oftasceine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
fluorescent imaging agents, fluorescein derivatives 4639 1461-15-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oftasceine
  • calcein
  • fluorexon
  • Molecular weight: 622.54
  • Formula: C30H26N2O13
  • CLOGP: -1.67
  • LIPINSKI: 3
  • HAC: 15
  • HDO: 6
  • TPSA: 231.67
  • ALOGS: -4.18
  • ROTB: 12

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D004396 Coloring Agents
MeSH PA D005456 Fluorescent Dyes
MeSH PA D007202 Indicators and Reagents
MeSH PA D049408 Luminescent Agents
CHEBI has role CHEBI:51217 fluorochromes

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.28 acidic
pKa2 1.88 acidic
pKa3 2.47 acidic
pKa4 3.07 acidic
pKa5 6.46 acidic
pKa6 7.07 acidic
pKa7 11.82 Basic
pKa8 11.22 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:51903 CHEBI
CHEMBL1973733 ChEMBL_ID
C007740 MESH_SUPPLEMENTAL_RECORD_UI
4573 INN_ID
DB11184 DRUGBANK_ID
V0YM2B16TS UNII
1367088 RXNORM
012767 NDDF
C2365117 UMLSCUI
65079 PUBCHEM_CID

Pharmaceutical products:

None