stearic acid Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4611 57-11-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • stearic acid
  • octadecanoic acid
  • Molecular weight: 284.48
  • Formula: C18H36O2
  • CLOGP: 8.27
  • LIPINSKI: 1
  • HAC: 2
  • HDO: 1
  • TPSA: 37.30
  • ALOGS: -6.63
  • ROTB: 16

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.76 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Peroxisome proliferator-activated receptor gamma Nuclear hormone receptor IC50 4.52 CHEMBL
Peroxisome proliferator-activated receptor alpha Nuclear hormone receptor IC50 5.96 CHEMBL
Peroxisome proliferator-activated receptor delta Nuclear hormone receptor IC50 5.22 CHEMBL
Fatty acid-binding protein, adipocyte Cytosolic other Kd 4.10 CHEMBL

External reference:

IDSource
D00119 KEGG_DRUG
4020443 VUID
N0000178989 NUI
C0038229 UMLSCUI
4ELV7Z65AP UNII
CHEMBL46403 ChEMBL_ID
C031183 MESH_SUPPLEMENTAL_RECORD_UI
STE PDB_CHEM_ID
DB03193 DRUGBANK_ID
CHEBI:28842 CHEBI
5281 PUBCHEM_CID
3377 IUPHAR_LIGAND_ID
420674004 SNOMEDCT_US
4020443 VANDF
NOCODE MMSL
259577009 SNOMEDCT_US
003887 NDDF
1310551 RXNORM

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ISA KNOX AGELESS SERUM MAKEUP BASE 10 HUMAN OTC DRUG LABEL 6 53208-471 CREAM 0.18 mL TOPICAL OTC monograph not final 5 sections
ISAKNOX AGELESS SERUM MOIST PEARL BASE HUMAN OTC DRUG LABEL 6 53208-478 LIQUID 0.18 mL TOPICAL OTC monograph not final 5 sections
Sha-lem HUMAN OTC DRUG LABEL 3 59862-100 OINTMENT 7.25 g TOPICAL unapproved drug other 10 sections
Jinhwagwangsu Bubble HUMAN OTC DRUG LABEL 1 69871-001 SOAP 120 mg TOPICAL unapproved drug other 7 sections
Obeo Baby Bubble HUMAN OTC DRUG LABEL 1 69871-002 SOAP 120 mg TOPICAL unapproved drug other 7 sections
Jinhwagwangsu Hair HUMAN OTC DRUG LABEL 1 69871-004 SOAP 12 g TOPICAL unapproved drug other 7 sections
ZENOL POWERFULX RECOVERYCREAM HUMAN OTC DRUG LABEL 1 70042-0001 CREAM 1.50 g TOPICAL unapproved drug other 7 sections
RECOVERY HUMAN OTC DRUG LABEL 1 70042-0002 CREAM 1.50 g TOPICAL unapproved drug other 7 sections
Doctor Plus HUMAN OTC DRUG LABEL 1 70042-6001 CREAM 1.50 g TOPICAL unapproved drug other 7 sections
CELLBN FIRST CARE CLEANSER HUMAN OTC DRUG LABEL 1 71450-0006 CREAM 16 g TOPICAL unapproved drug other 7 sections