levmetamfetamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anorexics 4641 33817-09-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • l-Desoxyephedrine
  • levmetamfetamine
  • (R)-Deoxyephedrine
  • (R)-Methamphetamine
  • (R)-Methylamphetamine
  • D-Methamphetamine
  • l-Methamphetamine
  • l-Methylamphetamine
  • levomethamphetamine
sympathomimetic vasoconstrictor used as nasal decongestant
  • Molecular weight: 149.24
  • Formula: C10H15N
  • CLOGP: 1.89
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 12.03
  • ALOGS: -2.21
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Nasal congestion indication 68235000




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.73 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Trace amine-associated receptor 1 GPCR AGONIST EC50 5.48 CHEMBL SCIENTIFIC LITERATURE
Trace amine-associated receptor 1 GPCR EC50 5.60 CHEMBL
Trace amine-associated receptor 1 GPCR EC50 6.63 CHEMBL
Trace amine-associated receptor 1 GPCR EC50 6.07 CHEMBL

External reference:

IDSource
D02291 KEGG_DRUG
CHEBI:136013 CHEBI
CHEMBL1927030 ChEMBL_ID
7900 INN_ID
DB09571 DRUGBANK_ID
Y24T9BT2Q2 UNII
36604 PUBCHEM_CID
1314416 RXNORM
17315 MMSL
7551 MMSL
001838 NDDF
012299 NDDF
386994006 SNOMEDCT_US
386995007 SNOMEDCT_US
C0724614 UMLSCUI

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Vapor Inhaler HUMAN OTC DRUG LABEL 1 0363-0564 INHALANT 50 mg NASAL OTC monograph final 13 sections
Sinu Inhaler HUMAN OTC DRUG LABEL 1 13709-281 INHALANT 50 mg NASAL OTC monograph final 13 sections
Vapor Inhaler levmetamfetamine nasal decongestant, TopCare health HUMAN OTC DRUG LABEL 1 36800-294 INHALANT 50 mg NASAL OTC monograph final 13 sections
Vapor Inhaler levmetamfetamine nasal decongestant, Equaline HUMAN OTC DRUG LABEL 1 41163-031 INHALANT 50 mg NASAL OTC monograph final 13 sections
Vapor Inhaler HUMAN OTC DRUG LABEL 1 49781-045 INHALANT 50 mg NASAL OTC monograph final 13 sections
Vapor Inhaler levmetamfetamine nasal decongestant, Good Sense HUMAN OTC DRUG LABEL 1 50804-281 INHALANT 50 mg NASAL OTC monograph final 14 sections
Nasal Decongestant Inhaler HUMAN OTC DRUG LABEL 1 54884-050 INHALANT 50 mg NASAL OTC monograph final 13 sections
Vapor Inhaler levmetamfetamine nasal decongestant, DG health HUMAN OTC DRUG LABEL 1 55910-265 INHALANT 50 mg NASAL OTC monograph final 14 sections
Vapor Inhaler HUMAN OTC DRUG LABEL 1 63868-267 INHALANT 50 mg NASAL OTC monograph final 13 sections
Vapor Inhaler levmetamfetamine nasal decongestant, Best Choice HUMAN OTC DRUG LABEL 1 63941-981 INHALANT 50 mg NASAL OTC monograph final 14 sections