levomethadone Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4586 | 125-58-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 15 | mg | O |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N07BC05 | NERVOUS SYSTEM OTHER NERVOUS SYSTEM DRUGS DRUGS USED IN ADDICTIVE DISORDERS Drugs used in opioid dependence |
| CHEBI has role | CHEBI:35482 | narcotic analgesics |
| CHEBI has role | CHEBI:51177 | cough suppressant |
| CHEBI has role | CHEBI:55322 | mu opioid agonist |
| CHEBI has role | CHEBI:60643 | n-methyl-d-aspartate receptor antagonists |
Drug Use (View source of the data)
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Opioid dependence | indication | 75544000 | DOID:2559 |
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.55 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Opioid receptor | GPCR | Ki | 8.70 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D08121 | KEGG_DRUG |
| 5967-73-7 | SECONDARY_CAS_RN |
| C0772241 | UMLSCUI |
| CHEBI:136003 | CHEBI |
| CHEMBL159659 | ChEMBL_ID |
| DB13515 | DRUGBANK_ID |
| 5002 | INN_ID |
| 6Y75Z4E8NS | UNII |
| 22267 | PUBCHEM_CID |
| 236913 | RXNORM |
| 007175 | NDDF |
| 007176 | NDDF |
Pharmaceutical products:
None