dimyristoylphosphatidylcholine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4651 18656-38-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dimyristoylphosphatidylcholine
  • dimyristoyl glycerophosphocholine
  • dimyristoyllecithin
  • ditetradecanoylglycerophosphorylcholine
  • ditetradecanoylphosphatidylcholine
  • DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-
  • dimyristoyl lecithin
A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes.
  • Molecular weight: 677.95
  • Formula: C36H72NO8P
  • CLOGP: 1.89
  • LIPINSKI: 1
  • HAC: 9
  • HDO: 0
  • TPSA: 111.19
  • ALOGS: -7.26
  • ROTB: 36

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
May 31, 2002 FDA IMCOR PHARMS CO

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Chills 42.95 41.36 19 359 96013 46589671

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Bronchopulmonary aspergillosis 41.16 40.85 13 493 12271 29939701

Pharmacologic Action:

SourceCodeDescription
MeSH PA D007202 Indicators and Reagents
CHEBI has role CHEBI:59132 antigens
CHEBI has role CHEBI:75771 mus musculus metabolite

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.51 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000168630 NUI
C0012456 UMLSCUI
CHEBI:45240 CHEBI
CHEMBL1201501 ChEMBL_ID
CHEMBL451503 ChEMBL_ID
DB11283 DRUGBANK_ID
D004134 MESH_DESCRIPTOR_UI
5459377 PUBCHEM_CID
U86ZGC74V5 UNII
1362902 RXNORM

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ABELCET HUMAN PRESCRIPTION DRUG LABEL 3 57665-101 INJECTION 3.40 mg INTRAVENOUS NDA 20 sections