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mannosulfan 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antineoplastic, alkylating agents, methanesulfonates | 4598 | 7518-35-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
minor descriptor (75-84); on-line & Index Medicus search METHANESULFONATES (75-84)
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AXL,BRAF,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,ERBB2,GRK2,ITK,MAP2K6,MAP3K21,MAPK10,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CG,PRKDC,TEK | 22 | |||
| kinase-selectivity-class | AXL,BMX,BRAF,CDK1,CDK16,CDK2,CDK3,CDK4,CDK6,CDK9,CHUK,DYRK1A,GRK2,IRAK3,MAP2K6,MAP3K21,PDK1,PIK3CD,PIK3CG,PRKDC,SYK,TEK,ZAP70 | 23 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | L01AB03 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS ANTINEOPLASTIC AGENTS ALKYLATING AGENTS Alkyl sulfonates |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
Related Drugs by ATC class:
L01AB Alkyl sulfonates 2 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.4 | acidic |
| pKa2 | 13.95 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07071 | KEGG_DRUG |
| CHEBI:136005 | CHEBI |
| CHEMBL460282 | ChEMBL_ID |
| C100121 | MESH_SUPPLEMENTAL_RECORD_UI |
| 2968 | INN_ID |
| DB13334 | DRUGBANK_ID |
| 135FQ40L36 | UNII |
| C0065696 | UMLSCUI |
| 20055482 | PUBCHEM_CID |
Pharmaceutical products:
None