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glycolic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4645 | 79-14-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPKAPK2,MTOR,NTRK2,PDK1,PDK2,PDK4,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70 | 53 | |||
| kinase-selectivity-class | ACVR2B,ACVRL1,AXL,BMX,BRAF,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,GRK2,MAP2K6,MAP3K14,MAPK7,MAPK8,PIK3CB,PIK3CD,PIK3CG,PRKDC,STK33,SYK,TEK,TGFBR1 | 23 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D003879 | Dermatologic Agents |
| MeSH PA | D007641 | Keratolytic Agents |
| CHEBI has role | CHEBI:25212 | metabolite |
| CHEBI has role | CHEBI:50176 | keratolytic drug |
| CHEBI has role | CHEBI:64952 | anti-HSV agent |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.75 | acidic |
| pKa2 | 13.56 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4024427 | VUID |
| N0000158138 | NUI |
| 4010220 | VANDF |
| 4024427 | VANDF |
| CHEBI:17497 | CHEBI |
| GOA | PDB_CHEM_ID |
| CHEMBL252557 | ChEMBL_ID |
| C031149 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB03085 | DRUGBANK_ID |
| 0WT12SX38S | UNII |
| 587318 | RXNORM |
| NOCODE | MMSL |
| 003591 | NDDF |
| C5848855 | UMLSCUI |
| 757 | PUBCHEM_CID |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Clear Cell Salicylic Clarifying Tonic | HUMAN OTC DRUG LABEL | 2 | 62742-4043 | LIQUID | 50 mg | TOPICAL | OTC monograph final | 4 sections |
| purifying s.o.s spotgel | HUMAN OTC DRUG LABEL | 2 | 71217-0044 | GEL | 2 g | TOPICAL | unapproved drug other | 7 sections |
| Glycolic Acid | HUMAN OTC DRUG LABEL | 1 | 71718-703 | LIQUID | 0.70 1 | TOPICAL | unapproved drug other | 9 sections |
| VILLAGE 11 FACTORY RELAX DAY AHA EXFOLIATING BODY | HUMAN OTC DRUG LABEL | 1 | 72470-050 | LOTION | 25.20 g | TOPICAL | unapproved drug other | 9 sections |
| Triple X-Lotion | HUMAN OTC DRUG LABEL | 3 | 80724-201 | LOTION | 3 g | TOPICAL | unapproved drug other | 9 sections |
| Glycolic Acid | HUMAN OTC DRUG LABEL | 1 | 81376-701 | LIQUID | 9 g | TOPICAL | unapproved drug other | 9 sections |
| Anubis Barcelona New Even | HUMAN OTC DRUG LABEL | 16 | 83021-033 | LOTION | 1.22 g | TOPICAL | OTC monograph final | 9 sections |
| AnubisMed | HUMAN OTC DRUG LABEL | 14 | 83021-401 | LIQUID | 17 g | TOPICAL | OTC monograph final | 9 sections |
| Cleansing Care Pads | HUMAN OTC DRUG LABEL | 2 | 84025-283 | LIQUID | 6 mg | CUTANEOUS | OTC Monograph Drug | 5 sections |
| Clarifying Serum | HUMAN OTC DRUG LABEL | 3 | 84423-062 | OIL | 0.16 g | CUTANEOUS | OTC Monograph Drug | 8 sections |
| BARUBT Intensive Peeling Solution | HUMAN OTC DRUG LABEL | 3 | 84712-011 | LOTION | 0.18 g | TOPICAL | OTC Monograph Drug | 12 sections |
| BARUBT Strawberry Pore Clay Stick | HUMAN OTC DRUG LABEL | 5 | 84712-018 | PASTE | 0.02 g | TOPICAL | OTC Monograph Drug | 12 sections |
| BARUBT Ocean Pore Clay Stick | HUMAN OTC DRUG LABEL | 4 | 84712-019 | PASTE | 0.02 g | CUTANEOUS | OTC Monograph Drug | 12 sections |
| Glycolic Acid 7% Toning Solution | HUMAN OTC DRUG LABEL | 1 | 84732-001 | LIQUID | 7 mg | CUTANEOUS | OTC Monograph Drug | 10 sections |
| Retinol plus AHA Cream | HUMAN OTC DRUG LABEL | 15 | 84785-0008 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| Skin White Pro Strength Kojic and Hyaluronic Skin Lightening Serum | HUMAN OTC DRUG LABEL | 7 | 84785-0010 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| GLYCOLIC Acid 50 BUFFERED Skin Chemical Peel | HUMAN OTC DRUG LABEL | 2 | 84785-0016 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| GLYCOLIC Acid 70 BUFFERED Skin Chemical Peel | HUMAN OTC DRUG LABEL | 2 | 84785-0017 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| GLYCOLIC 35 / LACTIC 45 Combo Peel | HUMAN OTC DRUG LABEL | 2 | 84785-0018 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| GLYCOLIC Acid 35 BUFFERED Skin Chemical Peel | HUMAN OTC DRUG LABEL | 2 | 84785-0019 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| GLYCOLIC Acid 35 Skin Chemical Peel | HUMAN OTC DRUG LABEL | 1 | 84785-0024 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| GLYCOLIC Acid 50 Skin Chemical Peel | HUMAN OTC DRUG LABEL | 1 | 84785-0025 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| GLYCOLIC Acid 70 Skin Chemical Peel | HUMAN OTC DRUG LABEL | 1 | 84785-0026 | SOLUTION | 0.30 mg | TOPICAL | OTC Monograph Drug | 8 sections |
| FEELSHION Glycolic Acid Exfoliating Face Pads | HUMAN OTC DRUG LABEL | 5 | 85212-0009 | PATCH | 1 g | EXTRACORPOREAL | OTC Monograph Drug | 8 sections |