diethylamino hydroxybenzoyl hexyl benzoate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4602 302776-68-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • diethylamino hydroxybenzoyl hexyl benzoate
a UV filtering agent
  • Molecular weight: 397.52
  • Formula: C24H31NO4
  • CLOGP: 7.08
  • LIPINSKI: 1
  • HAC: 5
  • HDO: 1
  • TPSA: 66.84
  • ALOGS: -4.75
  • ROTB: 12

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT1,AKT2,AKT3,ALK,AURKA,AURKB,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK4,CDK5,CDK9,CHEK1,CSF1R,DDR1,DYRK1B,EIF2AK3,EPHA2,EPHB4,ERBB2,FGFR1,FLT3,GRK2,GSK3B,INSR,ITK,JAK1,JAK2,JAK3,KIT,MAP2K6,MAP3K1,MAP3K11,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAPK1,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MAPKAPK5,MARK4,MELK,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIM2,PLK1,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ULK2,ZAP70 79
kinase-selectivity-class AXL,BRAF,CAMK2D,CDK4,CDK9,DDR1,EIF2AK3,EPHB4,ERBB2,GRK2,MAP2K6,MAPK12,MAPK7,MARK4,MTOR,PDK4,SIK2,STK10,STK33,TEK,TTK,ULK1 22
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.68 acidic
pKa2 4.03 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C000597744 MESH_SUPPLEMENTAL_RECORD_UI
DB11269 DRUGBANK_ID
ANQ870JD20 UNII
1426392 RXNORM
C2980749 UMLSCUI
10111431 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types HUMAN OTC DRUG LABEL 7 49967-123 LOTION 30 mg TOPICAL export only 4 sections
Kiehls Ultra Light Daily UV Defense CC SPF 50 Anti Pollution HUMAN OTC DRUG LABEL 6 49967-161 CREAM 5 mg TOPICAL export only 4 sections
Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types HUMAN OTC DRUG LABEL 7 49967-309 LOTION 30 mg TOPICAL export only 4 sections
KIEHLS DERMATOLOGIST SOLUTIONS ULTRA LIGHT DAILY UV DEFENSE SUNSCREEN SPF 50 HIGH PROTECTION ANTI-POLLUTION LIGHTWEIGHT FORMULA FOR ALL SKIN TYPES HUMAN OTC DRUG LABEL 6 49967-449 LOTION 5 mg TOPICAL export only 4 sections
The History of Whoo Jin Hae Yoon Sun HUMAN OTC DRUG LABEL 5 53208-503 CREAM 1 mL TOPICAL OTC monograph not final 5 sections
OHUI THE FIRST CELL REVOLUTION AGE CONTROL SUN BLOCK HUMAN OTC DRUG LABEL 6 53208-515 CREAM 0.50 g TOPICAL OTC monograph not final 5 sections
OHUI SUNSCIENCE LUMINOUS WHITENING SUNBLOCK HUMAN OTC DRUG LABEL 8 53208-518 CREAM 1 mL TOPICAL OTC monograph not final 5 sections
SOORYEHAN HYO FERMENTED SUN BLOCK HUMAN OTC DRUG LABEL 7 53208-549 CREAM 1 mL TOPICAL OTC monograph not final 7 sections
D-ONE BY TAMDOAN SUNSCREEN 50 HUMAN OTC DRUG LABEL 8 70931-0001 CREAM 2 g TOPICAL unapproved drug other 8 sections
D-ONE BY TAMDOAN BB MEDIUM HUMAN OTC DRUG LABEL 8 70931-0003 CREAM 2 g TOPICAL unapproved drug other 7 sections
Wonder Intensive BBCream 21 (Light) HUMAN OTC DRUG LABEL 8 70931-0005 CREAM 2 g TOPICAL unapproved drug other 7 sections
P.CALM Water Barrier Suncream HUMAN OTC DRUG LABEL 5 83735-001 CREAM 10 mg TOPICAL unapproved drug other 7 sections
Pfect A solar barrier Serum Textured HUMAN OTC DRUG LABEL 2 84755-0002 ELIXIR 2.50 mg TOPICAL unapproved drug other 8 sections
Pfect A solar barrier Serum Textured HUMAN OTC DRUG LABEL 2 84755-0002 ELIXIR 2.50 mg TOPICAL unapproved drug other 8 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 84755-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 84755-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections
Centella Sunscreen SPF 50 HUMAN OTC DRUG LABEL 5 85473-442 CREAM 1 g CUTANEOUS OTC Monograph Drug 7 sections
Calming Days Vegan Sunscreen HUMAN OTC DRUG LABEL 4 85940-307 GEL 3 g TOPICAL OTC Monograph Drug 10 sections
Pfect A solar barrier Serum Textured HUMAN OTC DRUG LABEL 2 87565-0002 ELIXIR 2.50 mg TOPICAL unapproved drug other 8 sections
Beauty Body Factorie Body Shield SPF HUMAN OTC DRUG LABEL 5 87565-0006 LOTION 30 mg TOPICAL unapproved drug other 8 sections