xylitol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4604 | 87-99-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:50505 | sweeteners |
| CHEBI has role | CHEBI:50904 | alergeno |
| CHEBI has role | CHEBI:59174 | haptens |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:75772 | S. cerevisiae metabolites |
| CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
| CHEBI has role | CHEBI:84735 | algal metabolites |
| MeSH PA | D005421 | Flavoring Agents |
| MeSH PA | D005503 | Food Additives |
| MeSH PA | D013549 | Sweetening Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Prevention of dental caries | indication | 426482000 | |
| Gingivitis | off-label use | 66383009 | DOID:3087 |
| Dental Plaque Prevention | off-label use | ||
| Dental fluorosis | contraindication | 30265004 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.28 | acidic |
| pKa2 | 13.89 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D00061 | KEGG_DRUG |
| 4020499 | VUID |
| N0000148228 | NUI |
| 4020499 | VANDF |
| CHEBI:17151 | CHEBI |
| XYL | PDB_CHEM_ID |
| CHEMBL96783 | ChEMBL_ID |
| DB11195 | DRUGBANK_ID |
| VCQ006KQ1E | UNII |
| 11377 | RXNORM |
| 26100 | MMSL |
| NOCODE | MMSL |
| d07373 | MMSL |
| 006331 | NDDF |
| 395951005 | SNOMEDCT_US |
| 398986008 | SNOMEDCT_US |
| C0043369 | UMLSCUI |
| D014993 | MESH_DESCRIPTOR_UI |
| 6912 | PUBCHEM_CID |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Noble G Plus | HUMAN OTC DRUG LABEL | 1 | 60319-3001 | PASTE, DENTIFRICE | 0.70 g | DENTAL | unapproved drug other | 8 sections |
| Noble 1 Plus | HUMAN OTC DRUG LABEL | 1 | 60319-4001 | POWDER, DENTIFRICE | 0.70 g | DENTAL | unapproved drug other | 9 sections |
| YUMAKI ORIGINAL MINT TOOTH | HUMAN OTC DRUG LABEL | 7 | 71746-010 | PASTE, DENTIFRICE | 0.10 g | TOPICAL | unapproved drug other | 8 sections |
| ADEA GARGLE | HUMAN OTC DRUG LABEL | 2 | 72191-0100 | TABLET, CHEWABLE | 5 g | ORAL | unapproved drug other | 7 sections |
| LECLAT Rose Toothpaste | HUMAN OTC DRUG LABEL | 3 | 73175-010 | PASTE, DENTIFRICE | 0.50 g | ORAL | unapproved drug other | 8 sections |
| LECLAT Imperial Toothpaste | HUMAN OTC DRUG LABEL | 3 | 73175-020 | PASTE, DENTIFRICE | 0.50 g | ORAL | unapproved drug other | 8 sections |
| LECLAT Blanc Toothpaste | HUMAN OTC DRUG LABEL | 3 | 73175-030 | PASTE, DENTIFRICE | 0.50 g | ORAL | unapproved drug other | 8 sections |
| CELRAUM PHEROMONE FRAGRANCE LOVELY PERFUME | HUMAN OTC DRUG LABEL | 6 | 75368-040 | SHAMPOO | 0.02 g | TOPICAL | unapproved drug other | 9 sections |
| CHI. JOA (Anti-inflammatory effect, antibacterial effect, stomatitis improvement, plaque removal) | HUMAN OTC DRUG LABEL | 10 | 77008-4285 | POWDER | 1 g | TOPICAL | unapproved drug other | 6 sections |
| Hoo gargle (Mouthwash) | HUMAN OTC DRUG LABEL | 1 | 81840-1001 | LIQUID | 1 g | DENTAL | unapproved drug other | 7 sections |
| Hoo gargle (Rooibos Tea Flavor)(Mouthwash) | HUMAN OTC DRUG LABEL | 1 | 81840-1003 | LIQUID | 1 g | DENTAL | unapproved drug other | 7 sections |
| Hoo gargle (Jasmine Flavor)(Mouthwash) | HUMAN OTC DRUG LABEL | 1 | 81840-1022 | LIQUID | 1 g | DENTAL | unapproved drug other | 7 sections |
| BOP whiteningtoothpaste | HUMAN OTC DRUG LABEL | 2 | 82574-001 | GEL | 3 g | TOPICAL | unapproved drug other | 8 sections |
| Lab52 Anti-Cavity Oral Care | HUMAN OTC DRUG LABEL | 2 | 82711-001 | AEROSOL | 12 g | DENTAL | unapproved drug other | 8 sections |
| Lab52 Anti-Sensitivity Oral Care | HUMAN OTC DRUG LABEL | 3 | 82711-002 | AEROSOL | 10 g | DENTAL | unapproved drug other | 9 sections |
| Lab52 Kids Oral Protection | HUMAN OTC DRUG LABEL | 2 | 82711-006 | AEROSOL | 10 g | DENTAL | unapproved drug other | 11 sections |
| Lab52 Kids Oral Protection | HUMAN OTC DRUG LABEL | 2 | 82711-007 | AEROSOL | 10 g | DENTAL | unapproved drug other | 10 sections |
| Lab52 Kids Oral Protection | HUMAN OTC DRUG LABEL | 2 | 82711-008 | AEROSOL | 10 g | DENTAL | unapproved drug other | 10 sections |