dodecanoic acid Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4642 143-07-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dodecanoic acid
  • lauric acid
  • laurostearic acid
  • vulvic acid
  • Molecular weight: 200.32
  • Formula: C12H24O2
  • CLOGP: 5.10
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 1
  • TPSA: 37.30
  • ALOGS: -4.30
  • ROTB: 10

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:33282 antibacterials
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:84735 algal metabolites

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.76 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Peroxisome proliferator-activated receptor gamma Nuclear hormone receptor IC50 4.52 CHEMBL
Peroxisome proliferator-activated receptor alpha Nuclear hormone receptor IC50 4.52 CHEMBL
Peroxisome proliferator-activated receptor delta Nuclear hormone receptor IC50 4.52 CHEMBL

External reference:

IDSource
C0023139 UMLSCUI
CHEBI:30805 CHEBI
DAO PDB_CHEM_ID
CHEMBL108766 ChEMBL_ID
DB03017 DRUGBANK_ID
C030358 MESH_SUPPLEMENTAL_RECORD_UI
3893 PUBCHEM_CID
5534 IUPHAR_LIGAND_ID
1160N9NU9U UNII
1363435 RXNORM
006214 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Vitafol Plus HUMAN PRESCRIPTION DRUG LABEL 17 0642-0092 CAPSULE, LIQUID FILLED 60 mg ORAL UNULLPPROVED DRUG OTHER 13 sections