back pain | 87.18 | 11.20 | 195 | 115185 | 270957 | 70542107 |
Anaemia | 87.11 | 11.20 | 1021 | 114359 | 402402 | 70410662 |
Renal injury | 85.89 | 11.20 | 118 | 115262 | 15976 | 70797088 |
Ejection fraction decreased | 85.57 | 11.20 | 168 | 115212 | 30594 | 70782470 |
Hepatocellular injury | 83.41 | 11.20 | 212 | 115168 | 45879 | 70767185 |
Cardio-respiratory arrest | 82.80 | 11.20 | 354 | 115026 | 100323 | 70712741 |
Subdural haematoma | 81.49 | 11.20 | 160 | 115220 | 29138 | 70783926 |
Wound | 80.35 | 11.20 | 30 | 115350 | 98702 | 70714362 |
Urticaria | 80.28 | 11.20 | 88 | 115292 | 162961 | 70650103 |
Cholestasis | 79.27 | 11.20 | 213 | 115167 | 47659 | 70765405 |
Anticoagulation drug level increased | 78.17 | 11.20 | 33 | 115347 | 691 | 70812373 |
Product use issue | 76.18 | 11.20 | 109 | 115271 | 179828 | 70633236 |
Acute respiratory failure | 75.41 | 11.20 | 225 | 115155 | 53440 | 70759624 |
Muscle spasms | 74.90 | 11.20 | 84 | 115296 | 153962 | 70659102 |
Coronary artery bypass | 74.56 | 11.20 | 68 | 115312 | 5852 | 70807212 |
Lower respiratory tract infection | 74.24 | 11.20 | 45 | 115335 | 111868 | 70701196 |
Pruritus | 74.04 | 11.20 | 300 | 115080 | 345260 | 70467804 |
Pneumonitis | 73.98 | 11.20 | 226 | 115154 | 54371 | 70758693 |
Respiratory distress | 73.85 | 11.20 | 226 | 115154 | 54424 | 70758640 |
Atrioventricular block first degree | 73.77 | 11.20 | 93 | 115287 | 11580 | 70801484 |
Pleural effusion | 72.70 | 11.20 | 416 | 114964 | 132448 | 70680616 |
Keratopathy | 71.97 | 11.20 | 34 | 115346 | 936 | 70812128 |
Coagulopathy | 70.95 | 11.20 | 163 | 115217 | 33086 | 70779978 |
Lactic acidosis | 70.90 | 11.20 | 250 | 115130 | 64774 | 70748290 |
Mitral valve incompetence | 70.77 | 11.20 | 143 | 115237 | 26585 | 70786479 |
Hypokalaemia | 70.64 | 11.20 | 409 | 114971 | 130779 | 70682285 |
Cardioversion | 69.60 | 11.20 | 42 | 115338 | 1912 | 70811152 |
Off label use | 69.28 | 11.20 | 825 | 114555 | 742235 | 70070829 |
Alveolitis | 69.09 | 11.20 | 54 | 115326 | 3757 | 70809307 |
Injection site erythema | 68.64 | 11.20 | 17 | 115363 | 72907 | 70740157 |
Blood loss anaemia | 68.37 | 11.20 | 100 | 115280 | 14341 | 70798723 |
Renal impairment | 68.14 | 11.20 | 434 | 114946 | 143503 | 70669561 |
Infection | 67.39 | 11.20 | 152 | 115228 | 210633 | 70602431 |
Arthritis | 66.97 | 11.20 | 38 | 115342 | 97942 | 70715122 |
Hypoxia | 66.82 | 11.20 | 315 | 115065 | 93029 | 70720035 |
Ischaemic stroke | 66.77 | 11.20 | 152 | 115228 | 30668 | 70782396 |
Myalgia | 65.97 | 11.20 | 107 | 115273 | 167785 | 70645279 |
Insomnia | 65.69 | 11.20 | 162 | 115218 | 217644 | 70595420 |
Fall | 65.53 | 11.20 | 1050 | 114330 | 443046 | 70370018 |
Pericardial effusion | 65.31 | 11.20 | 182 | 115198 | 41594 | 70771470 |
Fibromyalgia | 65.13 | 11.20 | 3 | 115377 | 47871 | 70765193 |
Coronary artery disease | 63.98 | 11.20 | 236 | 115144 | 62500 | 70750564 |
Anhedonia | 63.81 | 11.20 | 96 | 115284 | 14117 | 70798947 |
Discomfort | 63.74 | 11.20 | 47 | 115333 | 105389 | 70707675 |
Intentional product use issue | 63.49 | 11.20 | 61 | 115319 | 120081 | 70692983 |
Psoriatic arthropathy | 63.14 | 11.20 | 14 | 115366 | 64757 | 70748307 |
Venous pressure jugular increased | 62.26 | 11.20 | 34 | 115346 | 1278 | 70811786 |
Peripheral swelling | 61.60 | 11.20 | 189 | 115191 | 236374 | 70576690 |
Exposure during pregnancy | 61.43 | 11.20 | 33 | 115347 | 87684 | 70725380 |
Gastrooesophageal reflux disease | 60.99 | 11.20 | 36 | 115344 | 90803 | 70722261 |
Drug-induced liver injury | 60.54 | 11.20 | 215 | 115165 | 55898 | 70757166 |
Tachycardia induced cardiomyopathy | 60.26 | 11.20 | 18 | 115362 | 127 | 70812937 |
Cardiac tamponade | 60.00 | 11.20 | 72 | 115308 | 8523 | 70804541 |
Bundle branch block left | 59.69 | 11.20 | 79 | 115301 | 10320 | 70802744 |
Rales | 59.52 | 11.20 | 103 | 115277 | 17032 | 70796032 |
Injection site reaction | 59.50 | 11.20 | 6 | 115374 | 49846 | 70763218 |
Depression | 59.21 | 11.20 | 149 | 115231 | 198825 | 70614239 |
Neutrophil count decreased | 59.15 | 11.20 | 31 | 115349 | 83525 | 70729539 |
Palpitations | 58.77 | 11.20 | 344 | 115036 | 110409 | 70702655 |
Psoriasis | 58.06 | 11.20 | 45 | 115335 | 98388 | 70714676 |
Nodal arrhythmia | 57.90 | 11.20 | 37 | 115343 | 1866 | 70811198 |
Herpes zoster | 56.91 | 11.20 | 34 | 115346 | 85201 | 70727863 |
Arterial haemorrhage | 56.82 | 11.20 | 40 | 115340 | 2371 | 70810693 |
Spontaneous haematoma | 56.74 | 11.20 | 32 | 115348 | 1282 | 70811782 |
Anuria | 56.69 | 11.20 | 109 | 115271 | 19544 | 70793520 |
White blood cell count decreased | 56.59 | 11.20 | 120 | 115260 | 170021 | 70643043 |
Potentiating drug interaction | 56.35 | 11.20 | 68 | 115312 | 8096 | 70804968 |
Nodal rhythm | 56.21 | 11.20 | 43 | 115337 | 2898 | 70810166 |
Left ventricular dysfunction | 56.03 | 11.20 | 103 | 115277 | 17854 | 70795210 |
Drug abuse | 55.85 | 11.20 | 96 | 115284 | 147160 | 70665904 |
N-terminal prohormone brain natriuretic peptide increased | 55.23 | 11.20 | 48 | 115332 | 3876 | 70809188 |
Seizure | 53.94 | 11.20 | 132 | 115248 | 177830 | 70635234 |
Thyroid disorder | 53.85 | 11.20 | 84 | 115296 | 12748 | 70800316 |
Suicidal ideation | 53.59 | 11.20 | 23 | 115357 | 69573 | 70743491 |
Neuromyopathy | 53.50 | 11.20 | 32 | 115348 | 1433 | 70811631 |
Dyspnoea exertional | 53.47 | 11.20 | 261 | 115119 | 78169 | 70734895 |
Subarachnoid haemorrhage | 52.41 | 11.20 | 105 | 115275 | 19399 | 70793665 |
Heparin-induced thrombocytopenia | 52.40 | 11.20 | 69 | 115311 | 8968 | 70804096 |
Abdominal pain upper | 52.32 | 11.20 | 152 | 115228 | 193450 | 70619614 |
Thyroxine increased | 52.27 | 11.20 | 25 | 115355 | 708 | 70812356 |
Chills | 51.68 | 11.20 | 98 | 115282 | 144688 | 70668376 |
Irritable bowel syndrome | 51.61 | 11.20 | 10 | 115370 | 50840 | 70762224 |
Thyroxine free increased | 51.37 | 11.20 | 29 | 115351 | 1164 | 70811900 |
Folliculitis | 51.13 | 11.20 | 5 | 115375 | 42565 | 70770499 |
Ill-defined disorder | 51.06 | 11.20 | 13 | 115367 | 54728 | 70758336 |
Eosinophilia | 51.02 | 11.20 | 163 | 115217 | 40156 | 70772908 |
Pericarditis | 50.88 | 11.20 | 38 | 115342 | 84667 | 70728397 |
Oropharyngeal pain | 50.77 | 11.20 | 49 | 115331 | 96261 | 70716803 |
Activated partial thromboplastin time prolonged | 50.65 | 11.20 | 84 | 115296 | 13421 | 70799643 |
Anticoagulation drug level above therapeutic | 50.47 | 11.20 | 42 | 115338 | 3196 | 70809868 |
Influenza like illness | 49.66 | 11.20 | 22 | 115358 | 65309 | 70747755 |
Left ventricular failure | 49.62 | 11.20 | 66 | 115314 | 8662 | 70804402 |
Ascites | 49.11 | 11.20 | 229 | 115151 | 67318 | 70745746 |
Presyncope | 48.88 | 11.20 | 153 | 115227 | 37285 | 70775779 |
Musculoskeletal pain | 48.73 | 11.20 | 45 | 115335 | 90282 | 70722782 |
Oedema peripheral | 48.55 | 11.20 | 576 | 114804 | 227515 | 70585549 |
General physical health deterioration | 48.47 | 11.20 | 592 | 114788 | 235439 | 70577625 |
Ecchymosis | 48.29 | 11.20 | 85 | 115295 | 14247 | 70798817 |
Blood pressure increased | 48.08 | 11.20 | 152 | 115228 | 188365 | 70624699 |
Septic shock | 47.98 | 11.20 | 330 | 115050 | 111928 | 70701136 |
BRASH syndrome | 46.26 | 11.20 | 22 | 115358 | 615 | 70812449 |
Blood pressure fluctuation | 46.24 | 11.20 | 19 | 115361 | 58993 | 70754071 |
Iodine overload | 46.22 | 11.20 | 9 | 115371 | 3 | 70813061 |
Jugular vein distension | 45.47 | 11.20 | 28 | 115352 | 1322 | 70811742 |
Haemarthrosis | 45.45 | 11.20 | 50 | 115330 | 5389 | 70807675 |
Toxic skin eruption | 45.42 | 11.20 | 101 | 115279 | 20061 | 70793003 |
Drug level increased | 44.84 | 11.20 | 146 | 115234 | 36323 | 70776741 |
Goitre | 44.05 | 11.20 | 48 | 115332 | 5118 | 70807946 |
Malignant neoplasm progression | 43.79 | 11.20 | 82 | 115298 | 121657 | 70691407 |
Sedation | 43.77 | 11.20 | 11 | 115369 | 46720 | 70766344 |
Prothrombin time shortened | 43.47 | 11.20 | 37 | 115343 | 2905 | 70810159 |
Bradyarrhythmia | 43.26 | 11.20 | 42 | 115338 | 3911 | 70809153 |
Haemorrhage | 42.96 | 11.20 | 258 | 115122 | 83557 | 70729507 |
Asthenia | 42.85 | 11.20 | 1010 | 114370 | 456656 | 70356408 |
Muscle haemorrhage | 42.24 | 11.20 | 50 | 115330 | 5834 | 70807230 |
Prothrombin time prolonged | 42.12 | 11.20 | 86 | 115294 | 16104 | 70796960 |
Weight increased | 42.04 | 11.20 | 227 | 115153 | 242104 | 70570960 |
Exercise tolerance decreased | 41.81 | 11.20 | 59 | 115321 | 8189 | 70804875 |
Haemorrhage intracranial | 41.78 | 11.20 | 111 | 115269 | 24666 | 70788398 |
Lymphatic fistula | 41.51 | 11.20 | 22 | 115358 | 778 | 70812286 |
Femoral hernia incarcerated | 41.33 | 11.20 | 22 | 115358 | 785 | 70812279 |
Glomerular filtration rate decreased | 41.28 | 11.20 | 99 | 115281 | 20657 | 70792407 |
Fear | 41.11 | 11.20 | 99 | 115281 | 20712 | 70792352 |
Drug dependence | 40.84 | 11.20 | 6 | 115374 | 37315 | 70775749 |
Device pacing issue | 40.76 | 11.20 | 12 | 115368 | 80 | 70812984 |
Cardiac murmur | 40.70 | 11.20 | 72 | 115308 | 12114 | 70800950 |
Blood creatinine increased | 40.69 | 11.20 | 383 | 114997 | 142618 | 70670446 |
C-reactive protein abnormal | 40.42 | 11.20 | 7 | 115373 | 38572 | 70774492 |
Haemorrhagic stroke | 40.16 | 11.20 | 65 | 115315 | 10177 | 70802887 |
Upper respiratory tract infection | 39.87 | 11.20 | 42 | 115338 | 79232 | 70733832 |
Craniocerebral injury | 39.75 | 11.20 | 43 | 115337 | 4548 | 70808516 |
Blood phosphorus increased | 39.73 | 11.20 | 52 | 115328 | 6718 | 70806346 |
Rhinorrhoea | 39.57 | 11.20 | 30 | 115350 | 66341 | 70746723 |
Low cardiac output syndrome | 39.50 | 11.20 | 22 | 115358 | 860 | 70812204 |
Gravitational oedema | 38.83 | 11.20 | 28 | 115352 | 1724 | 70811340 |
Myocardial infarction | 38.53 | 11.20 | 438 | 114942 | 171207 | 70641857 |
Optic neuropathy | 38.51 | 11.20 | 36 | 115344 | 3197 | 70809867 |
Haematoma muscle | 38.21 | 11.20 | 31 | 115349 | 2276 | 70810788 |
Acute pulmonary oedema | 38.21 | 11.20 | 74 | 115306 | 13338 | 70799726 |
Colitis ulcerative | 38.19 | 11.20 | 5 | 115375 | 33918 | 70779146 |
Toxicity to various agents | 38.11 | 11.20 | 851 | 114529 | 381321 | 70431743 |
Brugada syndrome | 37.09 | 11.20 | 23 | 115357 | 1100 | 70811964 |
Cerebellar syndrome | 36.81 | 11.20 | 44 | 115336 | 5187 | 70807877 |
Electrocardiogram PR prolongation | 36.63 | 11.20 | 25 | 115355 | 1409 | 70811655 |
Blood cholesterol increased | 36.27 | 11.20 | 31 | 115349 | 64573 | 70748491 |
Neutropenia | 36.23 | 11.20 | 257 | 115123 | 256899 | 70556165 |
Haemothorax | 36.21 | 11.20 | 43 | 115337 | 5034 | 70808030 |
Myopathy | 36.18 | 11.20 | 88 | 115292 | 18524 | 70794540 |
Head injury | 36.12 | 11.20 | 130 | 115250 | 34011 | 70779053 |
Optic ischaemic neuropathy | 36.03 | 11.20 | 32 | 115348 | 2660 | 70810404 |
Pancreatic steatosis | 35.74 | 11.20 | 22 | 115358 | 1038 | 70812026 |
Shock | 35.44 | 11.20 | 145 | 115235 | 40280 | 70772784 |
Contraindicated product administered | 35.40 | 11.20 | 107 | 115273 | 134505 | 70678559 |
Cardiac ablation | 35.06 | 11.20 | 28 | 115352 | 2010 | 70811054 |
Blister | 35.03 | 11.20 | 69 | 115311 | 100457 | 70712607 |
Atrial thrombosis | 34.79 | 11.20 | 34 | 115346 | 3191 | 70809873 |
Drug hypersensitivity | 34.73 | 11.20 | 267 | 115113 | 262192 | 70550872 |
Pulmonary oedema | 34.63 | 11.20 | 241 | 115139 | 82037 | 70731027 |
Sinoatrial block | 34.56 | 11.20 | 23 | 115357 | 1243 | 70811821 |
Pacemaker generated rhythm | 34.45 | 11.20 | 10 | 115370 | 63 | 70813001 |
Wound infection pseudomonas | 34.39 | 11.20 | 25 | 115355 | 1559 | 70811505 |
Osteoarthritis | 34.34 | 11.20 | 42 | 115338 | 74105 | 70738959 |
Bone pain | 34.31 | 11.20 | 20 | 115360 | 50802 | 70762262 |
Knee arthroplasty | 34.28 | 11.20 | 7 | 115373 | 34294 | 70778770 |
Pulmonary hypertension | 33.99 | 11.20 | 158 | 115222 | 46378 | 70766686 |
Ischaemic hepatitis | 33.88 | 11.20 | 34 | 115346 | 3295 | 70809769 |
Lung infiltration | 33.59 | 11.20 | 94 | 115286 | 21530 | 70791534 |
Phlebitis | 33.49 | 11.20 | 53 | 115327 | 8141 | 70804923 |
Dyspnoea at rest | 33.42 | 11.20 | 48 | 115332 | 6771 | 70806293 |
Extravasation | 33.30 | 11.20 | 34 | 115346 | 3363 | 70809701 |
Type 2 diabetes mellitus | 33.25 | 11.20 | 15 | 115365 | 44065 | 70768999 |
Hepatitis fulminant | 33.24 | 11.20 | 47 | 115333 | 6534 | 70806530 |
Mitochondrial aspartate aminotransferase increased | 33.12 | 11.20 | 7 | 115373 | 7 | 70813057 |
Hypervolaemia | 32.92 | 11.20 | 140 | 115240 | 39566 | 70773498 |
Haemoptysis | 32.78 | 11.20 | 168 | 115212 | 51284 | 70761780 |
Haemodynamic instability | 32.57 | 11.20 | 76 | 115304 | 15582 | 70797482 |
Cytomegalovirus infection | 32.47 | 11.20 | 12 | 115368 | 39746 | 70773318 |
Cardiac disorder | 32.45 | 11.20 | 186 | 115194 | 59229 | 70753835 |
Cardiac output decreased | 32.29 | 11.20 | 25 | 115355 | 1715 | 70811349 |
Tricuspid valve incompetence | 32.28 | 11.20 | 82 | 115298 | 17735 | 70795329 |
Injection site swelling | 32.07 | 11.20 | 15 | 115365 | 43142 | 70769922 |
Myxoedema | 32.04 | 11.20 | 11 | 115369 | 127 | 70812937 |
Ischaemic cardiomyopathy | 31.91 | 11.20 | 48 | 115332 | 7056 | 70806008 |
Hip arthroplasty | 31.89 | 11.20 | 4 | 115376 | 28036 | 70785028 |
International normalised ratio abnormal | 31.88 | 11.20 | 41 | 115339 | 5206 | 70807858 |
Hypertension | 31.71 | 11.20 | 318 | 115062 | 295715 | 70517349 |
COVID-19 | 31.59 | 11.20 | 79 | 115301 | 105678 | 70707386 |
Angiodysplasia | 31.52 | 11.20 | 19 | 115361 | 863 | 70812201 |
Mobility decreased | 31.50 | 11.20 | 76 | 115304 | 102923 | 70710141 |
Adverse event | 31.27 | 11.20 | 21 | 115359 | 49440 | 70763624 |
Hepatic failure | 31.21 | 11.20 | 180 | 115200 | 57445 | 70755619 |
Swelling face | 31.17 | 11.20 | 34 | 115346 | 63130 | 70749934 |
Lymphocyte count decreased | 31.04 | 11.20 | 16 | 115364 | 43523 | 70769541 |
Red blood cell sedimentation rate increased | 31.00 | 11.20 | 12 | 115368 | 38630 | 70774434 |
Respiratory acidosis | 30.86 | 11.20 | 58 | 115322 | 10223 | 70802841 |
Osteonecrosis of jaw | 30.86 | 11.20 | 14 | 115366 | 40988 | 70772076 |
Acute hepatic failure | 30.68 | 11.20 | 107 | 115273 | 27565 | 70785499 |
Mixed liver injury | 30.64 | 11.20 | 44 | 115336 | 6205 | 70806859 |
Hepatitis acute | 30.40 | 11.20 | 69 | 115311 | 13893 | 70799171 |
Toxic goitre | 30.29 | 11.20 | 7 | 115373 | 14 | 70813050 |
Injection site bruising | 30.20 | 11.20 | 12 | 115368 | 38020 | 70775044 |
Treatment failure | 29.66 | 11.20 | 127 | 115253 | 144015 | 70669049 |
Cardiovascular insufficiency | 29.65 | 11.20 | 29 | 115351 | 2724 | 70810340 |
Xyphoid retraction | 29.61 | 11.20 | 11 | 115369 | 162 | 70812902 |
Pancreatitis | 29.55 | 11.20 | 35 | 115345 | 62633 | 70750431 |
Fungal infection | 29.46 | 11.20 | 12 | 115368 | 37455 | 70775609 |
Anaemia macrocytic | 29.33 | 11.20 | 39 | 115341 | 5116 | 70807948 |
Osteoporosis | 29.29 | 11.20 | 22 | 115358 | 48885 | 70764179 |
Disease progression | 29.28 | 11.20 | 143 | 115237 | 156529 | 70656535 |
Ventricular tachyarrhythmia | 29.08 | 11.20 | 13 | 115367 | 314 | 70812750 |
Feeling hot | 29.01 | 11.20 | 22 | 115358 | 48648 | 70764416 |
Oral herpes | 28.63 | 11.20 | 3 | 115377 | 24183 | 70788881 |
Neck pain | 28.56 | 11.20 | 40 | 115340 | 66617 | 70746447 |
Palmar-plantar erythrodysaesthesia syndrome | 28.56 | 11.20 | 7 | 115373 | 30240 | 70782824 |
Orthostatic hypotension | 28.27 | 11.20 | 162 | 115218 | 51581 | 70761483 |
Throat irritation | 28.26 | 11.20 | 11 | 115369 | 35293 | 70777771 |
Suicide attempt | 28.20 | 11.20 | 54 | 115326 | 79456 | 70733608 |
Loss of personal independence in daily activities | 28.12 | 11.20 | 60 | 115320 | 84850 | 70728214 |
Deep vein thrombosis | 27.97 | 11.20 | 90 | 115290 | 110952 | 70702112 |
Femoral artery aneurysm | 27.95 | 11.20 | 11 | 115369 | 191 | 70812873 |
Intraocular haematoma | 27.81 | 11.20 | 7 | 115373 | 23 | 70813041 |
Platelet distribution width increased | 27.77 | 11.20 | 10 | 115370 | 134 | 70812930 |
Glomerular filtration rate | 27.77 | 11.20 | 10 | 115370 | 134 | 70812930 |
Cholestatic liver injury | 27.60 | 11.20 | 34 | 115346 | 4134 | 70808930 |
Bursitis | 27.59 | 11.20 | 5 | 115375 | 26668 | 70786396 |
Hot flush | 27.58 | 11.20 | 24 | 115356 | 49560 | 70763504 |
Abdominal wall haematoma | 27.52 | 11.20 | 35 | 115345 | 4395 | 70808669 |
Mediastinal haematoma | 27.48 | 11.20 | 11 | 115369 | 200 | 70812864 |
Cataract | 27.40 | 11.20 | 30 | 115350 | 55615 | 70757449 |
Stress | 27.39 | 11.20 | 197 | 115183 | 67769 | 70745295 |
Periorbital haemorrhage | 27.38 | 11.20 | 11 | 115369 | 202 | 70812862 |
Cellulitis | 27.20 | 11.20 | 77 | 115303 | 98851 | 70714213 |
Feeling abnormal | 27.12 | 11.20 | 129 | 115251 | 142190 | 70670874 |
Night sweats | 27.01 | 11.20 | 19 | 115361 | 43665 | 70769399 |
Mouth ulceration | 27.01 | 11.20 | 11 | 115369 | 34338 | 70778726 |
Vomiting | 26.89 | 11.20 | 747 | 114633 | 592364 | 70220700 |
Gastrointestinal angiodysplasia | 26.88 | 11.20 | 18 | 115362 | 983 | 70812081 |
Ilium fracture | 26.85 | 11.20 | 11 | 115369 | 213 | 70812851 |
Cerebellar haematoma | 26.82 | 11.20 | 15 | 115365 | 591 | 70812473 |
Papilloedema | 26.81 | 11.20 | 40 | 115340 | 5838 | 70807226 |
Myelosuppression | 26.54 | 11.20 | 8 | 115372 | 30137 | 70782927 |
Right ventricular failure | 26.33 | 11.20 | 88 | 115292 | 22186 | 70790878 |
Neoplasm progression | 26.26 | 11.20 | 21 | 115359 | 45207 | 70767857 |
Antiacetylcholine receptor antibody positive | 26.25 | 11.20 | 8 | 115372 | 61 | 70813003 |
Traumatic lung injury | 26.18 | 11.20 | 25 | 115355 | 2280 | 70810784 |
Basal cell carcinoma | 26.16 | 11.20 | 11 | 115369 | 33687 | 70779377 |
Acute coronary syndrome | 26.15 | 11.20 | 82 | 115298 | 19997 | 70793067 |
Extrasystoles | 26.10 | 11.20 | 43 | 115337 | 6831 | 70806233 |
Influenza | 26.04 | 11.20 | 96 | 115284 | 113604 | 70699460 |
Impaired healing | 25.95 | 11.20 | 51 | 115329 | 74323 | 70738741 |
Myoclonus | 25.91 | 11.20 | 98 | 115282 | 26257 | 70786807 |
Lower gastrointestinal haemorrhage | 25.89 | 11.20 | 67 | 115313 | 14653 | 70798411 |
Seroma | 25.88 | 11.20 | 24 | 115356 | 2110 | 70810954 |
Puncture site haematoma | 25.88 | 11.20 | 10 | 115370 | 165 | 70812899 |
Epistaxis | 25.84 | 11.20 | 268 | 115112 | 102359 | 70710705 |
Flushing | 25.63 | 11.20 | 60 | 115320 | 82112 | 70730952 |
Cardioactive drug level above therapeutic | 25.56 | 11.20 | 11 | 115369 | 242 | 70812822 |
Memory impairment | 25.55 | 11.20 | 72 | 115308 | 92569 | 70720495 |
Gastrointestinal disorder | 25.49 | 11.20 | 87 | 115293 | 105340 | 70707724 |
Wheezing | 25.37 | 11.20 | 74 | 115306 | 94096 | 70718968 |
Illness | 25.29 | 11.20 | 10 | 115370 | 31781 | 70781283 |
Therapeutic response decreased | 25.12 | 11.20 | 35 | 115345 | 58418 | 70754646 |
Hypertransaminasaemia | 25.06 | 11.20 | 49 | 115331 | 8894 | 70804170 |
Nephrolithiasis | 25.02 | 11.20 | 24 | 115356 | 47299 | 70765765 |
Hypoglycaemia | 24.99 | 11.20 | 249 | 115131 | 94115 | 70718949 |
Arteriosclerotic gangrene | 24.98 | 11.20 | 8 | 115372 | 73 | 70812991 |
Ear pain | 24.89 | 11.20 | 7 | 115373 | 27592 | 70785472 |
Drug withdrawal syndrome | 24.88 | 11.20 | 11 | 115369 | 32704 | 70780360 |
Anaphylactic reaction | 24.81 | 11.20 | 53 | 115327 | 74921 | 70738143 |
Hepatitis cholestatic | 24.79 | 11.20 | 60 | 115320 | 12590 | 70800474 |
Thyroiditis acute | 24.78 | 11.20 | 10 | 115370 | 186 | 70812878 |
Eosinophilic pneumonia | 24.73 | 11.20 | 35 | 115345 | 4870 | 70808194 |
Blood thyroid stimulating hormone decreased | 24.71 | 11.20 | 37 | 115343 | 5417 | 70807647 |
Intra-abdominal haematoma | 24.69 | 11.20 | 26 | 115354 | 2666 | 70810398 |
Urinary tract infection | 24.69 | 11.20 | 272 | 115108 | 248497 | 70564567 |
Intentional overdose | 24.64 | 11.20 | 80 | 115300 | 98355 | 70714709 |
Depressed mood | 24.63 | 11.20 | 21 | 115359 | 43799 | 70769265 |
Erythema | 24.55 | 11.20 | 207 | 115173 | 199356 | 70613708 |
Drug ineffective | 24.29 | 11.20 | 1266 | 114114 | 938486 | 69874578 |
Medication error | 24.12 | 11.20 | 167 | 115213 | 56745 | 70756319 |
Ear infection | 24.09 | 11.20 | 8 | 115372 | 28328 | 70784736 |
Pulmonary embolism | 23.82 | 11.20 | 152 | 115228 | 155715 | 70657349 |
Nasal congestion | 23.82 | 11.20 | 44 | 115336 | 65628 | 70747436 |
Urine iodine increased | 23.66 | 11.20 | 5 | 115375 | 5 | 70813059 |
Iodine uptake abnormal | 23.66 | 11.20 | 5 | 115375 | 5 | 70813059 |
Haemorrhagic diathesis | 23.64 | 11.20 | 37 | 115343 | 5630 | 70807434 |
Left atrial enlargement | 23.54 | 11.20 | 17 | 115363 | 1049 | 70812015 |
Cystitis | 23.46 | 11.20 | 25 | 115355 | 46916 | 70766148 |
Blood creatine increased | 23.33 | 11.20 | 47 | 115333 | 8717 | 70804347 |
Platelet count decreased | 23.23 | 11.20 | 182 | 115198 | 178040 | 70635024 |
Tri-iodothyronine increased | 23.15 | 11.20 | 10 | 115370 | 222 | 70812842 |
Retroperitoneal haemorrhage | 23.12 | 11.20 | 35 | 115345 | 5174 | 70807890 |
Acute generalised exanthematous pustulosis | 23.00 | 11.20 | 66 | 115314 | 15331 | 70797733 |
Pemphigoid | 22.81 | 11.20 | 62 | 115318 | 13960 | 70799104 |
Aortic valve incompetence | 22.81 | 11.20 | 47 | 115333 | 8857 | 70804207 |
Device inappropriate shock delivery | 22.78 | 11.20 | 7 | 115373 | 55 | 70813009 |
Alveolar proteinosis | 22.66 | 11.20 | 14 | 115366 | 665 | 70812399 |
Vascular purpura | 22.52 | 11.20 | 25 | 115355 | 2721 | 70810343 |
Secondary hyperthyroidism | 22.35 | 11.20 | 6 | 115374 | 27 | 70813037 |
Cardiac pacemaker insertion | 22.31 | 11.20 | 35 | 115345 | 5337 | 70807727 |
Accidental exposure to product | 22.03 | 11.20 | 9 | 115371 | 28042 | 70785022 |
Diabetes mellitus | 21.96 | 11.20 | 53 | 115327 | 71771 | 70741293 |
Jaundice | 21.81 | 11.20 | 148 | 115232 | 49960 | 70763104 |
Halo vision | 21.66 | 11.20 | 13 | 115367 | 586 | 70812478 |
Conduction disorder | 21.57 | 11.20 | 26 | 115354 | 3092 | 70809972 |
Hepatic enzyme increased | 21.56 | 11.20 | 158 | 115222 | 156832 | 70656232 |
Neonatal pneumonia | 21.51 | 11.20 | 6 | 115374 | 32 | 70813032 |
Neonatal hypotension | 21.51 | 11.20 | 6 | 115374 | 32 | 70813032 |
Acne | 21.34 | 11.20 | 7 | 115373 | 24982 | 70788082 |
Supine hypertension | 21.31 | 11.20 | 11 | 115369 | 368 | 70812696 |
Cell death | 21.22 | 11.20 | 30 | 115350 | 4170 | 70808894 |
Supraventricular extrasystoles | 21.19 | 11.20 | 37 | 115343 | 6161 | 70806903 |
Localised infection | 21.06 | 11.20 | 14 | 115366 | 33144 | 70779920 |
Cyanosis | 20.95 | 11.20 | 84 | 115296 | 23122 | 70789942 |
Electrocardiogram QRS complex prolonged | 20.84 | 11.20 | 48 | 115332 | 9758 | 70803306 |
Mucosal inflammation | 20.80 | 11.20 | 50 | 115330 | 67800 | 70745264 |
Device capturing issue | 20.78 | 11.20 | 6 | 115374 | 37 | 70813027 |
Bundle branch block | 20.77 | 11.20 | 18 | 115362 | 1448 | 70811616 |
Cardiomegaly | 20.70 | 11.20 | 87 | 115293 | 24458 | 70788606 |
Product quality issue | 20.66 | 11.20 | 12 | 115368 | 30549 | 70782515 |
Irritability | 20.66 | 11.20 | 19 | 115361 | 38206 | 70774858 |
Pharyngitis | 20.66 | 11.20 | 4 | 115376 | 20347 | 70792717 |
Myocardial ischaemia | 20.58 | 11.20 | 86 | 115294 | 24114 | 70788950 |
Feeling cold | 20.41 | 11.20 | 8 | 115372 | 25562 | 70787502 |
Skin disorder | 20.41 | 11.20 | 12 | 115368 | 30345 | 70782719 |
Hepatotoxicity | 20.40 | 11.20 | 132 | 115248 | 43854 | 70769210 |
Subcutaneous haematoma | 20.33 | 11.20 | 23 | 115357 | 2556 | 70810508 |
Lupus pneumonitis | 20.29 | 11.20 | 7 | 115373 | 82 | 70812982 |
Aerophagia | 20.25 | 11.20 | 6 | 115374 | 41 | 70813023 |
Body temperature increased | 20.15 | 11.20 | 21 | 115359 | 39813 | 70773251 |
Coma uraemic | 20.13 | 11.20 | 6 | 115374 | 42 | 70813022 |
Musculoskeletal disorder | 20.11 | 11.20 | 4 | 115376 | 19967 | 70793097 |
Oliguria | 20.10 | 11.20 | 62 | 115318 | 14989 | 70798075 |
Conjunctival haemorrhage | 19.96 | 11.20 | 33 | 115347 | 5257 | 70807807 |
Hypophonesis | 19.73 | 11.20 | 5 | 115375 | 17 | 70813047 |
Paraesthesia | 19.73 | 11.20 | 147 | 115233 | 145390 | 70667674 |
Inappropriate schedule of product administration | 19.61 | 11.20 | 99 | 115281 | 107456 | 70705608 |
Joint stiffness | 19.60 | 11.20 | 17 | 115363 | 35159 | 70777905 |
Central nervous system injury | 19.52 | 11.20 | 8 | 115372 | 155 | 70812909 |
Orchitis | 19.24 | 11.20 | 16 | 115364 | 1216 | 70811848 |
Hypoxic-ischaemic encephalopathy | 19.22 | 11.20 | 39 | 115341 | 7269 | 70805795 |
Pseudolymphoma | 19.21 | 11.20 | 15 | 115365 | 1042 | 70812022 |
Sciatica | 19.18 | 11.20 | 8 | 115372 | 24619 | 70788445 |
Supraventricular tachycardia | 19.13 | 11.20 | 73 | 115307 | 19637 | 70793427 |
Thyroid function test abnormal | 19.13 | 11.20 | 24 | 115356 | 2973 | 70810091 |
Amaurosis | 19.05 | 11.20 | 15 | 115365 | 1055 | 70812009 |
Diaphragmatic paralysis | 18.96 | 11.20 | 15 | 115365 | 1062 | 70812002 |
Osteonecrosis | 18.95 | 11.20 | 12 | 115368 | 29148 | 70783916 |
Amnesia | 18.86 | 11.20 | 35 | 115345 | 52120 | 70760944 |
Atrioventricular block second degree | 18.82 | 11.20 | 37 | 115343 | 6741 | 70806323 |
Sudden death | 18.82 | 11.20 | 76 | 115304 | 20988 | 70792076 |
Aortic valve stenosis | 18.80 | 11.20 | 31 | 115349 | 4928 | 70808136 |
Bone disorder | 18.71 | 11.20 | 3 | 115377 | 17487 | 70795577 |
Viral infection | 18.57 | 11.20 | 21 | 115359 | 38370 | 70774694 |
Acute interstitial pneumonitis | 18.56 | 11.20 | 15 | 115365 | 1095 | 70811969 |
Arrhythmia supraventricular | 18.51 | 11.20 | 19 | 115361 | 1891 | 70811173 |
Normocytic anaemia | 18.45 | 11.20 | 26 | 115354 | 3604 | 70809460 |
Bundle branch block right | 18.36 | 11.20 | 48 | 115332 | 10562 | 70802502 |
Conjunctivitis | 18.21 | 11.20 | 7 | 115373 | 22629 | 70790435 |
Pulseless electrical activity | 18.17 | 11.20 | 55 | 115325 | 13160 | 70799904 |
Respiratory disorder neonatal | 18.16 | 11.20 | 6 | 115374 | 61 | 70813003 |
Blood pressure decreased | 18.09 | 11.20 | 228 | 115152 | 91287 | 70721777 |
Intentional self-injury | 17.99 | 11.20 | 15 | 115365 | 31635 | 70781429 |
Withdrawal syndrome | 17.98 | 11.20 | 9 | 115371 | 24895 | 70788169 |
Crepitations | 17.80 | 11.20 | 42 | 115338 | 8672 | 70804392 |
Thyroxine free decreased | 17.74 | 11.20 | 14 | 115366 | 988 | 70812076 |
Heart transplant | 17.72 | 11.20 | 16 | 115364 | 1359 | 70811705 |
Traumatic haemothorax | 17.70 | 11.20 | 10 | 115370 | 402 | 70812662 |
Unevaluable event | 17.68 | 11.20 | 145 | 115235 | 51918 | 70761146 |
Agranulocytosis | 17.52 | 11.20 | 119 | 115261 | 40179 | 70772885 |
Oral pain | 17.50 | 11.20 | 13 | 115367 | 29053 | 70784011 |
Listless | 17.34 | 11.20 | 25 | 115355 | 3538 | 70809526 |
Local anaesthetic systemic toxicity | 17.31 | 11.20 | 13 | 115367 | 852 | 70812212 |
Vascular pseudoaneurysm | 17.31 | 11.20 | 24 | 115356 | 3277 | 70809787 |
Injection site haemorrhage | 17.29 | 11.20 | 10 | 115370 | 25517 | 70787547 |
Plasma cell myeloma | 17.29 | 11.20 | 61 | 115319 | 73140 | 70739924 |
Hyperglycaemia | 17.29 | 11.20 | 51 | 115329 | 64621 | 70748443 |
Orthostatic hypertension | 17.19 | 11.20 | 12 | 115368 | 702 | 70812362 |
Thrombotic microangiopathy | 17.11 | 11.20 | 4 | 115376 | 17844 | 70795220 |
Wrong technique in product usage process | 17.07 | 11.20 | 56 | 115324 | 68642 | 70744422 |
Atrioventricular dissociation | 17.01 | 11.20 | 9 | 115371 | 317 | 70812747 |
Blood glucose increased | 17 | 11.20 | 98 | 115282 | 102884 | 70710180 |
Neuralgia | 16.96 | 11.20 | 13 | 115367 | 28590 | 70784474 |
Pain in jaw | 16.93 | 11.20 | 27 | 115353 | 42642 | 70770422 |
Device issue | 16.87 | 11.20 | 9 | 115371 | 24016 | 70789048 |
Tooth disorder | 16.76 | 11.20 | 9 | 115371 | 23929 | 70789135 |
Gastroenteritis viral | 16.66 | 11.20 | 7 | 115373 | 21448 | 70791616 |
Cardiorenal syndrome | 16.49 | 11.20 | 16 | 115364 | 1488 | 70811576 |
Electrocardiogram RR interval prolonged | 16.42 | 11.20 | 4 | 115376 | 11 | 70813053 |
Dysgeusia | 16.37 | 11.20 | 35 | 115345 | 49467 | 70763597 |
Crying | 16.33 | 11.20 | 7 | 115373 | 21192 | 70791872 |
Paranoia | 16.32 | 11.20 | 4 | 115376 | 17284 | 70795780 |
Non-compaction cardiomyopathy | 16.30 | 11.20 | 5 | 115375 | 39 | 70813025 |
Endovenous ablation | 16.27 | 11.20 | 3 | 115377 | 0 | 70813064 |
Concomitant disease aggravated | 16.27 | 11.20 | 50 | 115330 | 12064 | 70801000 |
Ocular hyperaemia | 16.20 | 11.20 | 10 | 115370 | 24629 | 70788435 |
Hepatic cyst | 16.19 | 11.20 | 31 | 115349 | 5540 | 70807524 |
Ulcer | 16.19 | 11.20 | 11 | 115369 | 25743 | 70787321 |
Burning sensation | 16.17 | 11.20 | 39 | 115341 | 52831 | 70760233 |
Anti-thyroid antibody positive | 16.17 | 11.20 | 10 | 115370 | 476 | 70812588 |
Blood pressure systolic increased | 16.16 | 11.20 | 44 | 115336 | 57215 | 70755849 |
Eye pain | 16.12 | 11.20 | 19 | 115361 | 34083 | 70778981 |
Chronic kidney disease | 16.11 | 11.20 | 161 | 115219 | 60896 | 70752168 |
Systemic inflammatory response syndrome | 16.08 | 11.20 | 46 | 115334 | 10666 | 70802398 |
Scrotal oedema | 16.04 | 11.20 | 15 | 115365 | 1333 | 70811731 |
Splenic injury | 16.00 | 11.20 | 8 | 115372 | 250 | 70812814 |
Accessory cardiac pathway | 15.93 | 11.20 | 4 | 115376 | 13 | 70813051 |
Full blood count abnormal | 15.88 | 11.20 | 19 | 115361 | 33859 | 70779205 |
Neuropathy peripheral | 15.88 | 11.20 | 131 | 115249 | 126765 | 70686299 |
Colitis | 15.87 | 11.20 | 52 | 115328 | 63762 | 70749302 |
Sneezing | 15.85 | 11.20 | 4 | 115376 | 16947 | 70796117 |
Transplant rejection | 15.68 | 11.20 | 5 | 115375 | 18166 | 70794898 |
Anticoagulation drug level below therapeutic | 15.67 | 11.20 | 15 | 115365 | 1372 | 70811692 |
Pericarditis fungal | 15.63 | 11.20 | 7 | 115373 | 170 | 70812894 |
Foot deformity | 15.62 | 11.20 | 7 | 115373 | 20648 | 70792416 |
Chorea | 15.49 | 11.20 | 18 | 115362 | 2060 | 70811004 |
Procedural pain | 15.46 | 11.20 | 5 | 115375 | 18004 | 70795060 |
Coagulation test abnormal | 15.44 | 11.20 | 14 | 115366 | 1196 | 70811868 |
Toxic nodular goitre | 15.39 | 11.20 | 5 | 115375 | 48 | 70813016 |
Bone erosion | 15.36 | 11.20 | 3 | 115377 | 15170 | 70797894 |
Thyrotoxic periodic paralysis | 15.36 | 11.20 | 6 | 115374 | 102 | 70812962 |
Subdural haemorrhage | 15.32 | 11.20 | 30 | 115350 | 5451 | 70807613 |
Throat tightness | 15.32 | 11.20 | 11 | 115369 | 25011 | 70788053 |
Obstructive airways disorder | 15.31 | 11.20 | 12 | 115368 | 26101 | 70786963 |
Mental disorder | 15.31 | 11.20 | 14 | 115366 | 28226 | 70784838 |
Paroxysmal arrhythmia | 15.30 | 11.20 | 5 | 115375 | 49 | 70813015 |
Haemorrhagic thyroid cyst | 15.28 | 11.20 | 4 | 115376 | 16 | 70813048 |
Reduced facial expression | 15.28 | 11.20 | 19 | 115361 | 2333 | 70810731 |
Sopor | 15.22 | 11.20 | 95 | 115285 | 31172 | 70781892 |
Rash pruritic | 15.21 | 11.20 | 52 | 115328 | 62939 | 70750125 |
Intervertebral disc protrusion | 15.18 | 11.20 | 8 | 115372 | 21495 | 70791569 |
Lung opacity | 15.15 | 11.20 | 24 | 115356 | 3689 | 70809375 |
Electrocardiogram T wave abnormal | 15.10 | 11.20 | 23 | 115357 | 3419 | 70809645 |
Dry skin | 15.03 | 11.20 | 44 | 115336 | 55887 | 70757177 |
Anxiety | 14.99 | 11.20 | 260 | 115120 | 220070 | 70592994 |
Diffuse vasculitis | 14.95 | 11.20 | 6 | 115374 | 110 | 70812954 |
Neutrophil count increased | 14.86 | 11.20 | 13 | 115367 | 26782 | 70786282 |
Ventricular remodelling | 14.85 | 11.20 | 6 | 115374 | 112 | 70812952 |
Faecaloma | 14.85 | 11.20 | 44 | 115336 | 10407 | 70802657 |
Congestive hepatopathy | 14.82 | 11.20 | 25 | 115355 | 4049 | 70809015 |
Retroperitoneal haematoma | 14.81 | 11.20 | 28 | 115352 | 4957 | 70808107 |
Hypovolaemic shock | 14.80 | 11.20 | 45 | 115335 | 10792 | 70802272 |
Mesenteric artery thrombosis | 14.73 | 11.20 | 10 | 115370 | 559 | 70812505 |
Fascial rupture | 14.73 | 11.20 | 4 | 115376 | 19 | 70813045 |
Intraventricular haemorrhage | 14.69 | 11.20 | 26 | 115354 | 4375 | 70808689 |
Limb discomfort | 14.64 | 11.20 | 16 | 115364 | 29689 | 70783375 |
Thyroglobulin increased | 14.62 | 11.20 | 5 | 115375 | 57 | 70813007 |
Serotonin syndrome | 14.58 | 11.20 | 29 | 115351 | 42085 | 70770979 |
Inflammation | 14.57 | 11.20 | 72 | 115308 | 78593 | 70734471 |
Alveolitis necrotising | 14.56 | 11.20 | 4 | 115376 | 20 | 70813044 |
Treatment noncompliance | 14.53 | 11.20 | 34 | 115346 | 46540 | 70766524 |
Diabetic ketoacidosis | 14.43 | 11.20 | 18 | 115362 | 31494 | 70781570 |
Renal function test abnormal | 14.38 | 11.20 | 25 | 115355 | 4149 | 70808915 |
Photosensitivity reaction | 14.37 | 11.20 | 66 | 115314 | 19274 | 70793790 |
Hypothermia | 14.36 | 11.20 | 69 | 115311 | 20525 | 70792539 |
Bone marrow failure | 14.33 | 11.20 | 37 | 115343 | 48973 | 70764091 |
Therapeutic drug monitoring analysis not performed | 14.32 | 11.20 | 15 | 115365 | 1529 | 70811535 |
Failure to suspend medication | 14.28 | 11.20 | 9 | 115371 | 443 | 70812621 |
Thrombin time prolonged | 14.22 | 11.20 | 8 | 115372 | 319 | 70812745 |
Dry eye | 14.20 | 11.20 | 19 | 115361 | 32263 | 70780801 |
Brain natriuretic peptide increased | 14.17 | 11.20 | 37 | 115343 | 8134 | 70804930 |
Generalised tonic-clonic seizure | 14.16 | 11.20 | 29 | 115351 | 41632 | 70771432 |
Liver function test abnormal | 14.14 | 11.20 | 157 | 115223 | 60989 | 70752075 |
Hepatojugular reflux | 14.07 | 11.20 | 10 | 115370 | 602 | 70812462 |
Dissociation | 14.02 | 11.20 | 22 | 115358 | 3354 | 70809710 |
Hypoglycaemic seizure | 14.00 | 11.20 | 11 | 115369 | 771 | 70812293 |
Red blood cell sedimentation rate abnormal | 13.90 | 11.20 | 7 | 115373 | 19296 | 70793768 |
C-reactive protein increased | 13.87 | 11.20 | 114 | 115266 | 110403 | 70702661 |
Oesophageal infection | 13.82 | 11.20 | 10 | 115370 | 619 | 70812445 |
Gastroenteritis aeromonas | 13.81 | 11.20 | 4 | 115376 | 25 | 70813039 |
Oedema genital | 13.78 | 11.20 | 9 | 115371 | 471 | 70812593 |
Ventricular dysfunction | 13.68 | 11.20 | 29 | 115351 | 5575 | 70807489 |
Eye swelling | 13.66 | 11.20 | 11 | 115369 | 23603 | 70789461 |
Device dislocation | 13.64 | 11.20 | 10 | 115370 | 22497 | 70790567 |
Splenic haemorrhage | 13.54 | 11.20 | 10 | 115370 | 639 | 70812425 |
Diverticulum intestinal | 13.53 | 11.20 | 36 | 115344 | 8005 | 70805059 |
Sleep disorder | 13.50 | 11.20 | 63 | 115317 | 69809 | 70743255 |
Sinus disorder | 13.46 | 11.20 | 7 | 115373 | 18952 | 70794112 |
Adrenal haematoma | 13.46 | 11.20 | 6 | 115374 | 144 | 70812920 |
Injection site warmth | 13.45 | 11.20 | 3 | 115377 | 13822 | 70799242 |
Drug reaction with eosinophilia and systemic symptoms | 13.43 | 11.20 | 149 | 115231 | 57864 | 70755200 |
Foreign body | 13.40 | 11.20 | 19 | 115361 | 2649 | 70810415 |
Tooth infection | 13.39 | 11.20 | 5 | 115375 | 16458 | 70796606 |
Lymphadenopathy | 13.39 | 11.20 | 38 | 115342 | 48753 | 70764311 |
Live birth | 13.38 | 11.20 | 3 | 115377 | 13776 | 70799288 |
Leukopenia | 13.33 | 11.20 | 110 | 115270 | 106450 | 70706614 |
Vascular stent thrombosis | 13.33 | 11.20 | 22 | 115358 | 3501 | 70809563 |
Nodule | 13.28 | 11.20 | 8 | 115372 | 19961 | 70793103 |
Swollen tongue | 13.27 | 11.20 | 25 | 115355 | 37021 | 70776043 |
Electrocardiogram QRS complex shortened | 13.22 | 11.20 | 10 | 115370 | 663 | 70812401 |
Hypochromasia | 13.20 | 11.20 | 10 | 115370 | 664 | 70812400 |
Graft versus host disease | 13.20 | 11.20 | 4 | 115376 | 15019 | 70798045 |
Rash maculo-papular | 13.20 | 11.20 | 133 | 115247 | 50412 | 70762652 |
Arteriosclerotic retinopathy | 13.18 | 11.20 | 4 | 115376 | 30 | 70813034 |
Infective pericardial effusion | 13.18 | 11.20 | 4 | 115376 | 30 | 70813034 |
Vascular graft | 13.10 | 11.20 | 16 | 115364 | 1928 | 70811136 |
Axonal neuropathy | 13.10 | 11.20 | 16 | 115364 | 1928 | 70811136 |
Altered visual depth perception | 13.08 | 11.20 | 8 | 115372 | 373 | 70812691 |
Chest X-ray abnormal | 13.06 | 11.20 | 33 | 115347 | 7111 | 70805953 |
Ventricular enlargement | 13.03 | 11.20 | 9 | 115371 | 517 | 70812547 |
Drug clearance decreased | 13.03 | 11.20 | 20 | 115360 | 2993 | 70810071 |
Hypernatraemia | 13.00 | 11.20 | 48 | 115332 | 12713 | 70800351 |
Bronchitis | 12.93 | 11.20 | 125 | 115255 | 117118 | 70695946 |
Hypocoagulable state | 12.91 | 11.20 | 16 | 115364 | 1957 | 70811107 |
Blood triglycerides increased | 12.90 | 11.20 | 8 | 115372 | 19656 | 70793408 |
Sinus arrhythmia | 12.88 | 11.20 | 16 | 115364 | 1962 | 70811102 |
Colonic haematoma | 12.86 | 11.20 | 5 | 115375 | 84 | 70812980 |
Electrocardiogram low voltage | 12.85 | 11.20 | 4 | 115376 | 33 | 70813031 |
Neuroleptic malignant syndrome | 12.83 | 11.20 | 14 | 115366 | 25993 | 70787071 |
Foot fracture | 12.83 | 11.20 | 8 | 115372 | 19592 | 70793472 |
Amyloidosis | 12.80 | 11.20 | 19 | 115361 | 2760 | 70810304 |
Toothache | 12.80 | 11.20 | 7 | 115373 | 18423 | 70794641 |
Lymphoid tissue hyperplasia | 12.80 | 11.20 | 7 | 115373 | 264 | 70812800 |
Weight decreased | 12.78 | 11.20 | 396 | 114984 | 310092 | 70502972 |
Pulmonary haemorrhage | 12.75 | 11.20 | 50 | 115330 | 13623 | 70799441 |
Aphthous ulcer | 12.70 | 11.20 | 4 | 115376 | 14652 | 70798412 |
Kidney infection | 12.65 | 11.20 | 8 | 115372 | 19447 | 70793617 |
Fasting | 12.64 | 11.20 | 4 | 115376 | 35 | 70813029 |
Prerenal failure | 12.61 | 11.20 | 21 | 115359 | 3365 | 70809699 |
Oesophageal achalasia | 12.61 | 11.20 | 10 | 115370 | 711 | 70812353 |
Obesity | 12.57 | 11.20 | 15 | 115365 | 26756 | 70786308 |
Carpal tunnel syndrome | 12.56 | 11.20 | 6 | 115374 | 17051 | 70796013 |
Product storage error | 12.55 | 11.20 | 4 | 115376 | 14537 | 70798527 |
Oesophageal adenocarcinoma recurrent | 12.54 | 11.20 | 4 | 115376 | 36 | 70813028 |
Hyperthermia | 12.46 | 11.20 | 57 | 115323 | 16614 | 70796450 |
Iron deficiency anaemia | 12.44 | 11.20 | 72 | 115308 | 23000 | 70790064 |
Hospitalisation | 12.36 | 11.20 | 81 | 115299 | 82487 | 70730577 |
Optic atrophy | 12.33 | 11.20 | 15 | 115365 | 1800 | 70811264 |
Hepatitis | 12.33 | 11.20 | 130 | 115250 | 49850 | 70763214 |
Toxic epidermal necrolysis | 12.28 | 11.20 | 108 | 115272 | 39449 | 70773615 |
Haemoperitoneum | 12.26 | 11.20 | 23 | 115357 | 4048 | 70809016 |
Wolff-Parkinson-White syndrome | 12.24 | 11.20 | 7 | 115373 | 288 | 70812776 |
Electrocardiogram T wave inversion | 12.24 | 11.20 | 26 | 115354 | 5005 | 70808059 |
Dry mouth | 12.20 | 11.20 | 66 | 115314 | 70391 | 70742673 |
Secretion discharge | 12.20 | 11.20 | 3 | 115377 | 12930 | 70800134 |
Lip swelling | 12.18 | 11.20 | 23 | 115357 | 34031 | 70779033 |
Demyelinating polyneuropathy | 12.18 | 11.20 | 14 | 115366 | 1583 | 70811481 |
Tachypnoea | 12.11 | 11.20 | 84 | 115296 | 28554 | 70784510 |
Ventricular flutter | 12.10 | 11.20 | 5 | 115375 | 99 | 70812965 |
Ventricular hypokinesia | 12.07 | 11.20 | 35 | 115345 | 8177 | 70804887 |
Linear IgA disease | 12.07 | 11.20 | 19 | 115361 | 2905 | 70810159 |
Sinus arrest | 12.06 | 11.20 | 20 | 115360 | 3195 | 70809869 |
Paraesthesia oral | 12.02 | 11.20 | 5 | 115375 | 15412 | 70797652 |
Pelvic fracture | 12.01 | 11.20 | 43 | 115337 | 11218 | 70801846 |
Panic attack | 11.95 | 11.20 | 11 | 115369 | 22108 | 70790956 |
Cardiac dysfunction | 11.94 | 11.20 | 21 | 115359 | 3516 | 70809548 |
Microcytic anaemia | 11.94 | 11.20 | 25 | 115355 | 4764 | 70808300 |
Transaminases increased | 11.93 | 11.20 | 123 | 115257 | 46895 | 70766169 |
Postrenal failure | 11.92 | 11.20 | 9 | 115371 | 595 | 70812469 |
Cyst | 11.90 | 11.20 | 3 | 115377 | 12716 | 70800348 |
Lung consolidation | 11.83 | 11.20 | 35 | 115345 | 8271 | 70804793 |
Blood cyanide increased | 11.82 | 11.20 | 4 | 115376 | 44 | 70813020 |
Flatulence | 11.81 | 11.20 | 28 | 115352 | 38153 | 70774911 |
Petechiae | 11.79 | 11.20 | 62 | 115318 | 19110 | 70793954 |
Extradural haematoma | 11.76 | 11.20 | 18 | 115362 | 2687 | 70810377 |
Wound dehiscence | 11.69 | 11.20 | 29 | 115351 | 6179 | 70806885 |
Eosinophilia myalgia syndrome | 11.67 | 11.20 | 3 | 115377 | 11 | 70813053 |
Purpura | 11.66 | 11.20 | 59 | 115321 | 17916 | 70795148 |
Impaired work ability | 11.65 | 11.20 | 6 | 115374 | 16334 | 70796730 |
Nephroangiosclerosis | 11.63 | 11.20 | 7 | 115373 | 317 | 70812747 |
Dilatation ventricular | 11.58 | 11.20 | 22 | 115358 | 3909 | 70809155 |
Optic disc haemorrhage | 11.49 | 11.20 | 5 | 115375 | 113 | 70812951 |
Liver scan abnormal | 11.44 | 11.20 | 4 | 115376 | 49 | 70813015 |
Laryngitis | 11.33 | 11.20 | 4 | 115376 | 13627 | 70799437 |
Subdural haematoma evacuation | 11.29 | 11.20 | 4 | 115376 | 51 | 70813013 |
Arterial insufficiency | 11.25 | 11.20 | 7 | 115373 | 337 | 70812727 |
Therapy non-responder | 11.24 | 11.20 | 76 | 115304 | 76839 | 70736225 |
Dialysis | 11.21 | 11.20 | 57 | 115323 | 17345 | 70795719 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Cardiac arrest neonatal | 41.28 | 40.06 | 11 | 86 | 83 | 89612 |
Source | Code | Description |
---|---|---|
ATC | C01BD01 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY ANTIARRHYTHMICS, CLASS I AND III Antiarrhythmics, class III |
FDA EPC | N0000175426 | Antiarrhythmic |
CHEBI has role | CHEBI:35554 | cardiovascular agent |
MeSH PA | D000889 | Anti-Arrhythmia Agents |
MeSH PA | D002317 | Cardiovascular Agents |
MeSH PA | D065609 | Cytochrome P-450 CYP1A2 Inhibitors |
MeSH PA | D065688 | Cytochrome P-450 CYP2C9 Inhibitors |
MeSH PA | D065690 | Cytochrome P-450 CYP2D6 Inhibitors |
MeSH PA | D065692 | Cytochrome P-450 CYP3A Inhibitors |
MeSH PA | D065607 | Cytochrome P-450 Enzyme Inhibitors |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D049990 | Membrane Transport Modulators |
MeSH PA | D065606 | Metabolic Side Effects of Drugs and Substances |
MeSH PA | D026902 | Potassium Channel Blockers |
MeSH PA | D026941 | Sodium Channel Blockers |
MeSH PA | D014665 | Vasodilator Agents |
FDA MoA | N0000182137 | Cytochrome P450 2D6 Inhibitors |
FDA MoA | N0000182138 | Cytochrome P450 1A2 Inhibitors |
FDA MoA | N0000182141 | Cytochrome P450 3A4 Inhibitors |
FDA MoA | N0000185503 | P-Glycoprotein Inhibitors |
FDA MoA | N0000185504 | Cytochrome P450 2C9 Inhibitors |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Ventricular fibrillation | indication | 71908006 | |
Prevention of Ventricular Fibrillation | indication | ||
Life-Threatening Ventricular Tachycardia | indication | ||
Atrial fibrillation | off-label use | 49436004 | DOID:0060224 |
Cardioversion of Atrial Fibrillation | off-label use | ||
Prevention of Post Cardio-Thoracic Surgery Atrial Fibrillation | off-label use | ||
Complete atrioventricular block | contraindication | 27885002 | |
Torsades de pointes | contraindication | 31722008 | |
Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
Extrinsic allergic alveolitis | contraindication | 37471005 | DOID:841 |
Hypothyroidism | contraindication | 40930008 | DOID:1459 |
Hypokalemia | contraindication | 43339004 | |
Chronic heart failure | contraindication | 48447003 | |
Bradycardia | contraindication | 48867003 | |
Refractive keratoplasty by laser surgery | contraindication | 58076004 | |
Sinus node dysfunction | contraindication | 60423000 | |
Interstitial pneumonia | contraindication | 64667001 | |
Optic neuritis | contraindication | 66760008 | DOID:1210 |
Corneal deposit | contraindication | 74460005 | DOID:11547 |
Disorder of optic nerve | contraindication | 77157004 | DOID:1891 |
Pulmonary hemorrhage | contraindication | 78144005 | |
Cardiogenic shock | contraindication | 89138009 | |
Thyrotoxicosis | contraindication | 90739004 | DOID:7997 |
Prolonged QT interval | contraindication | 111975006 | |
Liver function tests abnormal | contraindication | 166603001 | |
Hypomagnesemia | contraindication | 190855004 | |
Second degree atrioventricular block | contraindication | 195042002 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Drug-induced hepatitis | contraindication | 235876009 | |
Pregnancy, function | contraindication | 289908002 | |
Peripheral nerve disease | contraindication | 302226006 | |
Eosinophilic asthma | contraindication | 367542003 | DOID:9498 |
Surgical procedure | contraindication | 387713003 | |
Breastfeeding (mother) | contraindication | 413712001 | |
Chronic lung disease | contraindication | 413839001 | |
Congenital long QT syndrome | contraindication | 442917000 | |
Syncope due to Bradycardia | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 8.72 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 | Ion channel | BLOCKER | IC50 | 5 | WOMBAT-PK | CHEMBL | |||
Cytochrome P450 3A4 | Enzyme | Ki | 6.22 | WOMBAT-PK | |||||
Beta-1 adrenergic receptor | GPCR | IC50 | 4.70 | WOMBAT-PK | |||||
Sodium channel protein type 5 subunit alpha | Ion channel | BLOCKER | IC50 | 7.10 | WOMBAT-PK | ||||
Mu-type opioid receptor | GPCR | Ki | 5.11 | DRUG MATRIX | |||||
D(1A) dopamine receptor | GPCR | Ki | 5.34 | DRUG MATRIX | |||||
D(2) dopamine receptor | GPCR | Ki | 5.18 | DRUG MATRIX | |||||
Alpha-2A adrenergic receptor | GPCR | IC50 | 6.30 | WOMBAT-PK | |||||
Sigma non-opioid intracellular receptor 1 | Membrane receptor | Ki | 7 | WOMBAT-PK | |||||
Thyroid hormone receptor alpha | Nuclear hormone receptor | IC50 | 5.64 | WOMBAT-PK | |||||
Thyroid hormone receptor beta | Nuclear hormone receptor | IC50 | 6.22 | WOMBAT-PK | |||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Enzyme | Ki | 7.60 | WOMBAT-PK | |||||
Multidrug resistance protein 1 | Transporter | Ki | 5.30 | WOMBAT-PK | |||||
Sodium-dependent serotonin transporter | Transporter | Ki | 5.91 | DRUG MATRIX | |||||
Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.65 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2A | GPCR | Ki | 5.99 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2B | GPCR | Ki | 6.23 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2C | GPCR | Ki | 6.67 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 6 | GPCR | Ki | 5.05 | DRUG MATRIX | |||||
Alpha-2B adrenergic receptor | GPCR | Ki | 5.23 | DRUG MATRIX | |||||
D(3) dopamine receptor | GPCR | Ki | 6.39 | DRUG MATRIX | |||||
Histamine H2 receptor | GPCR | Ki | 4.98 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M1 | GPCR | Ki | 6.20 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M2 | GPCR | Ki | 5.74 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M3 | GPCR | Ki | 6.17 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M4 | GPCR | Ki | 6.30 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M5 | GPCR | Ki | 5.97 | DRUG MATRIX | |||||
Beta-3 adrenergic receptor | GPCR | Ki | 4.50 | DRUG MATRIX | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 5.70 | DRUG MATRIX | |||||
Adenosine receptor A3 | GPCR | Ki | 5.00 | DRUG MATRIX | |||||
D(4) dopamine receptor | GPCR | Ki | 5.21 | DRUG MATRIX | |||||
Kappa-type opioid receptor | GPCR | Ki | 5.18 | DRUG MATRIX | |||||
Delta-type opioid receptor | GPCR | Ki | 5.55 | DRUG MATRIX | |||||
Cytochrome P450 2C9 | Enzyme | EC50 | 7.40 | WOMBAT-PK | |||||
Voltage-dependent T-type calcium channel subunit alpha-1H | Ion channel | Ki | 5.28 | WOMBAT-PK | |||||
Endothelin-1 receptor | GPCR | Ki | 4.79 | DRUG MATRIX | |||||
Squalene monooxygenase | Enzyme | IC50 | 4.92 | CHEMBL | |||||
Tyrosine-protein kinase Fyn | Kinase | IC50 | 6.09 | DRUG MATRIX | |||||
Receptor tyrosine-protein kinase erbB-2 | Kinase | IC50 | 5.04 | DRUG MATRIX | |||||
Squalene synthase | Enzyme | IC50 | 5.10 | CHEMBL | |||||
C-C chemokine receptor type 2 | GPCR | Ki | 5.37 | DRUG MATRIX | |||||
Substance-K receptor | GPCR | Ki | 5.19 | DRUG MATRIX | |||||
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Ion channel | IC50 | 5.35 | WOMBAT-PK | |||||
Potassium voltage-gated channel subfamily A member 7 | Ion channel | IC50 | 6 | WOMBAT-PK | |||||
B2 bradykinin receptor | GPCR | Ki | 5.12 | DRUG MATRIX | |||||
Melanocortin receptor 4 | GPCR | Ki | 4.88 | DRUG MATRIX | |||||
Melanocortin receptor 5 | GPCR | Ki | 5.05 | DRUG MATRIX | |||||
Melanocortin receptor 3 | GPCR | Ki | 4.97 | DRUG MATRIX | |||||
C-C chemokine receptor type 4 | GPCR | Ki | 4.94 | DRUG MATRIX | |||||
THAP domain-containing protein 1 | Unclassified | IC50 | 6.19 | WOMBAT-PK | |||||
NAD-dependent deacetylase sirtuin 3 | Enzyme | EC50 | 5.49 | CHEMBL | |||||
Lysine-specific demethylase PHF2 | Enzyme | IC50 | 4.08 | CHEMBL | |||||
Lysine-specific demethylase 5A | Enzyme | IC50 | 4 | CHEMBL | |||||
Lysine-specific demethylase 7A | Enzyme | IC50 | 4.10 | CHEMBL | |||||
Androgen receptor | Transcription factor | Ki | 4.55 | DRUG MATRIX | |||||
Lethal factor | Enzyme | IC50 | 5.46 | CHEMBL | |||||
5-hydroxytryptamine receptor 1B | GPCR | Ki | 4.41 | DRUG MATRIX | |||||
Membrane-associated progesterone receptor component 1 | Membrane receptor | IC50 | 6.93 | DRUG MATRIX | |||||
C-8 sterol isomerase | Enzyme | Ki | 7.21 | CHEMBL | |||||
Cruzipain | Enzyme | IC50 | 5.40 | CHEMBL | |||||
Sodium channel protein type 5 subunit alpha | Ion channel | BLOCKER | IC50 | 5.70 | IUPHAR |
ID | Source |
---|---|
4019606 | VUID |
N0000147701 | NUI |
D00636 | KEGG_DRUG |
19774-82-4 | SECONDARY_CAS_RN |
203114 | RXNORM |
C0002598 | UMLSCUI |
CHEBI:2663 | CHEBI |
BBI | PDB_CHEM_ID |
CHEMBL633 | ChEMBL_ID |
CHEMBL1083993 | ChEMBL_ID |
D000638 | MESH_DESCRIPTOR_UI |
DB01118 | DRUGBANK_ID |
2566 | IUPHAR_LIGAND_ID |
2012 | INN_ID |
N3RQ532IUT | UNII |
2157 | PUBCHEM_CID |
000629 | NDDF |
004484 | NDDF |
372821002 | SNOMEDCT_US |
52574003 | SNOMEDCT_US |
69236009 | SNOMEDCT_US |
4018065 | VANDF |
4019606 | VANDF |
13960 | MMSL |
4177 | MMSL |
d00002 | MMSL |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9875 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 26 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9875 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 26 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0185-0144 | TABLET | 200 mg | ORAL | ANDA | 27 sections |
Pacerone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0245-0144 | TABLET | 100 mg | ORAL | ANDA | 30 sections |
Pacerone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0245-0145 | TABLET | 400 mg | ORAL | ANDA | 27 sections |
Pacerone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0245-0145 | TABLET | 400 mg | ORAL | ANDA | 27 sections |
Pacerone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0245-0147 | TABLET | 200 mg | ORAL | ANDA | 30 sections |
Pacerone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0245-1645 | TABLET | 400 mg | ORAL | ANDA | 30 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-9815 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 16 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-9815 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 16 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-9815 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 16 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8258 | TABLET | 200 mg | ORAL | ANDA | 27 sections |
Amiodarone hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6556 | TABLET | 200 mg | ORAL | ANDA | 19 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6993 | TABLET | 200 mg | ORAL | ANDA | 28 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-843 | TABLET | 100 mg | ORAL | ANDA | 28 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-844 | TABLET | 200 mg | ORAL | ANDA | 28 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16714-845 | TABLET | 400 mg | ORAL | ANDA | 28 sections |
Amiodarone hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-796 | TABLET | 200 mg | ORAL | ANDA | 25 sections |
amiodarone hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-302 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 28 sections |
amiodarone hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-302 | INJECTION, SOLUTION | 50 mg | INTRAVENOUS | ANDA | 28 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29300-359 | TABLET | 200 mg | ORAL | ANDA | 19 sections |
Amiodarone HCl | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42494-307 | TABLET | 100 mg | ORAL | ANDA | 29 sections |
Amiodarone HCl | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42494-308 | TABLET | 200 mg | ORAL | ANDA | 29 sections |
Amiodarone HCl | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42494-309 | TABLET | 400 mg | ORAL | ANDA | 29 sections |
Nexterone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43066-150 | INJECTION, SOLUTION | 1.50 mg | INTRAVENOUS | NDA | 25 sections |
Nexterone | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43066-360 | INJECTION, SOLUTION | 1.80 mg | INTRAVENOUS | NDA | 25 sections |
Amiodarone Hydrochloride | Human Prescription Drug Label | 1 | 50090-3015 | TABLET | 200 mg | ORAL | ANDA | 30 sections |
Amiodarone Hydrochloride | Human Prescription Drug Label | 1 | 50090-3015 | TABLET | 200 mg | ORAL | ANDA | 30 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-3496 | TABLET | 200 mg | ORAL | ANDA | 27 sections |
Amiodarone Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-5062 | TABLET | 200 mg | ORAL | ANDA | 27 sections |