rose bengal 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4637	632-69-9

Description:

Molecule

Description

Synonyms:

rose bengal
Rose Bengal disodium
Rose Bengal sodium
Sodium tetraiodotetrachlorofluorescein

A bright bluish pink compound that has been used as a dye, biological stain, and diagnostic aid.

Molecular weight: 1017.63
Formula: C20H2Cl4I4Na2O5
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 89.49
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	S01JA02	SENSORY ORGANS OPHTHALMOLOGICALS DIAGNOSTIC AGENTS Colouring agents
MeSH PA	D004396	Coloring Agents
MeSH PA	D005456	Fluorescent Dyes
MeSH PA	D007202	Indicators and Reagents
MeSH PA	D049408	Luminescent Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Chymotrypsin C	Enzyme	Q99895	CTRC_HUMAN		IC50	4.30		CHEMBL
Beta-galactosidase	Enzyme	P16278	BGAL_HUMAN		IC50	4.10		CHEMBL
Poly(ADP-ribose) glycohydrolase	Enzyme	Q86W56	PARG_HUMAN		IC50	4.53		CHEMBL
Beta-lactamase	Enzyme		AMPC_ECOLI		IC50	6.33		CHEMBL
Vesicular acetylcholine transporter	Transporter		VACHT_RAT		IC50	5.01		CHEMBL
Protein translocase subunit SecA 1	Unclassified		SECA1_STAA8		IC50	6.30		CHEMBL
Protein translocase subunit SecA 2	Unclassified		SECA2_STAA8		IC50	5.70		CHEMBL

External reference:

ID	Source
4019275	VUID
N0000147474	NUI
4019275	VANDF
CHEMBL1208422	ChEMBL_ID
CHEMBL1160160	ChEMBL_ID
DB11182	DRUGBANK_ID
1362690	RXNORM
5073	MMSL
5436	MMSL
002215	NDDF
013981	NDDF
330888007	SNOMEDCT_US
408742009	SNOMEDCT_US
C0035857	UMLSCUI
D012395	MESH_DESCRIPTOR_UI
CHEMBL2359093	ChEMBL_ID
25474	PUBCHEM_CID
11874	INN_ID
956575SN5L	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
GloStrips	HUMAN PRESCRIPTION DRUG LABEL	1	51801-004	STRIP	1.30 mg	OPHTHALMIC	UNAPPROVED DRUG OTHER	10 sections