trinitrophenol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4626 88-89-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • trinitrophenol
  • picric acid
  • picronitric acid
  • carbazotic acid
used as antiseptic, astringent & stimulant for epitheliazation; structure
  • Molecular weight: 229.10
  • Formula: C6H3N3O7
  • CLOGP: 1.64
  • LIPINSKI: 0
  • HAC: 10
  • HDO: 1
  • TPSA: 157.69
  • ALOGS: -3.07
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Periarthritis 49.93 48.18 8 181 1076 34955666

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D007202 Indicators and Reagents
MeSH PA D014475 Uncoupling Agents
CHEBI has role CHEBI:48218 antiseptics
CHEBI has role CHEBI:50913 fixating agent
CHEBI has role CHEBI:63490 explosive compounds

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 1.16 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:46149 CHEBI
TNF PDB_CHEM_ID
CHEMBL108541 ChEMBL_ID
C005858 MESH_SUPPLEMENTAL_RECORD_UI
DB03651 DRUGBANK_ID
1320642 RXNORM
NOCODE MMSL
002431 NDDF
C0071044 UMLSCUI
6954 PUBCHEM_CID
A49OS0F91S UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Nitrotan HUMAN OTC DRUG LABEL 4 11960-0049 AEROSOL, SPRAY 0.00 g TOPICAL OTC monograph not final 9 sections
San Su HUMAN OTC DRUG LABEL 1 72942-0001 POWDER 13 g ORAL unapproved drug other 7 sections