sodium pyrophosphate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4630 7722-88-5

Description:

MoleculeDescription

Synonyms:

  • sodium pyrophosphate
  • sodium diphosphate
  • tetrasodium diphosphate
  • tetrasodium pyrophosphate
  • Molecular weight: 265.90
  • Formula: Na4O7P2
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 135.61
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Respiratory tract infection bacterial 106.01 36.31 18 351 1764 34954798
Respiratory tract infection viral 99.80 36.31 18 351 2499 34954063
Respiratory tract infection 67.47 36.31 19 350 19693 34936869
Cytokine release syndrome 51.68 36.31 16 353 22861 34933701

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Respiratory tract infection bacterial 107.46 30.31 18 641 2059 79741670
Respiratory tract infection viral 94.55 30.31 18 641 4241 79739488
Cytokine release syndrome 60.55 30.31 19 640 35979 79707750
Respiratory tract infection 54.91 30.31 19 640 48670 79695059
Pulmonary embolism 31.96 30.31 19 640 171635 79572094

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:38161 Chelating agent
CHEBI has role CHEBI:63047 food emulsifiers
CHEBI has role CHEBI:77970 thickening agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Farnesyl pyrophosphate synthase Enzyme Ki 4.53 CHEMBL

External reference:

IDSource
D05873 KEGG_DRUG
4020402 VUID
N0000179245 NUI
4019113 VANDF
CHEBI:71240 CHEBI
CHEMBL450079 ChEMBL_ID
C003319 MESH_SUPPLEMENTAL_RECORD_UI
O352864B8Z UNII
1364532 RXNORM
28992 MMSL
NOCODE MMSL
004831 NDDF
009844 NDDF
C0074764 UMLSCUI
24403 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Pyrophosphate HUMAN PRESCRIPTION DRUG LABEL 1 51808-218 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 27.60 mg INTRAVENOUS Unapproved drug other 5 sections
Technescan PYP HUMAN PRESCRIPTION DRUG LABEL 2 69945-094 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 11.90 mg INTRAVENOUS NDA 17 sections
EXODEN ALL IN ONE HUMAN OTC DRUG LABEL 4 70602-010 PASTE 3.40 g TOPICAL unapproved drug other 8 sections
ONETOOTHCLINIC TOOTH HUMAN OTC DRUG LABEL 3 73527-0001 PASTE 0.50 g DENTAL unapproved drug other 7 sections
ONETOOTH CLINIC TOOTH HUMAN OTC DRUG LABEL 3 73527-0002 PASTE 0.50 g DENTAL unapproved drug other 7 sections
MIMIBO PREMIUM TOOTH HUMAN OTC DRUG LABEL 3 73527-0003 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
MIMIBO PREMIUM TOOTH HUMAN OTC DRUG LABEL 3 73527-0004 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
DR.CHOIS TOOTHPASTE CARE PLUS HUMAN OTC DRUG LABEL 3 73666-0500 PASTE, DENTIFRICE 0.50 g TOPICAL unapproved drug other 10 sections
DR.CHOIS TOOTHPASTE CARE HUMAN OTC DRUG LABEL 3 73666-0510 PASTE, DENTIFRICE 0.50 g TOPICAL unapproved drug other 10 sections
DR.CHOIS TOOTHPASTE FRESH HUMAN OTC DRUG LABEL 4 73666-0520 PASTE, DENTIFRICE 0.50 g TOPICAL unapproved drug other 10 sections
ORAL PROJEQT O1 TOOTHPASTETABLETS HUMAN OTC DRUG LABEL 4 76058-500 TABLET 1 g ORAL unapproved drug other 7 sections
Dr. DADDYS Tooth HUMAN OTC DRUG LABEL 2 76884-0003 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Dr. DADDYS GumToothpaste HUMAN OTC DRUG LABEL 4 76884-0006 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Dr.DADDYS Junior Toothpaste(Mint flavor) HUMAN OTC DRUG LABEL 3 76884-0007 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Dr. DADDYS Junior Toothpaste(Green grape) HUMAN OTC DRUG LABEL 3 76884-0008 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Dr. DADDYS Kids Tooth HUMAN OTC DRUG LABEL 3 76884-0010 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Dr. DADDYS Kids Toothpaste(Raspberry flavor) HUMAN OTC DRUG LABEL 3 76884-0011 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Dr. DADDYS GumToothpaste HUMAN OTC DRUG LABEL 4 76884-0012 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Mastikis Gold II HUMAN OTC DRUG LABEL 2 79814-002 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 8 sections
Mastikis Qingjie Shine Mastic HUMAN OTC DRUG LABEL 3 79814-004 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 8 sections
Mastikids II HUMAN OTC DRUG LABEL 3 79814-005 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 8 sections
Mastikis Qingxin Care Mastic HUMAN OTC DRUG LABEL 3 79814-006 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 8 sections
Vontee HUMAN OTC DRUG LABEL 4 80687-010 TABLET 1 g ORAL unapproved drug other 10 sections
QUANTUMTOOTHCARE TOOTH HUMAN OTC DRUG LABEL 3 81659-0001 PASTE, DENTIFRICE 0.50 g DENTAL unapproved drug other 7 sections
Dr.NOAH SOLIDTOOTHPASTE HUMAN OTC DRUG LABEL 4 82359-0003 TABLET 0.01 g ORAL unapproved drug other 7 sections
Toosty Rucola Toothpaste HUMAN OTC DRUG LABEL 4 82662-020 PASTE, DENTIFRICE 0.50 g ORAL unapproved drug other 10 sections
Innoble ONECHEWTOOTHPASTE HUMAN OTC DRUG LABEL 4 82709-001 TABLET 1 g ORAL unapproved drug other 7 sections