xylitol Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4604 87-99-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • xylitol
A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.
  • Molecular weight: 152.15
  • Formula: C5H12O5
  • CLOGP: -1.88
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 5
  • TPSA: 101.15
  • ALOGS: 0.64
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D005421 Flavoring Agents
MeSH PA D005503 Food Additives
CHEBI has role CHEBI:50505 sweetening agent
MeSH PA D013549 Sweetening Agents

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Prevention of dental caries indication 426482000
Gingivitis off-label use 66383009 DOID:3087
Dental Plaque Prevention off-label use
Dental fluorosis contraindication 30265004

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.28 acidic
pKa2 13.89 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00061 KEGG_DRUG
4020499 VUID
N0000148228 NUI
C0043369 UMLSCUI
CHEMBL96783 ChEMBL_ID
VCQ006KQ1E UNII
DB11195 DRUGBANK_ID
CHEBI:17151 CHEBI
D014993 MESH_DESCRIPTOR_UI
6912 PUBCHEM_CID
398986008 SNOMEDCT_US
4020499 VANDF
NOCODE MMSL
26100 MMSL
d07373 MMSL
11377 RXNORM
395951005 SNOMEDCT_US
006331 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Noble G Plus HUMAN OTC DRUG LABEL 1 60319-3001 PASTE, DENTIFRICE 0.70 g DENTAL unapproved drug other 7 sections
Noble 1 Plus HUMAN OTC DRUG LABEL 1 60319-4001 POWDER, DENTIFRICE 0.70 g DENTAL unapproved drug other 9 sections
YUMAKI ORIGINAL MINT TOOTH HUMAN OTC DRUG LABEL 4 71746-010 PASTE, DENTIFRICE 0.10 g TOPICAL unapproved drug other 8 sections
ADEA GARGLE HUMAN OTC DRUG LABEL 2 72191-0100 TABLET, CHEWABLE 5 g ORAL unapproved drug other 7 sections
L'ECLAT Rose Toothpaste HUMAN OTC DRUG LABEL 3 73175-010 PASTE, DENTIFRICE 0.50 g ORAL unapproved drug other 8 sections
L'ECLAT Imperial Toothpaste HUMAN OTC DRUG LABEL 3 73175-020 PASTE, DENTIFRICE 0.50 g ORAL unapproved drug other 8 sections
L'ECLAT Blanc Toothpaste HUMAN OTC DRUG LABEL 3 73175-030 PASTE, DENTIFRICE 0.50 g ORAL unapproved drug other 8 sections